{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T00:31:23Z","timestamp":1790555483574,"version":"4.1.0"},"reference-count":49,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.jad.2021.01.002","type":"journal-article","created":{"date-parts":[[2021,1,7]],"date-time":"2021-01-07T19:55:36Z","timestamp":1610049336000},"page":"939-944","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Association between skin disorders and depression in children and adolescents: A retrospective case-control study"],"prefix":"10.1016","volume":"282","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5189-4516","authenticated-orcid":false,"given":"Franka","family":"Teichgr\u00e4ber","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis","family":"Jacob","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ai","family":"Koyanagi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Il","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Seiringer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2124-7227","authenticated-orcid":false,"given":"Karel","family":"Kostev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Suppl 7","key":"10.1016\/j.jad.2021.01.002_bib0001","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/ddg.13906","article-title":"Diagnosis and treatment of xerosis cutis - a position paper","volume":"17","author":"Augustin","year":"2019","journal-title":"J. Deutsch. Dermatol. Gesell.\u00a0=\u00a0J. German Soc. Dermatol."},{"issue":"S1","key":"10.1016\/j.jad.2021.01.002_bib0002","first-page":"1","article-title":"P-259 - Prevalence f adolescent depression in Europe","volume":"27","author":"Balazs","year":"2012","journal-title":"Eur. Psychiatry"},{"issue":"2","key":"10.1016\/j.jad.2021.01.002_bib0003","doi-asserted-by":"crossref","first-page":"227","DOI":"10.2340\/00015555-2200","article-title":"Are common skin diseases among norwegian dermatological outpatients associated with psychological problems compared with controls? An observational study","volume":"96","author":"Balieva","year":"2015","journal-title":"Acta Dermato Venereol."},{"issue":"11","key":"10.1016\/j.jad.2021.01.002_bib0004","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1111\/jdv.12315","article-title":"Psychiatric symptomatology and health-related quality of life in children and adolescents with alopecia areata","volume":"28","author":"Bilgi\u00e7","year":"2014","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"issue":"1","key":"10.1016\/j.jad.2021.01.002_bib0005","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-018-24653-z","article-title":"Psychological stress deteriorates skin barrier function by activating 11\u03b2-hydroxysteroid dehydrogenase 1 and the HPA axis","volume":"8","author":"Choe","year":"2018","journal-title":"Sci. Rep."},{"issue":"4","key":"10.1016\/j.jad.2021.01.002_bib0006","article-title":"Interventions for hand eczema","volume":"4","author":"Christoffers","year":"2019","journal-title":"Cochrane Database Syst. Rev."},{"issue":"2","key":"10.1016\/j.jad.2021.01.002_bib0007","doi-asserted-by":"crossref","first-page":"e239","DOI":"10.1111\/j.1468-3083.2012.04578.x","article-title":"Relationship between itch and psychological status of patients with atopic dermatitis","volume":"27","author":"Chrostowska-Plak","year":"2013","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"issue":"3","key":"10.1016\/j.jad.2021.01.002_bib0008","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1111\/j.1365-2133.2011.10714.x","article-title":"Psychiatric comorbidities in patients with alopecia areata in Taiwan: a case-control study","volume":"166","author":"Chu","year":"2012","journal-title":"Br. J. Dermatol."},{"issue":"12","key":"10.1016\/j.jad.2021.01.002_bib0009","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1111\/j.1469-7610.2006.01682.x","article-title":"Is there an epidemic of child or adolescent depression?","volume":"47","author":"Costello","year":"2006","journal-title":"J. Child Psychol. Psychiatry Allied Discip."},{"issue":"2","key":"10.1016\/j.jad.2021.01.002_bib0010","first-page":"464","article-title":"Dermatologists across Europe underestimate depression and anxiety: results from 3635 dermatological consultations","volume":"179","author":"Dalgard","year":"2017","journal-title":"Br. J. Dermatol."},{"issue":"2","key":"10.1016\/j.jad.2021.01.002_bib0012","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.mehy.2012.11.027","article-title":"How does epidermal pathology interact with mental state?","volume":"80","author":"Denda","year":"2013","journal-title":"Med. Hypotheses"},{"issue":"2","key":"10.1016\/j.jad.2021.01.002_bib0013","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.jpsychores.2011.01.007","article-title":"Environmental stress but not subjective distress in children or adolescents with alopecia areata","volume":"71","author":"D\u00edaz-Atienza","year":"2011","journal-title":"J. Psychosom. Res."},{"issue":"1","key":"10.1016\/j.jad.2021.01.002_bib0014","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.jaad.2013.01.022","article-title":"IQoL-32: a new ichthyosis-specific measure of quality of life","volume":"69","author":"Dreyfus","year":"2013","journal-title":"J. Am. Acad. Dermatol."},{"issue":"4","key":"10.1016\/j.jad.2021.01.002_bib0015","doi-asserted-by":"crossref","first-page":"406","DOI":"10.5021\/ad.2012.24.4.406","article-title":"Effect of the pruritus on the quality of life: a preliminary study","volume":"24","author":"Erturk","year":"2012","journal-title":"Ann. Dermatol."},{"issue":"3","key":"10.1016\/j.jad.2021.01.002_bib0017","first-page":"293","article-title":"The frequency of common skin conditions in preschool-age children in Australia: atopic dermatitis","volume":"137","author":"Foley","year":"2001","journal-title":"Arch. Dermatol."},{"issue":"3","key":"10.1016\/j.jad.2021.01.002_bib0018","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1192\/bjp.179.3.210","article-title":"The Maudsley long-term follow-up of child and adolescent depression: I. Psychiatric outcomes in adulthood","volume":"179","author":"Fombonne","year":"2001","journal-title":"Br. J. Psychiatry"},{"issue":"4","key":"10.1016\/j.jad.2021.01.002_bib0019","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1159\/000205524","article-title":"Adolescents with skin disease have specific quality of life issues","volume":"218","author":"Golics","year":"2009","journal-title":"Dermatology (Basel, Switzerland)"},{"issue":"2","key":"10.1016\/j.jad.2021.01.002_bib0020","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1001\/jamadermatol.2019.4126","article-title":"Use of epidermal growth factor receptor inhibitor erlotinib to treat palmoplantar keratoderma in patients with olmsted syndrome caused by TRPV3 mutations","volume":"156","author":"Greco","year":"2020","journal-title":"JAMA Dermatol."},{"issue":"4","key":"10.1016\/j.jad.2021.01.002_bib0021","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1007\/s00198-016-3842-x","article-title":"Impact of attention deficit hyperactivity disorder therapy on fracture risk in children treated in German pediatric practices","volume":"28","author":"Jacob","year":"2017","journal-title":"Osteoporos. Int."},{"issue":"1","key":"10.1016\/j.jad.2021.01.002_bib0022","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1111\/pai.12657","article-title":"Association between preschool eczema and medication for attention-deficit\/hyperactivity disorder in school age","volume":"28","author":"Johansson","year":"2017","journal-title":"Pediatr. Allergy Immunol."},{"issue":"6","key":"10.1016\/j.jad.2021.01.002_bib0023","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1016\/S0190-9622(03)02112-1","article-title":"Quality of life in patients with allergic contact dermatitis","volume":"49","author":"Kadyk","year":"2003","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.jad.2021.01.002_bib0024","doi-asserted-by":"crossref","first-page":"e30","DOI":"10.1017\/S2045796019000180","article-title":"The excess costs of depression: a systematic review and meta-analysis","volume":"29","author":"K\u00f6nig","year":"2019","journal-title":"Epidemiol. Psychiatric Sci."},{"key":"10.1016\/j.jad.2021.01.002_bib0025","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.psychres.2019.03.045","article-title":"Duration of sick leave in patients with depression treated by general practitioners and psychiatrists","volume":"279","author":"Konrad","year":"2019","journal-title":"Psychiatry Res."},{"issue":"274","key":"10.1016\/j.jad.2021.01.002_bib0026","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.jad.2020.05.074","article-title":"Increased prevalence of depression, anxiety, and adjustment and somatoform disorders in transsexual individuals","volume":"1","author":"Konrad","year":"2020","journal-title":"J. Affect. Disord."},{"issue":"245","key":"10.1016\/j.jad.2021.01.002_bib0027","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.jad.2018.11.014","article-title":"Association between chronic somatic conditions and depression in children and adolescents: a retrospective study of 13,326 patients","volume":"15","author":"Kostev","year":"2019","journal-title":"J. Affect. Disord."},{"issue":"1","key":"10.1016\/j.jad.2021.01.002_bib0028","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s12888-016-1160-7","article-title":"Association of atopic dermatitis with depressive symptoms and suicidal behaviors among adolescents in Korea: the 2013 Korean Youth Risk Behavior Survey","volume":"17","author":"Lee","year":"2017","journal-title":"BMC Psychiatry"},{"issue":"8","key":"10.1016\/j.jad.2021.01.002_bib0029","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1111\/j.1742-1241.2006.01047.x","article-title":"Quality of life and childhood atopic dermatitis: the misery of living with childhood eczema","volume":"60","author":"Lewis-Jones","year":"2006","journal-title":"Int. J. Clin. Pract."},{"issue":"1","key":"10.1016\/j.jad.2021.01.002_bib0030","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1111\/j.1346-8138.2011.01295.x","article-title":"Health-related quality of life in patients with atopic dermatitis","volume":"39","author":"Maksimovi\u0107","year":"2012","journal-title":"J. Dermatol."},{"issue":"10161","key":"10.1016\/j.jad.2021.01.002_bib0031","doi-asserted-by":"crossref","first-page":"2299","DOI":"10.1016\/S0140-6736(18)31948-2","article-title":"Depression","volume":"392","author":"Malhi","year":"2018","journal-title":"Lancet (London, England)"},{"issue":"11","key":"10.1016\/j.jad.2021.01.002_bib0032","doi-asserted-by":"crossref","first-page":"e442","DOI":"10.1371\/journal.pmed.0030442","article-title":"Projections of global mortality and burden of disease from 2002 to 2030","volume":"3","author":"Mathers","year":"2006","journal-title":"PLOS Med."},{"issue":"2","key":"10.1016\/j.jad.2021.01.002_bib0033","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1111\/bjd.17203","article-title":"Management of congenital ichthyoses: European guidelines of care, part one","volume":"180","author":"Mazereeuw-Hautier","year":"2019","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jad.2021.01.002_bib0034","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.psychres.2017.05.012","article-title":"Role of IL-8, CRP and epidermal growth factor in depression and anxiety patients treated with mindfulness-based therapy or cognitive behavioral therapy in primary health care","volume":"254","author":"Memon","year":"2017","journal-title":"Psychiatry Res."},{"issue":"2","key":"10.1016\/j.jad.2021.01.002_bib0035","doi-asserted-by":"crossref","first-page":"211","DOI":"10.4103\/0019-5154.152564","article-title":"Gender differences in depression and anxiety among atopic dermatitis patients","volume":"60","author":"Mina","year":"2015","journal-title":"Indian J. Dermatol."},{"issue":"4","key":"10.1016\/j.jad.2021.01.002_bib0036","article-title":"Increasing incidence of skin disorders in children? A comparison between 1987 and 2001","volume":"6","author":"Mohammedamin","year":"2006","journal-title":"BMC Dermatol."},{"issue":"7","key":"10.1016\/j.jad.2021.01.002_bib0037","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1001\/jamadermatol.2017.0499","article-title":"Pediatric psoriasis comorbidity screening guidelines","volume":"153","author":"Osier","year":"2017","journal-title":"JAMA Dermatol."},{"issue":"4","key":"10.1016\/j.jad.2021.01.002_bib0038","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1159\/000499564","article-title":"Association of Psoriasis with Psychiatric Hospitalization in United States children and adults","volume":"235","author":"Patel","year":"2019","journal-title":"Dermatology (Basel, Switzerland)"},{"issue":"2","key":"10.1016\/j.jad.2021.01.002_bib0039","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.det.2007.01.006","article-title":"Drug reactions affecting the nail unit: diagnosis and management","volume":"25","author":"Piraccini","year":"2007","journal-title":"Dermatol. Clin."},{"issue":"1","key":"10.1016\/j.jad.2021.01.002_bib0040","doi-asserted-by":"crossref","first-page":"63","DOI":"10.4274\/jcrpe.1515","article-title":"Social anxiety, depression and self-esteem in obese adolescent girls with acanthosis nigricans","volume":"7","author":"Pirgon","year":"2015","journal-title":"J. Clin. Res. Pediatr. Endocrinol."},{"issue":"12","key":"10.1016\/j.jad.2021.01.002_bib0041","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1111\/j.1440-1754.2006.00979.x","article-title":"Acne, anxiety, depression and suicide in teenagers: a cross-sectional survey of New Zealand secondary school students","volume":"42","author":"Purvis","year":"2006","journal-title":"J. Paediatr. Child Health"},{"issue":"3","key":"10.1016\/j.jad.2021.01.002_bib0042","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/j.jaad.2018.03.017","article-title":"Association of atopic dermatitis with depression, anxiety, and suicidal ideation in children and adults: a systematic review and meta-analysis","volume":"79","author":"R\u00f8nnstad","year":"2018","journal-title":"J. Am. Acad. Dermatol."},{"issue":"1","key":"10.1016\/j.jad.2021.01.002_bib0043","first-page":"1","article-title":"Why match? Investigating matched case-control study designs with causal effect estimation","volume":"5","author":"Rose","year":"2009","journal-title":"Int. J. Biostat."},{"key":"10.1016\/j.jad.2021.01.002_bib0044","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/nyas.12738","article-title":"The interface of depression and cardiovascular disease: therapeutic implications","volume":"1345","author":"Seligman","year":"2015","journal-title":"Ann. New York Acad. Sci."},{"issue":"2","key":"10.1016\/j.jad.2021.01.002_bib0045","doi-asserted-by":"crossref","first-page":"67","DOI":"10.4103\/2229-5178.153002","article-title":"Nail as a window of systemic diseases","volume":"6","author":"Singal","year":"2015","journal-title":"Indian Dermatol. Online J."},{"issue":"7526","key":"10.1016\/j.jad.2021.01.002_bib0046","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1038\/515180a","article-title":"Mental health: a world of depression","volume":"515","author":"Smith","year":"2014","journal-title":"Nature"},{"issue":"12","key":"10.1016\/j.jad.2021.01.002_bib0047","article-title":"Psychological therapies for anxiety and depression in children and adolescents with long-term physical conditions","volume":"12","author":"Thabrew","year":"2018","journal-title":"Cochrane Database Syst. Rev."},{"issue":"8","key":"10.1016\/j.jad.2021.01.002_bib0048","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1038\/sj.mp.4001274","article-title":"Atopy and depression: results from the Northern Finland 1966 Birth Cohort Study","volume":"8","author":"Timonen","year":"2003","journal-title":"Mole. Psychiatry"},{"issue":"4","key":"10.1016\/j.jad.2021.01.002_bib0049","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1001\/jamadermatol.2018.4398","article-title":"Assessment of a bidirectional association between major depressive disorder and alopecia areata","volume":"155","author":"Vallerand","year":"2019","journal-title":"JAMA Dermatol."},{"issue":"5","key":"10.1016\/j.jad.2021.01.002_bib0050","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1016\/j.jaad.2018.11.047","article-title":"Vitiligo and major depressive disorder: a bidirectional population-based cohort study","volume":"80","author":"Vallerand","year":"2019","journal-title":"J. Am. Acad. Dermatol."},{"issue":"1","key":"10.1016\/j.jad.2021.01.002_bib0051","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/ced.14021","article-title":"The impact of chronic skin disease in adolescence and the need for specialist adolescent services","volume":"45","author":"Hunt","year":"2020","journal-title":"Clin. Exp. Dermatol."}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032721000033?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032721000033?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T02:06:42Z","timestamp":1759025202000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165032721000033"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":49,"alternative-id":["S0165032721000033"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2021.01.002","relation":{},"ISSN":["0165-0327"],"issn-type":[{"value":"0165-0327","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association between skin disorders and depression in children and adolescents: A retrospective case-control study","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2021.01.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}