{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T22:27:37Z","timestamp":1763504857862,"version":"3.45.0"},"reference-count":70,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100020595","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["NSTC 114\\u20132221-E-007-023-MY3","NSTC 114\\u20132321-B-002-026"],"award-info":[{"award-number":["NSTC 114\\u20132221-E-007-023-MY3","NSTC 114\\u20132321-B-002-026"]}],"id":[{"id":"10.13039\/100020595","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.jad.2025.120465","type":"journal-article","created":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T15:56:39Z","timestamp":1760543799000},"page":"120465","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"PB","title":["Association of bipolar disorder with new-onset delirium among critically ill patients"],"prefix":"10.1016","volume":"393","author":[{"given":"Chang-Chih","family":"Tsou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong-Wei","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hung-Wen","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jad.2025.120465_bb0005","doi-asserted-by":"crossref","DOI":"10.3390\/jcm12165346","article-title":"Delirium and its association with short- and long-term health outcomes in medically admitted patients: a prospective study","volume":"12","author":"Al Huraizi","year":"2023","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.jad.2025.120465_bb0010","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.ebiom.2018.10.021","article-title":"Surgery, neuroinflammation and cognitive impairment","volume":"37","author":"Alam","year":"2018","journal-title":"EBioMedicine"},{"key":"10.1016\/j.jad.2025.120465_bb0015","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1080\/00273171.2011.568786","article-title":"An introduction to propensity score methods for reducing the effects of confounding in observational studies","volume":"46","author":"Austin","year":"2011","journal-title":"Multivar. Behav. Res."},{"key":"10.1016\/j.jad.2025.120465_bb0020","doi-asserted-by":"crossref","first-page":"e99","DOI":"10.4037\/ajcc2021599","article-title":"Factors influencing CAM-ICU documentation and inappropriate \u201cunable to assess\u201d responses","volume":"30","author":"Awan","year":"2021","journal-title":"Am. J. Crit. Care"},{"key":"10.1016\/j.jad.2025.120465_bb0025","doi-asserted-by":"crossref","first-page":"2016","DOI":"10.2174\/1570159X22666240130091235","article-title":"Glymphatic system and psychiatric disorders: a rapid comprehensive scoping review","volume":"22","author":"Barlattani","year":"2024","journal-title":"Curr. Neuropharmacol."},{"key":"10.1016\/j.jad.2025.120465_bb0030","doi-asserted-by":"crossref","DOI":"10.1186\/s40345-024-00346-7","article-title":"The influence of PER3 VNTR genotypes on the age of onset in a group of bipolar I disorder patients: an exploratory study","volume":"12","author":"Barlattani","year":"2024","journal-title":"Int. J. Bipolar Disord."},{"key":"10.1016\/j.jad.2025.120465_bb0035","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.psyneuen.2015.10.014","article-title":"The HPA axis in bipolar disorder: systematic review and meta-analysis","volume":"63","author":"Belvederi Murri","year":"2016","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.jad.2025.120465_bb0040","doi-asserted-by":"crossref","first-page":"674","DOI":"10.4306\/pi.2017.14.5.674","article-title":"Genetic association of the PERIOD3 (Per3) clock gene with bipolar disorder","volume":"14","author":"Brasil Rocha","year":"2017","journal-title":"Psychiatry Investig."},{"key":"10.1016\/j.jad.2025.120465_bb0045","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1007\/s00134-024-07388-6","article-title":"Systemic inflammation and delirium during critical illness","volume":"50","author":"Brummel","year":"2024","journal-title":"Intensive Care Med."},{"key":"10.1016\/j.jad.2025.120465_bb0050","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.jcrc.2017.08.003","article-title":"Delirium and exposure to psychoactive medications in critically ill adults: a multi-Centre observational study","volume":"42","author":"Burry","year":"2017","journal-title":"J. Crit. Care"},{"key":"10.1016\/j.jad.2025.120465_bb0055","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1056\/NEJMra1906193","article-title":"Bipolar Disorder","volume":"383","author":"Carvalho","year":"2020","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jad.2025.120465_bb0060","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/2110-5820-2-49","article-title":"Delirium in the ICU: an overview","volume":"2","author":"Cavallazzi","year":"2012","journal-title":"Ann. Intensive Care"},{"key":"10.1016\/j.jad.2025.120465_bb0065","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1001\/jamapsychiatry.2013.1394","article-title":"Comorbidities and mortality in bipolar disorder: a Swedish national cohort study","volume":"70","author":"Crump","year":"2013","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.jad.2025.120465_bb0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2024.110285","article-title":"Microglial activation and neuroinflammation in acute and chronic cognitive deficits in sepsis","volume":"267","author":"Denver","year":"2025","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.jad.2025.120465_bb0075","doi-asserted-by":"crossref","first-page":"e825","DOI":"10.1097\/CCM.0000000000003299","article-title":"Clinical practice guidelines for the prevention and Management of Pain, agitation\/sedation, delirium, immobility, and sleep disruption in adult patients in the ICU","volume":"46","author":"Devlin","year":"2018","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.jad.2025.120465_bb0080","doi-asserted-by":"crossref","first-page":"2703","DOI":"10.1001\/jama.286.21.2703","article-title":"Delirium in mechanically ventilated patients: validity and reliability of the confusion assessment method for the intensive care unit (CAM-ICU)","volume":"286","author":"Ely","year":"2001","journal-title":"Jama"},{"key":"10.1016\/j.jad.2025.120465_bb0085","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1002\/wps.20989","article-title":"DSM-5-TR: overview of what\u2019s new and what\u2019s changed","volume":"21","author":"First","year":"2022","journal-title":"World Psychiatry"},{"key":"10.1016\/j.jad.2025.120465_bb0090","doi-asserted-by":"crossref","first-page":"2231","DOI":"10.1097\/CCM.0000000000001952","article-title":"The impact of interventions to improve sleep on delirium in the ICU: a systematic review and research framework","volume":"44","author":"Flannery","year":"2016","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.jad.2025.120465_bb0095","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.jad.2015.02.032","article-title":"A meta-analysis investigating the prevalence and moderators of migraines among people with bipolar disorder","volume":"178","author":"Fornaro","year":"2015","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2025.120465_bb0100","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2023-079140","article-title":"Association between body mass index and delirium incidence in critically ill patients: a retrospective cohort study based on the MIMIC-IV database","volume":"14","author":"Fu","year":"2024","journal-title":"BMJ Open"},{"key":"10.1016\/j.jad.2025.120465_bb0105","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1017\/S0033291724002575","article-title":"Co-occurrence between mental disorders and physical diseases: a study of nationwide primary-care medical records","volume":"54","author":"Hanna","year":"2024","journal-title":"Psychol. Med."},{"key":"10.1016\/j.jad.2025.120465_bb0110","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1038\/s41380-018-0213-3","article-title":"The neuropathology of bipolar disorder: systematic review and meta-analysis","volume":"25","author":"Harrison","year":"2020","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jad.2025.120465_bb0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclinane.2024.111566","article-title":"Effectiveness of a delirium risk assessment and multidisciplinary care approach in reducing delirium incidence among surgical intensive care unit patients: a retrospective pre-post intervention study","volume":"98","author":"Hsiao","year":"2024","journal-title":"J. Clin. Anesth."},{"key":"10.1016\/j.jad.2025.120465_bb0120","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1186\/s12912-024-02121-6","article-title":"Delirium in psychiatric settings: risk factors and assessment tools in patients with psychiatric illness: a scoping review","volume":"23","author":"Huang","year":"2024","journal-title":"BMC Nurs."},{"key":"10.1016\/j.jad.2025.120465_bb0125","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/S0140-6736(13)60688-1","article-title":"Delirium in elderly people","volume":"383","author":"Inouye","year":"2014","journal-title":"Lancet"},{"key":"10.1016\/j.jad.2025.120465_bb0130","unstructured":"Johnson, A., Bulgarelli, L., Pollard, T., et al, MIMIC-IV. https:\/\/physionet.org\/content\/mimiciv\/3.1\/ (accessed October 17)."},{"key":"10.1016\/j.jad.2025.120465_bb0135","doi-asserted-by":"crossref","DOI":"10.1038\/s41597-023-02136-9","article-title":"MIMIC-IV, a freely accessible electronic health record dataset","volume":"10","author":"Johnson","year":"2023","journal-title":"Sci Data"},{"key":"10.1016\/j.jad.2025.120465_bb0140","article-title":"A retrospective examination of sleep disturbance across the course of bipolar disorder","volume":"4","author":"Kanady","year":"2015","journal-title":"J. Sleep Disord. Ther."},{"key":"10.1016\/j.jad.2025.120465_bb0145","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2024.19640","article-title":"In-hospital delirium and disability and cognitive impairment after COVID-19 hospitalization","volume":"7","author":"Kaushik","year":"2024","journal-title":"JAMA Netw. Open"},{"key":"10.1016\/j.jad.2025.120465_bb0150","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1097\/CCM.0000000000004139","article-title":"Biomarkers of delirium duration and delirium severity in the ICU","volume":"48","author":"Khan","year":"2020","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.jad.2025.120465_bb0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.physbeh.2020.113244","article-title":"Hair cortisol concentrations in mental disorders: a systematic review","volume":"229","author":"Koumantarou Malisiova","year":"2021","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.jad.2025.120465_bb0160","doi-asserted-by":"crossref","first-page":"228","DOI":"10.9758\/cpn.2022.20.2.228","article-title":"Neuromolecular etiology of bipolar disorder: possible therapeutic targets of mood stabilizers","volume":"20","author":"Lee","year":"2022","journal-title":"Clin Psychopharmacol Neurosci."},{"key":"10.1016\/j.jad.2025.120465_bb0165","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1177\/0193841X211020245","article-title":"Imputation of missing covariate data Prior to propensity score analysis: a tutorial and evaluation of the robustness of practical approaches","volume":"45","author":"Leite","year":"2021","journal-title":"Eval. Rev."},{"key":"10.1016\/j.jad.2025.120465_bb0170","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-022-21170-y","article-title":"Neuroinflammation and neuroprogression produced by oxidative stress in euthymic bipolar patients with different onset disease times","volume":"12","author":"Lima","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jad.2025.120465_bb0175","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1038\/s41380-021-01091-4","article-title":"A unified model of the pathophysiology of bipolar disorder","volume":"27","author":"Magioncalda","year":"2022","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jad.2025.120465_bb0180","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1016\/j.jagp.2013.09.005","article-title":"Neuropathogenesis of delirium: review of current etiologic theories and common pathways","volume":"21","author":"Maldonado","year":"2013","journal-title":"Am. J. Geriatr. Psychiatry"},{"key":"10.1016\/j.jad.2025.120465_bb0185","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1056\/NEJMcp1605501","article-title":"Delirium in Hospitalized Older Adults","volume":"377","author":"Marcantonio","year":"2017","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jad.2025.120465_bb0190","first-page":"32","article-title":"Inflammatory biomarkers, cognitive functioning, and brain imaging abnormalities in bipolar disorder: a systematic review","volume":"21","author":"Mario","year":"2024","journal-title":"Clin. Neuropsychiatry"},{"key":"10.1016\/j.jad.2025.120465_bb0195","doi-asserted-by":"crossref","first-page":"Itc49","DOI":"10.7326\/AITC202010060","article-title":"Delirium","volume":"173","author":"Mattison","year":"2020","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.jad.2025.120465_bb0200","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1016\/S0140-6736(20)31544-0","article-title":"Bipolar disorders","volume":"396","author":"McIntyre","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.jad.2025.120465_bb0205","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1001\/archgenpsychiatry.2011.12","article-title":"Prevalence and correlates of bipolar spectrum disorder in the world mental health survey initiative","volume":"68","author":"Merikangas","year":"2011","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.jad.2025.120465_bb0210","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1177\/0891988719834346","article-title":"Biomarker predictors of delirium in acutely ill patients: a systematic review","volume":"32","author":"Michels","year":"2019","journal-title":"J. Geriatr. Psychiatry Neurol."},{"key":"10.1016\/j.jad.2025.120465_bb0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2024.109234","article-title":"Longitudinal hair cortisol in bipolar disorder and a mechanism based on HPA dynamics","volume":"27","author":"Milo","year":"2024","journal-title":"iScience"},{"issue":"11","key":"10.1016\/j.jad.2025.120465_bb0220","article-title":"Confusion assessment method for the intensive care unit (CAM-ICU) for the diagnosis of delirium in adults in critical care settings","author":"Miranda","year":"2023","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.jad.2025.120465_bb0225","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1056\/NEJMoa1915784","article-title":"Association between mental disorders and subsequent medical conditions","volume":"382","author":"Momen","year":"2020","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jad.2025.120465_bb0230","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.smrv.2014.06.006","article-title":"Sleep-wake disturbance in interepisode bipolar disorder and high-risk individuals: a systematic review and meta-analysis","volume":"20","author":"Ng","year":"2015","journal-title":"Sleep Med. Rev."},{"key":"10.1016\/j.jad.2025.120465_bb0235","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1001\/jama.2023.18588","article-title":"Diagnosis and treatment of bipolar disorder: a review","volume":"330","author":"Nierenberg","year":"2023","journal-title":"Jama"},{"key":"10.1016\/j.jad.2025.120465_bb0240","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2022.49950","article-title":"Predisposing and precipitating factors associated with delirium: a systematic review","volume":"6","author":"Ormseth","year":"2023","journal-title":"JAMA Netw. Open"},{"key":"10.1016\/j.jad.2025.120465_bb0245","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1056\/NEJMoa1301372","article-title":"Long-term cognitive impairment after critical illness","volume":"369","author":"Pandharipande","year":"2013","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jad.2025.120465_bb0250","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1586\/14737175.2013.811981","article-title":"Neurotrophins, inflammation and oxidative stress as illness activity biomarkers in bipolar disorder","volume":"13","author":"Pfaffenseller","year":"2013","journal-title":"Expert. Rev. Neurother."},{"key":"10.1016\/j.jad.2025.120465_bb0255","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1016\/j.chest.2019.12.003","article-title":"Sleep and delirium in adults who are critically ill: a contemporary review","volume":"157","author":"Pisani","year":"2020","journal-title":"Chest"},{"key":"10.1016\/j.jad.2025.120465_bb0260","doi-asserted-by":"crossref","DOI":"10.1038\/s41398-024-02921-z","article-title":"Inflammatory mediators in major depression and bipolar disorder","volume":"14","author":"Poletti","year":"2024","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.jad.2025.120465_bb0265","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/6219678","article-title":"Incidence and risk factors of delirium in the intensive care unit: a prospective cohort","volume":"2021","author":"Rahimi-Bashar","year":"2021","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.jad.2025.120465_bb0270","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2023.27750","article-title":"Trends in delirium and new antipsychotic and benzodiazepine use among hospitalized older adults before and after the onset of the COVID-19 pandemic","volume":"6","author":"Reppas-Rindlisbacher","year":"2023","journal-title":"JAMA Netw. Open"},{"key":"10.1016\/j.jad.2025.120465_bb0275","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.jad.2023.06.026","article-title":"Neuropsychological instruments for bipolar disorders: a systematic review on psychometric properties","volume":"338","author":"Rossetti","year":"2023","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2025.120465_bb0280","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1111\/j.1532-5415.2010.02762.x","article-title":"Delirium: an independent predictor of functional decline after cardiac surgery","volume":"58","author":"Rudolph","year":"2010","journal-title":"J. Am. Geriatr. Soc."},{"key":"10.1016\/j.jad.2025.120465_bb0285","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1038\/s41380-022-01924-w","article-title":"Inflammation and cognition in severe mental illness: patterns of covariation and subgroups","volume":"28","author":"S\u00e6ther","year":"2023","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jad.2025.120465_bb0290","doi-asserted-by":"crossref","first-page":"R210","DOI":"10.1186\/cc9333","article-title":"Delirium epidemiology in critical care (DECCA): an international study","volume":"14","author":"Salluh","year":"2010","journal-title":"Crit. Care"},{"key":"10.1016\/j.jad.2025.120465_bb0295","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1007\/s00134-021-06503-1","article-title":"Delirium in critical illness: clinical manifestations, outcomes, and management","volume":"47","author":"Stollings","year":"2021","journal-title":"Intensive Care Med."},{"key":"10.1016\/j.jad.2025.120465_bb0300","doi-asserted-by":"crossref","DOI":"10.1016\/j.iccn.2021.103108","article-title":"Factors contributing to poor sleep in critically ill patients: a systematic review and meta-synthesis of qualitative studies","volume":"67","author":"Sundstr\u00f8m","year":"2021","journal-title":"Intensive Crit. Care Nurs."},{"key":"10.1016\/j.jad.2025.120465_bb0305","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1080\/14787210.2020.1812384","article-title":"Sepsis-associated encephalopathy and septic encephalitis: an update","volume":"19","author":"Tauber","year":"2021","journal-title":"Expert Rev. Anti-Infect. Ther."},{"key":"10.1016\/j.jad.2025.120465_bb0310","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2022.104284","article-title":"The hypothalamus-pituitary-adrenal axis in sepsis- and hyperinflammation-induced critical illness: gaps in current knowledge and future translational research directions","volume":"84","author":"Van den Berghe","year":"2022","journal-title":"EBioMedicine"},{"key":"10.1016\/j.jad.2025.120465_bb0315","doi-asserted-by":"crossref","first-page":"R16","DOI":"10.1186\/cc6790","article-title":"A comparison of the CAM-ICU and the NEECHAM confusion scale in intensive care delirium assessment: an observational study in non-intubated patients","volume":"12","author":"Van Rompaey","year":"2008","journal-title":"Crit. Care"},{"key":"10.1016\/j.jad.2025.120465_bb0320","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.bpa.2012.07.003","article-title":"Epidemiology and risk factors for delirium across hospital settings","volume":"26","author":"Vasilevskis","year":"2012","journal-title":"Best Pract. Res. Clin. Anaesthesiol."},{"key":"10.1016\/j.jad.2025.120465_bb0325","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1007\/s00134-012-2494-3","article-title":"Circadian rhythm disruption in severe sepsis: the effect of ambient light on urinary 6-sulfatoxymelatonin secretion","volume":"38","author":"Verceles","year":"2012","journal-title":"Intensive Care Med."},{"key":"10.1016\/j.jad.2025.120465_bb0330","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.jad.2023.10.156","article-title":"Systemic inflammation and oxidative stress markers in patients with unipolar and bipolar depression: a large-scale study","volume":"346","author":"Wei","year":"2024","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2025.120465_bb0335","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/s41999-019-00276-z","article-title":"Distress in delirium: causes, assessment and management","volume":"11","author":"Williams","year":"2020","journal-title":"Eur Geriatr Med."},{"key":"10.1016\/j.jad.2025.120465_bb0340","article-title":"Delirium","volume":"6","author":"Wilson","year":"2020","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.jad.2025.120465_bb0345","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1001\/jama.2010.1013","article-title":"Delirium in elderly patients and the risk of postdischarge mortality, institutionalization, and dementia: a meta-analysis","volume":"304","author":"Witlox","year":"2010","journal-title":"JAMA"},{"key":"10.1016\/j.jad.2025.120465_bb0350","article-title":"Glymphatic dysfunction: a bridge between sleep disturbance and mood disorders","volume":"12","author":"Yan","year":"2021","journal-title":"Front. Psychol."}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016503272501907X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016503272501907X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T22:23:05Z","timestamp":1763504585000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016503272501907X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":70,"alternative-id":["S016503272501907X"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2025.120465","relation":{},"ISSN":["0165-0327"],"issn-type":[{"type":"print","value":"0165-0327"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association of bipolar disorder with new-onset delirium among critically ill patients","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2025.120465","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"120465"}}