{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T15:11:22Z","timestamp":1778425882597,"version":"3.51.4"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2023,3]]},"DOI":"10.1016\/j.jad.2022.12.072","type":"journal-article","created":{"date-parts":[[2022,12,29]],"date-time":"2022-12-29T19:57:50Z","timestamp":1672343870000},"page":"410-417","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Cardiovascular risk in bipolar disorder \u2013 A case for the hypothalamus-pituitary-adrenal axis?"],"prefix":"10.1016","volume":"324","author":[{"given":"Felicitas","family":"Knedeisen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Britta","family":"Stapel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivo","family":"Heitland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ralf","family":"Lichtinghagen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrich","family":"Schweiger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dagmar","family":"Hartung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai G.","family":"Kahl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jad.2022.12.072_bb0005","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1161\/CIRCULATIONAHA.114.015000","article-title":"Association between visceral and subcutaneous adipose depots and incident cardiovascular disease risk factors","volume":"132","author":"Abraham","year":"2015","journal-title":"Circulation"},{"key":"10.1016\/j.jad.2022.12.072_bb0010","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0165-0327(01)00377-9","article-title":"Mortality of patients with mood disorders: follow-up over 34\u201338 years","volume":"68","author":"Angst","year":"2002","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2022.12.072_bb0015","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1161\/hc0302.102575","article-title":"Simple scoring scheme for calculating the risk of acute coronary events based on the 10-year follow-up of the prospective cardiovascular Munster (PROCAM) study","volume":"105","author":"Assmann","year":"2002","journal-title":"Circulation"},{"issue":"82","key":"10.1016\/j.jad.2022.12.072_bb0020","first-page":"10","article-title":"Manual for the beck depression inventory-II","volume":"1","author":"Beck","year":"1996","journal-title":"San Antonio, TX: Psychological Corporation"},{"key":"10.1016\/j.jad.2022.12.072_bb0025","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.psyneuen.2015.10.014","article-title":"The HPA axis in bipolar disorder: systematic review and meta-analysis","volume":"63","author":"Belvederi Murri","year":"2016","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.jad.2022.12.072_bb0030","doi-asserted-by":"crossref","first-page":"1002143","DOI":"10.3389\/fpsyt.2022.1002143","article-title":"Behavioral pathway to a broken heart: the link between adverse childhood experiences, depression, physical exercise and cardiovascular health","volume":"13","author":"Bertele","year":"2022","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.jad.2022.12.072_bb0035","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1210\/er.2017-00253","article-title":"The science of obesity management: an endocrine society scientific statement","volume":"39","author":"Bray","year":"2018","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.jad.2022.12.072_bb0040","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/1741-7015-9-47","article-title":"Should global burden of disease estimates include depression as a risk factor for coronary heart disease?","volume":"9","author":"Charlson","year":"2011","journal-title":"BMC Med."},{"key":"10.1016\/j.jad.2022.12.072_bb0045","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1161\/CIRCULATIONAHA.119.042287","article-title":"Aerobic exercise induces cardiac fat loss and alters cardiac muscle mass through an Interleukin-6 receptor-dependent mechanism: cardiac analysis of a double-blind randomized controlled clinical trial in abdominally obese humans","volume":"140","author":"Christensen","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.jad.2022.12.072_bb0050","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1002\/wps.20204","article-title":"Effects of antipsychotics, antidepressants and mood stabilizers on risk for physical diseases in people with schizophrenia, depression and bipolar disorder","volume":"14","author":"Correll","year":"2015","journal-title":"World Psychiatry"},{"key":"10.1016\/j.jad.2022.12.072_bb0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1017\/S0033291709005558","article-title":"Not fade away: the HPA axis and depression","volume":"40","author":"Cowen","year":"2010","journal-title":"Psychol. Med."},{"key":"10.1016\/j.jad.2022.12.072_bb0060","first-page":"281","article-title":"A survey of physical activity levels of certified athletic trainers","volume":"37","author":"Cuppett","year":"2002","journal-title":"J. Athl. Train."},{"key":"10.1016\/j.jad.2022.12.072_bb0065","doi-asserted-by":"crossref","first-page":"2486","DOI":"10.1001\/jama.285.19.2486","article-title":"Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III)","volume":"285","year":"2001","journal-title":"JAMA"},{"key":"10.1016\/j.jad.2022.12.072_bb0070","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1097\/PSY.0b013e3181acee26","article-title":"Manic\/hypomanic symptom burden and cardiovascular mortality in bipolar disorder","volume":"71","author":"Fiedorowicz","year":"2009","journal-title":"Psychosom. Med."},{"key":"10.1016\/j.jad.2022.12.072_bb0075","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4158\/EP161365.GL","article-title":"American association of clinical endocrinologists and american college of endocrinology comprehensive clinical practice guidelines formedical care of patients with obesity","volume":"22","author":"Garvey","year":"2016","journal-title":"Endocr. Pract."},{"key":"10.1016\/j.jad.2022.12.072_bb0080","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1210\/jc.2006-2674","article-title":"Adrenal gland volume and dexamethasone-suppressed cortisol correlate with total daily salivary cortisol in African-American women","volume":"92","author":"Golden","year":"2007","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.jad.2022.12.072_bb0085","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1007\/s10654-011-9585-2","article-title":"Reliability of hypothalamic-pituitary-adrenal axis assessment methods for use in population-based studies","volume":"26","author":"Golden","year":"2011","journal-title":"Eur. J. Epidemiol."},{"key":"10.1016\/j.jad.2022.12.072_bb0090","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.psyneuen.2008.03.008","article-title":"The link between childhood trauma and depression: insights from HPA axis studies in humans","volume":"33","author":"Heim","year":"2008","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.jad.2022.12.072_bb0095","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/0012-1606(78)90263-4","article-title":"Formation of the epicardium studied with the scanning electron microscope","volume":"66","author":"Ho","year":"1978","journal-title":"Dev. Biol."},{"key":"10.1016\/j.jad.2022.12.072_bb0100","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1038\/nrendo.2015.58","article-title":"Local and systemic effects of the multifaceted epicardial adipose tissue depot","volume":"11","author":"Iacobellis","year":"2015","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.jad.2022.12.072_bb0105","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1016\/j.echo.2009.10.013","article-title":"Echocardiographic epicardial fat: a review of research and clinical applications","volume":"22","author":"Iacobellis","year":"2009","journal-title":"J. Am. Soc. Echocardiogr."},{"key":"10.1016\/j.jad.2022.12.072_bb0110","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/acps.12242","article-title":"Pericardial, intra-abdominal, and subcutaneous adipose tissue in patients with major depressive disorder","volume":"130","author":"Kahl","year":"2014","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.jad.2022.12.072_bb0115","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.psyneuen.2015.04.008","article-title":"Adrenal gland volume, intra-abdominal and pericardial adipose tissue in major depressive disorder","volume":"58","author":"Kahl","year":"2015","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.jad.2022.12.072_bb0120","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.jad.2015.12.015","article-title":"Effects of additional exercise training on epicardial, intra-abdominal and subcutaneous adipose tissue in major depressive disorder: a randomized pilot study","volume":"192","author":"Kahl","year":"2016","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2022.12.072_bb0125","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.pnpbp.2016.08.005","article-title":"Pericardial adipose tissue and the metabolic syndrome is increased in patients with chronic major depressive disorder compared to acute depression and controls","volume":"72","author":"Kahl","year":"2017","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.jad.2022.12.072_bb0130","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.pnpbp.2017.01.009","article-title":"Reduced muscle mass in middle-aged depressed patients is associated with male gender and chronicity","volume":"76","author":"Kahl","year":"2017","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.jad.2022.12.072_bb0135","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.4088\/JCP.v64n1205","article-title":"Bipolar disorder, obesity, and pharmacotherapy-associated weight gain","volume":"64","author":"Keck","year":"2003","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.jad.2022.12.072_bb0140","doi-asserted-by":"crossref","first-page":"725","DOI":"10.2337\/diacare.26.3.725","article-title":"The diabetes risk score: a practical tool to predict type 2 diabetes risk","volume":"26","author":"Lindstrom","year":"2003","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jad.2022.12.072_bb0145","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/0305-0491(89)90337-4","article-title":"Adipose tissue in the mammalian heart and pericardium: structure, foetal development and biochemical properties","volume":"94","author":"Marchington","year":"1989","journal-title":"Comparative biochemistry and physiologyB, Comparative biochemistry"},{"key":"10.1016\/j.jad.2022.12.072_bb0150","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1016\/0026-0495(92)90016-4","article-title":"The morphology and metabolism of intraabdominal adipose tissue in men","volume":"41","author":"M\u00e5rin","year":"1992","journal-title":"Metabolism"},{"key":"10.1016\/j.jad.2022.12.072_bb0155","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.schres.2014.07.022","article-title":"Standard cardiovascular disease risk algorithms underestimate the risk of cardiovascular disease in schizophrenia: evidence from a national primary care database","volume":"159","author":"McLean","year":"2014","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.jad.2022.12.072_bb0160","doi-asserted-by":"crossref","first-page":"101","DOI":"10.3389\/fpsyt.2019.00101","article-title":"Is the HPA Axis as target for depression outdated, or is there a new hope?","volume":"10","author":"Menke","year":"2019","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.jad.2022.12.072_bb0165","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1160\/TH13-04-0285","article-title":"Ectopic fat: the true culprit linking obesity and cardiovascular disease?","volume":"110","author":"Morelli","year":"2013","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.jad.2022.12.072_bb0170","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.genhosppsych.2017.04.003","article-title":"Lifestyle interventions for weight loss among overweight and obese adults with serious mental illness: a systematic review and meta-analysis","volume":"47","author":"Naslund","year":"2017","journal-title":"Gen. Hosp. Psychiatry"},{"key":"10.1016\/j.jad.2022.12.072_bb0175","doi-asserted-by":"crossref","first-page":"2763","DOI":"10.1093\/eurheartj\/ehl338","article-title":"Depression as an aetiologic and prognostic factor in coronary heart disease: a meta-analysis of 6362 events among 146 538 participants in 54 observational studies","volume":"27","author":"Nicholson","year":"2006","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.jad.2022.12.072_bb0180","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1038\/s41569-020-00463-7","article-title":"Cardiovascular disease in patients with severe mental illness","volume":"18","author":"Nielsen","year":"2021","journal-title":"Nat. Rev. Cardiol."},{"key":"10.1016\/j.jad.2022.12.072_bb0185","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1001\/archpsyc.58.9.844","article-title":"Excess mortality in bipolar and unipolar disorder in Sweden","volume":"58","author":"Osby","year":"2001","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.jad.2022.12.072_bb0190","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1002\/oby.23125","article-title":"Deciphering the association between hypothalamus-pituitary-adrenal Axis activity and obesity: a meta-analysis","volume":"29","author":"Ostinelli","year":"2021","journal-title":"Obesity (Silver Spring)"},{"key":"10.1016\/j.jad.2022.12.072_bb0195","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1176\/appi.ajp.163.2.225","article-title":"Clinical features of bipolar depression versus major depressive disorder in large multicenter trials","volume":"163","author":"Perlis","year":"2006","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.jad.2022.12.072_bb0200","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.jad.2012.11.020","article-title":"Role of childhood adversity in the development of medical co-morbidities associated with bipolar disorder","volume":"147","author":"Post","year":"2013","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2022.12.072_bb0205","doi-asserted-by":"crossref","first-page":"e984","DOI":"10.1161\/CIR.0000000000000973","article-title":"Obesity and cardiovascular disease: a scientific statement from the American Heart Association","volume":"143","author":"Powell-Wiley","year":"2021","journal-title":"Circulation"},{"key":"10.1016\/j.jad.2022.12.072_bb0210","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.jpsychires.2021.10.039","article-title":"Epicardial adipose tissue and adrenal gland volume in patients with borderline personality disorder","volume":"144","author":"Richter","year":"2021","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.jad.2022.12.072_bb0215","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/j.jacc.2004.12.005","article-title":"The epidemiology, pathophysiology, and management of psychosocial risk factors in cardiac practice: the emerging field of behavioral cardiology","volume":"45","author":"Rozanski","year":"2005","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.jad.2022.12.072_bb0220","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.ahj.2007.03.019","article-title":"Human epicardial adipose tissue: a review","volume":"153","author":"Sacks","year":"2007","journal-title":"Am. Heart J."},{"key":"10.1016\/j.jad.2022.12.072_bb0225","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1007\/s10654-010-9483-z","article-title":"Leisure-time physical activity, cardiovascular risk factors and mortality during a 34-year follow-up in men","volume":"25","author":"Savela","year":"2010","journal-title":"Eur. J. Epidemiol."},{"key":"10.1016\/j.jad.2022.12.072_bb0230","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.jad.2007.03.002","article-title":"Exercise tolerance is reduced in bipolar illness","volume":"104","author":"Shah","year":"2007","journal-title":"J. Affect. Disord."},{"issue":"12","key":"10.1016\/j.jad.2022.12.072_bb0235","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1016\/j.jcmg.2014.07.017","article-title":"Visceral adiposity and the risk of metabolic syndrome across body mass index: the MESA study","volume":"7","author":"Shah","year":"2014","journal-title":"JACC Cardiovasc. Imaging"},{"key":"10.1016\/j.jad.2022.12.072_bb0240","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1016\/j.jcmg.2016.10.024","article-title":"Pericardial, but not hepatic, fat by CT is associated with CV outcomes and structure: the multi-ethnic study of atherosclerosis","volume":"10","author":"Shah","year":"2017","journal-title":"JACC Cardiovasc. Imaging"},{"key":"10.1016\/j.jad.2022.12.072_bb0245","first-page":"26","article-title":"Echocardiographic assessment of epicardial adipose tissue\u2013a marker of visceral adiposity","volume":"10","author":"Singh","year":"2007","journal-title":"Mcgill J. Med."},{"key":"10.1016\/j.jad.2022.12.072_bb0250","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.jad.2012.01.005","article-title":"Mood disorder symptoms and elevated cardiovascular disease risk in patients with bipolar disorder","volume":"138","author":"Slomka","year":"2012","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2022.12.072_bb0255","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2022.831358","article-title":"Adipose tissue compartments, inflammation, and cardiovascular risk in the context of depression","volume":"13","author":"Stapel","year":"2022","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.jad.2022.12.072_bb0260","first-page":"416","article-title":"Epicardial adipose tissue: far more than a fat depot","volume":"4","author":"Talman","year":"2014","journal-title":"Cardiovasc. Diagn. Ther."},{"key":"10.1016\/j.jad.2022.12.072_bb0265","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2016-013831","article-title":"Risk for metabolic diseases in normal weight individuals with visceral fat accumulation: a cross-sectional study in Japan","volume":"7","author":"Tatsumi","year":"2017","journal-title":"BMJ Open"},{"key":"10.1016\/j.jad.2022.12.072_bb0270","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/S0140-6736(06)69249-0","article-title":"Tobacco use and risk of myocardial infarction in 52 countries in the INTERHEART study: a case-control study","volume":"368","author":"Teo","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.jad.2022.12.072_bb0275","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1177\/104012371102300107","article-title":"Cardiovascular morbidity and mortality in bipolar disorder","volume":"23","author":"Weiner","year":"2011","journal-title":"Ann. Clin. Psychiatry"},{"key":"10.1016\/j.jad.2022.12.072_bb0280","doi-asserted-by":"crossref","first-page":"904","DOI":"10.4088\/JCP.v67n0607","article-title":"Obesity in patients with bipolar disorder: a biopsychosocial-behavioral model","volume":"67","author":"Wildes","year":"2006","journal-title":"J Clin Psychiatry"}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016503272201432X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016503272201432X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T03:53:30Z","timestamp":1759031610000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016503272201432X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3]]},"references-count":56,"alternative-id":["S016503272201432X"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2022.12.072","relation":{},"ISSN":["0165-0327"],"issn-type":[{"value":"0165-0327","type":"print"}],"subject":[],"published":{"date-parts":[[2023,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cardiovascular risk in bipolar disorder \u2013 A case for the hypothalamus-pituitary-adrenal axis?","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2022.12.072","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}