{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T13:23:47Z","timestamp":1793021027089,"version":"4.5.0"},"reference-count":49,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004954","name":"Augustinus Fonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004954","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008218","name":"Gangstedfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008218","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003554","name":"Lundbeckfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003554","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012774","name":"Innovationsfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012774","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008391","name":"Markedsmodningsfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008391","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008392","name":"Sundhed og Sygdom, Det Frie Forskningsr\u00e5d","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008392","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005860","name":"Helsefonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005860","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2020,6]]},"DOI":"10.1016\/j.jad.2020.03.049","type":"journal-article","created":{"date-parts":[[2020,3,27]],"date-time":"2020-03-27T02:52:53Z","timestamp":1585277573000},"page":"336-344","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":49,"special_numbering":"C","title":["Mood instability in patients with newly diagnosed bipolar disorder, unaffected relatives, and healthy control individuals measured daily using smartphones"],"prefix":"10.1016","volume":"271","author":[{"given":"Sharleny","family":"Stanislaus","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Faurholt-Jepsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maj","family":"Vinberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klara","family":"Coello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanne Lie","family":"Kj\u00e6rstad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sigurd","family":"Melbye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimie S.O.","family":"Sletved","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen Margrethe","family":"Christensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mads","family":"Frost","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakob E.","family":"Bardram","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars Vedel","family":"Kessing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jad.2020.03.049_bib0001","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1111\/j.1537-2995.2010.02867.x","article-title":"Cardiovascular and demographic characteristics in whole blood and plasma donors: results from the donor insight study","volume":"51","author":"Atsma","year":"2011","journal-title":"Transfusion"},{"key":"10.1016\/j.jad.2020.03.049_bib0002","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1111\/j.1399-5618.2007.00385.x","article-title":"Effects of treatment latency on response to maintenance treatment in manic-depressive disorders","volume":"9","author":"Baldessarini","year":"2007","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.jad.2020.03.049_bib0003","doi-asserted-by":"crossref","unstructured":"Bardram, Jakob E, Mads Frost, K\u00e1roly Sz\u00e1nt\u00f3, Maria Faurholt-Jepsen, Maj Vinberg, and Lars Vedel Kessing. 2013. Designing mobile health technology for bipolar disorder: a field trial of the monarca system. In Proceedings of the SIGCHI Conference on Human Factors in Computing Systems, 2627\u201336. ACM.","DOI":"10.1145\/2470654.2481364"},{"key":"10.1016\/j.jad.2020.03.049_bib0004","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1046\/j.1399-5618.2003.00085.x","article-title":"Using technology to improve longitudinal studies: self-reporting with chronorecord in bipolar disorder","volume":"6","author":"Bauer","year":"2004","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.jad.2020.03.049_bib0005","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1111\/bdi.12060","article-title":"Mood lability among offspring of parents with bipolar disorder and community controls","volume":"15","author":"Birmaher","year":"2013","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.jad.2020.03.049_bib0006","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.jad.2018.07.045","article-title":"Thresholds for severity, remission and recovery using the functioning assessment short test (FAST) in bipolar disorder","volume":"240","author":"Bonnin","year":"2018","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2020.03.049_bib0007","first-page":"916","article-title":"Nonlinear time-series approaches in characterizing mood stability and mood instability in bipolar disorder","volume":"279","author":"Bonsall","year":"2012","journal-title":"Proc. Biol. Sci."},{"key":"10.1016\/j.jad.2020.03.049_bib0008","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1192\/bjp.bp.114.158543","article-title":"Mood instability: significance, definition and measurement","volume":"207","author":"Broome","year":"2015","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.jad.2020.03.049_bib0009","series-title":"'Statistical Power Analysis For the Social Sciences (2nd)","author":"Cohen","year":"1988"},{"key":"10.1016\/j.jad.2020.03.049_bib0010","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1111\/bdi.12194","article-title":"Type and duration of subsyndromal symptoms in youth with bipolar i disorder prior to their first manic episode","volume":"16","author":"Correll","year":"2014","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.jad.2020.03.049_bib0011","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1177\/0706743716656607","article-title":"Meta-analysis of the interval between the onset and management of bipolar disorder","volume":"62","author":"Dagani","year":"2017","journal-title":"Can. J. Psychiatry"},{"issue":"2","key":"10.1016\/j.jad.2020.03.049_bib0012","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/bdi.12721","article-title":"Daily and weekly mood ratings using a remote capture method in high-risk offspring of bipolar parents: compliance and symptom monitoring","volume":"21","author":"Duffy","year":"2019","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.jad.2020.03.049_bib0013","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1037\/a0017075","article-title":"Ecological momentary assessment of mood disorders and mood dysregulation","volume":"21","author":"Ebner-Priemer","year":"2009","journal-title":"Psychol. Assess."},{"issue":"7","key":"10.1016\/j.jad.2020.03.049_bib0015","doi-asserted-by":"crossref","first-page":"0","DOI":"10.1111\/bdi.12796","article-title":"Is smartphone-based mood instability associated with stress, quality of life, and functioning in bipolar disorder?","volume":"21","author":"Faurholt-Jepsen","year":"2019","journal-title":"Bipolar Disord."},{"issue":"162","key":"10.1016\/j.jad.2020.03.049_bib49","article-title":"Reporting guidelines on remotely collected electronic mood data in mood disorder (eMOOD)-recommondations","volume":"9","author":"Faurholt-Jepsen","year":"2019","journal-title":"Translational psychiatry"},{"key":"10.1016\/j.jad.2020.03.049_bib0014","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s40345-019-0141-4","article-title":"Differences in mood instability in patients with bipolar disorder type I and II: a smartphone-based study","volume":"7","author":"Faurholt-Jepsen","year":"2019","journal-title":"Int. J. Bipolar Disord."},{"key":"10.1016\/j.jad.2020.03.049_bib0016","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.jad.2015.06.026","article-title":"Mood instability in bipolar disorder type i versus type II-continuous daily electronic self-monitoring of illness activity using smartphones","volume":"186","author":"Faurholt-Jepsen","year":"2015","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2020.03.049_bib0017","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1093\/ije\/dyt095","article-title":"Differences between blood donors and a population sample: implications for case-control studies","volume":"42","author":"Golding","year":"2013","journal-title":"Int. J. Epidemiol."},{"key":"10.1016\/j.jad.2020.03.049_bib0018","unstructured":"Goodwin, F.K., Jamison, K.R.2007. Manic-Depressive Illness (2007)."},{"key":"10.1016\/j.jad.2020.03.049_bib0019","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1176\/appi.ajp.2015.15040414","article-title":"Toward the definition of a bipolar prodrome: dimensional predictors of bipolar spectrum disorders in at-risk youths","volume":"173","author":"Hafeman","year":"2016","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.jad.2020.03.049_bib0020","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1001\/jamapsychiatry.2017.1763","article-title":"Assessment of a person-level risk calculator to predict new-onset bipolar spectrum disorder in youth at familial risk","volume":"74","author":"Hafeman","year":"2017","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.jad.2020.03.049_bib0021","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1111\/j.2044-8260.1967.tb00530.x","article-title":"Development of a rating scale for primary depressive illness","volume":"6","author":"Hamilton","year":"1967","journal-title":"Br. J. Clin. Psychol."},{"key":"10.1016\/j.jad.2020.03.049_bib0022","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.tins.2017.10.006","article-title":"The emerging neurobiology of bipolar disorder","volume":"41","author":"Harrison","year":"2018","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.jad.2020.03.049_bib0023","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.eurpsy.2006.08.003","article-title":"Early recognition of bipolar disorder","volume":"22","author":"Hauser","year":"2007","journal-title":"Eur. Psychiatry"},{"key":"10.1016\/j.jad.2020.03.049_bib0024","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.psychres.2005.11.016","article-title":"Affective lability and affect intensity as core dimensions of bipolar disorders during euthymic period","volume":"159","author":"Henry","year":"2008","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.jad.2020.03.049_bib0025","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1046\/j.1399-5618.2003.00091.x","article-title":"A prospective, longitudinal study of percentage of time spent ill in patients with bipolar I or bipolar II disorders","volume":"6","author":"Joffe","year":"2004","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.jad.2020.03.049_bib0026","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1111\/acps.12667","article-title":"Evidence for clinical progression of unipolar and bipolar disorders","volume":"135","author":"Kessing","year":"2017","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.jad.2020.03.049_bib0027","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2016-015462","article-title":"The bipolar illness onset study: research protocol for the bio cohort study","volume":"7","author":"Kessing","year":"2017","journal-title":"BMJ Open"},{"key":"10.1016\/j.jad.2020.03.049_bib0028","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1192\/bjp.bp.112.113548","article-title":"Treatment in a specialised out-patient mood disorder clinic v. standard out-patient treatment in the early course of bipolar disorder: randomised clinical trial","volume":"202","author":"Kessing","year":"2013","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.jad.2020.03.049_bib0029","first-page":"168","article-title":"Lifetime prevalence and age-of-onset distributions of mental disorders in the world health organization's world mental health survey initiative","volume":"6","author":"Kessler","year":"2007","journal-title":"World Psychiatry"},{"key":"10.1016\/j.jad.2020.03.049_bib0030","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.jad.2009.10.019","article-title":"A randomized comparison of online and paper mood charts for people with bipolar disorder","volume":"124","author":"Lieberman","year":"2010","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2020.03.049_bib0031","series-title":"Genetics of Bipolar disorder: Clinical and Neurobiological Foundations","author":"Lohoff","year":"2010"},{"key":"10.1016\/j.jad.2020.03.049_bib0032","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1034\/j.1399-5618.2003.00048.x","article-title":"Subsyndromal symptoms assessed in longitudinal, prospective follow-up of a cohort of patients with bipolar disorder","volume":"5","author":"MacQueen","year":"2003","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.jad.2020.03.049_bib0033","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1017\/S0033291713002407","article-title":"How is affective instability defined and measured? A systematic review","volume":"44","author":"Marwaha","year":"2014","journal-title":"Psychol. Med."},{"key":"10.1016\/j.jad.2020.03.049_bib0034","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.jad.2017.07.029","article-title":"Longitudinal mood monitoring in bipolar disorder: course of illness as revealed through a short messaging service","volume":"223","author":"McKnight","year":"2017","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2020.03.049_bib0035","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.jad.2018.04.021","article-title":"Mood instability as a predictor of clinical and functional outcomes in adolescents with bipolar I and bipolar II disorder","volume":"236","author":"O'Donnell","year":"2018","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2020.03.049_bib0036","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2014-007504","article-title":"Mood instability is a common feature of mental health disorders and is associated with poor clinical outcomes","volume":"5","author":"Patel","year":"2015","journal-title":"BMJ Open"},{"key":"10.1016\/j.jad.2020.03.049_bib0037","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.jpsychires.2004.05.006","article-title":"Sex-specific self-reported mood changes by patients with bipolar disorder","volume":"39","author":"Rasgon","year":"2005","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.jad.2020.03.049_bib0038","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/1745-0179-3-5","article-title":"Validity and reliability of the functioning assessment short test (FAST) in bipolar disorder","volume":"3","author":"Rosa","year":"2007","journal-title":"Clin. Pract. Epidemiol. Mental Health"},{"key":"10.1016\/j.jad.2020.03.049_bib0039","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1111\/j.1399-5618.2007.00490.x","article-title":"Effectiveness of mood stabilizers and antipsychotics in the maintenance phase of bipolar disorder: a systematic review of randomized controlled trials","volume":"9","author":"Smith","year":"2007","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.jad.2020.03.049_bib0040","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1192\/bjp.bp.114.162073","article-title":"Affective instability and the course of bipolar depression: results from the step-BD randomised controlled trial of psychosocial treatment","volume":"208","author":"Stange","year":"2016","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.jad.2020.03.049_bib0041","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/S0197-2456(02)00320-3","article-title":"Patient compliance with paper and electronic diaries","volume":"24","author":"Stone","year":"2003","journal-title":"Control. Clin. Trials"},{"key":"10.1016\/j.jad.2020.03.049_bib0042","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1111\/acps.12065","article-title":"Mood instability and functional recovery in bipolar disorders","volume":"128","author":"Strejilevich","year":"2013","journal-title":"Acta Psychiatr. Scand."},{"issue":"7","key":"10.1016\/j.jad.2020.03.049_bib0043","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1002\/gps.5094","article-title":"Episodic density, subsyndromic symptoms and mood instability in late-life bipolar disorders: a 5-year follow-up study","volume":"34","author":"Strejilevich","year":"2019","journal-title":"Int. J. Geriatr. Psychiatry"},{"key":"10.1016\/j.jad.2020.03.049_bib0044","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.jad.2016.06.065","article-title":"Daily longitudinal self-monitoring of mood variability in bipolar disorder and borderline personality disorder","volume":"205","author":"Tsanas","year":"2016","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2020.03.049_bib0045","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.jaac.2016.04.017","article-title":"The bipolar prodrome: meta-analysis of symptom prevalence prior to initial or recurrent mood episodes","volume":"55","author":"Van Meter","year":"2016","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"key":"10.1016\/j.jad.2020.03.049_bib0046","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1038\/s41398-017-0012-7","article-title":"Genome-wide analysis in UK biobank identifies four loci associated with mood instability and genetic correlation with major depressive disorder, anxiety disorder and schizophrenia","volume":"7","author":"Ward","year":"2017","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.jad.2020.03.049_bib0047","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1001\/archpsyc.1990.01810180089012","article-title":"Schedules fonr clinical assessment in neuropsychiatry","volume":"47","author":"Wing","year":"1990","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.jad.2020.03.049_bib0048","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1192\/bjp.133.5.429","article-title":"A rating scale for mania: reliability, validity and sensitivity","volume":"133","author":"Young","year":"1978","journal-title":"Br. J. Psychiatry"}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032719320348?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032719320348?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T01:42:54Z","timestamp":1759023774000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165032719320348"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6]]},"references-count":49,"alternative-id":["S0165032719320348"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2020.03.049","relation":{},"ISSN":["0165-0327"],"issn-type":[{"value":"0165-0327","type":"print"}],"subject":[],"published":{"date-parts":[[2020,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mood instability in patients with newly diagnosed bipolar disorder, unaffected relatives, and healthy control individuals measured daily using smartphones","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2020.03.049","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}