{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T14:41:52Z","timestamp":1784212912935,"version":"3.55.0"},"reference-count":71,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1016\/j.jad.2020.11.035","type":"journal-article","created":{"date-parts":[[2020,11,10]],"date-time":"2020-11-10T21:36:19Z","timestamp":1605044179000},"page":"908-917","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Do increases in deep grey matter volumes after electroconvulsive therapy persist in patients with major depression? A longitudinal MRI-study"],"prefix":"10.1016","volume":"281","author":[{"given":"Margit","family":"Jehna","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter","family":"Wurm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Pinter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrin","family":"Vogel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1622-4055","authenticated-orcid":false,"given":"Anna","family":"Holl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Hofmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Ebner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Ropele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8544-035X","authenticated-orcid":false,"given":"Gottfried","family":"Fuchs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans-Peter","family":"Kapfhammer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannes","family":"Deutschmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Enzinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jad.2020.11.035_bib0001","doi-asserted-by":"crossref","first-page":"e483","DOI":"10.1038\/tp.2014.124","article-title":"Hippocampal structural and functional changes associated with electroconvulsive therapy response.","volume":"4","author":"Abbott","year":"2014","journal-title":"Transl. Psychiatry"},{"issue":"6","key":"10.1016\/j.jad.2020.11.035_bib0002","article-title":"Lifetime major depression and grey-matter volume","volume":"43","author":"Ancelin","year":"2018","journal-title":"J Psychiatry Neurosci"},{"key":"10.1016\/j.jad.2020.11.035_bib0004","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1002\/hbm.23108","article-title":"Computational meta-analysis of statistical parametric maps in major depression","volume":"37","author":"Arnone","year":"2016","journal-title":"Hum. Brain Mapp."},{"issue":"2","key":"10.1016\/j.jad.2020.11.035_bib0005","doi-asserted-by":"crossref","first-page":"76","DOI":"10.3109\/15622975.2014.1001786","article-title":"World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Unipolar Depressive Disorders. Part 2: Maintenance Treatment of Major Depressive Disorder-Update","volume":"16","author":"Bauer","year":"2015","journal-title":"World J Biol Psychiatry"},{"issue":"Pt 4","key":"10.1016\/j.jad.2020.11.035_bib0007","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1093\/brain\/awp028","article-title":"Cortical and subcortical networks in human secondarily generalized tonic-clonic seizures","volume":"132","author":"Blumenfeld","year":"2009","journal-title":"Brain"},{"key":"10.1016\/j.jad.2020.11.035_bib0006","doi-asserted-by":"crossref","first-page":"1556","DOI":"10.1016\/S1053-8119(03)00204-0","article-title":"Selective frontal, parietal, and temporal networks in generalized seizures","volume":"19","author":"Blumenfeld","year":"2003","journal-title":"Neuroimage"},{"key":"10.1016\/j.jad.2020.11.035_bib0008","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/j.1365-2362.1977.tb01578.x","article-title":"The permeability of the blood\u2014brain barrier during electrically induced seizures in man [Internet]","volume":"7","author":"Bolwig","year":"1977","journal-title":"Eur. J. Clin. Invest."},{"issue":"433","key":"10.1016\/j.jad.2020.11.035_bib0009","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1111\/j.1600-0447.2007.00971.x","article-title":"Electroconvulsive therapy in melancholia: the role of hippocampal neurogenesis","author":"Bolwig","year":"2007","journal-title":"Acta Psychiatr Scand Suppl"},{"issue":"11","key":"10.1016\/j.jad.2020.11.035_bib0012","doi-asserted-by":"crossref","first-page":"2741","DOI":"10.1038\/npp.2016.86","article-title":"Relationship Between Hippocampal Volume, Serum BDNF, and Depression Severity Following Electroconvulsive Therapy in Late-Life Depression","volume":"41","author":"Bouckaert","year":"2016","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.jad.2020.11.035_bib0010","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1097\/YCT.0000000000000129","article-title":"ECT: Its brain enabling effects: A review of electroconvulsive therapy-induced structural brain plasticity","volume":"30","author":"Bouckaert","year":"2014","journal-title":"J. ECT"},{"key":"10.1016\/j.jad.2020.11.035_bib0011","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1503\/jpn.140322","article-title":"Grey matter volume increase following electroconvulsive therapy in patients with late life depression: a longitudinal MRI study","volume":"41","author":"Bouckaert","year":"2016","journal-title":"J. Psychiatry Neurosci."},{"key":"10.1016\/j.jad.2020.11.035_bib0013","article-title":"Electroconvulsive therapy modulates grey matter increase in a hub of an affect processing network","volume":"25","author":"Camilleri","year":"2019","journal-title":"Neuroimage Clin"},{"key":"10.1016\/j.jad.2020.11.035_bib0014","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1139\/jpn.0441","article-title":"The role of the hippocampus in the pathophysiology of major depression","volume":"29","author":"Campbell","year":"2004","journal-title":"J. Psychiatry Neurosci."},{"key":"10.1016\/j.jad.2020.11.035_bib0015","doi-asserted-by":"crossref","first-page":"e1023","DOI":"10.1038\/tp.2016.267","article-title":"Brain volumetric and metabolic correlates of electroconvulsive therapy for treatment-resistant depression: A longitudinal neuroimaging study","volume":"7","author":"Cano","year":"2017","journal-title":"Transl. Psychiatry"},{"issue":"1","key":"10.1016\/j.jad.2020.11.035_bib0016","doi-asserted-by":"crossref","first-page":"5434","DOI":"10.1038\/s41598-018-23685-9","article-title":"Predicting individual responses to the electroconvulsive therapy with hippocampal subfield volumes in major depression disorder","volume":"8","author":"Cao","year":"2018","journal-title":"Sci Rep"},{"issue":"5","key":"10.1016\/j.jad.2020.11.035_bib0017","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.euroneuro.2008.12.007","article-title":"Repeated electroconvulsive seizures increase the total number of synapses in adult male rat hippocampus","volume":"19","author":"Chen","year":"2009","journal-title":"Eur Neuropsychopharmacol"},{"key":"10.1016\/j.jad.2020.11.035_bib0018","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1176\/ajp.145.6.701","article-title":"Effects of ECT on brain structure: a pilot prospective magnetic resonance imaging study","volume":"145","author":"Coffey","year":"1988","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.jad.2020.11.035_bib0019","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.ajp.2017.01.025","article-title":"The neurobiology of depression: An integrated view","volume":"27","author":"Dean","year":"2017","journal-title":"Asian J Psychiatr"},{"key":"10.1016\/j.jad.2020.11.035_bib0020","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1073\/pnas.1321399111","article-title":"Electroconvulsive therapy-induced brain plasticity determines therapeutic outcome in mood disorders","volume":"111","author":"Dukart","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.jad.2020.11.035_bib0022","first-page":"26","article-title":"Brain magnetic resonance imaging in elderly depressed patients receiving electroconvulsive therapy","volume":"5","author":"Figiel","year":"1989","journal-title":"Convuls. Ther."},{"key":"10.1016\/j.jad.2020.11.035_bib0023","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"\u201cMini-mental state\u201d: A practical method for grading the cognitive state of patients for the clinician","volume":"12","author":"Folstein","year":"1975","journal-title":"J. Psychiatr. Res."},{"issue":"3","key":"10.1016\/j.jad.2020.11.035_bib0024","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1111\/acps.12884","article-title":"Electroconvulsive therapy increases brain volume in major depression: a systematic review and meta\u2010analysis","volume":"138","author":"Gbyl","year":"2018","journal-title":"Acta Psychiatr Scand"},{"issue":"3","key":"10.1016\/j.jad.2020.11.035_bib0025","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1192\/bjp.2018.224","article-title":"Structural changes in amygdala nuclei, hippocampal subfields and cortical thickness following electroconvulsive therapy in treatment-resistant depression: longitudinal analysis","volume":"214","author":"Gryglewski","year":"2019","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.jad.2020.11.035_bib0026","series-title":"Beck depressions-inventar (BDI-II)","year":"2006"},{"key":"10.1016\/j.jad.2020.11.035_bib72","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1176\/appi.ajp.159.2.331","article-title":"The Practice of Electroconvulsive Therapy: Recommendations for Treatment, Training, and Privileging: A Task Force Report of the American Psychiatric Association","volume":"159","author":"Jaffe","year":"2002","journal-title":"Am. J. Psychiatry"},{"issue":"2","key":"10.1016\/j.jad.2020.11.035_bib0027","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1111\/acps.12462","article-title":"Regional brain volumes, diffusivity, and metabolite changes after electroconvulsive therapy for severe depression","volume":"133","author":"Jorgensen","year":"2016","journal-title":"Acta Psychiatr Scand"},{"key":"10.1016\/j.jad.2020.11.035_bib0028","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.biopsych.2015.02.029","article-title":"Structural plasticity of the hippocampus and amygdala induced by electroconvulsive therapy in major depression","volume":"79","author":"Joshi","year":"2016","journal-title":"Biol. Psychiatry"},{"issue":"2","key":"10.1016\/j.jad.2020.11.035_bib0029","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.mehy.2012.04.036","article-title":"Appropriateness for electroconvulsive therapy (ECT) can be assessed on a three-item scale","volume":"79","author":"Kellner","year":"2012","journal-title":"Med Hypotheses"},{"key":"10.1016\/j.jad.2020.11.035_bib0030","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1016\/j.neuroimage.2011.06.080","article-title":"A comprehensive testing protocol for MRI neuroanatomical segmentation techniques: Evaluation of a novel lateral ventricle segmentation method","volume":"58","author":"Kempton","year":"2011","journal-title":"Neuroimage"},{"key":"10.1016\/j.jad.2020.11.035_bib0031","doi-asserted-by":"crossref","first-page":"195","DOI":"10.4103\/0019-5545.37321","article-title":"MRI T 2 relaxometry of brain regions and cognitive dysfunction following electroconvulsive therapy","volume":"49","author":"Kunigiri","year":"2007","journal-title":"Indian J. Psychiatry"},{"key":"10.1016\/j.jad.2020.11.035_bib0032","first-page":"77","article-title":"Modulation of Intrinsic Brain Activity by Electroconvulsive Therapy in Major Depression","volume":"1","author":"Leaver","year":"2016","journal-title":"Biol. Psychiatry Cogn. Neurosci. Neuroimaging"},{"issue":"1-2","key":"10.1016\/j.jad.2020.11.035_bib0033","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jad.2008.11.021","article-title":"Structural brain abnormalities in major depressive disorder: a selective review of recent MRI studies","volume":"117","author":"Lorenzetti","year":"2009","journal-title":"J Affect Disord"},{"key":"10.1016\/j.jad.2020.11.035_bib0034","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/j.nicl.2016.04.008","article-title":"The volumetric and shape changes of the putamen and thalamus in first episode, untreated major depressive disorder","volume":"11","author":"Lu","year":"2016","journal-title":"Neuroimage Clin"},{"issue":"12","key":"10.1016\/j.jad.2020.11.035_bib0035","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/S0006-3223(00)00228-6","article-title":"Increased neurogenesis in a model of electroconvulsive therapy","volume":"47","author":"Madsen","year":"2000","journal-title":"Biol Psychiatry"},{"issue":"1","key":"10.1016\/j.jad.2020.11.035_bib0036","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/sj.npp.1300565","article-title":"Electroconvulsive seizure treatment increases cell proliferation in rat frontal cortex","volume":"30","author":"Madsen","year":"2005","journal-title":"Neuropsychopharmacology"},{"issue":"24","key":"10.1016\/j.jad.2020.11.035_bib0037","doi-asserted-by":"crossref","first-page":"9104","DOI":"10.1523\/JNEUROSCI.20-24-09104.2000","article-title":"Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus","volume":"20","author":"Malberg","year":"2000","journal-title":"J Neurosci"},{"key":"10.1016\/j.jad.2020.11.035_bib0038","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1176\/jnp.9.3.471","article-title":"Limbic-cortical dysregulation: a proposed model of depression","volume":"9","author":"Mayberg","year":"1997","journal-title":"J. Neuropsychiatry Clin. Neurosci."},{"key":"10.1016\/j.jad.2020.11.035_bib0039","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1192\/bjp.134.4.382","article-title":"A new depression scale designed to be sensitive to change","volume":"134","author":"Montgomery","year":"1979","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.jad.2020.11.035_bib0040","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/s00406-015-0631-z","article-title":"Are morphological changes necessary to mediate the therapeutic effects of electroconvulsive therapy?","volume":"266","author":"Nickl-Jockschat","year":"2016","journal-title":"Eur. Arch. Psychiatry Clin. Neurosci."},{"key":"10.1016\/j.jad.2020.11.035_bib0041","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1097\/YCT.0b013e3181a95da8","article-title":"Increase in hippocampal volume after electroconvulsive therapy in patients with depression: a volumetric magnetic resonance imaging study","volume":"26","author":"Nordanskog","year":"2010","journal-title":"J. ECT"},{"key":"10.1016\/j.jad.2020.11.035_bib0042","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1111\/acps.12150","article-title":"Hippocampal volume in relation to clinical and cognitive outcome after electroconvulsive therapy in depression","volume":"129","author":"Nordanskog","year":"2014","journal-title":"Acta Psychiatr. Scand."},{"issue":"3","key":"10.1016\/j.jad.2020.11.035_bib0043","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.pscychresns.2013.05.004","article-title":"Reduced thalamic volumes in major depressive disorder","volume":"213","author":"Nugent","year":"2013","journal-title":"Psychiatry Res"},{"issue":"1","key":"10.1016\/j.jad.2020.11.035_bib0044","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1002\/hipo.22670","article-title":"Electroconvulsive stimulation results in long-term survival of newly generated hippocampal neurons in rats","volume":"27","author":"Olesen","year":"2017","journal-title":"Hippocampus"},{"key":"10.1016\/j.jad.2020.11.035_bib0045","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.nicl.2017.02.009","article-title":"The Global ECT-MRI Research Collaboration (GEMRIC): Establishing a multi-site investigation of the neural mechanisms underlying response to electroconvulsive therapy","volume":"14","author":"Oltedal","year":"2017","journal-title":"NeuroImage Clin"},{"issue":"8","key":"10.1016\/j.jad.2020.11.035_bib0046","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1016\/j.biopsych.2018.05.017","article-title":"Volume of the Human Hippocampus and Clinical Response Following Electroconvulsive Therapy","volume":"84","author":"Oltedal","year":"2018","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.jad.2020.11.035_bib0047","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.jad.2015.06.051","article-title":"Effect of electroconvulsive therapy on gray matter volume in major depressive disorder","volume":"186","author":"Ota","year":"2015","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2020.11.035_bib0048","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1007\/s11920-012-0322-7","article-title":"Where in the brain is depression?","volume":"14","author":"Pandya","year":"2012","journal-title":"Curr. Psychiatry Rep"},{"key":"10.1016\/j.jad.2020.11.035_bib0049","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.neuroimage.2011.02.046","article-title":"A Bayesian model of shape and appearance for subcortical brain segmentation","volume":"56","author":"Patenaude","year":"2011","journal-title":"Neuroimage"},{"issue":"18","key":"10.1016\/j.jad.2020.11.035_bib0050","doi-asserted-by":"crossref","first-page":"4894","DOI":"10.1523\/JNEUROSCI.0237-07.2007","article-title":"Antidepressant-induced neurogenesis in the hippocampus of adult nonhuman primates","volume":"27","author":"Perera","year":"2007","journal-title":"J Neurosci"},{"issue":"3","key":"10.1016\/j.jad.2020.11.035_bib0051","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1177\/1352458515593405","article-title":"Combined analysis of global and compartmental brain volume changes in early multiple sclerosis in clinical practice","volume":"22","author":"Pichler","year":"2016","journal-title":"Mult Scler"},{"issue":"11","key":"10.1016\/j.jad.2020.11.035_bib0052","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0141564","article-title":"Brain-Derived Neurotrophic Factor and Antidepressive Effect of Electroconvulsive Therapy: Systematic Review and Meta-Analyses of the Preclinical and Clinical Literature","volume":"10","author":"Polyakova","year":"2015","journal-title":"PLoS One"},{"issue":"6","key":"10.1016\/j.jad.2020.11.035_bib0053","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1001\/jamapsychiatry.2016.0316","article-title":"Prediction of Individual Response to Electroconvulsive Therapy via Machine Learning on Structural Magnetic Resonance Imaging Data","volume":"73","author":"Redlich","year":"2016","journal-title":"JAMA Psychiatry"},{"issue":"15","key":"10.1016\/j.jad.2020.11.035_bib0054","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1016\/j.jpsychires.2010.03.006","article-title":"Response and remission criteria in major depression\u2013a validation of current practice","volume":"44","author":"Riedel","year":"2010","journal-title":"J Psychiatr Res"},{"key":"10.1016\/j.jad.2020.11.035_bib0055","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/j.euroneuro.2015.12.036","article-title":"Electroconvulsive therapy increases temporal gray matter volume and cortical thickness","volume":"26","author":"Sartorius","year":"2016","journal-title":"Eur. Neuropsychopharmacol."},{"issue":"6","key":"10.1016\/j.jad.2020.11.035_bib0056","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1038\/mp.2015.69","article-title":"Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group","volume":"21","author":"Schmaal","year":"2016","journal-title":"Molecular psychiatry"},{"key":"10.1016\/j.jad.2020.11.035_bib0057","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1192\/bjp.156.4.551","article-title":"Time course of cerebra; magnetic resonance changes after electroconvulsive therapy","volume":"156","author":"Scott","year":"1990","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.jad.2020.11.035_bib0058","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1006\/nimg.2002.1040","article-title":"Accurate, robust, and automated longitudinal and cross-sectional brain change analysis","volume":"17","author":"Smith","year":"2002","journal-title":"Neuroimage"},{"issue":"Suppl 1","key":"10.1016\/j.jad.2020.11.035_bib0059","doi-asserted-by":"crossref","first-page":"S208","DOI":"10.1016\/j.neuroimage.2004.07.051","article-title":"Advances in functional and structural MR image analysis and implementation as FSL","volume":"23","author":"Smith","year":"2004","journal-title":"Neuroimage"},{"key":"10.1016\/j.jad.2020.11.035_bib0060","article-title":"International Consortium on the Genetics of Electroconvulsive Therapy and Severe Depressive Disorders (Gen-ECT-ic)","author":"Soda","year":"2019","journal-title":"Eur Arch Psychiatry Clin Neurosci"},{"key":"10.1016\/j.jad.2020.11.035_bib0061","first-page":"16","article-title":"Treatment-resistant depression","volume":"67","author":"Souery","year":"2006","journal-title":"J. Clin. Psychiatry"},{"issue":"3","key":"10.1016\/j.jad.2020.11.035_bib0062","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1179\/174313206X153842","article-title":"Diffusion weighted MRI in the early phase after electroconvulsive therapy","volume":"29","author":"Szabo","year":"2007","journal-title":"Neurol Res"},{"issue":"1","key":"10.1016\/j.jad.2020.11.035_bib0063","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1192\/bjp.2017.11","article-title":"Effect of electroconvulsive therapy on hippocampal and amygdala volumes: systematic review and meta-analysis","volume":"212","author":"Takamiya","year":"2018","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.jad.2020.11.035_bib0064","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.jpsychires.2019.08.001","article-title":"Thalamic volume, resting-state activity, and their association with the efficacy of electroconvulsive therapy","volume":"117","author":"Takamiya","year":"2019","journal-title":"J Psychiatr Res"},{"key":"10.1016\/j.jad.2020.11.035_bib0065","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.pscychresns.2013.09.004","article-title":"Electroconvulsive therapy increases hippocampal and amygdala volume in therapy refractory depression: A longitudinal pilot study","volume":"214","author":"Tendolkar","year":"2013","journal-title":"Psychiatry Res. - Neuroimaging"},{"key":"10.1016\/j.jad.2020.11.035_bib0021","doi-asserted-by":"crossref","first-page":"e874","DOI":"10.1038\/tp.2016.139","article-title":"Bilateral ECT induces bilateral increases in regional cortical thickness","volume":"6","author":"van Eijndhoven","year":"2016","journal-title":"Transl. Psychiatry"},{"issue":"4","key":"10.1016\/j.jad.2020.11.035_bib0066","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1016\/j.brs.2019.02.015","article-title":"Acute and subsequent continuation electroconvulsive therapy elevates serum BDNF levels in patients with major depression","volume":"12","author":"Vanicek","year":"2019","journal-title":"Brain Stimul"},{"issue":"5","key":"10.1016\/j.jad.2020.11.035_bib0067","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1111\/acps.13080","article-title":"Repetitive enhancement of serum BDNF subsequent to continuation ECT","volume":"140","author":"Vanicek","year":"2019","journal-title":"Acta Psychiatr Scand"},{"issue":"13","key":"10.1016\/j.jad.2020.11.035_bib0068","doi-asserted-by":"crossref","first-page":"2833","DOI":"10.1017\/S0033291714000348","article-title":"Reduced gray matter volume in the anterior cingulate, orbitofrontal cortex and thalamus as a function of mild depressive symptoms: a voxel-based morphometric analysis","volume":"44","author":"Webb","year":"2014","journal-title":"Psychol Med"},{"key":"10.1016\/j.jad.2020.11.035_bib0069","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.biopsych.2003.11.011","article-title":"Electroconvulsive seizures induce proliferation of NG2-expressing glial cells in adult rat amygdala","volume":"55","author":"Wennstr\u00f6m","year":"2004","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2020.11.035_bib0070","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1080\/00048670802277206","article-title":"Treatment-Resistant Depression: Critique of Current Approaches","volume":"42","author":"Wijeratne","year":"2008","journal-title":"Aust. New Zeal. J. Psychiatry"},{"key":"10.1016\/j.jad.2020.11.035_bib0071","doi-asserted-by":"crossref","first-page":"e754","DOI":"10.1038\/tp.2016.18","article-title":"Association of thalamic hyperactivity with treatment-resistant depression and poor response in early treatment for major depression: a resting-state fMRI study using fractional amplitude of low-frequency fluctuations","volume":"6","author":"Yamamura","year":"2016","journal-title":"Transl Psychiatry"}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032720329657?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032720329657?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T01:57:15Z","timestamp":1759024635000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165032720329657"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":71,"alternative-id":["S0165032720329657"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2020.11.035","relation":{},"ISSN":["0165-0327"],"issn-type":[{"value":"0165-0327","type":"print"}],"subject":[],"published":{"date-parts":[[2021,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Do increases in deep grey matter volumes after electroconvulsive therapy persist in patients with major depression? A longitudinal MRI-study","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2020.11.035","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}