{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T02:04:24Z","timestamp":1773108264411,"version":"3.50.1"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1016\/j.jad.2023.10.006","type":"journal-article","created":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T04:59:25Z","timestamp":1696481965000},"page":"1-7","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Trait anxiety mediates the association between hippocampal\u2013insula functional connectivity and anxiety symptom severity in adults with and without generalized anxiety disorder"],"prefix":"10.1016","volume":"344","author":[{"given":"Shiyu","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingxiao","family":"Cao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hailong","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Du","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongqi","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingxu","family":"Duan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaoju","family":"Deng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoqi","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changjian","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiyong","family":"Gong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.jad.2023.10.006_bb0005","doi-asserted-by":"crossref","first-page":"114152","DOI":"10.1016\/j.bbr.2022.114152","article-title":"Underlying differences in resting-state activity metrics related to sensitivity to punishment","volume":"437","author":"Adri\u00e1n-Ventura","year":"2023","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.jad.2023.10.006_bb0010","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/j.neubiorev.2021.10.017","article-title":"Alterations in large-scale functional networks in adult posttraumatic stress disorder: a systematic review and meta-analysis of resting-state functional connectivity studies","volume":"131","author":"Bao","year":"2021","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"6","key":"10.1016\/j.jad.2023.10.006_bb0015","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1002\/da.23252","article-title":"Reduced cortical volume of the default mode network in adolescents with generalized anxiety disorder","volume":"39","author":"Bashford-Largo","year":"2022","journal-title":"Depress. Anxiety"},{"issue":"1","key":"10.1016\/j.jad.2023.10.006_bb0020","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1093\/psyrad\/kkab003","article-title":"A review of resting-state fMRI and its use to examine psychiatric disorders","volume":"1","author":"Canario","year":"2021","journal-title":"Psychoradiology"},{"issue":"5","key":"10.1016\/j.jad.2023.10.006_bb0025","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1002\/hipo.22566","article-title":"Abnormal hippocampal structure and function in clinical anxiety and comorbid depression","volume":"26","author":"Cha","year":"2016","journal-title":"Hippocampus"},{"issue":"2","key":"10.1016\/j.jad.2023.10.006_bb0030","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1176\/appi.ajp.2020.19111153","article-title":"The overlapping neurobiology of induced and pathological anxiety: a meta-analysis of functional neural activation","volume":"178","author":"Chavanne","year":"2021","journal-title":"Am. J. Psychiatry"},{"issue":"8","key":"10.1016\/j.jad.2023.10.006_bb0035","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1093\/scan\/nsab129","article-title":"Stress-related hippocampus activation mediates the association between polyvictimization and trait anxiety in adolescents","volume":"17","author":"Corr","year":"2022","journal-title":"Soc. Cogn. Affect. Neurosci."},{"issue":"4","key":"10.1016\/j.jad.2023.10.006_bb0040","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1002\/hbm.23113","article-title":"Differential alterations of resting-state functional connectivity in generalized anxiety disorder and panic disorder","volume":"37","author":"Cui","year":"2016","journal-title":"Hum. Brain Mapp."},{"issue":"1","key":"10.1016\/j.jad.2023.10.006_bb0045","doi-asserted-by":"crossref","DOI":"10.1192\/j.eurpsy.2020.57","article-title":"Transdiagnostic and disease-specific abnormalities in the default-mode network hubs in psychiatric disorders: a meta-analysis of resting-state functional imaging studies","volume":"63","author":"Doucet","year":"2020","journal-title":"Eur. Psychiatry"},{"issue":"3","key":"10.1016\/j.jad.2023.10.006_bb0050","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0887-6185(01)00060-3","article-title":"State and trait anxiety revisited","volume":"15","author":"Endler","year":"2001","journal-title":"J. Anxiety Disord."},{"issue":"4","key":"10.1016\/j.jad.2023.10.006_bb0055","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/j.neuron.2013.06.016","article-title":"BLA to vHPC inputs modulate anxiety-related behaviors","volume":"79","author":"Felix-Ortiz","year":"2013","journal-title":"Neuron"},{"issue":"5","key":"10.1016\/j.jad.2023.10.006_bb0060","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1007\/s11682-019-00067-x","article-title":"Postchemotherapy hippocampal functional connectivity patterns in patients with breast cancer: a longitudinal resting state functional MR imaging study","volume":"14","author":"Feng","year":"2020","journal-title":"Brain Imaging Behav."},{"issue":"2","key":"10.1016\/j.jad.2023.10.006_bb0065","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.neuroimage.2012.01.021","article-title":"FreeSurfer","volume":"62","author":"Fischl","year":"2012","journal-title":"Neuroimage"},{"issue":"1","key":"10.1016\/j.jad.2023.10.006_bb0070","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0191-8869(02)00020-X","article-title":"Generalised anxiety disorder: relationships with Eysenck\u2019s, Gray\u2019s and Newman\u2019s theories","volume":"34","author":"Gomez","year":"2003","journal-title":"Pers. Individ. Differ."},{"key":"10.1016\/j.jad.2023.10.006_bb0075","series-title":"The Neuropsychology of Anxiety. An Enquiry into the Functions of the Septo-Hippocampal System","author":"Gray","year":"1982"},{"key":"10.1016\/j.jad.2023.10.006_bb0080","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.e7500","article-title":"Generalized anxiety disorder: diagnosis and treatment","volume":"345","author":"Hoge","year":"2012","journal-title":"BMJ"},{"issue":"1101","key":"10.1016\/j.jad.2023.10.006_bb0085","doi-asserted-by":"crossref","first-page":"20181000","DOI":"10.1259\/bjr.20181000","article-title":"Progress in psychoradiology, the clinical application of psychiatric neuroimaging","volume":"92","author":"Huang","year":"2019","journal-title":"Br. J. Radiol."},{"issue":"10","key":"10.1016\/j.jad.2023.10.006_bb0090","doi-asserted-by":"crossref","DOI":"10.1111\/psyp.13629","article-title":"The effect of trait anxiety on risk-taking: functional coupling between right hippocampus and left insula","volume":"57","author":"Huo","year":"2020","journal-title":"Psychophysiology"},{"issue":"1","key":"10.1016\/j.jad.2023.10.006_bb0095","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1186\/s12888-022-04127-3","article-title":"Effects of group mindfulness-based cognitive therapy and group cognitive behavioural therapy on symptomatic generalized anxiety disorder: a randomized controlled noninferiority trial","volume":"22","author":"Jiang","year":"2022","journal-title":"BMC Psychiatry"},{"issue":"5","key":"10.1016\/j.jad.2023.10.006_bb0100","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1038\/sj.npp.1300910","article-title":"Anxiety and hippocampus volume in the rat","volume":"31","author":"Kalisch","year":"2006","journal-title":"Neuropsychopharmacology"},{"issue":"7","key":"10.1016\/j.jad.2023.10.006_bb0105","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1093\/cercor\/bhq237","article-title":"Anxiety dissociates dorsal and ventral medial prefrontal cortex functional connectivity with the amygdala at rest","volume":"21","author":"Kim","year":"2011","journal-title":"Cereb. Cortex"},{"issue":"6","key":"10.1016\/j.jad.2023.10.006_bb0110","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1016\/j.cell.2018.10.005","article-title":"An amygdala\u2013hippocampus subnetwork that encodes variation in human mood","volume":"175","author":"Kirkby","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.jad.2023.10.006_bb0115","doi-asserted-by":"crossref","first-page":"102016","DOI":"10.1016\/j.nicl.2019.102016","article-title":"Systematic review and meta-analyses of neural structural and functional differences in generalized anxiety disorder and healthy controls using magnetic resonance imaging","volume":"24","author":"Kolesar","year":"2019","journal-title":"Neuroimage Clin"},{"issue":"4","key":"10.1016\/j.jad.2023.10.006_bb0120","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.cub.2016.12.048","article-title":"The brain basis for misophonia","volume":"27","author":"Kumar","year":"2017","journal-title":"Curr. Biol."},{"issue":"1","key":"10.1016\/j.jad.2023.10.006_bb0125","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1186\/s12888-020-02831-6","article-title":"Emotion reactivity-related brain network analysis in generalized anxiety disorder: a task fMRI study","volume":"20","author":"Li","year":"2020","journal-title":"BMC Psychiatry"},{"key":"10.1016\/j.jad.2023.10.006_bb0130","doi-asserted-by":"crossref","first-page":"104574","DOI":"10.1016\/j.neubiorev.2022.104574","article-title":"Abnormal resting-state functional connectivity in patients with obsessive-compulsive disorder: a systematic review and meta-analysis","volume":"135","author":"Liu","year":"2022","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.jad.2023.10.006_bb0135","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.pscychresns.2019.03.001","article-title":"Frontoparietal network abnormalities of gray matter volume and functional connectivity in patients with generalized anxiety disorder","volume":"286","author":"Ma","year":"2019","journal-title":"Psychiatry Research-Neuroimaging"},{"issue":"1","key":"10.1016\/j.jad.2023.10.006_bb0140","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/0165-0327(88)90072-9","article-title":"The Hamilton anxiety scale: reliability, validity, and sensitivity to change in anxiety and depressive disorders","volume":"14","author":"Maier","year":"1988","journal-title":"J. Affect. Disord."},{"issue":"6","key":"10.1016\/j.jad.2023.10.006_bb0145","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1176\/ajp.2006.163.6.1091","article-title":"Ventrolateral prefrontal cortex activation and attentional bias in response to angry faces in adolescents with generalized anxiety disorder","volume":"163","author":"Monk","year":"2006","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.jad.2023.10.006_bb0150","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.jad.2015.07.038","article-title":"Explicit verbal memory impairments associated with brain functional deficits and morphological alterations in patients with generalized anxiety disorder","volume":"186","author":"Moon","year":"2015","journal-title":"J. Affect. Disord."},{"issue":"1","key":"10.1016\/j.jad.2023.10.006_bb0155","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1037\/a0018055","article-title":"Meta-analysis of the relations of anxiety sensitivity to the depressive and anxiety disorders","volume":"136","author":"Naragon-Gainey","year":"2010","journal-title":"Psychol. Bull."},{"issue":"10","key":"10.1016\/j.jad.2023.10.006_bb0160","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1016\/S0006-3223(00)00920-3","article-title":"Regional cerebral metabolism associated with anxiety symptoms in affective disorder patients","volume":"48","author":"Osuch","year":"2000","journal-title":"Biol. Psychiatry"},{"issue":"8","key":"10.1016\/j.jad.2023.10.006_bb0165","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.1038\/npp.2017.56","article-title":"Bidirectional control of anxiety-related behaviors in mice: role of inputs arising from the ventral hippocampus to the lateral septum and medial prefrontal cortex","volume":"42","author":"Parfitt","year":"2017","journal-title":"Neuropsychopharmacology"},{"issue":"4","key":"10.1016\/j.jad.2023.10.006_bb0170","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.biopsych.2006.03.042","article-title":"An insular view of anxiety","volume":"60","author":"Paulus","year":"2006","journal-title":"Biol. Psychiatry"},{"issue":"5\u20136","key":"10.1016\/j.jad.2023.10.006_bb0175","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1007\/s00429-010-0258-9","article-title":"Interoception in anxiety and depression","volume":"214","author":"Paulus","year":"2010","journal-title":"Brain Struct. Funct."},{"issue":"5","key":"10.1016\/j.jad.2023.10.006_bb0180","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/S0006-3223(03)00168-9","article-title":"Neurobiology of emotion perception I: the neural basis of normal emotion perception","volume":"54","author":"Phillips","year":"2003","journal-title":"Biol. Psychiatry"},{"issue":"4","key":"10.1016\/j.jad.2023.10.006_bb0185","doi-asserted-by":"crossref","first-page":"717","DOI":"10.3758\/BF03206553","article-title":"SPSS and SAS procedures for estimating indirect effects in simple mediation models","volume":"36","author":"Preacher","year":"2004","journal-title":"Behav. Res. Methods Instrum. Comput."},{"issue":"2","key":"10.1016\/j.jad.2023.10.006_bb0190","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S0887-6185(97)00006-6","article-title":"Trait anxiety: It\u2019s not what you think it is","volume":"11","author":"Reiss","year":"1997","journal-title":"J. Anxiety Disord."},{"issue":"10","key":"10.1016\/j.jad.2023.10.006_bb0195","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1038\/mp.2009.15","article-title":"Adult hippocampal neurogenesis is involved in anxiety-related behaviors","volume":"14","author":"Revest","year":"2009","journal-title":"Mol. Psychiatry"},{"issue":"4","key":"10.1016\/j.jad.2023.10.006_bb0200","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/s00406-010-0147-5","article-title":"Localized gray matter volume abnormalities in generalized anxiety disorder","volume":"261","author":"Schienle","year":"2011","journal-title":"Eur. Arch. Psychiatry Clin. Neurosci."},{"issue":"4","key":"10.1016\/j.jad.2023.10.006_bb0205","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/BF00960624","article-title":"Reliability and factorial structure of the Chinese version of the state-trait anxiety inventory","volume":"10","author":"Shek","year":"1988","journal-title":"J. Psychopathol. Behav. Assess."},{"issue":"7","key":"10.1016\/j.jad.2023.10.006_bb0210","first-page":"493","article-title":"Evaluation of the reliability and validity of Chinese version of the Mini-international neuropsychiatric interview in patients with mental disorders","volume":"23","author":"Si","year":"2009","journal-title":"Chin. Ment. Health J."},{"issue":"9","key":"10.1016\/j.jad.2023.10.006_bb0215","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0025031","article-title":"REST: a toolkit for resting-state functional magnetic resonance imaging data processing","volume":"6","author":"Song","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.jad.2023.10.006_bb0220","series-title":"Anxiety and Behavior","first-page":"3","article-title":"Theory and research on anxiety","author":"Spielberger","year":"1966"},{"issue":"10","key":"10.1016\/j.jad.2023.10.006_bb0225","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1001\/archinte.166.10.1092","article-title":"A brief measure for assessing generalized anxiety disorder: the GAD-7","volume":"166","author":"Spitzer","year":"2006","journal-title":"Arch. Intern. Med."},{"issue":"11","key":"10.1016\/j.jad.2023.10.006_bb0230","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1002\/da.21961","article-title":"Neurocircuitry of generalized anxiety disorder in adolescents: a pilot functional neuroimaging and functional connectivity study","volume":"29","author":"Strawn","year":"2012","journal-title":"Depress. Anxiety"},{"key":"10.1016\/j.jad.2023.10.006_bb0235","doi-asserted-by":"crossref","DOI":"10.3389\/fnhum.2020.00204","article-title":"Differential functional connectivity in anterior and posterior Hippocampus supporting the development of memory formation","volume":"14","author":"Tang","year":"2020","journal-title":"Front. Hum. Neurosci."},{"issue":"7","key":"10.1016\/j.jad.2023.10.006_bb0240","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1093\/occmed\/kqv054","article-title":"Hamilton rating scale for anxiety (HAM-A)","volume":"65","author":"Thompson","year":"2015","journal-title":"Occup. Med."},{"issue":"1","key":"10.1016\/j.jad.2023.10.006_bb0245","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/nrn3857","article-title":"Salience processing and insular cortical function and dysfunction","volume":"16","author":"Uddin","year":"2015","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.jad.2023.10.006_bb0250","first-page":"758978","article-title":"Dysfunction of resting-state functional connectivity of amygdala subregions in drug-na\u00efve patients with generalized anxiety disorder","volume":"12","author":"Wang","year":"2021","journal-title":"Front. Psychol."},{"key":"10.1016\/j.jad.2023.10.006_bb0255","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.neulet.2016.05.005","article-title":"Aberrant regional neural fluctuations and functional connectivity in generalized anxiety disorder revealed by resting-state functional magnetic resonance imaging","volume":"624","author":"Wang","year":"2016","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.jad.2023.10.006_bb6000","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.neuroimage.2013.03.004","article-title":"A comprehensive assessment of regional variation in the impact of head micromovements on functional connectomics","volume":"76","author":"Yan","year":"2013","journal-title":"Neuroimage"},{"issue":"3","key":"10.1016\/j.jad.2023.10.006_bb0260","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1007\/s12021-016-9299-4","article-title":"DPABI: Data Processing & Analysis for (resting-state) brain imaging","volume":"14","author":"Yan","year":"2016","journal-title":"Neuroinformatics"},{"key":"10.1016\/j.jad.2023.10.006_bb0265","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.jad.2018.02.012","article-title":"Generalized anxiety disorder in urban China: prevalence, awareness, and disease burden","volume":"234","author":"Yu","year":"2018","journal-title":"J. Affect. Disord."},{"issue":"16","key":"10.1016\/j.jad.2023.10.006_bb0270","doi-asserted-by":"crossref","first-page":"3094","DOI":"10.1523\/JNEUROSCI.2451-18.2018","article-title":"Glutamate within the marmoset anterior Hippocampus interacts with area 25 to regulate the behavioral and cardiovascular correlates of high-trait anxiety","volume":"39","author":"Zeredo","year":"2019","journal-title":"J. Neurosci."},{"issue":"5","key":"10.1016\/j.jad.2023.10.006_bb0275","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1002\/hbm.25754","article-title":"The anxiety-specific hippocampus-prefrontal cortex pathways links to procrastination through self-control","volume":"43","author":"Zhang","year":"2022","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.jad.2023.10.006_bb0280","article-title":"Aberrant intrinsic hippocampal and orbitofrontal connectivity in drug-naive adolescent patients with major depressive disorder","author":"Zhou","year":"2022","journal-title":"Eur. Child Adolesc. Psychiatry"},{"issue":"6","key":"10.1016\/j.jad.2023.10.006_bb0285","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/S0033-3182(71)71479-0","article-title":"A rating instrument for anxiety disorders","volume":"12","author":"Zung","year":"1971","journal-title":"Psychosomatics"}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032723011874?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032723011874?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T04:07:04Z","timestamp":1759032424000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165032723011874"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":58,"alternative-id":["S0165032723011874"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2023.10.006","relation":{},"ISSN":["0165-0327"],"issn-type":[{"value":"0165-0327","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Trait anxiety mediates the association between hippocampal\u2013insula functional connectivity and anxiety symptom severity in adults with and without generalized anxiety disorder","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2023.10.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}