{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T20:01:34Z","timestamp":1769976094146,"version":"3.49.0"},"reference-count":68,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,1,8]],"date-time":"2021-01-08T00:00:00Z","timestamp":1610064000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100014072","name":"Amsterdams Universiteitsfonds","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014072","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003195","name":"Ministerie van Economische Zaken","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003195","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.jad.2020.12.202","type":"journal-article","created":{"date-parts":[[2021,1,7]],"date-time":"2021-01-07T19:57:57Z","timestamp":1610049477000},"page":"1082-1089","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Skin autofluorescence of advanced glycation end products and mortality in affective disorders in the lifelines cohort study: A mediation analysis"],"prefix":"10.1016","volume":"282","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5085-1108","authenticated-orcid":false,"given":"Julia M.","family":"Hagen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arjen L.","family":"Sutterland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tessa","family":"Liefers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederike","family":"Schirmbeck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danny M.","family":"Cohn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anja","family":"Lok","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanno L.","family":"Tan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0361-3139","authenticated-orcid":false,"given":"Aeilko H.","family":"Zwinderman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lieuwe","family":"de Haan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jad.2020.12.202_bib0001","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1097\/01.crd.0000380842.14048.7e","article-title":"Diagnosis and management of the metabolic syndrome. An American heart association\/national heart, lung, and blood institute scientific statement. executive summary","volume":"13","author":"Grundy","year":"2005","journal-title":"Cardiol. Rev."},{"key":"10.1016\/j.jad.2020.12.202_bib0002","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1111\/acps.12265","article-title":"Effects of oxidative stress on fatty acid- and one-carbon-metabolism in psychiatric and cardiovascular disease comorbidity","volume":"130","author":"Assies","year":"2014","journal-title":"Acta Psychiatry Scand."},{"key":"10.1016\/j.jad.2020.12.202_bib0003","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.psychres.2002.12.004","article-title":"Antioxidant enzyme and malondialdehyde levels in patients with social phobia","volume":"159","author":"Atmaca","year":"2008","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.jad.2020.12.202_bib0004","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1037\/0022-3514.51.6.1173","article-title":"The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations","volume":"51","author":"Baron","year":"1986","journal-title":"J. Pers. Soc. Psychol."},{"key":"10.1016\/j.jad.2020.12.202_bib0005","doi-asserted-by":"crossref","first-page":"e92","DOI":"10.1038\/tp.2012.18","article-title":"The relationship between subtypes of depression and cardiovascular disease: a systematic review of biological models","volume":"2","author":"Baune","year":"2012","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.jad.2020.12.202_bib0006","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1001\/jamapsychiatry.2013.1111","article-title":"Autoimmune diseases and severe infections as risk factors for mood disorders: a nationwide study","volume":"70","author":"Benros","year":"2013","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.jad.2020.12.202_bib0008","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.psyneuen.2014.09.025","article-title":"Is depression associated with increased oxidative stress? A systematic review and meta-analysis","volume":"51","author":"Black","year":"2015","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.jad.2020.12.202_bib0007","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.psyneuen.2017.03.003","article-title":"The association between three major physiological stress systems and oxidative DNA and lipid damage","volume":"80","author":"Black","year":"2017","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.jad.2020.12.202_bib0009","doi-asserted-by":"crossref","first-page":"369","DOI":"10.4310\/SII.2009.v2.n3.a10","article-title":"Penalized methods for bi-level variable selection","volume":"2","author":"Breheny","year":"2009","journal-title":"Stat. Interface"},{"key":"10.1016\/j.jad.2020.12.202_bib0010","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1111\/j.1365-2362.2010.02317.x","article-title":"Advanced glycation end-products and the kidney","volume":"40","author":"Busch","year":"2010","journal-title":"Eur. J. Clin. Invest"},{"key":"10.1016\/j.jad.2020.12.202_bib0011","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1097\/JGP.0b013e31822001c1","article-title":"Dysthymia and depression increase risk of dementia and mortality among older veterans","volume":"20","author":"Byers","year":"2012","journal-title":"Am. J. Geriatr. Psychiatry"},{"key":"10.1016\/j.jad.2020.12.202_bib0012","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.118.009833","article-title":"Skin autofluorescence-indicated advanced glycation end products as predictors of cardiovascular and all-cause mortality in high-risk subjects: a systematic review and meta-analysis","volume":"7","author":"Cavero-Redondo","year":"2018","journal-title":"J. Am. Heart Assoc."},{"key":"10.1016\/j.jad.2020.12.202_bib0013","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.jad.2018.02.075","article-title":"Mortality risk associated with psychological distress and major depression: a population-based cohort study","volume":"234","author":"Chiu","year":"2018","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2020.12.202_bib0014","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1002\/da.22750","article-title":"Depressive and anxious symptoms and 20-year mortality: evidence from the Stirling county study","volume":"35","author":"Colman","year":"2018","journal-title":"Depress Anxiety"},{"key":"10.1016\/j.jad.2020.12.202_bib0015","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0165-0327(01)00413-X","article-title":"Excess mortality in depression: a meta-analysis of community studies","volume":"72","author":"Cuijpers","year":"2002","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2020.12.202_bib0016","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1161\/CIRCULATIONAHA.104.504159","article-title":"C-reactive protein and the 10-year incidence of coronary heart disease in older men and women: the cardiovascular health study","volume":"112","author":"Cushman","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.jad.2020.12.202_bib0017","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1001\/archgenpsychiatry.2010.36","article-title":"Association of anhedonia with recurrent major adverse cardiac events and mortality 1 year after acute coronary syndrome","volume":"67","author":"Davidson","year":"2010","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.jad.2020.12.202_bib0018","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.biopsych.2009.09.033","article-title":"A meta-analysis of cytokines in major depression","volume":"67","author":"Dowlati","year":"2010","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2020.12.202_bib0019","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.biopsych.2006.09.029","article-title":"Depression, C-reactive protein and two-year major adverse cardiac events in men after acute coronary syndromes","volume":"62","author":"Frasure-Smith","year":"2007","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2020.12.202_bib0020","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1161\/CIRCULATIONAHA.106.621854","article-title":"Advanced glycation end products: sparking the development of diabetic vascular injury","volume":"114","author":"Goldin","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.jad.2020.12.202_bib0021","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1161\/CIRCRESAHA.118.313764","article-title":"Oxidative stress contributes to microvascular endothelial dysfunction in men and women with major depressive disorder","volume":"124","author":"Greaney","year":"2019","journal-title":"Circ. Res."},{"key":"10.1016\/j.jad.2020.12.202_bib0022","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/j.cell.2010.01.025","article-title":"Immunity, inflammation, and cancer","volume":"140","author":"Grivennikov","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.jad.2020.12.202_bib0024","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.4088\/JCP.16m10972","article-title":"Advanced glycation end products in recent-onset psychosis indicate early onset of cardiovascular risk","volume":"78","author":"Hagen","year":"2017","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.jad.2020.12.202_bib0023","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.jad.2020.06.040","article-title":"Association between skin autofluorescence of advanced glycation end products and affective disorders in the lifelines cohort study","volume":"275","author":"Hagen","year":"2020","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2020.12.202_bib0025","article-title":"Dissecting the association between inflammation, metabolic dysregulation, and specific depressive symptoms: a genetic correlation and 2-sample Mendelian randomization study","author":"Kappelmann","year":"2020","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.jad.2020.12.202_bib0026","doi-asserted-by":"crossref","first-page":"2209","DOI":"10.1007\/s00394-017-1495-y","article-title":"Association between habitual dietary and lifestyle behaviours and skin autofluorescence (SAF), a marker of tissue accumulation of advanced glycation endproducts (AGEs), in healthy adults","volume":"57","author":"Kellow","year":"2018","journal-title":"Eur. J. Nutr."},{"key":"10.1016\/j.jad.2020.12.202_bib0027","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1016\/j.biopsych.2009.12.012","article-title":"Impact of depression and antidepressant treatment on heart rate variability: a review and meta-analysis","volume":"67","author":"Kemp","year":"2010","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2020.12.202_bib0028","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1192\/bjp.169.6.733","article-title":"Cardiovascular and respiratory risk factors and symptoms among general practice patients with long-term mental illness","volume":"169","author":"Kendrick","year":"1996","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.jad.2020.12.202_bib0029","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0137203","article-title":"Representativeness of the lifelines cohort study","volume":"10","author":"Klijs","year":"2015","journal-title":"PloS one"},{"key":"10.1016\/j.jad.2020.12.202_bib0030","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1089\/dia.2009.0113","article-title":"Reference values of skin autofluorescence","volume":"12","author":"Koetsier","year":"2010","journal-title":"Diabetes Technol. Therap."},{"key":"10.1016\/j.jad.2020.12.202_bib0031","doi-asserted-by":"crossref","first-page":"14416","DOI":"10.1364\/OE.18.014416","article-title":"Skin color independent assessment of aging using skin autofluorescence","volume":"18","author":"Koetsier","year":"2010","journal-title":"Opt. Express"},{"key":"10.1016\/j.jad.2020.12.202_bib0032","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.annepidem.2015.01.004","article-title":"Oxidative balance score as predictor of all-cause, cancer, and noncancer mortality in a biracial US cohort","volume":"25","author":"Kong","year":"2015","journal-title":"Ann. Epidemiol."},{"key":"10.1016\/j.jad.2020.12.202_bib0034","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1016\/j.jpsychires.2013.03.016","article-title":"Increased advanced glycation end-products (AGEs) assessed by skin autofluorescence in schizophrenia","volume":"47","author":"Kouidrat","year":"2013","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.jad.2020.12.202_bib0033","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.jpsychires.2015.04.023","article-title":"Advanced glycation end products and schizophrenia: a systematic review","volume":"66-67","author":"Kouidrat","year":"2015","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.jad.2020.12.202_bib0035","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1159\/000067810","article-title":"Antioxidant enzyme and malondialdehyde levels in patients with panic disorder","volume":"46","author":"Kuloglu","year":"2002","journal-title":"Neuropsychobiology"},{"key":"10.1016\/j.jad.2020.12.202_bib0036","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1038\/mp.2012.144","article-title":"Evidence for a differential role of HPA-axis function, inflammation and metabolic syndrome in melancholic versus atypical depression","volume":"18","author":"Lamers","year":"2013","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jad.2020.12.202_bib0037","doi-asserted-by":"crossref","first-page":"f2539","DOI":"10.1136\/bmj.f2539","article-title":"The gap in life expectancy from preventable physical illness in psychiatric patients in Western Australia: retrospective analysis of population based registers","volume":"346","author":"Lawrence","year":"2013","journal-title":"Bmj"},{"key":"10.1016\/j.jad.2020.12.202_bib0038","doi-asserted-by":"crossref","first-page":"604","DOI":"10.7326\/0003-4819-150-9-200905050-00006","article-title":"A new equation to estimate glomerular filtration rate","volume":"150","author":"Levey","year":"2009","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.jad.2020.12.202_bib0039","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1007\/s00125-004-1451-2","article-title":"Simple non-invasive assessment of advanced glycation endproduct accumulation","volume":"47","author":"Meerwaldt","year":"2004","journal-title":"Diabetologia"},{"key":"10.1016\/j.jad.2020.12.202_bib0040","doi-asserted-by":"crossref","first-page":"3687","DOI":"10.1681\/ASN.2005020144","article-title":"Skin autofluorescence, a measure of cumulative metabolic stress and advanced glycation end products, predicts mortality in hemodialysis patients","volume":"16","author":"Meerwaldt","year":"2005","journal-title":"J. Am. Soc. Nephrol.: JASN"},{"key":"10.1016\/j.jad.2020.12.202_bib0041","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1192\/bjp.bp.115.171975","article-title":"Increased mortality among people with anxiety disorders: total population study","volume":"209","author":"Meier","year":"2016","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.jad.2020.12.202_bib0042","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1007\/s00127-016-1284-6","article-title":"Anxiety disorders and all-cause mortality: systematic review and meta-analysis","volume":"51","author":"Miloyan","year":"2016","journal-title":"Soc. Psychiatry Psychiatry Epidemiol."},{"key":"10.1016\/j.jad.2020.12.202_bib0044","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1089\/dia.2006.8.523","article-title":"Skin autofluorescence, a novel marker for glycemic and oxidative stress-derived advanced glycation endproducts: an overview of current clinical studies, evidence, and limitations","volume":"8","author":"Mulder","year":"2006","journal-title":"Diabetes Technol. Therap."},{"key":"10.1016\/j.jad.2020.12.202_bib0043","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1007\/BF03086239","article-title":"Skin autofluorescence is elevated in acute myocardial infarction and is associated with the one-year incidence of major adverse cardiac events","volume":"17","author":"Mulder","year":"2009","journal-title":"Neth. Heart J."},{"key":"10.1016\/j.jad.2020.12.202_bib0045","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1046\/j.1523-1747.2001.01285.x","article-title":"Autofluorescence of human skin is age-related after correction for skin pigmentation and redness","volume":"116","author":"Na","year":"2001","journal-title":"J. Invest Dermatol."},{"key":"10.1016\/j.jad.2020.12.202_bib0046","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1001\/archpsyc.56.10.889","article-title":"Minor and major depression and the risk of death in older persons","volume":"56","author":"Penninx","year":"1999","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.jad.2020.12.202_bib0047","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/3818196","article-title":"Advanced glycation end products (AGEs): biochemistry, signaling, analytical methods, and epigenetic effects","volume":"2020","author":"Perrone","year":"2020","journal-title":"Oxid. Med. Cell Longev."},{"key":"10.1016\/j.jad.2020.12.202_bib0048","series-title":"R: A Language and Environment for Statistical Computing","year":"2020"},{"key":"10.1016\/j.jad.2020.12.202_bib0050","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/s40618-018-0903-3","article-title":"Increased serum interleukin-37 (IL-37) levels correlate with oxidative stress parameters in Hashimoto's thyroiditis","volume":"42","author":"Ruggeri","year":"2019","journal-title":"J. Endocrinol. Invest"},{"key":"10.1016\/j.jad.2020.12.202_bib0049","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1007\/s40618-020-01231-7","article-title":"Serum levels of advanced glycation end products (AGEs) are increased and their soluble receptor (sRAGE) reduced in Hashimoto's thyroiditis","volume":"43","author":"Ruggeri","year":"2020","journal-title":"J. Endocrinol. Invest"},{"key":"10.1016\/j.jad.2020.12.202_bib0051","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1007\/s12026-017-8960-9","article-title":"Increased lipid and protein oxidation and lowered anti-oxidant defenses in systemic lupus erythematosus are associated with severity of illness, autoimmunity, increased adhesion molecules, and Th1 and Th17 immune shift","volume":"66","author":"Scavuzzi","year":"2018","journal-title":"Immunol. Res."},{"key":"10.1016\/j.jad.2020.12.202_bib0052","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1093\/ije\/dyu229","article-title":"Cohort profile: lifelines, a three-generation cohort study and biobank","volume":"44","author":"Scholtens","year":"2015","journal-title":"Int. J. Epidemiol."},{"key":"10.1016\/j.jad.2020.12.202_bib0053","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/j.jad.2018.05.079","article-title":"Depression and anxiety symptoms are associated with prooxidant-antioxidant balance: a population-based study","volume":"238","author":"Shafiee","year":"2018","journal-title":"J. Affect. Disord."},{"issue":"Suppl 20","key":"10.1016\/j.jad.2020.12.202_bib0054","first-page":"22","article-title":"The mini-international neuropsychiatric interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10","volume":"59","author":"Sheehan","year":"1998","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.jad.2020.12.202_bib0055","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1097\/PSY.0000000000000513","article-title":"Perceived stress, depressive symptoms, and oxidative DNA damage","volume":"80","author":"Shimanoe","year":"2018","journal-title":"Psychosom. Med."},{"key":"10.1016\/j.jad.2020.12.202_bib0056","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1097\/PSY.0b013e31820ad12b","article-title":"Depression and hypothalamic-pituitary-adrenal activation: a quantitative summary of four decades of research","volume":"73","author":"Stetler","year":"2011","journal-title":"Psychosom. Med."},{"key":"10.1016\/j.jad.2020.12.202_bib0057","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/s10654-007-9204-4","article-title":"Universal risk factors for multifactorial diseases: LifeLines: a three-generation population-based study","volume":"23","author":"Stolk","year":"2008","journal-title":"Eur. J. Epidemiol."},{"key":"10.1016\/j.jad.2020.12.202_bib0058","series-title":"Modeling Survival Data: Estending the Cox Model","author":"Therneau","year":"2000"},{"key":"10.1016\/j.jad.2020.12.202_bib0060","first-page":"1","article-title":"Mice: multivariate imputation by chained equations in R","volume":"45","author":"van Buuren","year":"2011","journal-title":"J. Stat. Softw."},{"key":"10.1016\/j.jad.2020.12.202_bib0059","series-title":"Flexible Imputation of Missing Data","author":"van Buuren","year":"2012"},{"key":"10.1016\/j.jad.2020.12.202_bib0061","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1002\/da.22527","article-title":"Advanced glycation end product (AGE) accumulation in the skin is associated with depression: the Maastricht study","volume":"34","author":"van Dooren","year":"2017","journal-title":"Depress Anxiety"},{"key":"10.1016\/j.jad.2020.12.202_bib0063","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1111\/eci.12627","article-title":"Lifestyle and clinical determinants of skin autofluorescence in a population-based cohort study","volume":"46","author":"van Waateringe","year":"2016","journal-title":"Eur. J. Clin. Invest"},{"key":"10.1016\/j.jad.2020.12.202_bib0062","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1007\/s00125-018-4769-x","article-title":"Skin autofluorescence predicts incident type 2 diabetes, cardiovascular disease and mortality in the general population","volume":"62","author":"van Waateringe","year":"2019","journal-title":"Diabetologia"},{"key":"10.1016\/j.jad.2020.12.202_bib0064","series-title":"Modern Applied Statistics with S","author":"Venables","year":"2002"},{"key":"10.1016\/j.jad.2020.12.202_bib0065","doi-asserted-by":"crossref","first-page":"39027","DOI":"10.1074\/jbc.M006700200","article-title":"Effect of collagen turnover on the accumulation of advanced glycation end products","volume":"275","author":"Verzijl","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jad.2020.12.202_bib0066","unstructured":"WHO Collaborating centre for drug statistics methodology [WHO], 2019. ATC\/DDD Index 2019."},{"key":"10.1016\/j.jad.2020.12.202_bib0067","doi-asserted-by":"crossref","first-page":"101","DOI":"10.4161\/oxim.3.2.11148","article-title":"Advanced glycation end products, oxidative stress and diabetic nephropathy","volume":"3","author":"Yamagishi","year":"2010","journal-title":"Oxid. Med. Cell Longev."},{"key":"10.1016\/j.jad.2020.12.202_bib0068","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.bcp.2019.05.027","article-title":"Apigenin and its methylglyoxal-adduct inhibit advanced glycation end products-induced oxidative stress and inflammation in endothelial cells","volume":"166","author":"Zhou","year":"2019","journal-title":"Biochem. Pharmacol."}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032721000094?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032721000094?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T02:12:47Z","timestamp":1759025567000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165032721000094"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":68,"alternative-id":["S0165032721000094"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2020.12.202","relation":{},"ISSN":["0165-0327"],"issn-type":[{"value":"0165-0327","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Skin autofluorescence of advanced glycation end products and mortality in affective disorders in the lifelines cohort study: A mediation analysis","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2020.12.202","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}