{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T01:07:29Z","timestamp":1792199249861,"version":"4.4.0"},"reference-count":142,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,1,20]],"date-time":"2022-01-20T00:00:00Z","timestamp":1642636800000},"content-version":"vor","delay-in-days":294,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1016\/j.jad.2021.02.004","type":"journal-article","created":{"date-parts":[[2021,2,6]],"date-time":"2021-02-06T02:38:37Z","timestamp":1612579117000},"page":"85-97","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":166,"special_numbering":"C","title":["Depressive and anxiety disorders in concert\u2013A synthesis of findings on comorbidity in the NESDA study"],"prefix":"10.1016","volume":"284","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8475-5256","authenticated-orcid":false,"given":"Wendela G.","family":"ter Meulen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stasja","family":"Draisma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert M.","family":"van Hemert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert A.","family":"Schoevers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralph W.","family":"Kupka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aartjan T.F.","family":"Beekman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brenda W.J.H.","family":"Penninx","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jad.2021.02.004_bib0001","doi-asserted-by":"crossref","DOI":"10.1017\/S0033291709990250","article-title":"Exploring the feasibility of a meta-structure for DSM-V and ICD-11: could it improve utility and validity?","author":"Andrews","year":"2009","journal-title":"Psychol. Med."},{"key":"10.1016\/j.jad.2021.02.004_bib0002","article-title":"Analysis of shared heritability in common disorders of the brain","author":"Anttila","year":"2018","journal-title":"Science (80-.)"},{"key":"10.1016\/j.jad.2021.02.004_bib0003","doi-asserted-by":"crossref","DOI":"10.1348\/000712608X377117","article-title":"Standardized or simple effect size: what should be reported?","author":"Baguley","year":"2009","journal-title":"Br. J. Psychol."},{"key":"10.1016\/j.jad.2021.02.004_bib0004","doi-asserted-by":"crossref","DOI":"10.1001\/jamapsychiatry.2017.2164","article-title":"The unified protocol for transdiagnostic treatment of Emotional Disorders compared with diagnosis-specific protocols for anxiety disorders: a randomized clinical trial","author":"Barlow","year":"2017","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0005","doi-asserted-by":"crossref","DOI":"10.4088\/JCP.13m08837","article-title":"Two-year course trajectories of anxiety disorders: do DSM classifications matter?","author":"Batelaan","year":"2014","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0006","doi-asserted-by":"crossref","DOI":"10.1037\/0022-006X.56.6.893","article-title":"An inventory for measuring clinical anxiety: psychometric properties","author":"Beck","year":"1988","journal-title":"J. Consult. Clin. Psychol."},{"issue":"11","key":"10.1016\/j.jad.2021.02.004_bib0137","first-page":"915","article-title":"Stagering en profilering van psychiatrische stoornissen [Staging and profiling of psychiatric disorders].","volume":"54","author":"Beekman","year":"2012","journal-title":"Tijdschr. Psychiatr."},{"key":"10.1016\/j.jad.2021.02.004_bib0007","doi-asserted-by":"crossref","DOI":"10.1037\/a0033048","article-title":"Anxiety and related outcomes in young adults 7 to 19 years after receiving treatment for child anxiety","author":"Benjamin","year":"2013","journal-title":"J. Consult. Clin. Psychol."},{"key":"10.1016\/j.jad.2021.02.004_bib0008","article-title":"Psychiatric morbidity, service use, and need for care in the general population: results of the Netherlands Mental Health Survey and incidence study","author":"Bijl","year":"2000","journal-title":"Am. J. Public Health."},{"key":"10.1016\/j.jad.2021.02.004_bib0009","doi-asserted-by":"crossref","DOI":"10.1017\/S0033291716002828","article-title":"Oxidative stress in major depressive and anxiety disorders, and the association with antidepressant use; results from a large adult cohort","author":"Black","year":"2017","journal-title":"Psychol. Med."},{"key":"10.1016\/j.jad.2021.02.004_bib0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.jad.2017.09.003","article-title":"Uric acid in major depressive and anxiety disorders","author":"Black","year":"2018","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2021.02.004_bib0011","doi-asserted-by":"crossref","DOI":"10.1177\/0004867419887804","article-title":"A clinical staging approach to improving diagnostics in anxiety disorders: is it the way to go?","author":"Bokma","year":"2020","journal-title":"Aust. N. Z. J. Psychiatry."},{"key":"10.1016\/j.jad.2021.02.004_bib0012","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1159\/000362563","article-title":"The four-year course of major depressive disorder: the role of staging and risk factor determination","volume":"83","author":"Boschloo","year":"2014","journal-title":"Psychother. Psychosom."},{"key":"10.1016\/j.jad.2021.02.004_bib0013","doi-asserted-by":"crossref","DOI":"10.1016\/j.jad.2010.12.014","article-title":"Comorbidity and risk indicators for alcohol use disorders among persons with anxiety and\/or depressive disorders: findings from the Netherlands study of depression and anxiety (NESDA)","author":"Boschloo","year":"2011","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2021.02.004_bib0014","doi-asserted-by":"crossref","DOI":"10.4088\/JCP.12m08159","article-title":"Depressive and anxiety disorders predicting first incidence of alcohol use disorders: results of the netherlands study of depression and anxiety (nesda)","author":"Boschloo","year":"2013","journal-title":"J. Clin. Psychiatry."},{"key":"10.1016\/j.jad.2021.02.004_bib0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.jad.2015.01.022","article-title":"Long-lasting effects of affective disorders and childhood trauma on dispositional optimism","author":"Broekhof","year":"2015","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2021.02.004_bib0016","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.jad.2016.02.053","article-title":"Prevalence of ADHD symptoms across clinical stages of major depressive disorder","volume":"197","author":"Bron","year":"2016","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2021.02.004_bib0017","doi-asserted-by":"crossref","DOI":"10.1037\/a0016608","article-title":"A proposal for a dimensional classification system based on the shared features of the DSM-IV anxiety and mood disorders: implications for assessment and treatment","author":"Brown","year":"2009","journal-title":"Psychol. Assess."},{"key":"10.1016\/j.jad.2021.02.004_bib0018","doi-asserted-by":"crossref","DOI":"10.1037\/0021-843X.110.4.585","article-title":"Current and lifetime comorbidity of the DSM-IV anxiety and mood disorders in a large clinical sample","author":"Brown","year":"2001","journal-title":"J. Abnorm. Psychol."},{"key":"10.1016\/j.jad.2021.02.004_bib0019","doi-asserted-by":"crossref","DOI":"10.1038\/mp.2014.83","article-title":"Chronic depression is associated with a pronounced decrease in serum brain-derived neurotrophic factor over time","author":"Bus","year":"2015","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0020","doi-asserted-by":"crossref","DOI":"10.1002\/1097-0258(20001130)19:22<3127::AID-SIM784>3.0.CO;2-M","article-title":"A simple method for converting an odds ratio to effect size for use in meta-analysis","author":"Chinn","year":"2000","journal-title":"Stat. Med."},{"key":"10.1016\/j.jad.2021.02.004_bib0021","doi-asserted-by":"crossref","DOI":"10.1002\/da.22740","article-title":"Evaluating dimensional models of psychopathology in outpatients diagnosed with emotional disorders: a cautionary tale","author":"Conway","year":"2018","journal-title":"Depress. Anxiety"},{"key":"10.1016\/j.jad.2021.02.004_bib0022","doi-asserted-by":"crossref","DOI":"10.1016\/j.jad.2019.08.023","article-title":"Trait anger and anger attacks in relation to depressive and anxiety disorders","author":"De Bles","year":"2019","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2021.02.004_bib0023","doi-asserted-by":"crossref","DOI":"10.1176\/appi.ajp.159.4.620","article-title":"Risk factors for 12-month comorbidity of mood, anxiety, and substance use disorders: findings from the Netherlands Mental Health Survey and Incidence Study","author":"De Graaf","year":"2002","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0024","doi-asserted-by":"crossref","DOI":"10.1007\/s00127-003-0597-4","article-title":"Temporal sequencing of lifetime mood disorders in relation to comorbid anxiety and substance use disorders - findings from the Netherlands Mental Health Survey and Incidence Study","author":"De Graaf","year":"2003","journal-title":"Soc. Psychiatry Psychiatr. Epidemiol."},{"key":"10.1016\/j.jad.2021.02.004_bib0025","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0106907","article-title":"The Association of depression and anxiety with pain: a study from NESDA","author":"De Heer","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.jad.2021.02.004_bib0026","doi-asserted-by":"crossref","DOI":"10.1016\/j.psychres.2010.07.003","article-title":"Are sedentary television watching and computer use behaviors associated with anxiety and depressive disorders?","author":"De Wit","year":"2011","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.jad.2021.02.004_bib0027","doi-asserted-by":"crossref","DOI":"10.1002\/da.20738","article-title":"Depressive and anxiety disorders and the association with obesity, physical, and social activities","author":"De Wit","year":"2010","journal-title":"Depress. Anxiety"},{"key":"10.1016\/j.jad.2021.02.004_bib0028","doi-asserted-by":"crossref","DOI":"10.1016\/j.psychres.2015.02.025","article-title":"Depressive and anxiety disorders: associated with losing or gaining weight over 2 years?","author":"De Wit","year":"2015","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.jad.2021.02.004_bib0029","doi-asserted-by":"crossref","DOI":"10.1002\/da.22949","article-title":"Sleep, circadian rhythm, and physical activity patterns in depressive and anxiety disorders: a 2-week ambulatory assessment study","author":"Difrancesco","year":"2019","journal-title":"Depress. Anxiety."},{"key":"10.1016\/j.jad.2021.02.004_bib0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.psychres.2016.05.007","article-title":"Borderline personality features in depressed or anxious patients","author":"Distel","year":"2016","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.jad.2021.02.004_bib0031","doi-asserted-by":"crossref","DOI":"10.1017\/S0033291718001423","article-title":"A 6-year longitudinal study of predictors for suicide attempts in major depressive disorder","author":"Eikelenboom","year":"2019","journal-title":"Psychol. Med."},{"key":"10.1016\/j.jad.2021.02.004_bib0032","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpsychires.2012.01.025","article-title":"Do depression and anxiety converge or diverge in their association with suicidality?","author":"Eikelenboom","year":"2012","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.jad.2021.02.004_bib0033","doi-asserted-by":"crossref","DOI":"10.1111\/j.1600-0447.1993.tb03362.x","article-title":"Staging: a neglected dimension in psychiatric classification","author":"Fava","year":"1993","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.jad.2021.02.004_bib0034","doi-asserted-by":"crossref","DOI":"10.1016\/S0010-440X(00)90140-8","article-title":"Anxiety disorders in major depression","author":"Fava","year":"2000","journal-title":"Compr. Psychiatry."},{"key":"10.1016\/j.jad.2021.02.004_bib0035","doi-asserted-by":"crossref","DOI":"10.1017\/S0033291715000215","article-title":"Familiality and SNP heritability of age at onset and episodicity in major depressive disorder","author":"Ferentinos","year":"2015","journal-title":"Psychol. Med."},{"key":"10.1016\/j.jad.2021.02.004_bib0036","doi-asserted-by":"crossref","DOI":"10.1111\/j.1600-0447.2009.01512.x","article-title":"Twenty-five-year course and outcome in anxiety and depression in the upper bavarian longitudinal community study","author":"Fichter","year":"2010","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.jad.2021.02.004_bib0037","doi-asserted-by":"crossref","DOI":"10.1002\/da.22519","article-title":"Treatment and prevention of depression and anxiety in youth: test of cross-over effects","author":"Garber","year":"2016","journal-title":"Depress. Anxiety"},{"key":"10.1016\/j.jad.2021.02.004_bib0038","doi-asserted-by":"crossref","DOI":"10.4088\/JCP.15m10221","article-title":"Longitudinal predictive validity of the DSM-5 anxious distress specifier for clinical outcomes in a large cohort of patients with major depressive disorder","author":"Gaspersz","year":"2017","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0039","doi-asserted-by":"crossref","DOI":"10.1016\/j.pain.2014.05.007","article-title":"Basal inflammation and innate immune response in chronic multisite musculoskeletal pain","author":"Generaal","year":"2014","journal-title":"Pain"},{"key":"10.1016\/j.jad.2021.02.004_bib0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.pain.2011.11.001","article-title":"Impact of pain on the course of depressive and anxiety disorders","author":"Gerrits","year":"2012","journal-title":"Pain"},{"key":"10.1016\/j.jad.2021.02.004_bib0041","doi-asserted-by":"crossref","DOI":"10.1016\/j.psyneuen.2018.11.019","article-title":"Long-term glucocorticoid levels measured in hair in patients with depressive and anxiety disorders","author":"Gerritsen","year":"2019","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.jad.2021.02.004_bib0042","doi-asserted-by":"crossref","DOI":"10.4088\/JCP.14m09658","article-title":"Major depressive disorder, antidepressant use, and subsequent 2-year weight change patterns in the netherlands study of depression and anxiety","author":"Gibson-Smith","year":"2016","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0043","doi-asserted-by":"crossref","first-page":"7736","DOI":"10.3390\/ijerph17217736","article-title":"Randomized clinical trial of an internet-based adolescent depression prevention intervention in primary care: internalizing symptom outcomes","volume":"17","author":"Gladstone","year":"2020","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.jad.2021.02.004_bib0044","doi-asserted-by":"crossref","DOI":"10.1002\/(SICI)1520-6394(1996)4:4<160::AID-DA2>3.0.CO;2-J","article-title":"Comorbid depression and anxiety spectrum disorders","author":"Gorman","year":"1996","journal-title":"Depress. Anxiety"},{"key":"10.1016\/j.jad.2021.02.004_bib0045","doi-asserted-by":"crossref","DOI":"10.3389\/fnhum.2013.00523","article-title":"Reappraising social emotions: the role of inferior frontal gyrus, temporo-parietal junction and insula in interpersonal emotion regulation","author":"Grecucci","year":"2013","journal-title":"Front. Hum. Neurosci."},{"issue":"3","key":"10.1016\/j.jad.2021.02.004_bib0138","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0899-3467(07)60142-6","article-title":"Writing narrative literature reviews for peer-reviewed journals: secrets of the trade.","volume":"5","author":"Green","year":"2006","journal-title":"J Chiropr Med."},{"key":"10.1016\/j.jad.2021.02.004_bib0046","doi-asserted-by":"crossref","DOI":"10.1186\/s12916-020-01738-z","article-title":"Comorbidity between depression and anxiety: Assessing the role of bridge mental states in dynamic psychological networks","author":"Groen","year":"2020","journal-title":"BMC Med."},{"key":"10.1016\/j.jad.2021.02.004_bib0047","doi-asserted-by":"crossref","DOI":"10.1016\/j.jad.2015.03.004","article-title":"Long-term work disability and absenteeism in anxiety and depressive disorders","author":"Hendriks","year":"2015","journal-title":"J. Affect. Disord."},{"issue":"5","key":"10.1016\/j.jad.2021.02.004_bib0141","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1159\/000140085","article-title":"Early identification and intervention in depressive disorders: towards a clinical staging model","volume":"77","author":"Hetrick","year":"2008","journal-title":"Psychother Psychosom."},{"key":"10.1016\/j.jad.2021.02.004_bib0048","doi-asserted-by":"crossref","DOI":"10.1177\/0706743717711170","article-title":"Presence and predictive value of obsessive-compulsive symptoms in anxiety and depressive disorders","author":"Hofmeijer-Sevink","year":"2018","journal-title":"Can. J. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0049","doi-asserted-by":"crossref","DOI":"10.1016\/j.jad.2015.10.035","article-title":"Low stability of diagnostic classifications of anxiety disorders over time: a six-year follow-up of the NESDA study","author":"Hovenkamp-Hermelink","year":"2016","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2021.02.004_bib0050","doi-asserted-by":"crossref","DOI":"10.4088\/JCP.14m09135","article-title":"Impact of childhood life events and childhood trauma on the onset and recurrence of depressive and anxiety disorders","author":"Hovens","year":"2015","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0051","article-title":"Emotional scars: impact of childhood trauma on the development of depressive and anxiety disorders later in life","author":"Hovens","year":"2017","journal-title":"Tijdschr. Psychiatr."},{"key":"10.1016\/j.jad.2021.02.004_bib0052","doi-asserted-by":"crossref","DOI":"10.1111\/j.1600-0447.2011.01828.x","article-title":"Impact of childhood life events and trauma on the course of depressive and anxiety disorders","author":"Hovens","year":"2012","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.jad.2021.02.004_bib0053","doi-asserted-by":"crossref","DOI":"10.1111\/j.1600-0447.2009.01491.x","article-title":"Childhood life events and childhood trauma in adult patients with depressive, anxiety and comorbid disorders vs. controls","author":"Hovens","year":"2010","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.jad.2021.02.004_bib0054","doi-asserted-by":"crossref","DOI":"10.1017\/S0033291719001612","article-title":"Long-term disability in major depressive disorder: a 6-year follow-up study","author":"Iancu","year":"2020","journal-title":"Psychol. Med."},{"key":"10.1016\/j.jad.2021.02.004_bib0055","doi-asserted-by":"crossref","DOI":"10.1001\/jamapsychiatry.2013.1957","article-title":"Overt irritability\/anger in unipolar major depressive episodes: past and current characteristics and implications for long-term course","author":"Judd","year":"2013","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0056","doi-asserted-by":"crossref","DOI":"10.1192\/bjp.bp.110.080572","article-title":"Psychiatric history and subthreshold symptoms as predictors of the occurrence of depressive or anxiety disorder within 2 years","author":"Karsten","year":"2011","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0057","doi-asserted-by":"crossref","DOI":"10.1001\/jamapsychiatry.2019.1200","article-title":"From many to one to many - the search for causes of psychiatric illness","author":"Kendler","year":"2019","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0058","doi-asserted-by":"crossref","DOI":"10.1017\/S0033291706009135","article-title":"The sources of co-morbidity between major depression and generalized anxiety disorder in a Swedish national twin sample","author":"Kendler","year":"2007","journal-title":"Psychol. Med."},{"key":"10.1016\/j.jad.2021.02.004_bib0059","doi-asserted-by":"crossref","DOI":"10.1001\/jama.289.23.3095","article-title":"The epidemiology of major depressive disorder: results from the national comorbidity survey replication (NCS-R)","author":"Kessler","year":"2003","journal-title":"J. Am. Med. Assoc."},{"key":"10.1016\/j.jad.2021.02.004_bib0060","doi-asserted-by":"crossref","DOI":"10.1001\/archpsyc.1994.03950010008002","article-title":"Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States: results from the national comorbidity survey","author":"Kessler","year":"1994","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0061","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbtep.2012.05.008","article-title":"Cognitive vulnerability to comorbidity: looming cognitive style and depressive cognitive style as synergistic predictors of anxiety and depression symptoms","author":"Kleiman","year":"2012","journal-title":"J. Behav. Ther. Exp. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0062","doi-asserted-by":"crossref","DOI":"10.1016\/j.jad.2011.12.008","article-title":"Clinical relevance of comorbidity in anxiety disorders: a report from the Netherlands Study of Depression and Anxiety (NESDA)","author":"Klein Hofmeijer-Sevink","year":"2012","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2021.02.004_bib0063","doi-asserted-by":"crossref","DOI":"10.1186\/s40359-017-0179-y","article-title":"The impact of conscientiousness, mastery, and work circumstances on subsequent absenteeism in employees with and without affective disorders","author":"Kok","year":"2017","journal-title":"BMC Psychol."},{"key":"10.1016\/j.jad.2021.02.004_bib0064","doi-asserted-by":"crossref","DOI":"10.7326\/0003-4819-146-5-200703060-00004","article-title":"Anxiety disorders in primary care: prevalence, impairment, comorbidity, and detection","author":"Kroenke","year":"2007","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.jad.2021.02.004_bib0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.psychres.2011.07.005","article-title":"One-year severity of depressive symptoms: results from the NESDA study","author":"Lamers","year":"2011","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.jad.2021.02.004_bib0066","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.comppsych.2011.01.011","article-title":"Sociodemographic and psychiatric determinants of attrition in the Netherlands Study of Depression and Anxiety (NESDA)","volume":"53","author":"Lamers","year":"2012","journal-title":"Compr. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0067","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopsych.2018.12.020","article-title":"Longitudinal association between depression and inflammatory markers: results from the Netherlands study of depression and anxiety","author":"Lamers","year":"2019","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0068","doi-asserted-by":"crossref","DOI":"10.4088\/JCP.10m06176blu","article-title":"Comorbidity patterns of anxiety and depressive disorders in a large cohort study: the Netherlands Study of Depression and Anxiety (NESDA)","author":"Lamers","year":"2011","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0069","doi-asserted-by":"crossref","DOI":"10.1007\/s10926-015-9588-z","article-title":"Longitudinal associations between biopsychosocial factors and sustainable return to work of sick-listed workers with a depressive or anxiety disorder","author":"Lammerts","year":"2016","journal-title":"J. Occup. Rehabil."},{"key":"10.1016\/j.jad.2021.02.004_bib0070","doi-asserted-by":"crossref","DOI":"10.1097\/PSY.0b013e3181a292a6","article-title":"Association between anxiety disorders and heart rate variability in the Netherlands study of depression and anxiety (NESDA)","author":"Licht","year":"2009","journal-title":"Psychosom. Med."},{"key":"10.1016\/j.jad.2021.02.004_bib0071","doi-asserted-by":"crossref","DOI":"10.1001\/archpsyc.65.12.1358","article-title":"Association between major depressive disorder and heart rate variability in the Netherlands study of depression and anxiety (NESDA)","author":"Licht","year":"2008","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0072","doi-asserted-by":"crossref","DOI":"10.1038\/npp.2012.107","article-title":"Effects of antidepressants, but not psychopathology, on cardiac sympathetic control: a longitudinal study","author":"Licht","year":"2012","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.jad.2021.02.004_bib0073","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpain.2012.12.006","article-title":"Anxiety and depression are associated with migraine and pain in general: an investigation of the interrelationships","author":"Ligthart","year":"2013","journal-title":"J. Pain"},{"key":"10.1016\/j.jad.2021.02.004_bib0074","article-title":"The life chart interview: a standardized method to describe the course of psychopathology","author":"Lyketsos","year":"1994","journal-title":"Int. J. Methods Psychiatr. Res."},{"key":"10.1016\/j.jad.2021.02.004_bib0075","doi-asserted-by":"crossref","DOI":"10.1007\/s12640-018-9906-2","article-title":"Generalized Anxiety Disorder (GAD) and Comorbid Major Depression with GAD are characterized by enhanced nitro-oxidative stress, increased lipid peroxidation, and lowered lipid-associated antioxidant defenses","author":"Maes","year":"2018","journal-title":"Neurotox. Res."},{"key":"10.1016\/j.jad.2021.02.004_bib0076","doi-asserted-by":"crossref","DOI":"10.1192\/bjp.186.3.182","article-title":"Psychiatric comorbidity\u201d: an artefact of current diagnostic systems?","author":"Maj","year":"2005","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0077","doi-asserted-by":"crossref","DOI":"10.1016\/0005-7967(79)90041-X","article-title":"Brief standard self-rating for phobic patients","author":"Marks","year":"1979","journal-title":"Behav. Res. Ther."},{"key":"10.1016\/j.jad.2021.02.004_bib0078","doi-asserted-by":"crossref","DOI":"10.1007\/BF02190407","article-title":"Comorbidity and social phobia: evidence from clinical, epidemiologic, and genetic studies","author":"Merikangas","year":"1995","journal-title":"Eur. Arch. Psychiatry Clin. Neurosci."},{"key":"10.1016\/j.jad.2021.02.004_bib0079","doi-asserted-by":"crossref","DOI":"10.1038\/mp.2013.36","article-title":"The association between low vitamin D and depressive disorders","author":"Milaneschi","year":"2014","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0080","doi-asserted-by":"crossref","DOI":"10.1001\/archpsyc.64.6.651","article-title":"Depression and generalized anxiety disorder","author":"Moffitt","year":"2007","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0081","doi-asserted-by":"crossref","DOI":"10.1038\/mp.2010.98","article-title":"Serum levels of brain-derived neurotrophic factor in major depressive disorder: state-trait issues, clinical features and pharmacological treatment","author":"Molendijk","year":"2011","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0082","doi-asserted-by":"crossref","DOI":"10.3109\/15622975.2011.587892","article-title":"Gender specific associations of serum levels of brain-derived neurotrophic factor in anxiety","author":"Molendijk","year":"2012","journal-title":"World J. Biol. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0083","doi-asserted-by":"crossref","DOI":"10.1080\/15622975.2016.1273550","article-title":"Telomere length in psychiatric disorders: is it more than an ageing marker?","author":"Monroy-Jaramillo","year":"2018","journal-title":"World J. Biol. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0084","doi-asserted-by":"crossref","DOI":"10.1016\/j.cpr.2015.06.002","article-title":"Systematic review and meta-analysis of transdiagnostic psychological treatments for anxiety and depressive disorders in adulthood","author":"Newby","year":"2015","journal-title":"Clin. Psychol. Rev."},{"key":"10.1016\/j.jad.2021.02.004_bib0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.janxdis.2008.03.005","article-title":"Quality of life and anxiety and depressive disorder comorbidity","author":"Norberg","year":"2008","journal-title":"J. Anxiety Disord."},{"key":"10.1016\/j.jad.2021.02.004_bib0086","doi-asserted-by":"crossref","DOI":"10.1016\/j.euroneuro.2015.08.002","article-title":"Investigating distinct and common abnormalities of resting-state functional connectivity in depression, anxiety, and their comorbid states","author":"Pannekoek","year":"2015","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.jad.2021.02.004_bib0087","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1002\/mpr.256","article-title":"The Netherlands Study of Depression and Anxiety (NESDA): rationale, objectives and methods","volume":"17","author":"Penninx","year":"2008","journal-title":"Int. J. Methods Psychiatr. Res."},{"key":"10.1016\/j.jad.2021.02.004_bib0088","doi-asserted-by":"crossref","DOI":"10.1016\/j.jad.2011.03.027","article-title":"Two-year course of depressive and anxiety disorders: results from the Netherlands Study of Depression and Anxiety (NESDA)","author":"Penninx","year":"2011","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2021.02.004_bib0089","doi-asserted-by":"crossref","DOI":"10.1016\/j.jad.2010.01.072","article-title":"Work functioning in persons with depressive and anxiety disorders: the role of specific psychopathological characteristics","author":"Plaisier","year":"2010","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2021.02.004_bib0090","doi-asserted-by":"crossref","DOI":"10.1001\/jamapsychiatry.2018.3658","article-title":"Exploring comorbidity within mental disorders among a danish national population","author":"Plana-Ripoll","year":"2019","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0091","doi-asserted-by":"crossref","DOI":"10.1097\/01.nmd.0000217820.33841.53","article-title":"The naturalistic course of unipolar major depression in the absence of somatic therapy","author":"Posternak","year":"2006","journal-title":"J. Nerv. Ment. Dis."},{"key":"10.1016\/j.jad.2021.02.004_bib0092","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpsychires.2014.09.018","article-title":"Sleep duration, insomnia, and markers of systemic inflammation: results from the Netherlands Study of Depression and Anxiety (NESDA)","author":"Prather","year":"2015","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.jad.2021.02.004_bib0093","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroscience.2015.05.018","article-title":"The role of inflammation and microglial activation in the pathophysiology of psychiatric disorders","author":"R\u00e9us","year":"2015","journal-title":"Neuroscience"},{"key":"10.1016\/j.jad.2021.02.004_bib0094","doi-asserted-by":"crossref","DOI":"10.1111\/j.1600-0447.2011.01677.x","article-title":"The 7-year course of depression and anxiety in the general population","author":"Rhebergen","year":"2011","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.jad.2021.02.004_bib0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.cpr.2011.07.004","article-title":"Prevalence and clinical course of depression: a review","author":"Richards","year":"2011","journal-title":"Clin. Psychol. Rev."},{"key":"10.1016\/j.jad.2021.02.004_bib0096","doi-asserted-by":"crossref","DOI":"10.1192\/bjp.176.3.229","article-title":"Lifetime panic-depression comorbidity in the National Comorbidity Survey: association with symptoms, impairment, course and help-seeking","author":"Roy-Byrne","year":"2000","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0097","doi-asserted-by":"crossref","DOI":"10.1017\/S0033291700035558","article-title":"The inventory of depressive symptomatology (IDS): psychometric properties","author":"Rush","year":"1996","journal-title":"Psychol. Med."},{"key":"10.1016\/j.jad.2021.02.004_bib0098","doi-asserted-by":"crossref","DOI":"10.1111\/acps.12774","article-title":"Social functioning in patients with depressive and anxiety disorders","author":"Saris","year":"2017","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.jad.2021.02.004_bib0099","doi-asserted-by":"crossref","DOI":"10.1097\/00019442-200501000-00006","article-title":"Depression and generalized anxiety disorder: co-occurrence and longitudinal patterns in elderly patients","author":"Schoevers","year":"2005","journal-title":"Am. J. Geriatr. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0100","doi-asserted-by":"crossref","DOI":"10.1002\/gps.1001","article-title":"Comorbidity and risk-patterns of depression, generalised anxiety disorder and mixed anxiety-depression in later life: results from the AMSTEL study","author":"Schoevers","year":"2003","journal-title":"Int. J. Geriatr. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0101","doi-asserted-by":"crossref","DOI":"10.2165\/00003495-200868120-00002","article-title":"Managing the patient with co-morbid depression and an anxiety disorder","author":"Schoevers","year":"2008","journal-title":"Drugs"},{"key":"10.1016\/j.jad.2021.02.004_bib0102","doi-asserted-by":"crossref","DOI":"10.1016\/j.jad.2016.02.025","article-title":"Diagnostic instability of recurrence and the impact on recurrence rates in depressive and anxiety disorders","author":"Scholten","year":"2016","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2021.02.004_bib0103","doi-asserted-by":"crossref","DOI":"10.1016\/j.jad.2012.10.031","article-title":"Recurrence of anxiety disorders and its predictors","author":"Scholten","year":"2013","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2021.02.004_bib0104","doi-asserted-by":"crossref","DOI":"10.1192\/bjp.bp.112.110858","article-title":"Clinical staging in psychiatry: a cross-cutting model of diagnosis with heuristic and practical value","author":"Scott","year":"2013","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopsych.2010.12.034","article-title":"Depression, anxiety, and arterial stiffness","author":"Seldenrijk","year":"2011","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0106","doi-asserted-by":"crossref","DOI":"10.3109\/15622975.2011.583942","article-title":"Carotid atherosclerosis in depression and anxiety: associations for age of depression onset","author":"Seldenrijk","year":"2011","journal-title":"World J. Biol. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0107","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpsychores.2014.10.007","article-title":"Depression, anxiety and 6-year risk of cardiovascular disease","author":"Seldenrijk","year":"2015","journal-title":"J. Psychosom. Res."},{"key":"10.1016\/j.jad.2021.02.004_bib0108","doi-asserted-by":"crossref","DOI":"10.1002\/wps.20745","article-title":"Transdiagnostic clinical staging in youth mental health: a first international consensus statement","author":"Shah","year":"2020","journal-title":"World Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0109","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0139912","article-title":"Anxious or depressed and still happy?","author":"Spinhoven","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.jad.2021.02.004_bib0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.psyneuen.2012.11.015","article-title":"Hair cortisol, stress exposure, and mental health in humans: a systematic review","author":"Staufenbiel","year":"2013","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.jad.2021.02.004_bib0111","doi-asserted-by":"crossref","DOI":"10.1016\/j.psychres.2017.07.010","article-title":"Approach and avoidance tendencies in depression and anxiety disorders","author":"Struijs","year":"2017","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.jad.2021.02.004_bib0112","doi-asserted-by":"crossref","DOI":"10.1111\/acps.12753","article-title":"Duration of major and minor depressive episodes and associated risk indicators in a psychiatric epidemiological cohort study of the general population","author":"Ten Have","year":"2017","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.jad.2021.02.004_bib0113","doi-asserted-by":"crossref","DOI":"10.1016\/j.psyneuen.2017.10.005","article-title":"Omega-3 and omega-6 fatty acid levels in depressive and anxiety disorders","author":"Thesing","year":"2018","journal-title":"Psychoneuroendocrinology"},{"issue":"2","key":"10.1016\/j.jad.2021.02.004_bib0139","doi-asserted-by":"crossref","first-page":"65","DOI":"10.3109\/13814789609162146","article-title":"Comorbidity or multimorbidity: what\u2019s in a name? A review of the literature","volume":"2","author":"Van den Akker","year":"1996","journal-title":"Eur J Gen Pract"},{"key":"10.1016\/j.jad.2021.02.004_bib0114","doi-asserted-by":"crossref","DOI":"10.1016\/j.jad.2019.04.052","article-title":"Neuroticism and chronicity as predictors of 9-year course of individual depressive symptoms","author":"Van Eeden","year":"2019","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2021.02.004_bib0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.jad.2010.12.005","article-title":"Objective physical functioning in patients with depressive and\/or anxiety disorders","author":"Van Milligen","year":"2011","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2021.02.004_bib0116","doi-asserted-by":"crossref","DOI":"10.4088\/JCP.08m04865blu","article-title":"Associations between serum lipids and major depressive disorder: results from the Netherlands study of depression and anxiety (NESDA)","author":"Van Reedt Dortland","year":"2010","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0117","doi-asserted-by":"crossref","DOI":"10.1111\/j.1600-0447.2010.01565.x","article-title":"Metabolic syndrome abnormalities are associated with severity of anxiety and depression and with tricyclic antidepressant use","author":"Van Reedt Dortland","year":"2010","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.jad.2021.02.004_bib0118","doi-asserted-by":"crossref","DOI":"10.1111\/j.1600-0447.2011.01702.x","article-title":"Functional MRI correlates of visuospatial planning in out-patient depression and anxiety","author":"Van Tol","year":"2011","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.jad.2021.02.004_bib0119","doi-asserted-by":"crossref","DOI":"10.1001\/archgenpsychiatry.2010.121","article-title":"Regional brain volume in depression and anxiety disorders","author":"Van Tol","year":"2010","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0120","doi-asserted-by":"crossref","DOI":"10.1007\/s10608-018-9926-5","article-title":"Self-esteem instability in current, remitted, recovered, and comorbid depression and anxiety","author":"Van Tuijl","year":"2018","journal-title":"Cognit. Ther. Res."},{"key":"10.1016\/j.jad.2021.02.004_bib0121","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0166116","article-title":"Implicit and explicit self-esteem in current, remitted, recovered, and comorbid depression and anxiety disorders: the NESDA study","author":"Van Tuijl","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.jad.2021.02.004_bib0122","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopsych.2016.05.024","article-title":"Using clinical characteristics to identify which patients with major depressive disorder have a higher genetic load for three psychiatric disorders","author":"Verduijn","year":"2017","journal-title":"Biol. Psychiatry"},{"issue":"9","key":"10.1016\/j.jad.2021.02.004_bib0142","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.4088\/JCP.14m09272","article-title":"Clinical staging of major depressive disorder: an empirical exploration","volume":"76","author":"Verduijn","year":"2015","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0123","doi-asserted-by":"crossref","DOI":"10.1186\/s12916-017-0972-8","article-title":"Reconsidering the prognosis of major depressive disorder across diagnostic boundaries: Full recovery is the exception rather than the rule","author":"Verduijn","year":"2017","journal-title":"BMC Med."},{"key":"10.1016\/j.jad.2021.02.004_bib0124","doi-asserted-by":"crossref","DOI":"10.1192\/bjp.bp.114.151027","article-title":"Anxiety disorders and accelerated cellular ageing","author":"Verhoeven","year":"2015","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0125","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1038\/mp.2013.151","article-title":"Major depressive disorder and accelerated cellular aging: results from a large psychiatric cohort study","volume":"19","author":"Verhoeven","year":"2014","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0126","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2013.27","article-title":"Anxiety disorders and inflammation in a large adult cohort","author":"Vogelzangs","year":"2013","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0127","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2016.92","article-title":"Cytokine production capacity in depression and anxiety","author":"Vogelzangs","year":"2016","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0128","doi-asserted-by":"crossref","DOI":"10.1016\/j.jad.2010.02.112","article-title":"Cardiovascular disease in persons with depressive and anxiety disorders","author":"Vogelzangs","year":"2010","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2021.02.004_bib0129","doi-asserted-by":"crossref","DOI":"10.1016\/j.psyneuen.2012.12.017","article-title":"Salivary cortisol levels and the 2-year course of depressive and anxiety disorders","author":"Vreeburg","year":"2013","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.jad.2021.02.004_bib0130","doi-asserted-by":"crossref","DOI":"10.1001\/archgenpsychiatry.2009.50","article-title":"Major depressive disorder and hypothalamic-pituitary-adrenal axis activity: results from a large cohort study","author":"Vreeburg","year":"2009","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0131","doi-asserted-by":"crossref","DOI":"10.1097\/PSY.0b013e3181d2f0c8","article-title":"Salivary cortisol levels in persons with and without different anxiety disorders","author":"Vreeburg","year":"2010","journal-title":"Psychosom. Med."},{"key":"10.1016\/j.jad.2021.02.004_bib0132","article-title":"Delay and failure in treatment seeking after first onset of mental disorders in the World Health Organization's World Mental Health Survey Initiative","author":"Wang","year":"2007","journal-title":"World Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0140","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0022-3956(94)90036-1","article-title":"Reliability and validity studies of the WHO-Composite International Diagnostic Interview (CIDI): a critical review","volume":"28","author":"Wittchen","year":"1994","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.jad.2021.02.004_bib0133","doi-asserted-by":"crossref","DOI":"10.1038\/s41588-018-0090-3","article-title":"Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression","author":"Wray","year":"2018","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jad.2021.02.004_bib0134","doi-asserted-by":"crossref","DOI":"10.1037\/a0025079","article-title":"Stress reactivity in social anxiety disorder with and without comorbid depression","author":"Yoon","year":"2012","journal-title":"J. Abnorm. Psychol."},{"key":"10.1016\/j.jad.2021.02.004_bib0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopsych.2004.03.017","article-title":"Effect of comorbid anxiety disorders on the hypothalamic-pituitary-adrenal axis response to a social stressor in major depression","author":"Young","year":"2004","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2021.02.004_bib0136","doi-asserted-by":"crossref","DOI":"10.1016\/j.psyneuen.2016.11.036","article-title":"Cortisol stress reactivity across psychiatric disorders: a systematic review and meta-analysis","author":"Zorn","year":"2017","journal-title":"Psychoneuroendocrinology"}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032721001117?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032721001117?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T01:49:09Z","timestamp":1759024149000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165032721001117"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":142,"alternative-id":["S0165032721001117"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2021.02.004","relation":{},"ISSN":["0165-0327"],"issn-type":[{"value":"0165-0327","type":"print"}],"subject":[],"published":{"date-parts":[[2021,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Depressive and anxiety disorders in concert\u2013A synthesis of findings on comorbidity in the NESDA study","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2021.02.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}