{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T03:19:04Z","timestamp":1792034344159,"version":"4.4.0"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1016\/j.jad.2023.02.047","type":"journal-article","created":{"date-parts":[[2023,2,27]],"date-time":"2023-02-27T01:59:56Z","timestamp":1677463196000},"page":"1-6","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["BrainAge of patients with severe late-life depression referred for electroconvulsive therapy"],"prefix":"10.1016","volume":"330","author":[{"given":"Margot J.","family":"Wagenmakers","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mardien L.","family":"Oudega","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Klaus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Wing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gwendolyn","family":"Orav","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura K.M.","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Binnewies","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aartjan T.F.","family":"Beekman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dick J.","family":"Veltman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didi","family":"Rhebergen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"van Exel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa T.","family":"Eyler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annemieke","family":"Dols","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jad.2023.02.047_bb0005","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1016\/j.jagp.2021.11.011","article-title":"Structural MRI-based measures of accelerated brain aging do not moderate the acute antidepressant response in late-life depression","volume":"30","author":"Ahmed","year":"2022","journal-title":"Am. J. Geriatr. Psychiatry"},{"key":"10.1016\/j.jad.2023.02.047_bb0010","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.1016\/S0140-6736(05)66665-2","article-title":"Depression in the elderly","volume":"365","author":"Alexopoulos","year":"2005","journal-title":"Lancet (London, England)"},{"key":"10.1016\/j.jad.2023.02.047_bb0015","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1111\/acps.13371","article-title":"Brain age in mood and psychotic disorders: a systematic review and meta-analysis","volume":"145","author":"Ballester","year":"2021","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.jad.2023.02.047_bb0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.pscychresns.2019.06.001","article-title":"Machine-learning based brain age estimation in major depression showing no evidence of accelerated aging","volume":"290","author":"Besteher","year":"2019","journal-title":"Psychiatry Res. Neuroimaging"},{"key":"10.1016\/j.jad.2023.02.047_bb0025","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1038\/s41398-020-01004-z","article-title":"Accelerated brain aging predicts impaired cognitive performance and greater disability in geriatric but not midlife adult depression","volume":"10","author":"Christman","year":"2020","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.jad.2023.02.047_bb0030","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.tins.2017.10.001","article-title":"Predicting age using neuroimaging: innovative brain ageing biomarkers","volume":"40","author":"Cole","year":"2017","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.jad.2023.02.047_bb0035","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.neuroimage.2017.07.059","article-title":"Predicting brain age with deep learning from raw imaging data results in a reliable and heritable biomarker","volume":"163","author":"Cole","year":"2017","journal-title":"NeuroImage"},{"key":"10.1016\/j.jad.2023.02.047_bb0040","series-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"Association","year":"2000"},{"key":"10.1016\/j.jad.2023.02.047_bb0045","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1192\/bjp.2018.67","article-title":"Prediction of electroconvulsive therapy response and remission in major depression: meta-analysis - CORRIGENDUM","volume":"212","author":"van Diermen","year":"2018","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.jad.2023.02.047_bb0050","first-page":"80","article-title":"Psychotic features in patients with major depressive disorder: a report from the European Group for the Study of Resistant Depression","author":"Dold","year":"2019","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.jad.2023.02.047_bb0055","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.jagp.2016.09.005","article-title":"Early- and late-onset depression in late life: a prospective study on clinical and structural brain characteristics and response to electroconvulsive therapy","volume":"25","author":"Dols","year":"2017","journal-title":"Am. J. Geriatr. Psychiatry"},{"key":"10.1016\/j.jad.2023.02.047_bb0060","doi-asserted-by":"crossref","first-page":"789","DOI":"10.3389\/fneur.2019.00789","article-title":"Ten years of BrainAGE as a neuroimaging biomarker of brain aging: what insights have we gained?","volume":"10","author":"Franke","year":"2019","journal-title":"Front. Neurol."},{"key":"10.1016\/j.jad.2023.02.047_bb0065","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.comppsych.2008.02.007","article-title":"Depressive symptom profiles and severity patterns in outpatients with psychotic vs nonpsychotic major depression","volume":"49","author":"Gaudiano","year":"2008","journal-title":"Compr. Psychiatry"},{"key":"10.1016\/j.jad.2023.02.047_bb0070","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.biopsych.2005.11.010","article-title":"The neuropsychological profile of psychotic major depression and its relation to cortisol","volume":"60","author":"Gomez","year":"2006","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2023.02.047_bb0075","doi-asserted-by":"crossref","first-page":"5124","DOI":"10.1038\/s41380-020-0754-0","article-title":"Brain aging in major depressive disorder: results from the ENIGMA major depressive disorder working group","volume":"26","author":"Han","year":"2021","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jad.2023.02.047_bb0080","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1038\/s41593-019-0471-7","article-title":"Common brain disorders are associated with heritable patterns of apparent aging of the brain","volume":"22","author":"Kaufmann","year":"2019","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.jad.2023.02.047_bb0085","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1111\/acel.12601","article-title":"Molecular and physiological manifestations and measurement of aging in humans","volume":"16","author":"Khan","year":"2017","journal-title":"Aging Cell"},{"key":"10.1016\/j.jad.2023.02.047_bb0090","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1093\/schbul\/sbt142","article-title":"Accelerated brain aging in schizophrenia and beyond: a neuroanatomical marker of psychiatric disorders","volume":"40","author":"Koutsouleris","year":"2014","journal-title":"Schizophr. Bull."},{"key":"10.1016\/j.jad.2023.02.047_bb0095","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1093\/arclin\/acw069","article-title":"Treatment-resistant major depressive disorder with psychotic features is associated with impaired processing speed","volume":"31","author":"Leinola","year":"2016","journal-title":"Arch. Clin. Neuropsychol."},{"key":"10.1016\/j.jad.2023.02.047_bb0100","doi-asserted-by":"crossref","first-page":"274","DOI":"10.21037\/atm.2020.02.63","article-title":"Clinical prediction models in the precision medicine era: old and new algorithms","volume":"8","author":"Luo","year":"2020","journal-title":"Ann. Transl. Med."},{"key":"10.1016\/j.jad.2023.02.047_bb0105","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1192\/bjp.134.4.382","article-title":"A new depression scale designed to be sensitive to change","volume":"134","author":"Montgomery","year":"1979","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.jad.2023.02.047_bb0110","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1038\/s41380-019-0392-6","article-title":"Volume increase in the dentate gyrus after electroconvulsive therapy in depressed patients as measured with 7T","volume":"25","author":"Nuninga","year":"2020","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jad.2023.02.047_bb0115","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1016\/j.biopsych.2018.05.017","article-title":"Volume of the human hippocampus and clinical response following electroconvulsive therapy","volume":"84","author":"Oltedal","year":"2018","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2023.02.047_bb0120","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.pscychresns.2014.03.002","article-title":"The structure of the geriatric depressed brain and response to electroconvulsive therapy","volume":"222","author":"Oudega","year":"2014","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.jad.2023.02.047_bb0125","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1038\/mp.2015.69","article-title":"Subcortical brain alterations in major depressive disorder: findings from the ENIGMA major depressive disorder working group","volume":"21","author":"Schmaal","year":"2016","journal-title":"Mol. Psychiatry"},{"issue":"Suppl. 20","key":"10.1016\/j.jad.2023.02.047_bb0130","first-page":"22","article-title":"The mini-international neuropsychiatric interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10","volume":"59","author":"Sheehan","year":"1998","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.jad.2023.02.047_bb0135","first-page":"12","article-title":"Neuroimaging-derived brain age is associated with life satisfaction in cognitively unimpaired elderly: a community-based study","author":"Sone","year":"2022","journal-title":"Transcult. Psychiatry"},{"key":"10.1016\/j.jad.2023.02.047_bb0140","article-title":"Richtlijn elektroconvulsietherapie","volume":"36","author":"Van den Broek","year":"2010","journal-title":"Ned Ver Voor Psychiatr."},{"key":"10.1016\/j.jad.2023.02.047_bb0145","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1186\/s12883-021-02331-4","article-title":"Factors associated with brain ageing - a systematic review","volume":"21","author":"Wrigglesworth","year":"2021","journal-title":"BMC Neurol."}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032723002100?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032723002100?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T03:42:11Z","timestamp":1759030931000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165032723002100"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":29,"alternative-id":["S0165032723002100"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2023.02.047","relation":{},"ISSN":["0165-0327"],"issn-type":[{"value":"0165-0327","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"BrainAge of patients with severe late-life depression referred for electroconvulsive therapy","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2023.02.047","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}