{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T19:47:05Z","timestamp":1791229625931,"version":"4.1.0"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100017959","name":"Hebei Province Health Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017959","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81801344"],"award-info":[{"award-number":["81801344"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82171530"],"award-info":[{"award-number":["82171530"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.jad.2024.08.162","type":"journal-article","created":{"date-parts":[[2024,8,26]],"date-time":"2024-08-26T22:50:32Z","timestamp":1724712632000},"page":"370-378","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Association between blood mitochondrial DNA copy number and mental disorders: A bidirectional two-sample mendelian randomization study"],"prefix":"10.1016","volume":"366","author":[{"given":"Yan\u2019e","family":"Lu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingxing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaotong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinlei","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunyi","family":"Lan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shumin","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhendong","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lulu","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naixue","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya Bin","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia Jia","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jad.2024.08.162_bb0005","doi-asserted-by":"crossref","first-page":"369","DOI":"10.3390\/nu10030369","article-title":"Comprehensive nutritional and dietary intervention for autism Spectrum disorder-a randomized, controlled 12-month trial","volume":"10","author":"Adams","year":"2018","journal-title":"Nutrients"},{"key":"10.1016\/j.jad.2024.08.162_bb0010","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/754946","article-title":"High glucose-induced oxidative stress increases the copy number of mitochondrial DNA in human mesangial cells","volume":"2013","author":"Al-Kafaji","year":"2013","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.jad.2024.08.162_bb0015","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1002\/wps.21034","article-title":"New insights from the last decade of research in psychiatric genetics: discoveries, challenges and clinical implications","volume":"22","author":"Andreassen","year":"2023","journal-title":"World Psychiatry"},{"key":"10.1016\/j.jad.2024.08.162_bb0020","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1111\/opo.12131","article-title":"When to use the Bonferroni correction","volume":"34","author":"Armstrong","year":"2014","journal-title":"Ophthalmic Physiol. Opt."},{"key":"10.1016\/j.jad.2024.08.162_bb0025","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1093\/icvts\/ivy163","article-title":"Statistical primer: heterogeneity, random- or fixed-effects model analyses?","volume":"27","author":"Barili","year":"2018","journal-title":"Interact. Cardiovasc. Thorac. Surg."},{"key":"10.1016\/j.jad.2024.08.162_bb0030","doi-asserted-by":"crossref","first-page":"18406","DOI":"10.1074\/jbc.REV120.011202","article-title":"Structure, mechanism, and regulation of mitochondrial DNA transcription initiation","volume":"295","author":"Basu","year":"2020","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jad.2024.08.162_bb0035","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1093\/ije\/dyv080","article-title":"Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression","volume":"44","author":"Bowden","year":"2015","journal-title":"Int. J. Epidemiol."},{"key":"10.1016\/j.jad.2024.08.162_bb0040","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1093\/ije\/dyy258","article-title":"Improving the accuracy of two-sample summary-data Mendelian randomization: moving beyond the NOME assumption","volume":"48","author":"Bowden","year":"2019","journal-title":"Int. J. Epidemiol."},{"key":"10.1016\/j.jad.2024.08.162_bb0045","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1002\/jrsm.1346","article-title":"Meta-analysis and Mendelian randomization: a review","volume":"10","author":"Bowden","year":"2019","journal-title":"Res. Synth. Methods"},{"key":"10.1016\/j.jad.2024.08.162_bb0050","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1136\/jech-2017-210000","article-title":"Causal associations between body mass index and mental health: a Mendelian randomisation study","volume":"72","author":"van den Broek","year":"2018","journal-title":"J. Epidemiol. Community Health"},{"key":"10.1016\/j.jad.2024.08.162_bb0055","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1097\/EDE.0000000000000559","article-title":"Sensitivity analyses for robust causal inference from Mendelian randomization analyses with multiple genetic variants","volume":"28","author":"Burgess","year":"2017","journal-title":"Epidemiology"},{"key":"10.1016\/j.jad.2024.08.162_bb0060","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2022.953762","article-title":"Dissecting the multifaceted contribution of the mitochondrial genome to autism spectrum disorder","volume":"13","author":"Caporali","year":"2022","journal-title":"Front. Genet."},{"key":"10.1016\/j.jad.2024.08.162_bb0065","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.mito.2020.06.004","article-title":"Thinking outside the nucleus: mitochondrial DNA copy number in health and disease","volume":"53","author":"Castellani","year":"2020","journal-title":"Mitochondrion"},{"key":"10.1016\/j.jad.2024.08.162_bb0070","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.pnpbp.2018.12.015","article-title":"Mitochondrial function and abnormalities implicated in the pathogenesis of ASD","volume":"92","author":"Castora","year":"2019","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.jad.2024.08.162_bb0075","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/s12888-015-0432-y","article-title":"Elevated mitochondrial DNA copy number in peripheral blood cells is associated with childhood autism","volume":"15","author":"Chen","year":"2015","journal-title":"BMC Psychiatry"},{"key":"10.1016\/j.jad.2024.08.162_bb0080","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.70382","article-title":"GWAS and ExWAS of blood mitochondrial DNA copy number identifies 71 loci and highlights a potential causal role in dementia","volume":"11","author":"Chong","year":"2022","journal-title":"Elife"},{"key":"10.1016\/j.jad.2024.08.162_bb0085","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S1673-8527(08)60099-5","article-title":"Number matters: control of mammalian mitochondrial DNA copy number","volume":"36","author":"Clay Montier","year":"2009","journal-title":"J. Genet. Genomics"},{"issue":"Suppl. 1","key":"10.1016\/j.jad.2024.08.162_bb0090","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1080\/10408398.2010.526838","article-title":"Overview of the epidemiology methods and applications: strengths and limitations of observational study designs","volume":"50","author":"Colditz","year":"2010","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.jad.2024.08.162_bb0095","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/S0006-3223(98)00043-2","article-title":"Multiple correlations and Bonferroni\u2019s correction","volume":"44","author":"Curtin","year":"1998","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2024.08.162_bb0100","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1038\/s41588-018-0269-7","article-title":"Discovery of the first genome-wide significant risk loci for attention deficit\/hyperactivity disorder","volume":"51","author":"Demontis","year":"2019","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jad.2024.08.162_bb0105","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1002\/1873-3468.14021","article-title":"Mitochondrial DNA copy number in human disease: the more the better?","volume":"595","author":"Filograna","year":"2021","journal-title":"FEBS Lett."},{"key":"10.1016\/j.jad.2024.08.162_bb0110","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1038\/cdd.2014.150","article-title":"Oxidative stress and autophagy: the clash between damage and metabolic needs","volume":"22","author":"Filomeni","year":"2015","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.jad.2024.08.162_bb0115","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/S2215-0366(20)30136-X","article-title":"Sleep disturbance and psychiatric disorders","volume":"7","author":"Freeman","year":"2020","journal-title":"Lancet Psychiatry"},{"key":"10.1016\/j.jad.2024.08.162_bb0120","first-page":"137","article-title":"Mental disorders collaborators, 2022. Global, regional, and national burden of 12 mental disorders in 204 countries and territories, 1990-2019: a systematic analysis for the global burden of disease study 2019","volume":"9","author":"GBD","year":"2019","journal-title":"Lancet Psychiatry"},{"key":"10.1016\/j.jad.2024.08.162_bb0125","article-title":"Systematic review of mitochondrial genetic variation in attention-deficit\/hyperactivity disorder","author":"Giannoulis","year":"2022","journal-title":"Eur. Child Adolesc. Psychiatry"},{"key":"10.1016\/j.jad.2024.08.162_bb0130","doi-asserted-by":"crossref","first-page":"359","DOI":"10.3389\/fncel.2017.00359","article-title":"Fundamental elements in autism: from neurogenesis and neurite growth to synaptic plasticity","volume":"11","author":"Gilbert","year":"2017","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.jad.2024.08.162_bb0135","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1038\/s41588-019-0344-8","article-title":"Identification of common genetic risk variants for autism spectrum disorder","volume":"51","author":"Grove","year":"2019","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jad.2024.08.162_bb0140","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1017\/S0033291707002000","article-title":"Alcohol consumption as a risk factor for non-recovery from common mental disorder: results from the longitudinal follow-up of the National Psychiatric Morbidity Survey","volume":"38","author":"Haynes","year":"2008","journal-title":"Psychol. Med."},{"key":"10.1016\/j.jad.2024.08.162_bb0145","article-title":"Leukocyte mitochondrial DNA copy number in blood is not associated with major depressive disorder in young adults","volume":"9","author":"He","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.jad.2024.08.162_bb0150","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1038\/s41593-018-0326-7","article-title":"Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions","volume":"22","author":"Howard","year":"2019","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.jad.2024.08.162_bb0155","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1038\/mp.2017.154","article-title":"Revealing the complex genetic architecture of obsessive-compulsive disorder using meta-analysis","volume":"23","year":"2018","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jad.2024.08.162_bb0160","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.nbd.2015.07.007","article-title":"Cellular and molecular introduction to brain development","volume":"92","author":"Jiang","year":"2016","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.jad.2024.08.162_bb0165","doi-asserted-by":"crossref","first-page":"E451","DOI":"10.1503\/jpn.200238","article-title":"Alterations of cellular aging markers in obsessive- compulsive disorder: mitochondrial DNA copy number and telomere length","volume":"46","author":"Kang","year":"2021","journal-title":"J. Psychiatry Neurosci."},{"key":"10.1016\/j.jad.2024.08.162_bb0170","doi-asserted-by":"crossref","first-page":"2653","DOI":"10.1242\/jcs.01134","article-title":"Organization and dynamics of human mitochondrial DNA","volume":"117","author":"Legros","year":"2004","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.jad.2024.08.162_bb0175","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0228166","article-title":"Evaluation of mitochondrial DNA copy number estimation techniques","volume":"15","author":"Longchamps","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.jad.2024.08.162_bb0180","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s00439-021-02394-w","article-title":"Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation","volume":"141","author":"Longchamps","year":"2022","journal-title":"Hum. Genet."},{"key":"10.1016\/j.jad.2024.08.162_bb0185","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/j.neuron.2015.03.035","article-title":"A cellular perspective on brain energy metabolism and functional imaging","volume":"86","author":"Magistretti","year":"2015","journal-title":"Neuron"},{"key":"10.1016\/j.jad.2024.08.162_bb0190","doi-asserted-by":"crossref","first-page":"4262","DOI":"10.3390\/molecules24234262","article-title":"Effects of l-carnitine in patients with autism Spectrum disorders: review of clinical studies","volume":"24","author":"Malaguarnera","year":"2019","journal-title":"Molecules"},{"key":"10.1016\/j.jad.2024.08.162_bb0195","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1385\/NMM:2:2:215","article-title":"Energetics and oxidative stress in synaptic plasticity and neurodegenerative disorders","volume":"2","author":"Mattson","year":"2002","journal-title":"NeuroMolecular Med."},{"key":"10.1016\/j.jad.2024.08.162_bb0200","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1001\/jamapsychiatry.2022.2196","article-title":"Association between brain structure and alcohol use behaviors in adults","volume":"79","author":"Mavromatis","year":"2022","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.jad.2024.08.162_bb0205","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.psychres.2018.03.061","article-title":"Coenzyme Q10 supplementation reduces oxidative stress and decreases antioxidant enzyme activity in children with autism spectrum disorders","volume":"265","author":"Mousavinejad","year":"2018","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.jad.2024.08.162_bb0210","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1038\/s41588-021-00857-4","article-title":"Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology","volume":"53","author":"Mullins","year":"2021","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jad.2024.08.162_bb0215","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.2174\/1570159X21666221121095618","article-title":"Treatment of autism Spectrum disorders by mitochondrial-targeted drug: future of neurological diseases therapeutics","volume":"21","author":"Nabi","year":"2023","journal-title":"Curr. Neuropharmacol."},{"key":"10.1016\/j.jad.2024.08.162_bb0220","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1038\/s41576-018-0020-3","article-title":"Using genetic data to strengthen causal inference in observational research","volume":"19","author":"Pingault","year":"2018","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.jad.2024.08.162_bb0225","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/s13073-020-00734-5","article-title":"Translating insights from neuropsychiatric genetics and genomics for precision psychiatry","volume":"12","author":"Rees","year":"2020","journal-title":"Genome Med."},{"key":"10.1016\/j.jad.2024.08.162_bb0230","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1007\/s11920-019-0997-0","article-title":"Global burden of disease and the impact of mental and addictive disorders","volume":"21","author":"Rehm","year":"2019","journal-title":"Curr. Psychiatry Rep."},{"key":"10.1016\/j.jad.2024.08.162_bb0235","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1007\/s40291-018-0352-x","article-title":"Clinical and molecular characteristics of mitochondrial dysfunction in autism Spectrum disorder","volume":"22","author":"Rose","year":"2018","journal-title":"Mol. Diagn. Ther."},{"key":"10.1016\/j.jad.2024.08.162_bb0240","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1001\/jamapsychiatry.2020.3554","article-title":"Prescription opioid use and risk for major depressive disorder and anxiety and stress-related disorders: a multivariable Mendelian randomization analysis","volume":"78","author":"Rosoff","year":"2021","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.jad.2024.08.162_bb0245","doi-asserted-by":"crossref","DOI":"10.1016\/j.pnpbp.2022.110656","article-title":"Whole blood mitochondrial DNA copy number in depression and response to electroconvulsive therapy","volume":"121","author":"Ryan","year":"2023","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.jad.2024.08.162_bb0250","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s43586-021-00091-6","volume":"2","author":"Sanderson","year":"2022","journal-title":"Mendelian randomization. Nat Rev Methods Primers"},{"key":"10.1016\/j.jad.2024.08.162_bb0255","doi-asserted-by":"crossref","first-page":"3253","DOI":"10.1681\/ASN.2016010098","article-title":"Mendelian randomization as an approach to assess causality using observational data","volume":"27","author":"Sekula","year":"2016","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.jad.2024.08.162_bb0260","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1213\/ANE.0000000000000861","article-title":"Clinical research methodology 2: observational clinical research","volume":"121","author":"Sessler","year":"2015","journal-title":"Anesth. Analg."},{"key":"10.1016\/j.jad.2024.08.162_bb0265","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajp.2020.102193","article-title":"Leukocyte mitochondrial DNA copy number in schizophrenia","volume":"53","author":"Shivakumar","year":"2020","journal-title":"Asian J. Psychiatr."},{"key":"10.1016\/j.jad.2024.08.162_bb0270","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1002\/acn3.51034","article-title":"Developmental regression and mitochondrial function in children with autism","volume":"7","author":"Singh","year":"2020","journal-title":"Ann. Clin. Transl. Neurol."},{"key":"10.1016\/j.jad.2024.08.162_bb0275","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1001\/jama.2021.18236","article-title":"Strengthening the reporting of observational studies in epidemiology using Mendelian randomization: the STROBE-MR statement","volume":"326","author":"Skrivankova","year":"2021","journal-title":"JAMA"},{"key":"10.1016\/j.jad.2024.08.162_bb0280","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijchp.2022.100335","article-title":"An application of the stress-diathesis model: a review about the association between smoking tobacco, smoking cessation, and mental health","volume":"23","author":"Taylor","year":"2023","journal-title":"Int. J. Clin. Health Psychol."},{"key":"10.1016\/j.jad.2024.08.162_bb0285","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1038\/s41586-022-04434-5","article-title":"Mapping genomic loci implicates genes and synaptic biology in schizophrenia","volume":"604","author":"Trubetskoy","year":"2022","journal-title":"Nature"},{"key":"10.1016\/j.jad.2024.08.162_bb0290","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1093\/hmg\/ddy009","article-title":"Genetic and clinical evidence of mitochondrial dysfunction in autism spectrum disorder and intellectual disability","volume":"27","author":"Valiente-Pallej\u00e0","year":"2018","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.jad.2024.08.162_bb0295","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1038\/mp.2017.48","article-title":"Depression, telomeres and mitochondrial DNA: between- and within-person associations from a 10-year longitudinal study","volume":"23","author":"Verhoeven","year":"2018","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jad.2024.08.162_bb0300","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1001\/jamapsychiatry.2014.2502","article-title":"Mortality in mental disorders and global disease burden implications: a systematic review and meta-analysis","volume":"72","author":"Walker","year":"2015","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.jad.2024.08.162_bb0305","article-title":"Circulating brain-derived neurotrophic factor, antioxidant enzymes activities, and mitochondrial DNA in bipolar disorder: an exploratory report","volume":"11","author":"Wang","year":"2020","journal-title":"Front. Psychol."},{"key":"10.1016\/j.jad.2024.08.162_bb0310","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.jad.2022.04.064","article-title":"The association of mitochondrial DNA copy number with incident mental disorders in women: a population-based follow-up study","volume":"308","author":"Wang","year":"2022","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2024.08.162_bb0315","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/j.euroneuro.2017.06.001","article-title":"Association of mitochondrial DNA in peripheral blood with depression, anxiety and stress- and adjustment disorders in primary health care patients","volume":"27","author":"Wang","year":"2017","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.jad.2024.08.162_bb0320","doi-asserted-by":"crossref","first-page":"3790","DOI":"10.1038\/s41467-022-30805-7","article-title":"Association of mitochondrial DNA content, heteroplasmies and inter-generational transmission with autism","volume":"13","author":"Wang","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jad.2024.08.162_bb0325","doi-asserted-by":"crossref","first-page":"2491","DOI":"10.1021\/acs.chemrestox.0c00083","article-title":"Mitochondrial DNA damage: prevalence, biological consequence, and emerging pathways","volume":"33","author":"Zhao","year":"2020","journal-title":"Chem. Res. Toxicol."}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016503272401396X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016503272401396X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,14]],"date-time":"2024-09-14T14:45:07Z","timestamp":1726325107000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016503272401396X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":65,"alternative-id":["S016503272401396X"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2024.08.162","relation":{},"ISSN":["0165-0327"],"issn-type":[{"value":"0165-0327","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association between blood mitochondrial DNA copy number and mental disorders: A bidirectional two-sample mendelian randomization study","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2024.08.162","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}