{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T22:11:41Z","timestamp":1792188701395,"version":"4.4.0"},"reference-count":66,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1016\/j.jad.2020.01.032","type":"journal-article","created":{"date-parts":[[2020,1,14]],"date-time":"2020-01-14T20:18:42Z","timestamp":1579033122000},"page":"395-401","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":614,"special_numbering":"C","title":["Sensitivity to change and minimal clinically important difference of the 7-item Generalized Anxiety Disorder Questionnaire (GAD-7)"],"prefix":"10.1016","volume":"265","author":[{"given":"Anne","family":"Toussaint","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"H\u00fcsing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antje","family":"Gumz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katja","family":"Wingenfeld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"H\u00e4rter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Schramm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernd","family":"L\u00f6we","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jad.2020.01.032_bib0001","series-title":"Diagnostic and Statistical Manual of Mental Disorders DSM-IV-TR","year":"2000"},{"key":"10.1016\/j.jad.2020.01.032_bib0002","series-title":"Diagnostic and Statistical Manual of Mental Disorders (DSM-5)","year":"2013"},{"key":"10.1016\/j.jad.2020.01.032_bib0003","doi-asserted-by":"crossref","first-page":"2163","DOI":"10.1176\/appi.ajp.161.12.2163","article-title":"The Hamilton Depression Rating Scale: has the gold standard become a lead weight?","volume":"161","author":"Bagby","year":"2004","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.jad.2020.01.032_bib0004","unstructured":"Baldwin, D., 2018. Generalized anxiety disorder in adults: epidemiology, pathogenesis, clinical manifestations, course, assessment, and diagnosis. UpToDate, Waltham, MA. https:\/\/www.uptodate.com\/contents\/generalizedanxiety-disorder-in-adults-epidemiology-pathogenesis-clinical-manifestations-courseassessment-and-diagnosis?search=pathophysiology%20anxiety&source=search_result&selectedTitle=1~150&usage_type=default&display_rank=1(accessed 09 April 2019)."},{"key":"10.1016\/j.jad.2020.01.032_bib0005","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1056\/NEJMp1611252","article-title":"Patient-reported outcomes - harnessing patients' voices to improve clinical care","volume":"376","author":"Basch","year":"2017","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jad.2020.01.032_bib0006","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.janxdis.2014.06.002","article-title":"Beyond generalized anxiety disorder: psychometric properties of the GAD-7 in a heterogeneous psychiatric sample","volume":"28","author":"Beard","year":"2014","journal-title":"J. Anxiety Disord."},{"key":"10.1016\/j.jad.2020.01.032_bib0007","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1007\/s11136-015-1168-3","article-title":"Patient-reported outcomes: pathways to better health, better services, and better societies","volume":"25","author":"Black","year":"2016","journal-title":"Qual. Life Res."},{"key":"10.1016\/j.jad.2020.01.032_bib0008","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/j.1600-0447.1988.tb05089.x","article-title":"The differentiation of anxiety and depression by rating scales","volume":"77","author":"Bramley","year":"1988","journal-title":"Acta Psychiat. Scand."},{"key":"10.1016\/j.jad.2020.01.032_bib0009","first-page":"16","article-title":"Biological basis of generalized anxiety disorder","volume":"58","author":"Brawman-Mintzer","year":"1997","journal-title":"J. Clin. Psych."},{"key":"10.1016\/j.jad.2020.01.032_bib0010","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1097\/j.pain.0000000000001121","article-title":"Estimating minimally important differences for the PROMIS pain interference scales: results from 3 randomized clinical trials","volume":"159","author":"Chen","year":"2018","journal-title":"Pain"},{"key":"10.1016\/j.jad.2020.01.032_bib0013","doi-asserted-by":"crossref","first-page":"375","DOI":"10.3109\/09540261.2011.606803","article-title":"Implementing NICE guidelines for the psychological treatment of depression and anxiety disorders: the IAPT experience","volume":"23","author":"Clark","year":"2011","journal-title":"Int Rev Psychiatry"},{"key":"10.1016\/j.jad.2020.01.032_bib0012","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1016\/j.brat.2009.07.010","article-title":"Improving access to psychological therapy: initial evaluation of two UK demonstration sites","volume":"47","author":"Clark","year":"2009","journal-title":"Behav. Res. Ther."},{"key":"10.1016\/j.jad.2020.01.032_bib0011","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1037\/0021-843X.100.3.316","article-title":"Tripartite model of anxiety and depression: psychometric evidence and taxonomic implications","volume":"100","author":"Clark","year":"1991","journal-title":"J. Abnorm. Psychol."},{"key":"10.1016\/j.jad.2020.01.032_bib0014","series-title":"Statistical Power Analysis for the Behavioral Sciences","author":"Cohen","year":"1988"},{"key":"10.1016\/j.jad.2020.01.032_bib0015","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1179\/jmt.2008.16.4.82E","article-title":"Clinimetrics corner: the minimal clinically important change score (MCID): a necessary pretense","volume":"16","author":"Cook","year":"2008","journal-title":"J. Man. Manip. Ther."},{"key":"10.1016\/j.jad.2020.01.032_bib0016","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1002\/da.20633","article-title":"What is an anxiety disorder?","volume":"26","author":"Craske","year":"2009","journal-title":"Depress Anxiety"},{"key":"10.1016\/j.jad.2020.01.032_bib0017","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1080\/16506073.2011.582138","article-title":"Psychometric comparison of the Generalized Anxiety Disorder Scale-7 and the Penn State Worry Questionnaire for measuring response during treatment of generalised anxiety disorder","volume":"40","author":"Dear","year":"2011","journal-title":"Cogn. Behav. Ther."},{"key":"10.1016\/j.jad.2020.01.032_bib0018","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0197-2456(84)90026-6","article-title":"Measuring functional outcomes in therapeutic trials for chronic disease","volume":"5","author":"Deyo","year":"1984","journal-title":"Control. Clin. Trials."},{"key":"10.1016\/j.jad.2020.01.032_bib0019","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/0021-9681(86)90038-X","article-title":"Assessing the responsiveness of functional scales to clinical change: an analogy to diagnostic test performance","volume":"39","author":"Deyo","year":"1986","journal-title":"J. Chronic Dis."},{"key":"10.1016\/j.jad.2020.01.032_bib0020","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1176\/appi.ajp.2007.06111868","article-title":"Difference in treatment outcome in outpatients with anxious versus nonanxious depression: a STAR*D report","volume":"165","author":"Fava","year":"2008","journal-title":"Am. J. Psychiatry."},{"key":"10.1016\/j.jad.2020.01.032_bib0021","series-title":"Biometrics Research","article-title":"Structured clinical interview for DSM-IV-TR Axis I disorders, research version, patient edition (SCID-I\/P)","author":"First","year":"2002"},{"key":"10.1016\/j.jad.2020.01.032_bib0022","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.genhosppsych.2017.07.002","article-title":"Monitoring somatic symptoms in patients with mental disorders: sensitivity to change and minimal clinically important difference of the Somatic Symptom Scale - 8 (SSS-8)","volume":"48","author":"Gierk","year":"2017","journal-title":"Gen. Hosp. Psychiatry."},{"key":"10.1016\/j.jad.2020.01.032_bib0023","doi-asserted-by":"crossref","first-page":"427","DOI":"10.4088\/JCP.v60n0702","article-title":"The economic burden of anxiety disorders in the 1990s","volume":"60","author":"Greenberg","year":"1999","journal-title":"J. Clin. Psychiatry."},{"key":"10.1016\/j.jad.2020.01.032_bib0024","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.brat.2013.06.004","article-title":"Enhancing recovery rates: lessons from year one of IAPT","volume":"51","author":"Gyani","year":"2013","journal-title":"Beh. Res. Ther."},{"key":"10.1016\/j.jad.2020.01.032_bib0025","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1111\/j.2044-8260.1967.tb00530.x","article-title":"Development of a rating scale for primary depressive illness","volume":"6","author":"Hamilton","year":"1967","journal-title":"Br. J. Soc. Clin. Psychol."},{"key":"10.1016\/j.jad.2020.01.032_bib0026","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1371\/journal.pone.0042916","article-title":"Comparative effectiveness of cognitive therapies delivered face-to-face or over the telephone: an observational study using propensity methods","volume":"7","author":"Hammond","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.jad.2020.01.032_bib0027","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.jpsychores.2009.04.013","article-title":"Depression, anxiety, and somatoform disorders: vague or distinct categories in primary care? Results from a large cross-sectional study","volume":"67","author":"Hanel","year":"2009","journal-title":"J. Psychosom. Res."},{"key":"10.1016\/j.jad.2020.01.032_bib0028","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1002\/da.20491","article-title":"The nosological relationship between generalized anxiety disorder and major depression","volume":"25","author":"Hettema","year":"2008","journal-title":"Depress. Anxiety."},{"key":"10.1016\/j.jad.2020.01.032_bib0029","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1177\/135910539800300201","article-title":"The effect size statistic: useful in health outcomes research?","volume":"3","author":"Hevey","year":"1998","journal-title":"J. Health Psychol"},{"key":"10.1016\/j.jad.2020.01.032_bib0030","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.genhosppsych.2018.08.006","article-title":"Validity and sensitivity to change of the Somatic Symptom Disorder-B Criteria Scale (SSD-12) in a clinical population","volume":"55","author":"H\u00fcsing","year":"2018","journal-title":"Gen. Hosp. Psychiatry."},{"key":"10.1016\/j.jad.2020.01.032_bib0031","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1002\/cpp.1802","article-title":"Validity of the Generalized Anxiety Disorder-7 Scale in an acute psychiatric sample","volume":"20","author":"Kertz","year":"2013","journal-title":"Clin. Psychol. Psychother."},{"key":"10.1016\/j.jad.2020.01.032_bib0033","doi-asserted-by":"crossref","first-page":"3095","DOI":"10.1001\/jama.289.23.3095","article-title":"National Comorbidity Survey Replication. The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R)","volume":"289","author":"Kessler","year":"2003","journal-title":"JAMA."},{"key":"10.1016\/j.jad.2020.01.032_bib0034","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1001\/archpsyc.62.6.593","article-title":"Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication","volume":"62","author":"Kessler","year":"2005","journal-title":"Arch. Gen. Psychiatry."},{"key":"10.1016\/j.jad.2020.01.032_bib0035","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1017\/S0033291707002012","article-title":"Co-morbid major depression and generalized anxiety disorders in the National Comorbidity Survey follow-up","volume":"38","author":"Kessler","year":"2008","journal-title":"Psychol. Med."},{"key":"10.1016\/j.jad.2020.01.032_bib0032","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1192\/S0007125000298371","article-title":"Comorbidity of DSM-III-R major depressive disorder in the general population: results from the US National Comorbidity Survey","volume":"30","author":"Kessler","year":"1996","journal-title":"Brit. J. Psychiat."},{"key":"10.1016\/j.jad.2020.01.032_bib0036","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1200\/JCO.2013.53.5948","article-title":"What is the value of the routine use of patient-reported outcome measures toward improvement of patient outcomes, processes of care, and health service outcomes in cancer care? A systematic review of controlled trials","volume":"32","author":"Kotronoulas","year":"2014","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.jad.2020.01.032_bib0039","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.jad.2018.12.098","article-title":"Comparative validity and responsiveness of PHQ-ADS and other composite anxiety-depression measures","volume":"246","author":"Kroenke","year":"2018","journal-title":"J.Affect. Disord."},{"key":"10.1016\/j.jad.2020.01.032_bib0037","doi-asserted-by":"crossref","first-page":"317","DOI":"10.7326\/0003-4819-146-5-200703060-00004","article-title":"Anxiety disorders in primary care: prevalence, impairment, comorbidity, and detection","volume":"146","author":"Kroenke","year":"2007","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.jad.2020.01.032_bib0038","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1097\/PSY.0000000000000322","article-title":"Patient health questionnaire anxiety and depression scale: initial validation in three clinical trials","volume":"78","author":"Kroenke","year":"2016","journal-title":"Psychosom. Med."},{"key":"10.1016\/j.jad.2020.01.032_bib0040","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fpsyg.2013.00863","article-title":"Calculating and reporting effect sizes to facilitate cumulative science: a practical primer for t-tests and ANOVAs","volume":"4","author":"Lakens","year":"2013","journal-title":"Front. Psychol."},{"key":"10.1016\/j.jad.2020.01.032_bib0041","doi-asserted-by":"crossref","first-page":"341","DOI":"10.4088\/JCP.10m06176blu","article-title":"Comorbidity patterns of anxiety and depressive disorders in a large cohort study: the Netherlands Study of Depression and Anxiety (NESDA)","volume":"72","author":"Lamers","year":"2011","journal-title":"J. Clin. Psychiatry."},{"key":"10.1016\/j.jad.2020.01.032_bib0044","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1097\/MLR.0b013e318160d093","article-title":"Validation and standardization of the generalized anxiety disorder screener (GAD-7) in the general population","volume":"46","author":"L\u00f6we","year":"2008","journal-title":"Med. Care."},{"key":"10.1016\/j.jad.2020.01.032_bib0042","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0165-0327(03)00198-8","article-title":"Measuring depression outcome with a brief self-report instrument: sensitivity to change of the Patient Health Questionnaire (PHQ-9)","volume":"81","author":"L\u00f6we","year":"2004","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2020.01.032_bib0045","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.genhosppsych.2008.01.001","article-title":"Depression, anxiety and somatization in primary care: syndrome overlap and functional impairment","volume":"30","author":"L\u00f6we","year":"2008","journal-title":"Gen. Hosp. Psychiatry."},{"key":"10.1016\/j.jad.2020.01.032_bib0043","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1097\/00005650-200412000-00006","article-title":"Monitoring depression treatment outcomes with the patient health questionnaire-9","volume":"42","author":"L\u00f6we","year":"2004","journal-title":"Med. Care."},{"key":"10.1016\/j.jad.2020.01.032_bib0046","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/0165-0327(88)90072-9","article-title":"The Hamilton Anxiety Scale: reliability, validity, and sensitivity to change in anxiety and depressive disorders","volume":"14","author":"Maier","year":"1988","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2020.01.032_bib0055","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1002\/mpr.353","article-title":"Assessing anxious features in depressed outpatients","volume":"20","author":"McClintock","year":"2011","journal-title":"Int. J. Methods Psychiatr. Res."},{"key":"10.1016\/j.jad.2020.01.032_bib0047","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1001\/jama.1994.03520220035028","article-title":"Common mental disorders and disability across cultures. Results from the who collaborative study on psychological problems in general health care","volume":"272","author":"Ormel","year":"1994","journal-title":"JAMA."},{"key":"10.1016\/j.jad.2020.01.032_bib0048","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1176\/appi.ajp.162.6.1171","article-title":"Quality-of-life impairment in depressive and anxiety disorders","volume":"162","author":"Rapaport","year":"2005","journal-title":"Am. J. Psychiatry."},{"key":"10.1016\/j.jad.2020.01.032_bib0049","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.jad.2011.03.024","article-title":"Implementation of psychological tehrapies for anxiety and depression in routine practice: two year prospective cohort study","volume":"133","author":"Richards","year":"2011","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2020.01.032_bib0050","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1192\/S0007125000298395","article-title":"Depression comorbid with anxiety: results from the WHO study on psychological disorders in primary health care","volume":"38","author":"Sartorius","year":"1996","journal-title":"Br. J. Psychiatry Suppl."},{"key":"10.1016\/j.jad.2020.01.032_bib0051","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.janxdis.2013.11.006","article-title":"Establishing a common metric for self-reported anxiety: linking the MASQ, PANAS, and GAD-7 to Promis Anxiety","volume":"28","author":"Schalet","year":"2014","journal-title":"J. Anxiety Disord."},{"key":"10.1016\/j.jad.2020.01.032_bib0052","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1001\/jamapsychiatry.2016.3880","article-title":"Effect of disorder-specific vs nonspecific psychotherapy for chronic depression a randomized clinical trial","volume":"74","author":"Schramm","year":"2017","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.jad.2020.01.032_bib0053","first-page":"125","volume":"9","author":"Schuck","year":"2000","journal-title":"Z. Med. Psychol"},{"key":"10.1016\/j.jad.2020.01.032_bib0058","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1001\/jama.1995.03530190025030","article-title":"Health-related quality of life in primary care patients with mental disorders. Results from the prime-md 1000 study","volume":"274","author":"Spitzer","year":"1995","journal-title":"JAMA"},{"key":"10.1016\/j.jad.2020.01.032_bib0059","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1001\/jama.282.18.1737","article-title":"Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study","volume":"282","author":"Spitzer","year":"1999","journal-title":"JAMA."},{"key":"10.1016\/j.jad.2020.01.032_bib0060","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1001\/archinte.166.10.1092","article-title":"A brief measure for assessing generalized anxiety disorder\u2014The GAD-7","volume":"166","author":"Spitzer","year":"2006","journal-title":"Arch. Intern. Med."},{"key":"10.1016\/j.jad.2020.01.032_bib0054","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0005-7967(93)E0028-4","article-title":"Pathological worry in major depression: a preliminary report","volume":"33","author":"Starcevic","year":"1995","journal-title":"Behav. Res. Ther."},{"key":"10.1016\/j.jad.2020.01.032_bib0056","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1007\/s11136-011-0054-x","article-title":"Implementing patient-reported outcomes assessment in clinical practice: a review of the options and considerations","volume":"21","author":"Snyder","year":"2012","journal-title":"Qual. Life Res."},{"key":"10.1016\/j.jad.2020.01.032_bib0057","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1097\/MLR.0b013e31829b1d84","article-title":"Patient-reported outcomes (PROs): putting the patient perspective in patient-centered outcomes research","volume":"51","author":"Snyder","year":"2013","journal-title":"Med. Care."},{"key":"10.1016\/j.jad.2020.01.032_bib0061","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1136\/ebm.11.6.184","article-title":"The GAD-7 scale was accurate for diagnosing generalized anxiety disorder","volume":"11","author":"Swinson","year":"2006","journal-title":"Evid. Based Med."},{"key":"10.1016\/j.jad.2020.01.032_bib0063","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.euroneuro.2011.07.018","article-title":"The size and burden of mental disorders and other disorders of the brain in Europe 2010","volume":"21","author":"Wittchen","year":"2011","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.jad.2020.01.032_bib0062","first-page":"24","article-title":"Generalized anxiety and depression in primary care: prevalence, recognition, and management","volume":"63","author":"Wittchen","year":"2002","journal-title":"J. Clin. Psychiatry."},{"key":"10.1016\/j.jad.2020.01.032_bib0064","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1179\/2042618612Y.0000000001","article-title":"Clinimetrics corner: a closer look at the minimal clinically important difference (MCID)","volume":"20","author":"Wright","year":"2012","journal-title":"J. Man. Manip. Ther."},{"key":"10.1016\/j.jad.2020.01.032_bib0065","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.jclinepi.2013.04.005","article-title":"Measure once, cut twice-adding patient reported outcome measures to the electronic health record for comparative effectiveness research","volume":"8","author":"Wu","year":"2013","journal-title":"J. Clin. Epidemiol."},{"key":"10.1016\/j.jad.2020.01.032_bib0066","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/S0895-4356(99)00071-2","article-title":"Further evidence supporting an SEM-based criterion for identifying meaningful intra-individual changes in health-related quality of life","volume":"52","author":"Wyrwich","year":"1999","journal-title":"J. Clin. Epidemiol."}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032719313643?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032719313643?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T01:39:34Z","timestamp":1759023574000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165032719313643"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3]]},"references-count":66,"alternative-id":["S0165032719313643"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2020.01.032","relation":{},"ISSN":["0165-0327"],"issn-type":[{"value":"0165-0327","type":"print"}],"subject":[],"published":{"date-parts":[[2020,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sensitivity to change and minimal clinically important difference of the 7-item Generalized Anxiety Disorder Questionnaire (GAD-7)","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2020.01.032","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}