{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T20:21:37Z","timestamp":1790713297478,"version":"4.1.0"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100005792","name":"University System of Taiwan","doi-asserted-by":"publisher","award":["VGHUST112-G1-8-1"],"award-info":[{"award-number":["VGHUST112-G1-8-1"]}],"id":[{"id":"10.13039\/501100005792","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005792","name":"University System of Taiwan","doi-asserted-by":"publisher","award":["VGHUST114-G1-9-1"],"award-info":[{"award-number":["VGHUST114-G1-9-1"]}],"id":[{"id":"10.13039\/501100005792","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001869","name":"Academia Sinica","doi-asserted-by":"publisher","award":["VTA114-V1-4-1"],"award-info":[{"award-number":["VTA114-V1-4-1"]}],"id":[{"id":"10.13039\/501100001869","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001869","name":"Academia Sinica","doi-asserted-by":"publisher","award":["VTA112-V1-6-1"],"award-info":[{"award-number":["VTA112-V1-6-1"]}],"id":[{"id":"10.13039\/501100001869","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010425","name":"Tri-Service General Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010425","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000779","name":"University of London","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000779","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006477","name":"National Taiwan University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006477","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011913","name":"Kaohsiung Veterans General Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011913","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011912","name":"Taipei Veterans General Hospital","doi-asserted-by":"publisher","award":["V114C-089"],"award-info":[{"award-number":["V114C-089"]}],"id":[{"id":"10.13039\/501100011912","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011912","name":"Taipei Veterans General Hospital","doi-asserted-by":"publisher","award":["V114C-064"],"award-info":[{"award-number":["V114C-064"]}],"id":[{"id":"10.13039\/501100011912","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011912","name":"Taipei Veterans General Hospital","doi-asserted-by":"publisher","award":["V113C-011"],"award-info":[{"award-number":["V113C-011"]}],"id":[{"id":"10.13039\/501100011912","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011912","name":"Taipei Veterans General Hospital","doi-asserted-by":"publisher","award":["V113C-039"],"award-info":[{"award-number":["V113C-039"]}],"id":[{"id":"10.13039\/501100011912","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011912","name":"Taipei Veterans General Hospital","doi-asserted-by":"publisher","award":["V113C-010"],"award-info":[{"award-number":["V113C-010"]}],"id":[{"id":"10.13039\/501100011912","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011912","name":"Taipei Veterans General Hospital","doi-asserted-by":"publisher","award":["V114C-217"],"award-info":[{"award-number":["V114C-217"]}],"id":[{"id":"10.13039\/501100011912","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["MOST111-2314-B-075-014-MY2"],"award-info":[{"award-number":["MOST111-2314-B-075-014-MY2"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["NSTC114-2314-B-075-022"],"award-info":[{"award-number":["NSTC114-2314-B-075-022"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["NSTC113-2314-B-075-042"],"award-info":[{"award-number":["NSTC113-2314-B-075-042"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["NSTC114-2314-B-075-023"],"award-info":[{"award-number":["NSTC114-2314-B-075-023"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["MOST111-2314-B-075-013"],"award-info":[{"award-number":["MOST111-2314-B-075-013"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["NSTC114-2628-B-A49-008-MY3"],"award-info":[{"award-number":["NSTC114-2628-B-A49-008-MY3"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007354","name":"Yen Tjing Ling Medical Foundation","doi-asserted-by":"publisher","award":["CI-113-32"],"award-info":[{"award-number":["CI-113-32"]}],"id":[{"id":"10.13039\/501100007354","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007354","name":"Yen Tjing Ling Medical Foundation","doi-asserted-by":"publisher","award":["CI-114-35"],"award-info":[{"award-number":["CI-114-35"]}],"id":[{"id":"10.13039\/501100007354","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007354","name":"Yen Tjing Ling Medical Foundation","doi-asserted-by":"publisher","award":["CI-113-30"],"award-info":[{"award-number":["CI-113-30"]}],"id":[{"id":"10.13039\/501100007354","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.jad.2025.120491","type":"journal-article","created":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T14:18:54Z","timestamp":1760797134000},"page":"120491","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"PA","title":["Default mode network and reward network dysconnectivity among young individuals with major depressive disorder with and without systemic low-grade inflammation"],"prefix":"10.1016","volume":"394","author":[{"given":"Ya-Mei","family":"Bai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Kai","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Chen","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ju-Wei","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Fen","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei-Chi","family":"Tu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng-Ta","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih-Jen","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Chi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tung-Ping","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mu-Hong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jad.2025.120491_bb0005","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2019.00458","article-title":"Low-grade inflammation as a predictor of antidepressant and anti-inflammatory therapy response in MDD patients: a systematic review of the literature in combination with an analysis of experimental data collected in the EU-MOODINFLAME Consortium","volume":"10","author":"Arteaga-Henriquez","year":"2019","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.jad.2025.120491_bb0010","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.bbi.2021.08.226","article-title":"Dysconnectivity of a brain functional network was associated with blood inflammatory markers in depression","volume":"98","author":"Aruldass","year":"2021","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.jad.2025.120491_bb0015","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.neuroimage.2007.07.007","article-title":"A fast diffeomorphic image registration algorithm","volume":"38","author":"Ashburner","year":"2007","journal-title":"NeuroImage"},{"key":"10.1016\/j.jad.2025.120491_bb0020","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/j.neuroimage.2005.02.018","article-title":"Unified segmentation","volume":"26","author":"Ashburner","year":"2005","journal-title":"NeuroImage"},{"key":"10.1016\/j.jad.2025.120491_bb0025","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/s12974-020-1724-9","article-title":"A comparison study of metabolic profiles, immunity, and brain gray matter volumes between patients with bipolar disorder and depressive disorder","volume":"17","author":"Bai","year":"2020","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.jad.2025.120491_bb0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.pscychresns.2022.111440","article-title":"C-reactive protein is related to a distinct set of alterations in resting-state functional connectivity contributing to a differential pathophysiology of major depressive disorder","volume":"321","author":"Beckmann","year":"2022","journal-title":"Psychiatry Res. Neuroimaging"},{"key":"10.1016\/j.jad.2025.120491_bb0035","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.3324\/haematol.2016.144055","article-title":"A score of low-grade inflammation and risk of mortality: prospective findings from the Moli-sani study","volume":"101","author":"Bonaccio","year":"2016","journal-title":"Haematologica"},{"key":"10.1016\/j.jad.2025.120491_bb0040","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.bbi.2021.01.016","article-title":"Elevated peripheral inflammation is associated with attenuated striatal reward anticipation in major depressive disorder","volume":"93","author":"Burrows","year":"2021","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.jad.2025.120491_bb0045","doi-asserted-by":"crossref","first-page":"5331","DOI":"10.1002\/hbm.23737","article-title":"The impact of T1 versus EPI spatial normalization templates for fMRI data analyses","volume":"38","author":"Calhoun","year":"2017","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.jad.2025.120491_bb0050","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/j.bbi.2020.07.004","article-title":"Inflammation is associated with decreased functional connectivity of insula in unmedicated bipolar disorder","volume":"89","author":"Chen","year":"2020","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.jad.2025.120491_bb0055","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1037\/amp0001218","article-title":"Increased functional connectivity between the midbrain and frontal cortex following bright light therapy in subthreshold depression: a randomized clinical trial","volume":"79","author":"Chen","year":"2024","journal-title":"Am. Psychol."},{"key":"10.1016\/j.jad.2025.120491_bb0060","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.molmet.2018.01.018","article-title":"Nucleus accumbens inflammation mediates anxiodepressive behavior and compulsive sucrose seeking elicited by saturated dietary fat","volume":"10","author":"Decarie-Spain","year":"2018","journal-title":"Mol. Metab."},{"key":"10.1016\/j.jad.2025.120491_bb0065","doi-asserted-by":"crossref","first-page":"311","DOI":"10.9740\/mhc.2021.11.311","article-title":"Clinical pearls for the monitoring and treatment of antipsychotic induced metabolic syndrome","volume":"11","author":"DeJongh","year":"2021","journal-title":"Ment. Health Clin."},{"key":"10.1016\/j.jad.2025.120491_bb0070","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.jad.2010.09.032","article-title":"Brain effects of antidepressants in major depression: a meta-analysis of emotional processing studies","volume":"130","author":"Delaveau","year":"2011","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2025.120491_bb0075","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.pnpbp.2017.03.016","article-title":"The anti-inflammatory mechanism of antidepressants - SSRIs, SNRIs","volume":"80","author":"Galecki","year":"2018","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.jad.2025.120491_bb0080","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2022.883927","article-title":"Immune-inflammatory biomarkers predict cognition and social functioning in patients with type 2 diabetes mellitus, major depressive disorder, bipolar disorder, and schizophrenia: a 1-year follow-up study","volume":"13","author":"Gares-Caballer","year":"2022","journal-title":"Front. Neurol."},{"key":"10.1016\/j.jad.2025.120491_bb0085","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyg.2023.1264221","article-title":"Connectome-based modeling reveals a resting-state functional network that mediates the relationship between social rejection and rumination","volume":"14","author":"Geng","year":"2023","journal-title":"Front. Psychol."},{"key":"10.1016\/j.jad.2025.120491_bb0090","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.biopsych.2014.09.002","article-title":"Emotion-dependent functional connectivity of the default mode network in adolescent depression","volume":"78","author":"Ho","year":"2015","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2025.120491_bb0095","doi-asserted-by":"crossref","DOI":"10.4088\/JCP.17m11540","article-title":"Repeated low-grade infections predict antidepressant-resistant depression: a nationwide population-based cohort study","volume":"79","author":"Jeng","year":"2018","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.jad.2025.120491_bb0100","doi-asserted-by":"crossref","first-page":"7346","DOI":"10.1038\/s41380-021-01272-1","article-title":"Peripheral inflammation is associated with micro-structural and functional connectivity changes in depression-related brain networks","volume":"26","author":"Kitzbichler","year":"2021","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jad.2025.120491_bb0105","article-title":"Correlates of C-reactive protein with neural reward circuitry in adolescents with psychiatric symptoms","volume":"9","author":"Liu","year":"2020","journal-title":"Brain Behav. Immun. Health"},{"key":"10.1016\/j.jad.2025.120491_bb0110","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1016\/j.bbi.2020.01.023","article-title":"To exclude or not to exclude: considerations and recommendations for C-reactive protein values higher than 10 mg\/L","volume":"87","author":"Mac Giollabhui","year":"2020","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.jad.2025.120491_bb0115","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.bbi.2021.09.007","article-title":"Anterior insula morphology and vulnerability to psychopathology-related symptoms in response to acute inflammation","volume":"99","author":"Mansson","year":"2022","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.jad.2025.120491_bb0120","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.bbi.2017.01.013","article-title":"Systemic inflammation and resting state connectivity of the default mode network","volume":"62","author":"Marsland","year":"2017","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.jad.2025.120491_bb0125","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1176\/appi.neuropsych.15120422","article-title":"Conflict-related anterior cingulate functional connectivity is associated with past suicidal ideation and behavior in recent-onset psychotic major mood disorders","volume":"28","author":"Minzenberg","year":"2016","journal-title":"J. Neuropsychiatr. Clin. Neurosci."},{"key":"10.1016\/j.jad.2025.120491_bb0130","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.jpsychires.2024.03.001","article-title":"The relationship of neuropsychiatric symptoms with inflammatory markers in the hippocampus and cingulate cortex of bipolar disorder subjects: a post-mortem study","volume":"173","author":"Nascimento","year":"2024","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.jad.2025.120491_bb0135","series-title":"Handbook of functional connectivity Magnetic Resonance Imaging methods in CONN","author":"Nieto-Castanon","year":"2020"},{"key":"10.1016\/j.jad.2025.120491_bb0140","doi-asserted-by":"crossref","DOI":"10.1093\/braincomms\/fcac281","article-title":"Hyperconnectivity and altered interactions of a nucleus accumbens network in post-stroke depression","volume":"4","author":"Oestreich","year":"2022","journal-title":"Brain Commun."},{"key":"10.1016\/j.jad.2025.120491_bb0145","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.psyneuen.2018.02.031","article-title":"Prevalence and correlates of low-grade systemic inflammation in adult psychiatric inpatients: an electronic health record-based study","volume":"91","author":"Osimo","year":"2018","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.jad.2025.120491_bb0150","doi-asserted-by":"crossref","first-page":"1958","DOI":"10.1017\/S0033291719001454","article-title":"Prevalence of low-grade inflammation in depression: a systematic review and meta-analysis of CRP levels","volume":"49","author":"Osimo","year":"2019","journal-title":"Psychol. Med."},{"key":"10.1016\/j.jad.2025.120491_bb0155","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1001\/jamapsychiatry.2024.2193","article-title":"Trajectories of inflammation in youth and risk of mental and cardiometabolic disorders in adulthood","volume":"81","author":"Palmer","year":"2024","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.jad.2025.120491_bb0160","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1038\/npp.2015.342","article-title":"Increased default mode network connectivity in individuals at high familial risk for depression","volume":"41","author":"Posner","year":"2016","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.jad.2025.120491_bb0165","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/B978-0-444-52903-9.00007-8","article-title":"Anatomy and physiology of the afferent visual system","volume":"102","author":"Prasad","year":"2011","journal-title":"Handb. Clin. Neurol."},{"key":"10.1016\/j.jad.2025.120491_bb0170","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.bbi.2023.07.007","article-title":"Interleukin-10 enhances activity of ventral tegmental area dopamine neurons resulting in increased dopamine release","volume":"113","author":"Ronstrom","year":"2023","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.jad.2025.120491_bb0175","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1001\/jamapsychiatry.2014.1734","article-title":"Antipsychotic treatment and functional connectivity of the striatum in first-episode schizophrenia","volume":"72","author":"Sarpal","year":"2015","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.jad.2025.120491_bb0180","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1177\/1073858412440596","article-title":"The angular gyrus: multiple functions and multiple subdivisions","volume":"19","author":"Seghier","year":"2013","journal-title":"Neuroscientist"},{"key":"10.1016\/j.jad.2025.120491_bb0185","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.cortex.2009.11.008","article-title":"Evidence for topographic organization in the cerebellum of motor control versus cognitive and affective processing","volume":"46","author":"Stoodley","year":"2010","journal-title":"Cortex"},{"key":"10.1016\/j.jad.2025.120491_bb0190","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.bbi.2021.02.018","article-title":"Associations between peripheral inflammation and resting state functional connectivity in adolescents","volume":"95","author":"Swartz","year":"2021","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.jad.2025.120491_bb0195","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1097\/HRP.0000000000000326","article-title":"Brick by brick: building a transdiagnostic understanding of inflammation in psychiatry","volume":"30","author":"Thylur","year":"2022","journal-title":"Harv. Rev. Psychiatry"},{"key":"10.1016\/j.jad.2025.120491_bb0200","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1093\/scan\/nsaa124","article-title":"The posterior crus II cerebellum is specialized for social mentalizing and emotional self-experiences: a meta-analysis","volume":"15","author":"Van Overwalle","year":"2020","journal-title":"Soc. Cogn. Affect. Neurosci."},{"key":"10.1016\/j.jad.2025.120491_bb0205","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1186\/s12974-022-02684-8","article-title":"Progranulin from different gliocytes in the nucleus accumbens exerts distinct roles in FTD- and neuroinflammation-induced depression-like behaviors","volume":"19","author":"Wang","year":"2022","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.jad.2025.120491_bb0210","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1089\/brain.2012.0073","article-title":"Conn: a functional connectivity toolbox for correlated and anticorrelated brain networks","volume":"2","author":"Whitfield-Gabrieli","year":"2012","journal-title":"Brain Connect."},{"key":"10.1016\/j.jad.2025.120491_bb0215","series-title":"Artifact Detection Tools (ART). Cambridge, MA Release Version","first-page":"11","volume":"vol. 7","author":"Whitfield-Gabrieli","year":"2011"},{"key":"10.1016\/j.jad.2025.120491_bb0220","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1002\/(SICI)1097-0193(1996)4:1<58::AID-HBM4>3.0.CO;2-O","article-title":"A unified statistical approach for determining significant signals in images of cerebral activation","volume":"4","author":"Worsley","year":"1996","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.jad.2025.120491_bb0225","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1007\/s12264-023-01052-7","article-title":"A comprehensive overview of the role of visual cortex malfunction in depressive disorders: opportunities and challenges","volume":"39","author":"Wu","year":"2023","journal-title":"Neurosci. Bull."},{"key":"10.1016\/j.jad.2025.120491_bb0230","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1017\/S1092852922000876","article-title":"Functional dysconnectivity of cerebellum and attention networks in emotional dysregulation shared between attention deficit hyperactivity disorder and major depressive disorder: a multimodal imaging study","volume":"28","author":"Wu","year":"2023","journal-title":"CNS Spectr."},{"issue":"2923\u20132938","key":"10.1016\/j.jad.2025.120491_bb0235","article-title":"Microglia-triggered plasticity of intrinsic excitability modulates psychomotor behaviors in acute cerebellar inflammation","volume":"28","author":"Yamamoto","year":"2019","journal-title":"Cell Rep."},{"key":"10.1016\/j.jad.2025.120491_bb0240","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.bbi.2019.05.011","article-title":"Inflammation and decreased functional connectivity in a widely-distributed network in depression: centralized effects in the ventral medial prefrontal cortex","volume":"80","author":"Yin","year":"2019","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.jad.2025.120491_bb0245","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1038\/s41386-023-01708-y","article-title":"Early life stress moderates the relation between systemic inflammation and neural activation to reward in adolescents both cross-sectionally and longitudinally","volume":"49","author":"Yuan","year":"2024","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.jad.2025.120491_bb0250","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2019.116287","article-title":"Rumination and the default mode network: meta-analysis of brain imaging studies and implications for depression","volume":"206","author":"Zhou","year":"2020","journal-title":"Neuroimage"}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032725019330?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032725019330?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T08:55:05Z","timestamp":1780822505000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165032725019330"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":50,"alternative-id":["S0165032725019330"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2025.120491","relation":{},"ISSN":["0165-0327"],"issn-type":[{"value":"0165-0327","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Default mode network and reward network dysconnectivity among young individuals with major depressive disorder with and without systemic low-grade inflammation","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2025.120491","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"120491"}}