{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T01:03:38Z","timestamp":1787619818685,"version":"build-2736575974"},"reference-count":74,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100010822","name":"chengdu shi kexue jishu ju","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010822","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013365","name":"Sichuan University West China Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013365","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81671669"],"award-info":[{"award-number":["81671669"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004829","name":"Department of Science and Technology of Sichuan Province","doi-asserted-by":"publisher","award":["2017JQ0001"],"award-info":[{"award-number":["2017JQ0001"]}],"id":[{"id":"10.13039\/501100004829","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1016\/j.jad.2021.11.005","type":"journal-article","created":{"date-parts":[[2021,11,5]],"date-time":"2021-11-05T16:07:02Z","timestamp":1636128422000},"page":"421-430","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"special_numbering":"PA","title":["Distinct alterations of amygdala subregional functional connectivity in early- and late-onset obsessive-compulsive disorder"],"prefix":"10.1016","volume":"298","author":[{"given":"Lingxiao","family":"Cao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hailong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyu","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingxue","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaili","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lianqing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyue","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuan","family":"Bu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanlin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiyong","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqi","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jad.2021.11.005_bib0001","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1007\/s00429-005-0025-5","article-title":"Cytoarchitectonic mapping of the human amygdala, hippocampal region and entorhinal cortex: intersubject variability and probability maps","volume":"210","author":"Amunts","year":"2005","journal-title":"Anat. Embryol."},{"key":"10.1016\/j.jad.2021.11.005_bib0002","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/j.neuroimage.2005.02.018","article-title":"Unified segmentation","volume":"26","author":"Ashburner","year":"2005","journal-title":"Neuroimage"},{"key":"10.1016\/j.jad.2021.11.005_bib0003","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1097\/00041444-200509000-00007","article-title":"A family genetic study of clinical subtypes of obsessive-compulsive disorder","volume":"15","author":"Bhattacharyya","year":"2005","journal-title":"Psychiatr. Genet."},{"key":"10.1016\/j.jad.2021.11.005_bib0004","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1176\/appi.ajp.2016.16020201","article-title":"Distinct subcortical volume alterations in pediatric and adult OCD: a worldwide meta- and mega-analysis","volume":"174","author":"Boedhoe","year":"2017","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.jad.2021.11.005_bib0005","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1038\/npp.2013.197","article-title":"Altered resting-state functional connectivity of basolateral and centromedial amygdala complexes in posttraumatic stress disorder","volume":"39","author":"Brown","year":"2014","journal-title":"Neuropsychopharmacol. Off. Publ. Am. Coll. Neuropsychopharmacol."},{"key":"10.1016\/j.jad.2021.11.005_bib0006","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1038\/s41398-020-01013-y","article-title":"Structural neuroimaging biomarkers for obsessive-compulsive disorder in the ENIGMA-OCD consortium: medication matters","volume":"10","author":"Bruin","year":"2020","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.jad.2021.11.005_bib0007","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1007\/s00787-009-0055-2","article-title":"Symptom clusters in obsessive-compulsive disorder (OCD): influence of age and age of onset","volume":"19","author":"Butwicka","year":"2010","journal-title":"Eur. Child Adolesc. Psychiatry"},{"key":"10.1016\/j.jad.2021.11.005_bib0008","doi-asserted-by":"crossref","first-page":"3247","DOI":"10.1002\/hbm.22138","article-title":"An investigation of the structural, connectional, and functional subspecialization in the human amygdala","volume":"34","author":"Bzdok","year":"2013","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.jad.2021.11.005_bib0009","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1038\/sj.npp.1301593","article-title":"Functional coupling of the amygdala in depressed patients treated with antidepressant medication","volume":"33","author":"Chen","year":"2008","journal-title":"Neuropsychopharmacol. Off. Publ. Am. Coll. Neuropsychopharmacol."},{"key":"10.1016\/j.jad.2021.11.005_bib0010","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/sj.mp.4000812","article-title":"The amygdala: vigilance and emotion","volume":"6","author":"Davis","year":"2001","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jad.2021.11.005_bib0011","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1017\/S0033291704003253","article-title":"Admixture analysis of age at onset in obsessive-compulsive disorder","volume":"35","author":"Delorme","year":"2005","journal-title":"Psychol. Med."},{"key":"10.1016\/j.jad.2021.11.005_bib0012","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1016\/j.neuroimage.2004.12.034","article-title":"A new SPM toolbox for combining probabilistic cytoarchitectonic maps and functional imaging data","volume":"25","author":"Eickhoff","year":"2005","journal-title":"Neuroimage"},{"key":"10.1016\/j.jad.2021.11.005_bib0013","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1001\/archgenpsychiatry.2009.104","article-title":"Disrupted amygdalar subregion functional connectivity and evidence of a compensatory network in generalized anxiety disorder","volume":"66","author":"Etkin","year":"2009","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.jad.2021.11.005_bib0014","doi-asserted-by":"crossref","first-page":"2400","DOI":"10.1093\/cercor\/bhl148","article-title":"Effective connectivity within the distributed cortical network for face perception","volume":"17","author":"Fairhall","year":"2007","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.jad.2021.11.005_bib0015","doi-asserted-by":"crossref","first-page":"991","DOI":"10.3758\/s13415-016-0447-y","article-title":"Emotion regulation and amygdala-precuneus connectivity: focusing on attentional deployment","volume":"16","author":"Ferri","year":"2016","journal-title":"Cogn. Affect. Behav. Neurosci."},{"key":"10.1016\/j.jad.2021.11.005_bib0016","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1038\/nrn2201","article-title":"Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging","volume":"8","author":"Fox","year":"2007","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.jad.2021.11.005_bib0017","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1002\/cne.20520","article-title":"The organization of projections from the amygdala to visual cortical areas TE and V1 in the macaque monkey","volume":"486","author":"Freese","year":"2005","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.jad.2021.11.005_bib0018","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1002\/cne.20945","article-title":"Synaptic organization of projections from the amygdala to visual cortical areas TE and V1 in the macaque monkey","volume":"496","author":"Freese","year":"2006","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.jad.2021.11.005_bib0019","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1093\/brain\/awaa100","article-title":"Deep brain stimulation modulates directional limbic connectivity in obsessive-compulsive disorder","volume":"143","author":"Fridgeirsson","year":"2020","journal-title":"Brain A J. Neurol."},{"key":"10.1016\/j.jad.2021.11.005_bib0020","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1503\/jpn.160215","article-title":"Basolateral amygdala-ventromedial prefrontal cortex connectivity predicts cognitive behavioural therapy outcome in adults with obsessive-compulsive disorder","volume":"42","author":"Fullana","year":"2017","journal-title":"J. Psychiatry Neurosci. JPN"},{"key":"10.1016\/j.jad.2021.11.005_bib0021","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1017\/S0033291705005441","article-title":"A direct interview family study of obsessive-compulsive disorder. I","volume":"35","author":"Fyer","year":"2005","journal-title":"Psychol. Med."},{"key":"10.1016\/j.jad.2021.11.005_bib0022","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.neuroimage.2014.03.038","article-title":"The development of human amygdala functional connectivity at rest from 4 to 23 years: a cross-sectional study","volume":"95","author":"Gabard-Durnam","year":"2014","journal-title":"Neuroimage"},{"key":"10.1016\/j.jad.2021.11.005_bib0023","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.biopsych.2013.01.018","article-title":"Counterfactual processing of economic action-outcome alternatives in obsessive-compulsive disorder: further evidence of impaired goal-directed behavior","volume":"75","author":"Gillan","year":"2014","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2021.11.005_bib0024","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1002\/cne.903490105","article-title":"Visual pontocerebellar projections in the macaque","volume":"349","author":"Glickstein","year":"1994","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.jad.2021.11.005_bib0025","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/0006-8993(86)91009-7","article-title":"Classical conditioning of tone-signaled bradycardia modifies 2-deoxyglucose uptake patterns in cortex, thalamus, habenula, caudate-putamen and hippocampal formation","volume":"363","author":"Gonzalez-Lima","year":"1986","journal-title":"Brain Res."},{"key":"10.1016\/j.jad.2021.11.005_bib0026","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1001\/archpsyc.1989.01810110048007","article-title":"The Yale-Brown Obsessive Compulsive Scale. I. Development, use, and reliability","volume":"46","author":"Goodman","year":"1989","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.jad.2021.11.005_bib0027","doi-asserted-by":"crossref","first-page":"5974","DOI":"10.1002\/hbm.22598","article-title":"A direct amygdala-motor pathway for emotional displays to influence action: a diffusion tensor imaging study","volume":"35","author":"Gr\u00e8zes","year":"2014","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.jad.2021.11.005_bib0028","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1038\/npp.2009.129","article-title":"The reward circuit: linking primate anatomy and human imaging","volume":"35","author":"Haber","year":"2010","journal-title":"Neuropsychopharmacol. Off. Publ. Am. Coll. Neuropsychopharmacol."},{"key":"10.1016\/j.jad.2021.11.005_bib0029","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0006-3223(01)01330-0","article-title":"Human neural systems for face recognition and social communication","volume":"51","author":"Haxby","year":"2002","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2021.11.005_bib0030","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1111\/j.2044-8341.1959.tb00467.x","article-title":"The assessment of anxiety states by rating","volume":"32","author":"Hamilton","year":"1959","journal-title":"Br. J. Med. Psychol."},{"key":"10.1016\/j.jad.2021.11.005_bib0031","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1111\/j.2044-8260.1967.tb00530.x","article-title":"Development of a rating scale for primary depressive illness","volume":"6","author":"Hamilton","year":"1967","journal-title":"Br. J. Soc. Clin. Psychol."},{"key":"10.1016\/j.jad.2021.11.005_bib0032","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1176\/appi.ajp.158.1.137","article-title":"Is age at symptom onset associated with severity of memory impairment in adults with obsessive-compulsive disorder?","volume":"158","author":"Henin","year":"2001","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.jad.2021.11.005_bib0033","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1017\/S1461145710001604","article-title":"The serotonin transporter availability in untreated early-onset and late-onset patients with obsessive-compulsive disorder","volume":"14","author":"Hesse","year":"2011","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.jad.2021.11.005_bib0034","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.nicl.2013.06.013","article-title":"Abnormal corticostriatal-limbic functional connectivity in obsessive-compulsive disorder during reward processing and resting-state","volume":"3","author":"Jung","year":"2013","journal-title":"Neuroimage Clin."},{"key":"10.1016\/j.jad.2021.11.005_bib0035","doi-asserted-by":"crossref","first-page":"2109","DOI":"10.1098\/rstb.2006.1934","article-title":"The fusiform face area: a cortical region specialized for the perception of faces","volume":"361","author":"Kanwisher","year":"2006","journal-title":"Philos. Trans. R. Soc. Lond. B Biol. Sci."},{"key":"10.1016\/j.jad.2021.11.005_bib0036","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1002\/aur.1589","article-title":"Subregional differences in intrinsic amygdala hyperconnectivity and hypoconnectivity in autism spectrum disorder","volume":"9","author":"Kleinhans","year":"2016","journal-title":"Autism Res. Off. J. Int. Soc. Autism Res."},{"key":"10.1016\/j.jad.2021.11.005_bib0037","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1023\/A:1025048802629","article-title":"The emotional brain, fear, and the amygdala","volume":"23","author":"LeDoux","year":"2003","journal-title":"Cell. Mol. Neurobiol."},{"key":"10.1016\/j.jad.2021.11.005_bib0038","doi-asserted-by":"crossref","first-page":"R868","DOI":"10.1016\/j.cub.2007.08.005","article-title":"The amygdala","volume":"17","author":"LeDoux","year":"2007","journal-title":"Curr. Biol. CB"},{"key":"10.1016\/j.jad.2021.11.005_bib0039","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1146\/annurev.neuro.23.1.155","article-title":"Emotion circuits in the brain","volume":"23","author":"LeDoux","year":"2000","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.jad.2021.11.005_bib0040","doi-asserted-by":"crossref","first-page":"8374","DOI":"10.1523\/JNEUROSCI.0486-17.2017","article-title":"Basolateral amygdala to orbitofrontal cortex projections enable cue-triggered reward expectations","volume":"37","author":"Lichtenberg","year":"2017","journal-title":"J. Neurosci. Off. J. Soc. Neurosci."},{"key":"10.1016\/j.jad.2021.11.005_bib0041","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1038\/nrn728","article-title":"Parallels between cerebellum- and amygdala-dependent conditioning","volume":"3","author":"Medina","year":"2002","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.jad.2021.11.005_bib0042","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.tics.2011.11.003","article-title":"Obsessive-compulsive disorder: beyond segregated cortico-striatal pathways","volume":"16","author":"Milad","year":"2012","journal-title":"Trends Cogn. Sci. (Regul. Ed.)"},{"key":"10.1016\/j.jad.2021.11.005_bib0043","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1002\/da.20484","article-title":"Duration effect of obsessive-compulsive disorder on cognitive function: a functional MRI study","volume":"26","author":"Nakao","year":"2009","journal-title":"Depress Anxiety"},{"key":"10.1016\/j.jad.2021.11.005_bib0044","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1001\/archpsyc.57.4.358","article-title":"A family study of obsessive-compulsive disorder","volume":"57","author":"Nestadt","year":"2000","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.jad.2021.11.005_bib0045","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.neuropsychologia.2011.02.030","article-title":"Reprint of: emotion and cognition and the amygdala: from \u201cwhat is it?\u201d to \"what\u2019s to be done?","volume":"49","author":"Pessoa","year":"2011","journal-title":"Neuropsychologia"},{"key":"10.1016\/j.jad.2021.11.005_bib0046","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.neuron.2005.09.025","article-title":"Contributions of the amygdala to emotion processing: from animal models to human behavior","volume":"48","author":"Phelps","year":"2005","journal-title":"Neuron"},{"key":"10.1016\/j.jad.2021.11.005_bib0047","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1002\/da.22845","article-title":"Intrinsic functional and structural connectivity of emotion regulation networks in obsessive-compulsive disorder","volume":"36","author":"Pico-Perez","year":"2019","journal-title":"Depress Anxiety"},{"key":"10.1016\/j.jad.2021.11.005_bib0048","doi-asserted-by":"crossref","first-page":"703","DOI":"10.4088\/JCP.v67n0503","article-title":"The brown longitudinal obsessive compulsive study: clinical features and symptoms of the sample at intake","volume":"67","author":"Pinto","year":"2006","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.jad.2021.11.005_bib0049","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1111\/j.1749-6632.2003.tb07070.x","article-title":"Comparative aspects of amygdala connectivity","volume":"985","author":"Price","year":"2003","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.jad.2021.11.005_bib0050","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1196\/annals.1401.008","article-title":"Definition of the orbital cortex in relation to specific connections with limbic and visceral structures and other cortical regions","volume":"1121","author":"Price","year":"2007","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.jad.2021.11.005_bib0051","doi-asserted-by":"crossref","first-page":"7941","DOI":"10.1073\/pnas.1120408109","article-title":"Immature integration and segregation of emotion-related brain circuitry in young children","volume":"109","author":"Qin","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.jad.2021.11.005_bib0052","doi-asserted-by":"crossref","first-page":"3380","DOI":"10.1523\/JNEUROSCI.4374-12.2013","article-title":"Differential effects of amygdala, orbital prefrontal cortex, and prelimbic cortex lesions on goal-directed behavior in rhesus macaques","volume":"33","author":"Rhodes","year":"2013","journal-title":"J. Neurosci. Off. J. Soc. Neurosci."},{"key":"10.1016\/j.jad.2021.11.005_bib0053","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.neuroscience.2018.05.051","article-title":"The limbic and sensorimotor pathways of the human amygdala: a structural connectivity study","volume":"385","author":"Rizzo","year":"2018","journal-title":"Neuroscience"},{"key":"10.1016\/j.jad.2021.11.005_bib0054","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.neuron.2019.01.046","article-title":"Obsessive-compulsive disorder: puzzles and prospects","volume":"102","author":"Robbins","year":"2019","journal-title":"Neuron"},{"key":"10.1016\/j.jad.2021.11.005_bib0055","doi-asserted-by":"crossref","first-page":"1899","DOI":"10.1176\/appi.ajp.158.11.1899","article-title":"Adults with early-onset obsessive-compulsive disorder","volume":"158","author":"Rosario-Campos","year":"2001","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.jad.2021.11.005_bib0056","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.jaac.2012.12.010","article-title":"Intrinsic functional connectivity of amygdala-based networks in adolescent generalized anxiety disorder","volume":"52","author":"Roy","year":"2013","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"key":"10.1016\/j.jad.2021.11.005_bib0057","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/j.neuroimage.2008.11.030","article-title":"Functional connectivity of the human amygdala using resting state fMRI","volume":"45","author":"Roy","year":"2009","journal-title":"Neuroimage"},{"key":"10.1016\/j.jad.2021.11.005_bib0058","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.ijpsycho.2014.02.007","article-title":"Obsessive-compulsive disorder: a \"sensory-motor\" problem?","volume":"92","author":"Russo","year":"2014","journal-title":"Int. J. Psychophysiol."},{"key":"10.1016\/j.jad.2021.11.005_bib0059","doi-asserted-by":"crossref","first-page":"2875","DOI":"10.1111\/j.1460-9568.2007.05508.x","article-title":"Reversible inactivation of amygdala and cerebellum but not perirhinal cortex impairs reactivated fear memories","volume":"25","author":"Sacchetti","year":"2007","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.jad.2021.11.005_bib0060","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1177\/1073858405276428","article-title":"The cerebellum: synaptic changes and fear conditioning","volume":"11","author":"Sacchetti","year":"2005","journal-title":"Neuroscientist"},{"key":"10.1016\/j.jad.2021.11.005_bib0061","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/S0896-6273(03)00474-4","article-title":"Encoding predicted outcome and acquired value in orbitofrontal cortex during cue sampling depends upon input from basolateral amygdala","volume":"39","author":"Schoenbaum","year":"2003","journal-title":"Neuron"},{"key":"10.1016\/j.jad.2021.11.005_bib0062","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1016\/S0306-4522(99)90280-4","article-title":"Afferent connections of the interstitial nucleus of the posterior limb of the anterior commissure and adjacent amygdalostriatal transition area in the rat","volume":"94","author":"Shammah-Lagnado","year":"1999","journal-title":"Neuroscience"},{"key":"10.1016\/j.jad.2021.11.005_bib0063","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1053\/comp.2000.9009","article-title":"Phenotypic differences in early- and late-onset obsessive-compulsive disorder","volume":"41","author":"Sobin","year":"2000","journal-title":"Compr. Psychiatry"},{"key":"10.1016\/j.jad.2021.11.005_bib0064","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1038\/s41572-019-0102-3","article-title":"Obsessive-compulsive disorder","volume":"5","author":"Stein","year":"2019","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.jad.2021.11.005_bib0065","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.cortex.2009.11.008","article-title":"Evidence for topographic organization in the cerebellum of motor control versus cognitive and affective processing","volume":"46","author":"Stoodley","year":"2010","journal-title":"Cortex"},{"key":"10.1016\/j.jad.2021.11.005_bib0066","doi-asserted-by":"crossref","first-page":"3799","DOI":"10.1073\/pnas.1814292116","article-title":"Basolateral amygdala input to the medial prefrontal cortex controls obsessive-compulsive disorder-like checking behavior","volume":"116","author":"Sun","year":"2019","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jad.2021.11.005_bib0067","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1002\/da.22901","article-title":"Anomalous functional connectivity of amygdala subregional networks in major depressive disorder","volume":"36","author":"Tang","year":"2019","journal-title":"Depress Anxiety"},{"key":"10.1016\/j.jad.2021.11.005_bib0068","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1016\/j.cpr.2011.06.007","article-title":"Early versus late onset obsessive-compulsive disorder: evidence for distinct subtypes","volume":"31","author":"Taylor","year":"2011","journal-title":"Clin. Psychol. Rev."},{"key":"10.1016\/j.jad.2021.11.005_bib0069","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.neuroimage.2013.12.058","article-title":"Cluster-extent based thresholding in fMRI analyses: pitfalls and recommendations","volume":"91","author":"Woo","year":"2014","journal-title":"Neuroimage"},{"key":"10.1016\/j.jad.2021.11.005_bib0070","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.neuroimage.2013.03.004","article-title":"A comprehensive assessment of regional variation in the impact of head micromovements on functional connectomics","volume":"76","author":"Yan","year":"2013","journal-title":"Neuroimage"},{"key":"10.1016\/j.jad.2021.11.005_bib0071","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1007\/s12021-016-9299-4","article-title":"DPABI: data processing & analysis for (resting-state) brain imaging","volume":"14","author":"Yan","year":"2016","journal-title":"Neuroinformatics"},{"key":"10.1016\/j.jad.2021.11.005_bib0072","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/j.0956-7976.2005.00792.x","article-title":"Who sees trees before forest? The obsessive-compulsive style of visual attention","volume":"16","author":"Yovel","year":"2005","journal-title":"Psychol. Sci."},{"key":"10.1016\/j.jad.2021.11.005_bib0073","doi-asserted-by":"crossref","first-page":"3548","DOI":"10.1016\/j.neuroimage.2011.11.023","article-title":"Functional connectivity mapping of the human precuneus by resting state fMRI","volume":"59","author":"Zhang","year":"2012","journal-title":"Neuroimage"},{"key":"10.1016\/j.jad.2021.11.005_bib0074","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1038\/nrn2776","article-title":"Centenary of Brodmann\u2019s map-conception and fate","volume":"11","author":"Zilles","year":"2010","journal-title":"Nat. Rev. Neurosci."}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032721012234?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032721012234?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T02:29:11Z","timestamp":1759026551000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165032721012234"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":74,"alternative-id":["S0165032721012234"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2021.11.005","relation":{},"ISSN":["0165-0327"],"issn-type":[{"value":"0165-0327","type":"print"}],"subject":[],"published":{"date-parts":[[2022,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Distinct alterations of amygdala subregional functional connectivity in early- and late-onset obsessive-compulsive disorder","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2021.11.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}