{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T17:15:23Z","timestamp":1792602923808,"version":"4.5.0"},"reference-count":84,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,22]],"date-time":"2024-09-22T00:00:00Z","timestamp":1726963200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.jad.2024.09.132","type":"journal-article","created":{"date-parts":[[2024,9,21]],"date-time":"2024-09-21T06:25:23Z","timestamp":1726899923000},"page":"720-726","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Association of anxiety disorder, depression, and bipolar disorder with autoimmune thyroiditis: A bidirectional two-sample mendelian randomized study"],"prefix":"10.1016","volume":"368","author":[{"given":"Jingyang","family":"Su","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jialin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanyu","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinhua","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6395","key":"10.1016\/j.jad.2024.09.132_bb0005","article-title":"Analysis of shared heritability in common disorders of the brain","volume":"360","author":"Anttila","year":"2018","journal-title":"Science"},{"issue":"2","key":"10.1016\/j.jad.2024.09.132_bb0010","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1080\/17446651.2022.2052044","article-title":"Management of Graves\u2019 hyperthyroidism: present and future","volume":"17","author":"Bartalena","year":"2022","journal-title":"Expert. Rev. Endocrinol. Metab."},{"issue":"2","key":"10.1016\/j.jad.2024.09.132_bb0015","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1038\/mp.2014.186","article-title":"Levothyroxine effects on depressive symptoms and limbic glucose metabolism in bipolar disorder: a randomized, placebo-controlled positron emission tomography study","volume":"21","author":"Bauer","year":"2016","journal-title":"Mol. Psychiatry"},{"issue":"10","key":"10.1016\/j.jad.2024.09.132_bb0020","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1111\/j.1365-2826.2008.01774.x","article-title":"The thyroid-brain interaction in thyroid disorders and mood disorders","volume":"20","author":"Bauer","year":"2008","journal-title":"J. Neuroendocrinol."},{"issue":"2","key":"10.1016\/j.jad.2024.09.132_bb0025","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3109\/15622970109027495","article-title":"Thyroid hormone, neural tissue and mood modulation","volume":"2","author":"Bauer","year":"2001","journal-title":"World J. Biol. Psychiatry"},{"issue":"4","key":"10.1016\/j.jad.2024.09.132_bb0030","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.biopsych.2013.09.023","article-title":"The epidemiologic evidence linking autoimmune diseases and psychosis","volume":"75","author":"Benros","year":"2014","journal-title":"Biol. Psychiatry"},{"issue":"1","key":"10.1016\/j.jad.2024.09.132_bb0035","doi-asserted-by":"crossref","DOI":"10.1530\/ETJ-21-0024","article-title":"Cellular and molecular basis of thyroid autoimmunity","volume":"11","author":"Bogus\u0142awska","year":"2022","journal-title":"Eur Thyroid J."},{"issue":"1","key":"10.1016\/j.jad.2024.09.132_bb0040","doi-asserted-by":"crossref","first-page":"20260","DOI":"10.1038\/s41598-021-99732-9","article-title":"HLA-E circulating and genetic determinants in schizophrenia and bipolar disorder","volume":"11","author":"Boukouaci","year":"2021","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.jad.2024.09.132_bb0045","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1093\/ije\/dyv080","article-title":"Mendelian randomization with invalid instruments: effect estimation and bias detection through egger regression","volume":"44","author":"Bowden","year":"2015","journal-title":"Int. J. Epidemiol."},{"issue":"4","key":"10.1016\/j.jad.2024.09.132_bb0050","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1002\/gepi.21965","article-title":"Consistent estimation in Mendelian randomization with some invalid instruments using a weighted median estimator","volume":"40","author":"Bowden","year":"2016","journal-title":"Genet. Epidemiol."},{"issue":"3","key":"10.1016\/j.jad.2024.09.132_bb0055","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1093\/ije\/dyy258","article-title":"Improving the accuracy of two-sample summary-data Mendelian randomization: moving beyond the NOME assumption","volume":"48","author":"Bowden","year":"2019","journal-title":"Int. J. Epidemiol."},{"issue":"4","key":"10.1016\/j.jad.2024.09.132_bb0060","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1002\/jrsm.1346","article-title":"Meta-analysis and Mendelian randomization: a review","volume":"10","author":"Bowden","year":"2019","journal-title":"Res. Synth. Methods"},{"issue":"7","key":"10.1016\/j.jad.2024.09.132_bb0065","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1002\/gepi.21758","article-title":"Mendelian randomization analysis with multiple genetic variants using summarized data","volume":"37","author":"Burgess","year":"2013","journal-title":"Genet. Epidemiol."},{"issue":"3","key":"10.1016\/j.jad.2024.09.132_bb0070","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1093\/ije\/dyr036","article-title":"Avoiding bias from weak instruments in Mendelian randomization studies","volume":"40","author":"Burgess","year":"2011","journal-title":"Int. J. Epidemiol."},{"issue":"5","key":"10.1016\/j.jad.2024.09.132_bb0075","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/s10654-017-0255-x","article-title":"Interpreting findings from Mendelian randomization using the MR-egger method","volume":"32","author":"Burgess","year":"2017","journal-title":"Eur. J. Epidemiol."},{"issue":"23","key":"10.1016\/j.jad.2024.09.132_bb0080","doi-asserted-by":"crossref","first-page":"3689","DOI":"10.1016\/j.febslet.2011.04.032","article-title":"Why is PTPN22 a good candidate susceptibility gene for autoimmune disease?","volume":"585","author":"Burn","year":"2011","journal-title":"FEBS Lett."},{"key":"10.1016\/j.jad.2024.09.132_bb0085","doi-asserted-by":"crossref","DOI":"10.4061\/2011\/306367","article-title":"Thyroid functions and bipolar affective disorder","volume":"2011","author":"Chakrabarti","year":"2011","journal-title":"J. Thyroid. Res."},{"issue":"1","key":"10.1016\/j.jad.2024.09.132_bb0090","doi-asserted-by":"crossref","DOI":"10.1111\/tan.15173","article-title":"Associations of classical HLA alleles with depression and anxiety","volume":"103","author":"Cheng","year":"2024","journal-title":"Hla"},{"key":"10.1016\/j.jad.2024.09.132_bb0095","article-title":"T regulatory cells as a potential therapeutic target in psychosis? Current challenges and future perspectives","volume":"17","author":"Corsi-Zuelli","year":"2021","journal-title":"Brain Behav Immun Health."},{"issue":"5","key":"10.1016\/j.jad.2024.09.132_bb0100","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.jpsychores.2005.04.002","article-title":"Thyroid autoimmunity, depression and anxiety; are there any connections? An epidemiological study of a large population","volume":"59","author":"Engum","year":"2005","journal-title":"J. Psychosom. Res."},{"issue":"4","key":"10.1016\/j.jad.2024.09.132_bb0105","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1590\/1516-4446-2020-1111","article-title":"Ultra-long-term lithium therapy: all-important matters and a case of successful 50-year lithium treatment","volume":"43","author":"Ferensztajn-Rochowiak","year":"2021","journal-title":"Braz J Psychiatry."},{"issue":"3","key":"10.1016\/j.jad.2024.09.132_bb0110","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1080\/15622970500474739","article-title":"Peripheral thyroid dysfunction in depression","volume":"7","author":"Fountoulakis","year":"2006","journal-title":"World J. Biol. Psychiatry"},{"issue":"5","key":"10.1016\/j.jad.2024.09.132_bb0115","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.psyneuen.2009.10.005","article-title":"Decrease of CD4(+)FOXP3(+) T regulatory cells in the peripheral blood of human subjects undergoing a mental stressor","volume":"35","author":"Freier","year":"2010","journal-title":"Psychoneuroendocrinology"},{"issue":"6","key":"10.1016\/j.jad.2024.09.132_bb0120","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/j.euroneuro.2018.03.011","article-title":"Comorbid thyroid disease in patients with major depressive disorder - results from the European Group for the Study of resistant depression (GSRD)","volume":"28","author":"Fugger","year":"2018","journal-title":"Eur. Neuropsychopharmacol."},{"issue":"1","key":"10.1016\/j.jad.2024.09.132_bb0125","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1038\/s41398-020-01036-5","article-title":"Common and distinct patterns of intrinsic brain activity alterations in major depression and bipolar disorder: voxel-based meta-analysis","volume":"10","author":"Gong","year":"2020","journal-title":"Transl. Psychiatry"},{"issue":"2","key":"10.1016\/j.jad.2024.09.132_bb0130","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.psyneuen.2007.11.002","article-title":"Analysis of the anxiolytic-like effect of TRH and the response of amygdalar TRHergic neurons in anxiety","volume":"33","author":"Guti\u00e9rrez-Mariscal","year":"2008","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.jad.2024.09.132_bb0135","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/590648","article-title":"The link between thyroid function and depression","volume":"2012","author":"Hage","year":"2012","journal-title":"J. Thyroid. Res."},{"key":"10.1016\/j.jad.2024.09.132_bb0140","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2021.662243","article-title":"Lack of evidence for a relationship between the hypothalamus-pituitary-adrenal and the hypothalamus-pituitary-thyroid Axis in adolescent depression","volume":"12","author":"Hirtz","year":"2021","journal-title":"Front Endocrinol (Lausanne)."},{"issue":"2","key":"10.1016\/j.jad.2024.09.132_bb0145","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1210\/jcem.87.2.8182","article-title":"Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and nutrition examination survey (NHANES III)","volume":"87","author":"Hollowell","year":"2002","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"8","key":"10.1016\/j.jad.2024.09.132_bb0150","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0202258","article-title":"Association between subclinical thyroid dysfunction and depressive symptoms in the Korean adult population: the 2014 Korea National Health and nutrition examination survey","volume":"13","author":"Hong","year":"2018","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.jad.2024.09.132_bb0155","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1038\/s41593-018-0326-7","article-title":"Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions","volume":"22","author":"Howard","year":"2019","journal-title":"Nat. Neurosci."},{"issue":"8","key":"10.1016\/j.jad.2024.09.132_bb0160","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0073057","article-title":"Hyperthyroidism and risk for bipolar disorders: a nationwide population-based study","volume":"8","author":"Hu","year":"2013","journal-title":"PLoS One"},{"issue":"10","key":"10.1016\/j.jad.2024.09.132_bb0165","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1089\/thy.1998.8.951","article-title":"The thyroid axis and depression","volume":"8","author":"Jackson","year":"1998","journal-title":"Thyroid"},{"issue":"229","key":"10.1016\/j.jad.2024.09.132_bb0170","first-page":"654","article-title":"Prevalence of thyroid dysfunction among depression patients in a tertiary care Centre","volume":"58","author":"Kafle","year":"2020","journal-title":"JNMA J. Nepal Med. Assoc."},{"issue":"4","key":"10.1016\/j.jad.2024.09.132_bb0175","doi-asserted-by":"crossref","first-page":"423","DOI":"10.4183\/aeb.2019.423","article-title":"Association of FOXP3 gene variants with risk of HASHIMOTO\u2019S thyroiditis and correlation with anti-TPO antibody levels","volume":"15","author":"Kalantar","year":"2019","journal-title":"Acta Endocrinol (Buchar)."},{"issue":"5","key":"10.1016\/j.jad.2024.09.132_bb0180","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1017\/S0033291797005333","article-title":"The epidemiology of DSM-III-R bipolar I disorder in a general population survey","volume":"27","author":"Kessler","year":"1997","journal-title":"Psychol. Med."},{"key":"10.1016\/j.jad.2024.09.132_bb0185","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.psyneuen.2015.04.016","article-title":"Relationship between thyroid-stimulating hormone levels and risk of depression among the general population with normal free T4 levels","volume":"58","author":"Kim","year":"2015","journal-title":"Psychoneuroendocrinology"},{"issue":"4","key":"10.1016\/j.jad.2024.09.132_bb0190","article-title":"Depression and autoimmune hypothyroidism-their relationship and the effects of treating psychiatric and thyroid disorders on changes in clinical and biochemical parameters including BDNF and other cytokines-a","volume":"15","author":"Kotkowska","year":"2022","journal-title":"Systematic Review. Pharmaceuticals (Basel)."},{"issue":"2","key":"10.1016\/j.jad.2024.09.132_bb0195","first-page":"75","article-title":"Neurological and psychiatric disorders in thyroid dysfunctions. The role of nuclear medicine: SPECT and PET imaging","volume":"33","author":"Lass","year":"2008","journal-title":"Minerva Endocrinol."},{"issue":"7","key":"10.1016\/j.jad.2024.09.132_bb0200","doi-asserted-by":"crossref","first-page":"445","DOI":"10.3109\/08916934.2015.1045582","article-title":"Association between FOXP3 polymorphisms and susceptibility to autoimmune diseases: a meta-analysis","volume":"48","author":"Lee","year":"2015","journal-title":"Autoimmunity"},{"key":"10.1016\/j.jad.2024.09.132_bb0205","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.bbi.2014.03.008","article-title":"Cognitive and affective dysfunctions in autoimmune thyroiditis","volume":"41","author":"Leyhe","year":"2014","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.jad.2024.09.132_bb0210","doi-asserted-by":"crossref","first-page":"392","DOI":"10.3389\/fendo.2020.00392","article-title":"The association between Foxp3 polymorphisms and risk of Graves\u2019 disease: a systematic review and Meta-analysis of observational studies","volume":"11","author":"Li","year":"2020","journal-title":"Front Endocrinol (Lausanne)."},{"issue":"3","key":"10.1016\/j.jad.2024.09.132_bb0215","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.bbi.2010.10.024","article-title":"CTLA-4 confers a risk of recurrent schizophrenia, major depressive disorder and bipolar disorder in the Chinese Han population","volume":"25","author":"Liu","year":"2011","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.jad.2024.09.132_bb0220","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.bbi.2020.06.014","article-title":"Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders - findings from a Danish population-based study","volume":"91","author":"Liu","year":"2021","journal-title":"Brain Behav. Immun."},{"issue":"1","key":"10.1016\/j.jad.2024.09.132_bb0225","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/s12888-018-2006-2","article-title":"Association between subclinical hypothyroidism and depression: an updated systematic review and meta-analysis","volume":"19","author":"Loh","year":"2019","journal-title":"BMC Psychiatry"},{"issue":"4","key":"10.1016\/j.jad.2024.09.132_bb0230","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1176\/ajp.139.4.405","article-title":"Serum thyrotropin response to thyrotropin-releasing hormone in psychiatric patients: a review","volume":"139","author":"Loosen","year":"1982","journal-title":"Am. J. Psychiatry"},{"issue":"15","key":"10.1016\/j.jad.2024.09.132_bb0235","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1001\/jama.2013.285606","article-title":"Variation in rates of autoimmune thyroid disease by race\/ethnicity in US military personnel","volume":"311","author":"McLeod","year":"2014","journal-title":"Jama"},{"issue":"2","key":"10.1016\/j.jad.2024.09.132_bb0240","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1007\/s12020-012-9703-2","article-title":"The incidence and prevalence of thyroid autoimmunity","volume":"42","author":"McLeod","year":"2012","journal-title":"Endocrine"},{"issue":"4","key":"10.1016\/j.jad.2024.09.132_bb0245","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1210\/jc.2013-3589","article-title":"Thyroid function within the normal range and the risk of depression: a population-based cohort study","volume":"99","author":"Medici","year":"2014","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"3","key":"10.1016\/j.jad.2024.09.132_bb0250","first-page":"223","article-title":"Association of Human Leukocyte Antigens Class I and II with Graves\u2019 disease in Iranian population","volume":"14","author":"Mehraji","year":"2017","journal-title":"Iran. J. Immunol."},{"key":"10.1016\/j.jad.2024.09.132_bb0255","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajp.2020.102112","article-title":"CTLA4 mRNA expression in blood is lower in schizophrenia, but not in affective disorders","volume":"52","author":"Miyamoto","year":"2020","journal-title":"Asian J. Psychiatr."},{"issue":"8","key":"10.1016\/j.jad.2024.09.132_bb0260","doi-asserted-by":"crossref","first-page":"2363","DOI":"10.1158\/1078-0432.CCR-18-3980","article-title":"Depression stresses the immune response and promotes prostate Cancer growth","volume":"25","author":"Mohammadpour","year":"2019","journal-title":"Clin. Cancer Res."},{"issue":"6","key":"10.1016\/j.jad.2024.09.132_bb0265","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1038\/s41588-021-00857-4","article-title":"Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology","volume":"53","author":"Mullins","year":"2021","journal-title":"Nat. Genet."},{"issue":"1","key":"10.1016\/j.jad.2024.09.132_bb0270","doi-asserted-by":"crossref","first-page":"108","DOI":"10.3892\/br.2016.813","article-title":"Association of CTLA-4 gene polymorphisms -318C\/T and +49A\/G and Hashimoto\u2019s thyroidits in Zahedan","volume":"6","author":"Narooie-Nejad","year":"2017","journal-title":"Iran. Biomed Rep."},{"issue":"8","key":"10.1016\/j.jad.2024.09.132_bb0275","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1111\/bdi.12842","article-title":"Adjunctive thyroid hormone treatment in rapid cycling bipolar disorder: a double-blind placebo-controlled trial of levothyroxine (L-T4) and triiodothyronine (T3)","volume":"21","author":"Nu\u00f1ez","year":"2019","journal-title":"Bipolar Disord."},{"issue":"10","key":"10.1016\/j.jad.2024.09.132_bb0280","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1038\/mp.2015.197","article-title":"Meta-analysis of genome-wide association studies of anxiety disorders","volume":"21","author":"Otowa","year":"2016","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jad.2024.09.132_bb0285","article-title":"Association between thyroid dysfunction, metabolic disturbances, and clinical symptoms in first-episode, untreated Chinese patients with major depressive disorder: undirected and Bayesian network analyses","volume":"14","author":"Peng","year":"2023","journal-title":"Front Endocrinol (Lausanne)."},{"issue":"3","key":"10.1016\/j.jad.2024.09.132_bb0290","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1093\/ije\/dyq151","article-title":"Power and instrument strength requirements for Mendelian randomization studies using multiple genetic variants","volume":"40","author":"Pierce","year":"2011","journal-title":"Int. J. Epidemiol."},{"key":"10.1016\/j.jad.2024.09.132_bb0295","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.bbi.2016.12.020","article-title":"Th17 cells correlate positively to the structural and functional integrity of the brain in bipolar depression and healthy controls","volume":"61","author":"Poletti","year":"2017","journal-title":"Brain Behav. Immun."},{"issue":"3","key":"10.1016\/j.jad.2024.09.132_bb0300","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1136\/eb-2016-102412","article-title":"Prevalence, impact and treatment of generalised anxiety disorder in bipolar disorder: a systematic review and meta-analysis","volume":"19","author":"Preti","year":"2016","journal-title":"Evid. Based Ment. Health"},{"issue":"6","key":"10.1016\/j.jad.2024.09.132_bb0305","doi-asserted-by":"crossref","DOI":"10.1016\/j.beem.2019.101367","article-title":"Hashimotos\u2019 thyroiditis: epidemiology, pathogenesis, clinic and therapy","volume":"33","author":"Ragusa","year":"2019","journal-title":"Best Pract. Res. Clin. Endocrinol. Metab."},{"issue":"1","key":"10.1016\/j.jad.2024.09.132_bb0310","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/BF02123678","article-title":"HLA antigens in schizophrenia, major depressive disorder, and schizoaffective disorder","volume":"172","author":"R\u00f6sler","year":"1983","journal-title":"Med. Microbiol. Immunol."},{"issue":"10","key":"10.1016\/j.jad.2024.09.132_bb0315","doi-asserted-by":"crossref","first-page":"4269","DOI":"10.1007\/s12035-020-01961-y","article-title":"The microbiota-gut-immune-glia (MGIG) Axis in major depression","volume":"57","author":"Rudzki","year":"2020","journal-title":"Mol. Neurobiol."},{"issue":"3","key":"10.1016\/j.jad.2024.09.132_bb0320","doi-asserted-by":"crossref","first-page":"305","DOI":"10.23736\/S0391-1977.17.02757-2","article-title":"Autoimmune endocrine diseases","volume":"43","author":"Ruggeri","year":"2018","journal-title":"Minerva Endocrinol."},{"key":"10.1016\/j.jad.2024.09.132_bb0325","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1016\/j.jad.2020.09.139","article-title":"Properties of common anxiety scales among patients with bipolar disorder","volume":"281","author":"Seon","year":"2021","journal-title":"J. Affect. Disord."},{"issue":"6","key":"10.1016\/j.jad.2024.09.132_bb0330","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1001\/jamapsychiatry.2018.0190","article-title":"Association of Depression and Anxiety Disorders with Autoimmune Thyroiditis: a systematic review and Meta-analysis","volume":"75","author":"Siegmann","year":"2018","journal-title":"JAMA Psychiatry"},{"issue":"1","key":"10.1016\/j.jad.2024.09.132_bb0335","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/ije\/dyg070","article-title":"\u2018Mendelian randomization\u2019: can genetic epidemiology contribute to understanding environmental determinants of disease?","volume":"32","author":"Smith","year":"2003","journal-title":"Int. J. Epidemiol."},{"issue":"2","key":"10.1016\/j.jad.2024.09.132_bb0340","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1089\/thy.2022.0304","article-title":"Exploring the genetic link between thyroid dysfunction and common psychiatric disorders: a specific hormonal or a general autoimmune comorbidity","volume":"33","author":"Soheili-Nezhad","year":"2023","journal-title":"Thyroid"},{"key":"10.1016\/j.jad.2024.09.132_bb0345","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.coi.2014.08.005","article-title":"Molecular mechanisms for contribution of MHC molecules to autoimmune diseases","volume":"31","author":"Sollid","year":"2014","journal-title":"Curr. Opin. Immunol."},{"issue":"2","key":"10.1016\/j.jad.2024.09.132_bb0350","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1001\/jama.291.2.228","article-title":"Subclinical thyroid disease: scientific review and guidelines for diagnosis and management","volume":"291","author":"Surks","year":"2004","journal-title":"Jama"},{"issue":"2","key":"10.1016\/j.jad.2024.09.132_bb0355","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.arr.2005.03.003","article-title":"The stress system in the human brain in depression and neurodegeneration","volume":"4","author":"Swaab","year":"2005","journal-title":"Ageing Res. Rev."},{"issue":"4","key":"10.1016\/j.jad.2024.09.132_bb0360","doi-asserted-by":"crossref","DOI":"10.1177\/03000605211004199","article-title":"Meta-analysis reveals significant association between FOXP3 polymorphisms and susceptibility to Graves\u2019 disease","volume":"49","author":"Tan","year":"2021","journal-title":"J. Int. Med. Res."},{"issue":"6","key":"10.1016\/j.jad.2024.09.132_bb0365","doi-asserted-by":"crossref","first-page":"886","DOI":"10.4103\/ijem.IJEM_265_17","article-title":"Hypothyroidism and depression: are cytokines the link?","volume":"21","author":"Tayde","year":"2017","journal-title":"Indian J Endocrinol Metab."},{"issue":"8","key":"10.1016\/j.jad.2024.09.132_bb0370","article-title":"Genetic polymorphism of PTPN22 in autoimmune diseases: a comprehensive review","volume":"58","author":"Tizaoui","year":"2022","journal-title":"Medicina (Kaunas)"},{"issue":"3","key":"10.1016\/j.jad.2024.09.132_bb0375","doi-asserted-by":"crossref","first-page":"353","DOI":"10.2174\/1570159X14666160606210811","article-title":"Depression and mania in bipolar disorder","volume":"15","author":"Tondo","year":"2017","journal-title":"Curr. Neuropharmacol."},{"issue":"3","key":"10.1016\/j.jad.2024.09.132_bb0380","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1080\/10673220500174833","article-title":"Manic-depressive illness: evolution in Kraepelin\u2019s textbook, 1883-1926","volume":"13","author":"Trede","year":"2005","journal-title":"Harv. Rev. Psychiatry"},{"key":"10.1016\/j.jad.2024.09.132_bb0385","article-title":"Selenium supplementation for Hashimoto\u2019s thyroiditis","volume":"2013(6):Cd010223","author":"van Zuuren","year":"2013","journal-title":"Cochrane Database Syst. Rev."},{"issue":"6","key":"10.1016\/j.jad.2024.09.132_bb0390","doi-asserted-by":"crossref","DOI":"10.3390\/cells12060918","article-title":"Molecular mechanisms in autoimmune thyroid disease","volume":"12","author":"Vargas-Uricoechea","year":"2023","journal-title":"Cells"},{"issue":"5","key":"10.1016\/j.jad.2024.09.132_bb0395","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1034\/j.1399-5618.2001.30504.x","article-title":"Clinical correlates of psychiatric comorbidity in bipolar I patients","volume":"3","author":"Vieta","year":"2001","journal-title":"Bipolar Disord."},{"issue":"2","key":"10.1016\/j.jad.2024.09.132_bb0400","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.biopsych.2006.08.041","article-title":"Is autoimmune thyroiditis part of the genetic vulnerability (or an endophenotype) for bipolar disorder?","volume":"62","author":"Vonk","year":"2007","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2024.09.132_bb0405","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/s12879-016-1346-0","article-title":"Association between human leukocyte antigen class II and pulmonary tuberculosis due to mycobacterium tuberculosis in Uganda","volume":"16","author":"Wamala","year":"2016","journal-title":"BMC Infect. Dis."},{"issue":"1","key":"10.1016\/j.jad.2024.09.132_bb0410","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-020-75776-1","article-title":"An individual participant data analysis of prospective cohort studies on the association between subclinical thyroid dysfunction and depressive symptoms","volume":"10","author":"Wildisen","year":"2020","journal-title":"Sci. Rep."},{"issue":"3","key":"10.1016\/j.jad.2024.09.132_bb0415","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1111\/j.1365-2265.2008.03352.x","article-title":"Thyroid function and the natural history of depression: findings from the Caerphilly prospective study (CaPS) and a meta-analysis","volume":"70","author":"Williams","year":"2009","journal-title":"Clin. Endocrinol."},{"key":"10.1016\/j.jad.2024.09.132_bb0420","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/3916395","article-title":"General and specific genetic polymorphism of cytokines-related gene in AITD","volume":"2017","author":"Xiaoheng","year":"2017","journal-title":"Mediat. Inflamm."}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032724016215?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032724016215?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T10:10:22Z","timestamp":1730887822000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165032724016215"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":84,"alternative-id":["S0165032724016215"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2024.09.132","relation":{},"ISSN":["0165-0327"],"issn-type":[{"value":"0165-0327","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association of anxiety disorder, depression, and bipolar disorder with autoimmune thyroiditis: A bidirectional two-sample mendelian randomized study","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2024.09.132","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}