{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:57:09Z","timestamp":1790211429158,"version":"4.1.0"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100011912","name":"Taipei Veterans General Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011912","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1016\/j.jad.2020.10.056","type":"journal-article","created":{"date-parts":[[2020,10,28]],"date-time":"2020-10-28T22:26:57Z","timestamp":1603924017000},"page":"687-691","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Bidirectional association between migraine and depression among probands and unaffected siblings: A nationwide population-based study"],"prefix":"10.1016","volume":"279","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6516-1073","authenticated-orcid":false,"given":"Mu-Hong","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tai-Long","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Chen","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai-Lin","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ju-Wei","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng-Ta","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih-Jen","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tung-Ping","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8350-0232","authenticated-orcid":false,"given":"Tzeng-Ji","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya-Mei","family":"Bai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jad.2020.10.056_bib0001","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1016\/S0140-6736(18)32279-7","article-title":"Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017","volume":"392","author":"Disease","year":"2018","journal-title":"Lancet"},{"key":"10.1016\/j.jad.2020.10.056_bib0002","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1111\/j.1526-4610.2011.02036.x","article-title":"A population-based longitudinal community study of major depression and migraine","volume":"52","author":"Modgill","year":"2012","journal-title":"Headache"},{"key":"10.1016\/j.jad.2020.10.056_bib0003","first-page":"387","article-title":"Joint 1994 Wolff Award Presentation","volume":"34","author":"Breslau","year":"1994","journal-title":"Migraine and major depression: a longitudinal study. Headache."},{"key":"10.1016\/j.jad.2020.10.056_bib0004","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1038\/s41431-018-0150-2","article-title":"International Headache Genetics C, van den Maagdenberg A, Terwindt GM, Nyholt DR. Molecular genetic overlap between migraine and major depressive disorder","volume":"26","author":"Yang","year":"2018","journal-title":"Eur J Hum Genet"},{"key":"10.1016\/j.jad.2020.10.056_bib0005","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1017\/thg.2016.46","article-title":"Shared Genetic Factors Underlie Migraine and Depression","volume":"19","author":"Yang","year":"2016","journal-title":"Twin Res Hum Genet"},{"key":"10.1016\/j.jad.2020.10.056_bib0006","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1007\/BF03401725","article-title":"Comorbid migraine with aura, anxiety, and depression is associated with dopamine D2 receptor (DRD2) NcoI alleles","volume":"4","author":"Peroutka","year":"1998","journal-title":"Mol Med"},{"key":"10.1016\/j.jad.2020.10.056_bib0007","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1017\/thg.2016.43","article-title":"Familial Aggregation of Migraine and Depression: Insights From a Large Australian Twin Sample","volume":"19","author":"Yang","year":"2016","journal-title":"Twin Res Hum Genet"},{"key":"10.1016\/j.jad.2020.10.056_bib0008","doi-asserted-by":"crossref","first-page":"2397","DOI":"10.1017\/S003329171800332X","article-title":"Risk and coaggregation of major psychiatric disorders among first-degree relatives of patients with bipolar disorder: a nationwide population-based study","volume":"49","author":"Chen","year":"2019","journal-title":"Psychol Med"},{"key":"10.1016\/j.jad.2020.10.056_bib0009","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1038\/mp.2017.217","article-title":"Co-aggregation of major psychiatric disorders in individuals with first-degree relatives with schizophrenia: a nationwide population-based study","volume":"23","author":"Cheng","year":"2018","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.jad.2020.10.056_bib0010","doi-asserted-by":"crossref","first-page":"788","DOI":"10.2337\/dc15-1807","article-title":"Risk of Developing Type 2 Diabetes in Adolescents and Young Adults With Autism Spectrum Disorder: A Nationwide Longitudinal Study","volume":"39","author":"Chen","year":"2016","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jad.2020.10.056_bib0011","first-page":"1","article-title":"Familial coaggregation of major psychiatric disorders among first-degree relatives of patients with obsessive-compulsive disorder: a nationwide study","author":"Huang","year":"2020","journal-title":"Psychol Med"},{"key":"10.1016\/j.jad.2020.10.056_bib0012","first-page":"1","article-title":"Incorporating development stratification of Taiwan townships into sampling design of large scale health interview survey","volume":"4","author":"Liu","year":"2006","journal-title":"J Health Management (Chin)"},{"key":"10.1016\/j.jad.2020.10.056_bib0013","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0021-9681(87)90171-8","article-title":"A new method of classifying prognostic comorbidity in longitudinal studies: development and validation","volume":"40","author":"Charlson","year":"1987","journal-title":"J Chronic Dis"},{"key":"10.1016\/j.jad.2020.10.056_bib0014","article-title":"Affective spectrum disorders in an urban Swedish adult psychiatric unit: a descriptive study","volume":"2012","author":"Scharin","year":"2012","journal-title":"Depress Res Treat"},{"key":"10.1016\/j.jad.2020.10.056_bib0015","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s12017-012-8195-9","article-title":"Identification of a novel ANKK1 and other dopaminergic (DRD2 and DBH) gene variants in migraine susceptibility","volume":"15","author":"Ghosh","year":"2013","journal-title":"Neuromolecular Med"},{"key":"10.1016\/j.jad.2020.10.056_bib0016","doi-asserted-by":"crossref","first-page":"4505","DOI":"10.1111\/jcmm.14390","article-title":"The exploration of mechanisms of comorbidity between migraine and depression","volume":"23","author":"Zhang","year":"2019","journal-title":"J Cell Mol Med"},{"key":"10.1016\/j.jad.2020.10.056_bib0017","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s00439-013-1370-8","article-title":"Genetic risk score analysis indicates migraine with and without comorbid depression are genetically different disorders","volume":"133","author":"Ligthart","year":"2014","journal-title":"Hum Genet"},{"key":"10.1016\/j.jad.2020.10.056_bib0018","first-page":"37","article-title":"Why are migraineurs more depressed? A review of the factors contributing to the comorbidity of migraine and depression","volume":"19","author":"Baksa","year":"2017","journal-title":"Neuropsychopharmacol Hung"},{"key":"10.1016\/j.jad.2020.10.056_bib0019","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1097\/WCO.0b013e328352c416","article-title":"Depression in headaches: chronification","volume":"25","author":"Deligianni","year":"2012","journal-title":"Curr Opin Neurol"},{"key":"10.1016\/j.jad.2020.10.056_bib0020","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1177\/0333102416638520","article-title":"Genetic epidemiology of migraine and depression","volume":"36","author":"Yang","year":"2016","journal-title":"Cephalalgia"},{"key":"10.1016\/j.jad.2020.10.056_bib0021","doi-asserted-by":"crossref","first-page":"3905","DOI":"10.2174\/1381612824666181112112309","article-title":"Brain Peptides for the Treatment of Neuropsychiatric Disorders","volume":"24","author":"Karatas","year":"2018","journal-title":"Curr Pharm Des"},{"key":"10.1016\/j.jad.2020.10.056_bib0022","first-page":"83","article-title":"European Headache Federation School of Advanced S","volume":"19","author":"Amin","year":"2018","journal-title":"The association between migraine and physical exercise. J Headache Pain."},{"key":"10.1016\/j.jad.2020.10.056_bib0023","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/j.jagp.2020.02.001","article-title":"Depression and Cognitive Dysfunction in Older U.S. Military Veterans: Moderating Effects of BDNF Val66Met Polymorphism and Physical Exercise","volume":"28","author":"Pitts","year":"2020","journal-title":"Am J Geriatr Psychiatry"},{"key":"10.1016\/j.jad.2020.10.056_bib0024","doi-asserted-by":"crossref","first-page":"2528","DOI":"10.1111\/jcmm.13418","article-title":"Effect of caloric restriction on depression","volume":"22","author":"Manchishi","year":"2018","journal-title":"J Cell Mol Med"},{"key":"10.1016\/j.jad.2020.10.056_bib0025","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1007\/s12020-008-9090-x","article-title":"Evaluation of the effect of caloric restriction on serum BDNF in overweight and obese subjects: preliminary evidences","volume":"33","author":"Araya","year":"2008","journal-title":"Endocrine"},{"key":"10.1016\/j.jad.2020.10.056_bib0026","first-page":"11","article-title":"A Randomized Double-Blind, Cross-Over Trial of very Low-Calorie Diet in Overweight Migraine Patients: A Possible Role for Ketones?","author":"Di Lorenzo","year":"2019","journal-title":"Nutrients"}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032720329001?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032720329001?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T01:50:13Z","timestamp":1759024213000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165032720329001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":26,"alternative-id":["S0165032720329001"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2020.10.056","relation":{},"ISSN":["0165-0327"],"issn-type":[{"value":"0165-0327","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bidirectional association between migraine and depression among probands and unaffected siblings: A nationwide population-based study","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2020.10.056","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}