{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:57:51Z","timestamp":1760147871753,"version":"3.44.0"},"reference-count":86,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1016\/j.jad.2021.03.008","type":"journal-article","created":{"date-parts":[[2021,3,8]],"date-time":"2021-03-08T18:30:22Z","timestamp":1615228222000},"page":"259-266","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["The interaction effect of early trauma exposure and a diagnosis of panic disorder on cortical thickness"],"prefix":"10.1016","volume":"286","author":[{"given":"Iseul","family":"An","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minji","family":"Bang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7939-3000","authenticated-orcid":false,"given":"Sang-Hyuk","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jad.2021.03.008_bib0001","series-title":"Stress-Induced and Fear Circuitry Disorders: Refining the Research Agenda for DSM-V","first-page":"159","article-title":"Serotonin, Sensitive Periods, and Anxiety","author":"Alter","year":"2009"},{"year":"2000","series-title":"Diagnostic Criteria from DSM-IV-TR","key":"10.1016\/j.jad.2021.03.008_bib0002"},{"key":"10.1016\/j.jad.2021.03.008_bib0003","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.janxdis.2007.02.004","article-title":"Emotion regulation and anxiety disorders","volume":"22","author":"Amstadter","year":"2008","journal-title":"J. Anxiety Disord."},{"key":"10.1016\/j.jad.2021.03.008_bib0004","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.jad.2018.07.064","article-title":"Cortical thickness reductions in the middle frontal cortex in patients with panic disorder","volume":"240","author":"Asami","year":"2018","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2021.03.008_bib0005","doi-asserted-by":"crossref","first-page":"7783","DOI":"10.1523\/JNEUROSCI.16-23-07783.1996","article-title":"Early and later adoptions have different long-term effects on male rat offspring","volume":"16","author":"Barbazanges","year":"1996","journal-title":"J. Neurosci."},{"year":"1996","series-title":"Beck Depression Inventory (BDI-II)","author":"Beck","key":"10.1016\/j.jad.2021.03.008_bib0006"},{"issue":"2","key":"10.1016\/j.jad.2021.03.008_bib0007","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/S0006-3223(02)01355-0","article-title":"rCBF differences between panic disorder patients and control subjects during anticipatory anxiety and rest","volume":"52","author":"Boshuisen","year":"2002","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2021.03.008_bib0008","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0006-3223(96)00162-X","article-title":"Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse\u2013a preliminary report","volume":"41","author":"Bremner","year":"1997","journal-title":"Biol. psychiatry"},{"issue":"4","key":"10.1016\/j.jad.2021.03.008_bib0009","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1002\/ana.410220408","article-title":"Positron emission tomography study of human brain functional development","volume":"22","author":"Chugani","year":"1987","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.jad.2021.03.008_bib0010","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1017\/S0033291712001390","article-title":"Differential functional connectivity within an emotion regulation neural network among individuals resilient and susceptible to the depressogenic effects of early life stress","volume":"43","author":"Cisler","year":"2013","journal-title":"Psychol. Med."},{"issue":"2","key":"10.1016\/j.jad.2021.03.008_bib0011","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1038\/nn1176","article-title":"Neural systems supporting interoceptive awareness","volume":"7","author":"Critchley","year":"2004","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.jad.2021.03.008_bib0012","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.biopsych.2011.10.021","article-title":"Limbic scars: long-term consequences of childhood maltreatment revealed by functional and structural magnetic resonance imaging","volume":"71","author":"Dannlowski","year":"2012","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2021.03.008_bib0013","unstructured":"De Bellis, M.D., Hooper, S.R., Sapia, J.L., 2005. Early trauma exposure and the brain."},{"key":"10.1016\/j.jad.2021.03.008_bib0014","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1016\/S0006-3223(02)01459-2","article-title":"Brain structures in pediatric maltreatment-related posttraumatic stress disorder: a sociodemographically matched study","volume":"52","author":"De Bellis","year":"2002","journal-title":"Biol. Psychiatry"},{"issue":"3","key":"10.1016\/j.jad.2021.03.008_bib0015","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1016\/j.neuroimage.2006.01.021","article-title":"An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest","volume":"31","author":"Desikan","year":"2006","journal-title":"Neuroimage"},{"key":"10.1016\/j.jad.2021.03.008_bib0016","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1001\/archpediatrics.2011.565","article-title":"Corticostriatal-limbic gray matter morphology in adolescents with self-reported exposure to childhood maltreatment","volume":"165","author":"Edmiston","year":"2011","journal-title":"Arch. Pediatr. Adolesc. Med."},{"issue":"1","key":"10.1016\/j.jad.2021.03.008_bib0017","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1093\/eurpub\/cki114","article-title":"Childhood adversities and health variations among middle-aged men: a retrospective lifecourse study","volume":"15","author":"Elstad","year":"2005","journal-title":"Eur. J. Public Health"},{"issue":"6","key":"10.1016\/j.jad.2021.03.008_bib0018","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1007\/s00406-015-0653-6","article-title":"Functional MRI activation in response to panic-specific, non-panic aversive, and neutral pictures in patients with panic disorder and healthy controls","volume":"266","author":"Engel","year":"2016","journal-title":"Eur. Arch. Psychiatry. Clin. Neurosci."},{"key":"10.1016\/j.jad.2021.03.008_bib0019","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1093\/cercor\/bhr385","article-title":"Attentional modulation of primary interoceptive and exteroceptive cortices","volume":"23","author":"Farb","year":"2013","journal-title":"Cereb. Cortex"},{"issue":"2","key":"10.1016\/j.jad.2021.03.008_bib0020","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1891\/jcop.20.2.201","article-title":"Anxiety sensitivity as a moderator of the relation between trauma exposure frequency and posttraumatic stress symptomatology","volume":"20","author":"Feldner","year":"2006","journal-title":"J. Cognit. Psychother."},{"key":"10.1016\/j.jad.2021.03.008_bib0021","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1017\/S0033291799002111","article-title":"The stability of child abuse reports: a longitudinal study of the reporting behaviour of young adults","volume":"30","author":"Fergusson","year":"2000","journal-title":"Psychol. Med."},{"key":"10.1016\/j.jad.2021.03.008_bib0022","series-title":"Structured Clinical Interview for DSM-IV-TR Axis I Disorders, research version","article-title":"Structured Clinical Interview for DSM-IV-TR Axis I Disorders","author":"First","year":"2002"},{"key":"10.1016\/j.jad.2021.03.008_bib0023","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1093\/cercor\/bhg087","article-title":"Automatically parcellating the human cerebral cortex","volume":"14","author":"Fischl","year":"2004","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.jad.2021.03.008_bib0024","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1159\/000119738","article-title":"Alexithymia and cognitive dysfunctions in patients with panic disorder","volume":"77","author":"Galderisi","year":"2008","journal-title":"Psychother. Psychosom."},{"issue":"4","key":"10.1016\/j.jad.2021.03.008_bib0025","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1093\/cercor\/6.4.551","article-title":"Quantitative magnetic resonance imaging of human brain development: ages 4\u201318","volume":"6","author":"Giedd","year":"1996","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.jad.2021.03.008_bib0026","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1038\/nn958","article-title":"Smaller hippocampal volume predicts pathologic vulnerability to psychological trauma","volume":"5","author":"Gilbertson","year":"2002","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.jad.2021.03.008_bib0027","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1111\/jcpp.12630","article-title":"Childhood abuse and reduced cortical thickness in brain regions involved in emotional processing","volume":"57","author":"Gold","year":"2016","journal-title":"J. Child Psychol. Psychiatry"},{"key":"10.1016\/j.jad.2021.03.008_bib0028","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1016\/j.neuroimage.2011.08.017","article-title":"Convergence and divergence of thickness correlations with diffusion connections across the human cerebral cortex","volume":"59","author":"Gong","year":"2012","journal-title":"Neuroimage"},{"key":"10.1016\/j.jad.2021.03.008_bib0029","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1017\/S0033291704003265","article-title":"Childhood abuse and familial violence and the risk of panic attacks and panic disorder in young adulthood","volume":"35","author":"Goodwin","year":"2005","journal-title":"J. Psychol. Med."},{"key":"10.1016\/j.jad.2021.03.008_bib0030","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1177\/2167702614536164","article-title":"Emotion, emotion regulation, and psychopathology: an affective science perspective","volume":"2","author":"Gross","year":"2014","journal-title":"J. Clin. Psychol. Sci."},{"key":"10.1016\/j.jad.2021.03.008_bib0031","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/j.neuroimage.2006.07.036","article-title":"Smoothing and cluster thresholding for cortical surface-based group analysis of fMRI data","volume":"33","author":"Hagler","year":"2006","journal-title":"J NeuroImage"},{"key":"10.1016\/j.jad.2021.03.008_bib0032","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1038\/sj.npp.1300311","article-title":"Evidence for genetic linkage between a polymorphism in the adenosine 2A receptor and panic disorder","volume":"29","author":"Hamilton","year":"2004","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.jad.2021.03.008_bib0033","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.biopsych.2009.03.007","article-title":"Neural origins of human sickness in interoceptive responses to inflammation","volume":"66","author":"Harrison","year":"2009","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2021.03.008_bib0034","doi-asserted-by":"crossref","first-page":"52","DOI":"10.3389\/fnhum.2012.00052","article-title":"Neuroimaging of child abuse: a critical review","volume":"6","author":"Hart","year":"2012","journal-title":"Front. Hum. Neurosci."},{"key":"10.1016\/j.jad.2021.03.008_bib0036","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1007\/s10608-015-9735-z","article-title":"Childhood maltreatment exposure and disruptions in emotion regulation: a transdiagnostic pathway to adolescent internalizing and externalizing psychopathology","volume":"40","author":"Heleniak","year":"2016","journal-title":"Cognit. Ther. Res."},{"key":"10.1016\/j.jad.2021.03.008_bib0037","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1176\/appi.ajp.158.10.1568","article-title":"A review and meta-analysis of the genetic epidemiology of anxiety disorders","volume":"158","author":"Hettema","year":"2001","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.jad.2021.03.008_bib0038","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.neuroimage.2009.06.043","article-title":"A comparison between voxel-based cortical thickness and voxel-based morphometry in normal aging","volume":"48","author":"Hutton","year":"2009","journal-title":"J. Neuroimage."},{"key":"10.1016\/j.jad.2021.03.008_bib0039","doi-asserted-by":"crossref","first-page":"229","DOI":"10.4306\/pi.2012.9.3.229","article-title":"The early trauma inventory self report-short form: psychometric properties of the korean version","volume":"9","author":"Jeon","year":"2012","journal-title":"Psychiatry Investig."},{"key":"10.1016\/j.jad.2021.03.008_bib0040","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.3349\/ymj.2017.58.5.1018","article-title":"Reduced cortical thickness in the temporal pole, insula, and pars triangularis in patients with panic disorder","volume":"58","author":"Kang","year":"2017","journal-title":"Yonsei Med. J."},{"issue":"4","key":"10.1016\/j.jad.2021.03.008_bib0041","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1007\/s11682-014-9330-z","article-title":"Inflammation as a mediator of the relationship between cortical thickness and metabolic syndrome","volume":"9","author":"Kaur","year":"2015","journal-title":"Brain Imaging Behav."},{"issue":"1","key":"10.1016\/j.jad.2021.03.008_bib0042","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0887-6185(96)00034-5","article-title":"The phenomenology of panic disorder in youngsters: an empirical study of a clinical sample","volume":"11","author":"Kearney","year":"1997","journal-title":"J. Anxiety Disord."},{"key":"10.1016\/j.jad.2021.03.008_bib0043","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1192\/bjp.bp.110.080499","article-title":"Childhood adversities and adult psychopathology in the WHO World Mental Health Surveys","volume":"197","author":"Kessler","year":"2010","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.jad.2021.03.008_bib0044","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.jad.2020.02.019","article-title":"Early sexual trauma is related with the tapetum in patients with panic disorder","volume":"267","author":"Kim","year":"2020","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2021.03.008_bib0045","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.jad.2016.08.043","article-title":"White matter correlates of anxiety sensitivity in panic disorder","volume":"207","author":"Kim","year":"2017","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2021.03.008_bib0046","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1002\/da.20667","article-title":"Life events in panic disorder\u2014an update on \u201ccandidate stressors\u201d","volume":"27","author":"Klauke","year":"2010","journal-title":"Depress Anxiety"},{"issue":"8","key":"10.1016\/j.jad.2021.03.008_bib0047","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1162\/0898929042304796","article-title":"Sensitive periods in the development of the brain and behavior","volume":"16","author":"Knudsen","year":"2004","journal-title":"J. Cogn. Neurosci."},{"issue":"2","key":"10.1016\/j.jad.2021.03.008_bib0048","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1503\/jpn.100167","article-title":"Working memory processing of traumatic material in women with posttraumatic stress disorder","volume":"37","author":"Landr\u00e9","year":"2012","journal-title":"J. Psychiatry Neurosci."},{"key":"10.1016\/j.jad.2021.03.008_bib0049","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1016\/S0006-3223(98)00282-0","article-title":"Fear and the brain: where have we been, and where are we going?","volume":"44","author":"LeDoux","year":"1998","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2021.03.008_bib0050","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1111\/j.1471-4159.2004.02420.x","article-title":"Pro-regenerative properties of cytokine-activated astrocytes","volume":"89","author":"Liberto","year":"2004","journal-title":"J. Neurochem."},{"key":"10.1016\/j.jad.2021.03.008_bib0051","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1017\/S0033291717002392","article-title":"Grey matter volume and thickness abnormalities in young people with a history of childhood abuse","volume":"48","author":"Lim","year":"2018","journal-title":"Psychol. Med."},{"key":"10.1016\/j.jad.2021.03.008_bib0053","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1176\/appi.ajp.2014.13101427","article-title":"Gray matter abnormalities in childhood maltreatment: a voxel-wise meta-analysis","volume":"171","author":"Lim","year":"2014","journal-title":"Am. J Psychiatry"},{"key":"10.1016\/j.jad.2021.03.008_bib0055","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1002\/da.20210","article-title":"Korean Anxiety Sensitivity Index-Revised: its factor structure, reliability, and validity in clinical and nonclinical samples","volume":"24","author":"Lim","year":"2007","journal-title":"Depress Anxiety"},{"key":"10.1016\/j.jad.2021.03.008_bib0056","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1523\/JNEUROSCI.15-01-00110.1995","article-title":"Adoption reverses the long-term impairment in glucocorticoid feedback induced by prenatal stress","volume":"15","author":"Maccari","year":"1995","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jad.2021.03.008_bib0057","doi-asserted-by":"crossref","first-page":"48","DOI":"10.3389\/fpsyt.2011.00048","article-title":"The impact of childhood maltreatment: a review of neurobiological and genetic factors","volume":"2","author":"McCrory","year":"2011","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.jad.2021.03.008_bib0058","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1111\/j.1469-7610.2010.02271.x","article-title":"Research review: the neurobiology and genetics of maltreatment and adversity","volume":"51","author":"McCrory","year":"2010","journal-title":"J. Child Psychol Psychiatry"},{"key":"10.1016\/j.jad.2021.03.008_bib0059","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1002\/da.22084","article-title":"Cytokine targets in the brain: impact on neurotransmitters and neurocircuits","volume":"30","author":"Miller","year":"2013","journal-title":"Depress Anxiety"},{"key":"10.1016\/j.jad.2021.03.008_bib0060","doi-asserted-by":"crossref","first-page":"753","DOI":"10.2105\/AJPH.91.5.753","article-title":"Child sexual abuse and subsequent psychopathology: results from the National Comorbidity Survey","volume":"91","author":"Molnar","year":"2001","journal-title":"Am. J. Public Health"},{"key":"10.1016\/j.jad.2021.03.008_bib0061","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1093\/cercor\/bhh172","article-title":"Mapping cortical thickness and gray matter concentration in first episode schizophrenia","volume":"15","author":"Narr","year":"2005","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.jad.2021.03.008_bib0062","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.neuroimage.2005.06.068","article-title":"Functional neuroanatomy of aversion and its anticipation","volume":"29","author":"Nitschke","year":"2006","journal-title":"Neuroimage"},{"key":"10.1016\/j.jad.2021.03.008_bib0063","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1016\/S1053-8119(03)00251-9","article-title":"Increased activation in the right insula during risk-taking decision making is related to harm avoidance and neuroticism","volume":"19","author":"Paulus","year":"2003","journal-title":"J. Neuroimage"},{"key":"10.1016\/j.jad.2021.03.008_bib0064","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.biopsych.2006.03.042","article-title":"An insular view of anxiety","volume":"60","author":"Paulus","year":"2006","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2021.03.008_bib0066","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.pscychresns.2015.05.013","article-title":"Neural correlates of anxiety sensitivity in panic disorder: a functional magnetic resonance imaging study","volume":"233","author":"Poletti","year":"2015","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.jad.2021.03.008_bib0067","doi-asserted-by":"crossref","first-page":"e378","DOI":"10.1038\/tp.2014.18","article-title":"Regional increases of cortical thickness in untreated, first-episode major depressive disorder","volume":"4","author":"Qiu","year":"2014","journal-title":"Transl. Psychiatry"},{"issue":"3","key":"10.1016\/j.jad.2021.03.008_bib0069","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1023\/A:1010783427196","article-title":"Interpretation of ambiguous interoceptive stimuli in panic disorder and nonclinical panic","volume":"25","author":"Richards","year":"2001","journal-title":"Cognit. Ther. Res."},{"key":"10.1016\/j.jad.2021.03.008_bib0070","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.paid.2018.12.029","article-title":"Psychological flexibility as a mediator of the association between early life trauma and psychological symptoms","volume":"141","author":"Richardson","year":"2019","journal-title":"Pers. Individ. Dif."},{"key":"10.1016\/j.jad.2021.03.008_bib0071","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/j.biopsych.2008.11.028","article-title":"Lasting epigenetic influence of early-life adversity on the BDNF gene","volume":"65","author":"Roth","year":"2009","journal-title":"Biol. Psychiatry"},{"issue":"10","key":"10.1016\/j.jad.2021.03.008_bib0072","doi-asserted-by":"crossref","first-page":"2237","DOI":"10.1038\/sj.npp.1301048","article-title":"Association of the Val158Met catechol O-methyltransferase genetic polymorphism with panic disorder","volume":"31","author":"Rothe","year":"2006","journal-title":"Neuropsychopharmacology"},{"issue":"8","key":"10.1016\/j.jad.2021.03.008_bib0073","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1017\/S0033291702006566","article-title":"Childhood trauma and neuroticism as an adult: possible implication for the development of the common psychiatric disorders and suicidal behaviour","volume":"32","author":"Roy","year":"2002","journal-title":"Psychol. Med."},{"issue":"1","key":"10.1016\/j.jad.2021.03.008_bib0074","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.psychres.2004.05.012","article-title":"Association studies of MAO-A, COMT, and 5-HTT genes polymorphisms in patients with anxiety disorders of the phobic spectrum","volume":"128","author":"Samochowiec","year":"2004","journal-title":"Psychiatry Res."},{"issue":"3","key":"10.1016\/j.jad.2021.03.008_bib0075","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1037\/0021-843X.106.3.355","article-title":"The role of anxiety sensitivity in the pathogenesis of panic: prospective evaluation of spontaneous panic attacks during acute stress","volume":"106","author":"Schmidt","year":"1997","journal-title":"J. Abnorm. Psychol."},{"key":"10.1016\/j.jad.2021.03.008_bib0076","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/j.jesp.2004.04.005","article-title":"The role of neuroticism on psychological and physiological stress responses","volume":"40","author":"Schneider","year":"2004","journal-title":"J. Exp. Soc. Psychol."},{"key":"10.1016\/j.jad.2021.03.008_bib0077","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1176\/ajp.154.11.1571","article-title":"Multicenter collaborative panic disorder severity scale","volume":"154","author":"Shear","year":"1997","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.jad.2021.03.008_bib0078","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.schres.2012.10.032","article-title":"Reduced gray matter volume in psychotic disorder patients with a history of childhood sexual abuse","volume":"143","author":"Sheffield","year":"2013","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.jad.2021.03.008_bib0079","doi-asserted-by":"crossref","first-page":"2944","DOI":"10.1002\/hbm.22113","article-title":"Keeping the body in mind: insula functional organization and functional connectivity integrate interoceptive, exteroceptive, and emotional awareness","volume":"34","author":"Simmons","year":"2013","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.jad.2021.03.008_bib0080","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1016\/j.chiabu.2003.05.001","article-title":"Childhood emotional abuse and neglect as predictors of psychological and physical symptoms in women presenting to a primary care practice","volume":"27","author":"Spertus","year":"2003","journal-title":"Child Abuse Neglect"},{"key":"10.1016\/j.jad.2021.03.008_bib0081","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1080\/13554790903066909","article-title":"Cerebral correlates of heart rate variations during a spontaneous panic attack in the fMRI scanner","volume":"15","author":"Spiegelhalder","year":"2009","journal-title":"Neurocase"},{"key":"10.1016\/j.jad.2021.03.008_bib0082","unstructured":"Steer, R.A., Beck, A.T., 1997. Beck anxiety inventory."},{"key":"10.1016\/j.jad.2021.03.008_bib0083","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1017\/S0033291797005242","article-title":"Hippocampal volume in women victimized by childhood sexual abuse","volume":"27","author":"Stein","year":"1997","journal-title":"Psychol. Med."},{"key":"10.1016\/j.jad.2021.03.008_bib0084","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1176\/ajp.2007.164.2.318","article-title":"Increased amygdala and insula activation during emotion processing in anxiety-prone subjects","volume":"164","author":"Stein","year":"2007","journal-title":"Am. J. Psychiatry"},{"issue":"1","key":"10.1016\/j.jad.2021.03.008_bib0085","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.avb.2009.08.003","article-title":"Child maltreatment and the developing brain: a review of neuroscience perspectives","volume":"15","author":"Twardosz","year":"2010","journal-title":"Aggress. Violent Behav."},{"key":"10.1016\/j.jad.2021.03.008_bib0087","doi-asserted-by":"crossref","first-page":"2072","DOI":"10.1176\/appi.ajp.159.12.2072","article-title":"Childhood trauma associated with smaller hippocampal volume in women with major depression","volume":"159","author":"Vythilingam","year":"2002","journal-title":"Am. J. Psychiatry"},{"issue":"5","key":"10.1016\/j.jad.2021.03.008_bib0088","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.comppsych.2008.03.003","article-title":"Harm avoidance and self-directedness as essential features of panic disorder patients","volume":"49","author":"Wachleski","year":"2008","journal-title":"Compr. Psychiatry"},{"key":"10.1016\/j.jad.2021.03.008_bib0089","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/S0002-9343(99)00235-1","article-title":"Adult health status of women with histories of childhood abuse and neglect","volume":"107","author":"Walker","year":"1999","journal-title":"Am. J. Med."},{"key":"10.1016\/j.jad.2021.03.008_bib0090","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1111\/j.1540-4560.2006.00484.x","article-title":"The psychobiology of maltreatment in childhood","volume":"62","author":"Watts-English","year":"2006","journal-title":"J. Soc. Issues"},{"key":"10.1016\/j.jad.2021.03.008_bib0091","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.jad.2017.05.043","article-title":"Fornix microalterations associated with early trauma in panic disorder","volume":"220","author":"Yu","year":"2017","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2021.03.008_bib0092","doi-asserted-by":"crossref","DOI":"10.1016\/j.psychres.2020.113385","article-title":"DNA methylation of IL-4 gene and the association with childhood trauma in panic disorder","volume":"293","author":"Zou","year":"2020","journal-title":"Psychiatry Res."}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032721002330?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032721002330?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T01:55:09Z","timestamp":1759024509000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165032721002330"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":86,"alternative-id":["S0165032721002330"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2021.03.008","relation":{},"ISSN":["0165-0327"],"issn-type":[{"type":"print","value":"0165-0327"}],"subject":[],"published":{"date-parts":[[2021,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The interaction effect of early trauma exposure and a diagnosis of panic disorder on cortical thickness","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2021.03.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}