{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T11:41:04Z","timestamp":1784806864910,"version":"3.55.0"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.jad.2023.05.024","type":"journal-article","created":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T02:21:09Z","timestamp":1683771669000},"page":"105-110","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Right dorsolateral prefrontal cortex volumetric reduction is associated with antidepressant effect of low-dose ketamine infusion: A randomized, double-blind, midazolam-controlled PET-MRI clinical trial"],"prefix":"10.1016","volume":"335","author":[{"given":"Wei-Chi","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Fen","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tung-Ping","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng-Ta","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Chen","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui-Ju","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih-Jen","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya-Mei","family":"Bai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei-Chi","family":"Tu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mu-Hong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jad.2023.05.024_bb0005","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1038\/npp.2016.186","article-title":"Ketamine treatment and global brain connectivity in major depression","volume":"42","author":"Abdallah","year":"2017","journal-title":"Neuropsychopharmacol."},{"key":"10.1016\/j.jad.2023.05.024_bb0010","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.jpsychires.2022.04.037","article-title":"Real-world effectiveness of ketamine in treatment-resistant depression: a systematic review & meta-analysis","volume":"151","author":"Alnefeesi","year":"2022","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.jad.2023.05.024_bb0020","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1093\/ijnp\/pyac055","article-title":"A participant-level integrative data analysis of differential placebo response for suicidal ideation and nonsuicidal depressive symptoms in clinical trials of intravenous racemic ketamine","volume":"25","author":"Bloomfield-Clagett","year":"2022","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.jad.2023.05.024_bb0025","doi-asserted-by":"crossref","first-page":"2223","DOI":"10.1001\/jama.2018.6360","article-title":"Randomization in clinical trials: permuted blocks and stratification","volume":"319","author":"Broglio","year":"2018","journal-title":"Jama."},{"key":"10.1016\/j.jad.2023.05.024_bb0030","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/j.jad.2017.09.008","article-title":"Persistent antidepressant effect of low-dose ketamine and activation in the supplementary motor area and anterior cingulate cortex in treatment-resistant depression: a randomized control study","volume":"225","author":"Chen","year":"2018","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2023.05.024_bb0035","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.jad.2019.08.022","article-title":"Antidepressant and antisuicidal effects of ketamine on the functional connectivity of prefrontal cortex-related circuits in treatment-resistant depression: a double-blind, placebo-controlled, randomized, longitudinal resting fMRI study","volume":"259","author":"Chen","year":"2019","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2023.05.024_bb0040","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1007\/s00406-021-01264-w","article-title":"Effects of treatment refractoriness and brain-derived neurotrophic factor Val66Met polymorphism on antidepressant response to low-dose ketamine infusion","volume":"271","author":"Chen","year":"2021","journal-title":"Eur. Arch. Psychiatry Clin. Neurosci."},{"key":"10.1016\/j.jad.2023.05.024_bb0045","doi-asserted-by":"crossref","DOI":"10.1177\/2470547020980681","article-title":"Ketamine normalizes the structural alterations of inferior frontal gyrus in depression","volume":"4","author":"Dai","year":"2020","journal-title":"Chronic Stress."},{"key":"10.1016\/j.jad.2023.05.024_bb0050","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1038\/s41380-018-0256-5","article-title":"Double-blind, placebo-controlled, dose-ranging trial of intravenous ketamine as adjunctive therapy in treatment-resistant depression (TRD)","volume":"25","author":"Fava","year":"2020","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jad.2023.05.024_bb0055","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1002\/da.20454","article-title":"A randomized trial of the anti-depressant effects of low- and high-frequency transcranial magnetic stimulation in treatment-resistant depression","volume":"26","author":"Fitzgerald","year":"2009","journal-title":"Depress. Anxiety"},{"key":"10.1016\/j.jad.2023.05.024_bb0060","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1002\/da.22968","article-title":"Defining treatment-resistant depression","volume":"37","author":"Gaynes","year":"2020","journal-title":"Depress. Anxiety"},{"key":"10.1016\/j.jad.2023.05.024_bb0065","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1176\/appi.ajp.2017.17060647","article-title":"Ketamine for rapid reduction of suicidal thoughts in major depression: a midazolam-controlled randomized clinical trial","volume":"175","author":"Grunebaum","year":"2018","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.jad.2023.05.024_bb0070","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.euroneuro.2020.11.017","article-title":"Gray matter volume of rostral anterior cingulate cortex predicts rapid antidepressant response to ketamine","volume":"43","author":"Herrera-Melendez","year":"2021","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.jad.2023.05.024_bb0075","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.neuroimage.2016.12.032","article-title":"Imaging the neuroplastic effects of ketamine with VBM and the necessity of placebo control","volume":"147","author":"Hoflich","year":"2017","journal-title":"NeuroImage."},{"key":"10.1016\/j.jad.2023.05.024_bb0080","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1111\/j.1526-4610.2000.00148.x","article-title":"Comorbidity of depressive and anxiety disorders in chronic daily headache and its subtypes","volume":"40","author":"Juang","year":"2000","journal-title":"Headache."},{"key":"10.1016\/j.jad.2023.05.024_bb0085","doi-asserted-by":"crossref","first-page":"12341","DOI":"10.1523\/JNEUROSCI.2324-08.2008","article-title":"Distinct regions of prefrontal cortex mediate resistance and vulnerability to depression","volume":"28","author":"Koenigs","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jad.2023.05.024_bb0090","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.neuroimage.2009.11.021","article-title":"Structural and cognitive deficits in remitting and non-remitting recurrent depression: a voxel-based morphometric study","volume":"50","author":"Li","year":"2010","journal-title":"NeuroImage."},{"key":"10.1016\/j.jad.2023.05.024_bb0095","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1192\/bjp.bp.113.140434","article-title":"Prefrontal glucose metabolism in medication-resistant major depression","volume":"206","author":"Li","year":"2015","journal-title":"Brit. J. Psychiat."},{"key":"10.1016\/j.jad.2023.05.024_bb0100","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1002\/hbm.23085","article-title":"The effects of low-dose ketamine on the prefrontal cortex and amygdala in treatment-resistant depression: a randomized controlled study","volume":"37","author":"Li","year":"2016","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.jad.2023.05.024_bb0105","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/s12264-016-0025-x","article-title":"Structural asymmetry of dorsolateral prefrontal cortex correlates with depressive symptoms: evidence from healthy individuals and patients with major depressive disorder","volume":"32","author":"Liu","year":"2016","journal-title":"Neurosci. Bull."},{"key":"10.1016\/j.jad.2023.05.024_bb0110","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1192\/bjp.177.2.169","article-title":"Interhemispheric asymmetry of motor cortical excitability in major depression as measured by transcranial magnetic stimulation","volume":"177","author":"Maeda","year":"2000","journal-title":"Brit. J. Psychiat."},{"key":"10.1016\/j.jad.2023.05.024_bb0115","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1016\/0028-3908(80)90199-9","article-title":"Maprotiline, nomifensine, mianserin, zimelidine: a review of antidepressant efficacy in in-patients","volume":"19","author":"Montgomery","year":"1980","journal-title":"Neuropharmacology."},{"key":"10.1016\/j.jad.2023.05.024_bb0120","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1176\/appi.ajp.2013.13030392","article-title":"Antidepressant efficacy of ketamine in treatment-resistant major depression: a two-site randomized controlled trial","volume":"170","author":"Murrough","year":"2013","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.jad.2023.05.024_bb0125","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1176\/appi.ajp.2011.10111704","article-title":"The Columbia-Suicide Severity Rating Scale: initial validity and internal consistency findings from three multisite studies with adolescents and adults","volume":"168","author":"Posner","year":"2011","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.jad.2023.05.024_bb0130","series-title":"Experimental Design and Analysis","first-page":"319","article-title":"Contrasts and custom hypotheses. In","author":"Seltman","year":"2018"},{"key":"10.1016\/j.jad.2023.05.024_bb0135","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.neuroimage.2008.03.061","article-title":"Threshold-free cluster enhancement: addressing problems of smoothing, threshold dependence and localisation in cluster inference","volume":"44","author":"Smith","year":"2009","journal-title":"NeuroImage."},{"key":"10.1016\/j.jad.2023.05.024_bb0140","doi-asserted-by":"crossref","first-page":"2482","DOI":"10.1038\/npp.2017.94","article-title":"Dose-related effects of adjunctive ketamine in Taiwanese patients with treatment-resistant depression","volume":"42","author":"Su","year":"2017","journal-title":"Neuropsychopharmacol."},{"key":"10.1016\/j.jad.2023.05.024_bb0145","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.jad.2021.02.043","article-title":"Evaluation of MADRS severity thresholds in patients with bipolar depression","volume":"286","author":"Thase","year":"2021","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2023.05.024_bb0150","doi-asserted-by":"crossref","first-page":"E186","DOI":"10.1503\/jpn.210131","article-title":"Frontal asymmetry as a core feature of major depression: a functional near-infrared spectroscopy study","volume":"47","author":"Tseng","year":"2022","journal-title":"J. Psychiat. Neurosci."},{"key":"10.1016\/j.jad.2023.05.024_bb0155","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1002\/da.22498","article-title":"Ketamine: a potential rapid-acting antisuicidal agent?","volume":"33","author":"Wilkinson","year":"2016","journal-title":"Depress. Anxiety"},{"key":"10.1016\/j.jad.2023.05.024_bb0160","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1038\/mp.2016.72","article-title":"Common and distinct patterns of grey-matter volume alteration in major depression and bipolar disorder: evidence from voxel-based meta-analysis","volume":"22","author":"Wise","year":"2017","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jad.2023.05.024_bb0165","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.jpsychires.2020.12.038","article-title":"The acute antisuicidal effects of single-dose intravenous ketamine and intranasal esketamine in individuals with major depression and bipolar disorders: a systematic review and meta-analysis","volume":"134","author":"Xiong","year":"2021","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.jad.2023.05.024_bb0170","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.jad.2013.04.028","article-title":"Severity classification on the Hamilton Depression Rating Scale","volume":"150","author":"Zimmerman","year":"2013","journal-title":"J. Affect. Disord."}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032723006511?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032723006511?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T04:03:42Z","timestamp":1759032222000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165032723006511"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":33,"alternative-id":["S0165032723006511"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2023.05.024","relation":{},"ISSN":["0165-0327"],"issn-type":[{"value":"0165-0327","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Right dorsolateral prefrontal cortex volumetric reduction is associated with antidepressant effect of low-dose ketamine infusion: A randomized, double-blind, midazolam-controlled PET-MRI clinical trial","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2023.05.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}