{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T02:55:50Z","timestamp":1777949750124,"version":"3.51.4"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T00:00:00Z","timestamp":1742947200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004271","name":"University of Rome La Sapienza","doi-asserted-by":"publisher","award":["RM11916B88717775"],"award-info":[{"award-number":["RM11916B88717775"]}],"id":[{"id":"10.13039\/501100004271","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1016\/j.jad.2025.03.098","type":"journal-article","created":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T02:43:40Z","timestamp":1743043420000},"page":"375-383","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["In search for affect in painful touch"],"prefix":"10.1016","volume":"380","author":[{"given":"Gianluca","family":"Cruciani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pietro","family":"Zingaretti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio","family":"De Filippis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ludovica","family":"Zanini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Iosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vittorio","family":"Lingiardi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grazia Fernanda","family":"Spitoni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jad.2025.03.098_bb0005","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.gaitpost.2021.08.004","article-title":"Extraction of gait parameters from marker-free video recordings of Timed Up-and-Go tests: validity, inter-and intra-rater reliability","volume":"90","author":"\u00c5berg","year":"2021","journal-title":"Gait Posture"},{"key":"10.1016\/j.jad.2025.03.098_bb0010","doi-asserted-by":"crossref","first-page":"54","DOI":"10.3389\/fnbeh.2014.00054","article-title":"Touch perceptions across skin sites: differences between sensitivity, direction discrimination and pleasantness","volume":"8","author":"Ackerley","year":"2014","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.jad.2025.03.098_bb0015","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1016\/S0140-6736(21)00476-1","article-title":"Borderline personality disorder","volume":"398","author":"Bohus","year":"2021","journal-title":"Lancet"},{"key":"10.1016\/j.jad.2025.03.098_bb0020","doi-asserted-by":"crossref","DOI":"10.1523\/ENEURO.0504-22.2023","article-title":"A\u03b2-CT affective touch: touch pleasantness ratings for gentle stroking and deep pressure exhibit dependence on A-fibers","volume":"10","author":"Case","year":"2023","journal-title":"Eneuro"},{"key":"10.1016\/j.jad.2025.03.098_bb0025","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0243680","article-title":"Affective touch topography and body image","volume":"16","author":"Cazzato","year":"2021","journal-title":"PLoS One"},{"key":"10.1016\/j.jad.2025.03.098_bb0030","doi-asserted-by":"crossref","first-page":"449","DOI":"10.3389\/fpsyt.2020.00449","article-title":"Self-harming and sense of agency in patients with borderline personality disorder","volume":"11","author":"Colle","year":"2020","journal-title":"Front. Psych."},{"key":"10.1016\/j.jad.2025.03.098_bb0035","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.neuroscience.2020.03.030","article-title":"Individual variability of pleasantness ratings to stroking touch over different velocities","volume":"464","author":"Croy","year":"2021","journal-title":"Neuroscience"},{"key":"10.1016\/j.jad.2025.03.098_bb0040","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.psychres.2016.01.078","article-title":"The perception of affective touch in anorexia nervosa","volume":"239","author":"Crucianelli","year":"2016","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.jad.2025.03.098_bb0045","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.neuroscience.2020.09.013","article-title":"The anticipation and perception of affective touch in women with and recovered from anorexia nervosa","volume":"464","author":"Crucianelli","year":"2021","journal-title":"Neuroscience"},{"key":"10.1016\/j.jad.2025.03.098_bb0050","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.jad.2023.08.126","article-title":"The perception of pain, discriminative touch and affective touch in patients suffering from Borderline Personality Disorder","volume":"341","author":"Cruciani","year":"2023","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2025.03.098_bb0055","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.pscychresns.2018.08.007","article-title":"Abnormal brain processing of gentle touch in anorexia nervosa","volume":"281","author":"Davidovic","year":"2018","journal-title":"Psychiatry Res. Neuroimaging"},{"key":"10.1016\/j.jad.2025.03.098_bb0060","doi-asserted-by":"crossref","first-page":"1986","DOI":"10.3389\/fpsyg.2015.01986","article-title":"The neurobiology shaping affective touch: expectation, motivation, and meaning in the multisensory context","volume":"6","author":"Ellingsen","year":"2016","journal-title":"Front. Psychol."},{"key":"10.1016\/j.jad.2025.03.098_bb0065","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.neubiorev.2009.02.003","article-title":"Quantitative assessment of pleasant touch","volume":"34","author":"Essick","year":"2010","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.jad.2025.03.098_bb0070","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.cobeha.2021.08.008","article-title":"Affective regulation through touch: homeostatic and allostatic mechanisms","volume":"43","author":"Fotopoulou","year":"2022","journal-title":"Curr. Opin. Behav. Sci."},{"key":"10.1016\/j.jad.2025.03.098_bb0075","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.jad.2017.05.048","article-title":"Emotional blunting with antidepressant treatments: a survey among depressed patients","volume":"221","author":"Goodwin","year":"2017","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2025.03.098_bb0080","doi-asserted-by":"crossref","first-page":"R1380","DOI":"10.1016\/j.cub.2018.11.014","article-title":"Stroking modulates noxious-evoked brain activity in human infants","volume":"28","author":"Gursul","year":"2018","journal-title":"Curr. Biol."},{"issue":"1","key":"10.1016\/j.jad.2025.03.098_bb0085","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1111\/papt.12367","article-title":"The subjective effect of antipsychotic medication on trauma-related thoughts, emotions, and physical symptoms: a qualitative study with people who have experienced childhood trauma and psychosis","volume":"95","author":"Kamitsis","year":"2022","journal-title":"Psychol. Psychother. Theory Res. Pract."},{"key":"10.1016\/j.jad.2025.03.098_bb0090","doi-asserted-by":"crossref","DOI":"10.1098\/rstb.2016.0009","article-title":"Affective touch and attachment style modulate pain: a laser-evoked potentials study","volume":"371","author":"Krah\u00e9","year":"2016","journal-title":"Philos. Trans. R. Soc. B"},{"key":"10.1016\/j.jad.2025.03.098_bb0095","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-018-32865-6","article-title":"Sensitivity to CT-optimal, affective touch depends on adult attachment style","volume":"8","author":"Krah\u00e9","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jad.2025.03.098_bb0100","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.cobeha.2021.09.005","article-title":"Role of C-tactile fibers in pain modulation: animal and human perspectives","volume":"43","author":"Larsson","year":"2022","journal-title":"Curr. Opin. Behav. Sci."},{"key":"10.1016\/j.jad.2025.03.098_bb0105","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1001\/jama.2023.0589","article-title":"Borderline personality disorder: a review","volume":"329","author":"Leichsenring","year":"2023","journal-title":"JAMA"},{"key":"10.1016\/j.jad.2025.03.098_bb0110","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1002\/ejp.1018","article-title":"Slow brushing reduces heat pain in humans","volume":"21","author":"Liljencrantz","year":"2017","journal-title":"Eur. J. Pain"},{"key":"10.1016\/j.jad.2025.03.098_bb0115","series-title":"Cognitive-Behavioral Treatment of Borderline Personality Disorder","author":"Linehan","year":"1993"},{"key":"10.1016\/j.jad.2025.03.098_bb0120","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1139\/jpn.0716","article-title":"Neuroimaging and genetics of borderline personality disorder: a review","volume":"32","author":"Lis","year":"2007","journal-title":"J. Psychiatry Neurosci."},{"key":"10.1016\/j.jad.2025.03.098_bb0125","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s40479-021-00176-4","article-title":"Pleasant touch perception in borderline personality disorder and its relationship with disturbed body representation","volume":"9","author":"L\u00f6ffler","year":"2022","journal-title":"Bord. Personal. Disord. Emot. Dysregul."},{"key":"10.1016\/j.jad.2025.03.098_bb0130","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1038\/nn.2312","article-title":"Coding of pleasant touch by unmyelinated afferents in humans","volume":"12","author":"L\u00f6ken","year":"2009","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.jad.2025.03.098_bb0135","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.psychres.2005.04.009","article-title":"Elevated pain thresholds correlate with dissociation and aversive arousal in patients with borderline personality disorder","volume":"149","author":"Lud\u00e4scher","year":"2007","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.jad.2025.03.098_bb0140","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/j.neuron.2014.05.001","article-title":"Discriminative and affective touch: sensing and feeling","volume":"82","author":"McGlone","year":"2014","journal-title":"Neuron"},{"key":"10.1016\/j.jad.2025.03.098_bb0145","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1111\/jnp.12250","article-title":"Neural basis of affective touch and pain: a novel model suggests possible targets for pain amelioration","volume":"16","author":"Meijer","year":"2022","journal-title":"J. Neuropsychol."},{"key":"10.1016\/j.jad.2025.03.098_bb0150","doi-asserted-by":"crossref","first-page":"2626","DOI":"10.1038\/s41598-024-52354-3","article-title":"Spatial factors influencing the pain-ameliorating effect of CT-optimal touch: a comparative study for modulating temporal summation of second pain","volume":"14","author":"Meijer","year":"2024","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jad.2025.03.098_bb0155","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0298345","article-title":"CT-optimal touch and chronic pain experience in Parkinson\u2019s disease; an intervention study","volume":"19","author":"Meijer","year":"2024","journal-title":"PLoS One"},{"key":"10.1016\/j.jad.2025.03.098_bb0160","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1007\/s00221-009-2007-y","article-title":"The skin as a social organ","volume":"204","author":"Morrison","year":"2010","journal-title":"Exp. Brain Res."},{"key":"10.1016\/j.jad.2025.03.098_bb0165","doi-asserted-by":"crossref","first-page":"48","DOI":"10.2174\/157340009787315262","article-title":"Emotion regulation and pain in borderline personality disorder","volume":"5","author":"Niedtfeld","year":"2009","journal-title":"Curr. Psychiatr. Rev."},{"key":"10.1016\/j.jad.2025.03.098_bb0170","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.biopsych.2010.04.015","article-title":"Affect regulation and pain in borderline personality disorder: a possible link to the understanding of self-injury","volume":"68","author":"Niedtfeld","year":"2010","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2025.03.098_bb0175","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1113\/jphysiol.1990.sp018135","article-title":"Low-threshold mechanoreceptive and nociceptive units with unmyelinated (C) fibres in the human supraorbital nerve","volume":"426","author":"Nordin","year":"1990","journal-title":"J. Physiol."},{"key":"10.1016\/j.jad.2025.03.098_bb0180","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.neubiorev.2008.09.011","article-title":"The neurophysiology of unmyelinated tactile afferents","volume":"34","author":"Olausson","year":"2010","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.jad.2025.03.098_bb0185","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.jad.2022.08.066","article-title":"Emotional blunting with bupropion and serotonin reuptake inhibitors in three randomized controlled trials for acute major depressive disorder","volume":"318","author":"Peters","year":"2022","journal-title":"J. Affect. Disord."},{"issue":"3","key":"10.1016\/j.jad.2025.03.098_bb0190","doi-asserted-by":"crossref","first-page":"173","DOI":"10.2174\/1574886314666190301152734","article-title":"Positive and negative effects of antipsychotic medication: an international online survey of 832 recipients","volume":"14","author":"Read","year":"2019","journal-title":"Curr. Drug Saf."},{"key":"10.1016\/j.jad.2025.03.098_bb0195","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.copsyc.2020.12.007","article-title":"Self-harm in the context of borderline personality disorder","volume":"37","author":"Reichl","year":"2021","journal-title":"Curr. Opin. Psychol."},{"key":"10.1016\/j.jad.2025.03.098_bb0200","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.chb.2017.09.011","article-title":"Virtual intimacy: propensity for physical contact between avatars in an online virtual environment","volume":"78","author":"Sadowski","year":"2018","journal-title":"Comput. Hum. Behav."},{"key":"10.1016\/j.jad.2025.03.098_bb0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.neubiorev.2023.105236","article-title":"What are C-tactile afferents and how do they relate to \u201caffective touch\u201d?","volume":"151","author":"Schirmer","year":"2023","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.jad.2025.03.098_bb0210","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1159\/000435940","article-title":"Pain in borderline personality disorder","volume":"30","author":"Schmahl","year":"2015","journal-title":"Pain Psychiatr. Disord."},{"key":"10.1016\/j.jad.2025.03.098_bb0215","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.jpsychires.2005.08.011","article-title":"Neuroimaging in borderline personality disorder","volume":"40","author":"Schmahl","year":"2006","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.jad.2025.03.098_bb0220","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.pain.2004.04.035","article-title":"Differential nociceptive deficits in patients with borderline personality disorder and self-injurious behavior: laser-evoked potentials, spatial discrimination of noxious stimuli, and pain ratings","volume":"110","author":"Schmahl","year":"2004","journal-title":"Pain"},{"key":"10.1016\/j.jad.2025.03.098_bb0225","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.biopsych.2015.03.027","article-title":"Neural correlates of disturbed emotion processing in borderline personality disorder: a multimodal meta-analysis","volume":"79","author":"Schulze","year":"2016","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2025.03.098_bb0230","doi-asserted-by":"crossref","first-page":"395","DOI":"10.3390\/brainsci14040395","article-title":"Brain activation for social cognition and emotion processing tasks in borderline personality disorder: a meta-analysis of neuroimaging studies","volume":"14","author":"Schurz","year":"2024","journal-title":"Brain Sci."},{"key":"10.1016\/j.jad.2025.03.098_bb0235","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1097\/ANC.0b013e31826093ee","article-title":"Comforting touch in the very preterm hospitalized infant: an integrative review","volume":"12","author":"Smith","year":"2012","journal-title":"Adv. Neonatal Care"},{"key":"10.1016\/j.jad.2025.03.098_bb0240","doi-asserted-by":"crossref","first-page":"9658","DOI":"10.1038\/s41598-020-66606-5","article-title":"Disorganized attachment pattern affects the perception of affective touch","volume":"10","author":"Spitoni","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jad.2025.03.098_bb0245","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1007\/s00426-019-01253-8","article-title":"Defining pleasant touch stimuli: a systematic review and meta-analysis","volume":"85","author":"Taneja","year":"2021","journal-title":"Psychol. Res."},{"key":"10.1016\/j.jad.2025.03.098_bb0250","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1113\/jphysiol.1993.sp019837","article-title":"Organization of motor output in slow finger movements in man","volume":"469","author":"Vallbo","year":"1993","journal-title":"J. Physiol."},{"key":"10.1016\/j.jad.2025.03.098_bb0255","series-title":"Encyclopedia of Neuroscience","first-page":"741","article-title":"Pleasant touch","author":"Vallbo","year":"2009"},{"key":"10.1016\/j.jad.2025.03.098_bb0260","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.physbeh.2019.04.024","article-title":"Does touch matter? The impact of stroking versus non-stroking maternal touch on cardio-respiratory processes in mothers and infants","volume":"207","author":"Van Puyvelde","year":"2019","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.jad.2025.03.098_bb0265","first-page":"1121","article-title":"The social buffering of pain by affective touch: a laser-evoked potential study in romantic couples","volume":"13","author":"von Mohr","year":"2018","journal-title":"Soc. Cogn. Affect. Neurosci."},{"issue":"1","key":"10.1016\/j.jad.2025.03.098_bb2000","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1038\/s41398-020-00916-0","article-title":"Increased anticipatory brain response to pleasant touch in women remitted from bulimia nervosa","volume":"10","author":"Wierenga","year":"2020","journal-title":"Translational psychiatry"},{"key":"10.1016\/j.jad.2025.03.098_bb0270","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1113\/jphysiol.1939.sp003707","article-title":"Touch, pain and tickling: an electro-physiological investigation on cutaneous sensory nerves","volume":"95","author":"Zotterman","year":"1939","journal-title":"J. Physiol."}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016503272500446X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016503272500446X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T04:24:38Z","timestamp":1777868678000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016503272500446X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":55,"alternative-id":["S016503272500446X"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2025.03.098","relation":{},"ISSN":["0165-0327"],"issn-type":[{"value":"0165-0327","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"In search for affect in painful touch","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2025.03.098","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}