{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T04:43:20Z","timestamp":1776573800803,"version":"3.51.2"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100009019","name":"Shenzhen University","doi-asserted-by":"publisher","award":["2024YG008"],"award-info":[{"award-number":["2024YG008"]}],"id":[{"id":"10.13039\/501100009019","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2024A1515013203"],"award-info":[{"award-number":["2024A1515013203"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2022A1515012503"],"award-info":[{"award-number":["2022A1515012503"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003785","name":"Guangdong Medical Research Foundation","doi-asserted-by":"publisher","award":["A2025094"],"award-info":[{"award-number":["A2025094"]}],"id":[{"id":"10.13039\/501100003785","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017610","name":"Shenzhen Science and Technology Innovation Program","doi-asserted-by":"publisher","award":["JCYJ20240813114616022"],"award-info":[{"award-number":["JCYJ20240813114616022"]}],"id":[{"id":"10.13039\/501100017610","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017610","name":"Shenzhen Science and Technology Innovation Program","doi-asserted-by":"publisher","award":["JCYJ20230807115916035"],"award-info":[{"award-number":["JCYJ20230807115916035"]}],"id":[{"id":"10.13039\/501100017610","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017610","name":"Shenzhen Science and Technology Innovation Program","doi-asserted-by":"publisher","award":["JCYJ20240813112900002"],"award-info":[{"award-number":["JCYJ20240813112900002"]}],"id":[{"id":"10.13039\/501100017610","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.jad.2025.121051","type":"journal-article","created":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T07:39:29Z","timestamp":1767080369000},"page":"121051","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Cortical microstructural alterations in first-episode and recurrent depression and their associations with gene expression profiles"],"prefix":"10.1016","volume":"399","author":[{"given":"Qianyun","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaojing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shengli","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziyun","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiwei","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongyan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingli","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gangqiang","family":"Hou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingwei","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jad.2025.121051_bb0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.neubiorev.2022.104922","article-title":"Association between Diffusion Tensor Imaging, inflammation and immunological alterations in unipolar and bipolar depression: a review","volume":"143","author":"Aronica","year":"2022","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.jad.2025.121051_bb0010","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1038\/sj.mp.4001565","article-title":"Transcriptional profiling reveals evidence for signaling and oligodendroglial abnormalities in the temporal cortex from patients with major depressive disorder","volume":"10","author":"Aston","year":"2005","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jad.2025.121051_bb0015","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1002\/sim.6004","article-title":"A comparison of 12 algorithms for matching on the propensity score","volume":"33","author":"Austin","year":"2014","journal-title":"Stat. Med."},{"key":"10.1016\/j.jad.2025.121051_bb0020","doi-asserted-by":"crossref","first-page":"4690","DOI":"10.1002\/hbm.23694","article-title":"Comparison of two different analysis approaches for DTI free-water corrected and uncorrected maps in the study of white matter microstructural integrity in individuals with depression","volume":"38","author":"Bergamino","year":"2017","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.jad.2025.121051_bb0025","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1111\/epi.17204","article-title":"Structure and function of language networks in temporal lobe epilepsy","volume":"63","author":"Binding","year":"2022","journal-title":"Epilepsia"},{"key":"10.1016\/j.jad.2025.121051_bb0030","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/j.cpr.2007.02.005","article-title":"Risk for recurrence in depression","volume":"27","author":"Burcusa","year":"2007","journal-title":"Clin. Psychol. Rev."},{"key":"10.1016\/j.jad.2025.121051_bb0035","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1016\/j.neuroimage.2006.01.021","article-title":"An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest","volume":"31","author":"Desikan","year":"2006","journal-title":"NeuroImage"},{"key":"10.1016\/j.jad.2025.121051_bb0040","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.jad.2010.03.001","article-title":"Risk factors of treatment resistance in major depression: association with bipolarity","volume":"126","author":"Dudek","year":"2010","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2025.121051_bb0045","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/j.jad.2023.01.051","article-title":"Transcriptional substrates of brain structural and functional impairments in drug-naive first-episode patients with major depressive disorder","volume":"325","author":"Fang","year":"2023","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2025.121051_bb0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s43856-023-00324-7","article-title":"Cortical microstructural changes predict tau accumulation and episodic memory decline in older adults harboring amyloid","volume":"3","author":"Gagliardi","year":"2023","journal-title":"Commun. Med."},{"key":"10.1016\/j.jad.2025.121051_bb0055","doi-asserted-by":"crossref","DOI":"10.1126\/science.1252304","article-title":"Neuronal activity promotes oligodendrogenesis and adaptive myelination in the mammalian brain","volume":"344","author":"Gibson","year":"2014","journal-title":"Science"},{"key":"10.1016\/j.jad.2025.121051_bb0060","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.neuroimage.2009.06.060","article-title":"Accurate and robust brain image alignment using boundary-based registration","volume":"48","author":"Greve","year":"2009","journal-title":"NeuroImage"},{"key":"10.1016\/j.jad.2025.121051_bb0065","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1016\/j.neuron.2023.03.017","article-title":"Resolving the prefrontal mechanisms of adaptive cognitive behaviors: a cross-species perspective","volume":"111","author":"Hanganu-Opatz","year":"2023","journal-title":"Neuron"},{"key":"10.1016\/j.jad.2025.121051_bb0070","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1038\/nature11405","article-title":"An anatomically comprehensive atlas of the adult human brain transcriptome","volume":"489","author":"Hawrylycz","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.jad.2025.121051_bb0075","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.1038\/nn.4171","article-title":"Canonical genetic signatures of the adult human brain","volume":"18","author":"Hawrylycz","year":"2015","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.jad.2025.121051_bb0080","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-024-67535-3","article-title":"Microstructural brain assessment in late-life depression and apathy using diffusion MRI multi-compartments models and tractometry","volume":"14","author":"H\u00e9douin","year":"2024","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jad.2025.121051_bb0085","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1038\/s41593-018-0121-5","article-title":"Myelin remodeling through experience-dependent oligodendrogenesis in the adult somatosensory cortex","volume":"21","author":"Hughes","year":"2018","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.jad.2025.121051_bb0090","doi-asserted-by":"crossref","first-page":"e2565","DOI":"10.1212\/WNL.0000000000010727","article-title":"Cortical microstructure in the amyotrophic lateral sclerosis\u2013frontotemporal dementia continuum","volume":"95","author":"Ill\u00e1n-Gala","year":"2020","journal-title":"Neurology"},{"key":"10.1016\/j.jad.2025.121051_bb0095","series-title":"Fast Gene Set Enrichment Analysis","author":"Korotkevich","year":"2021"},{"key":"10.1016\/j.jad.2025.121051_bb0100","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1038\/nbt.4038","article-title":"Integrative single-cell analysis of transcriptional and epigenetic states in the human adult brain","volume":"36","author":"Lake","year":"2018","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.jad.2025.121051_bb0105","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1002\/mrm.21890","article-title":"The B-matrix must be rotated when correcting for subject motion in DTI data","volume":"61","author":"Leemans","year":"2009","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.jad.2025.121051_bb0110","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41398-022-02113-7","article-title":"Brain structural correlates of recurrence following the first episode in patients with major depressive disorder","volume":"12","author":"Lemke","year":"2022","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.jad.2025.121051_bb0115","first-page":"111","article-title":"Elevated extracellular free water in the brain predicts clinical improvement in first-episode psychosis","volume":"10","author":"Lesh","year":"2025","journal-title":"Biol. Psychiatry: Cognit. Neurosci. Neuroimaging"},{"key":"10.1016\/j.jad.2025.121051_bb0120","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1038\/s41386-019-0563-9","article-title":"Meta-analysis of cortical thickness abnormalities in medication-free patients with major depressive disorder","volume":"45","author":"Li","year":"2020","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.jad.2025.121051_bb0125","doi-asserted-by":"crossref","first-page":"283","DOI":"10.3390\/biom11020283","article-title":"Hormonal regulation of oligodendrogenesis I: effects across the lifespan","volume":"11","author":"Long","year":"2021","journal-title":"Biomolecules"},{"key":"10.1016\/j.jad.2025.121051_bb0130","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1176\/appi.ajp.2017.16111286","article-title":"Association of a history of child abuse with impaired myelination in the anterior cingulate cortex: convergent epigenetic, transcriptional, and morphological evidence","volume":"174","author":"Lutz","year":"2017","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.jad.2025.121051_bb0135","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.72129","article-title":"Standardizing workflows in imaging transcriptomics with the abagen toolbox","volume":"10","author":"Markello","year":"2021","journal-title":"eLife"},{"key":"10.1016\/j.jad.2025.121051_bb0140","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41572-023-00454-1","article-title":"Major depressive disorder","volume":"9","author":"Marx","year":"2023","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.jad.2025.121051_bb0145","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1037\/a0025190","article-title":"Recurrence in major depression: a conceptual analysis","volume":"118","author":"Monroe","year":"2011","journal-title":"Psychol. Rev."},{"key":"10.1016\/j.jad.2025.121051_bb0150","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.jalz.2017.09.013","article-title":"Cortical microstructural changes along the Alzheimer\u2019s disease continuum","volume":"14","author":"Montal","year":"2018","journal-title":"Alzheimers Dement."},{"key":"10.1016\/j.jad.2025.121051_bb0155","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1038\/mp.2016.130","article-title":"Whole-transcriptome brain expression and exon-usage profiling in major depression and suicide: evidence for altered glial, endothelial and ATPase activity","volume":"22","author":"Pantazatos","year":"2017","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jad.2025.121051_bb0160","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1002\/mds.29761","article-title":"Cortical macro- and microstructural changes in Parkinson\u2019s disease with probable rapid eye movement sleep behavior disorder","volume":"39","author":"Pardo","year":"2024","journal-title":"Mov. Disord."},{"key":"10.1016\/j.jad.2025.121051_bb0165","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1002\/mrm.22055","article-title":"Free water elimination and mapping from diffusion MRI","volume":"62","author":"Pasternak","year":"2009","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.jad.2025.121051_bb0170","first-page":"305","article-title":"Estimation of extracellular volume from regularized multi-shell diffusion MRI","volume":"15","author":"Pasternak","year":"2012","journal-title":"Med. Image Comput. Comput. Assist. Interv."},{"key":"10.1016\/j.jad.2025.121051_bb0175","doi-asserted-by":"crossref","DOI":"10.1016\/j.ynstr.2022.100451","article-title":"Effects of chronic social stress on oligodendrocyte proliferation-maturation and myelin status in prefrontal cortex and amygdala in adult mice","volume":"18","author":"Poggi","year":"2022","journal-title":"Neurobiol. Stress"},{"key":"10.1016\/j.jad.2025.121051_bb0180","doi-asserted-by":"crossref","first-page":"e378","DOI":"10.1038\/tp.2014.18","article-title":"Regional increases of cortical thickness in untreated, first-episode major depressive disorder","volume":"4","author":"Qiu","year":"2014","journal-title":"Transl. Psychiatry"},{"issue":"Suppl","key":"10.1016\/j.jad.2025.121051_bb0185","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1038\/ng1032","article-title":"Microarray data normalization and transformation","volume":"32","author":"Quackenbush","year":"2002","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jad.2025.121051_bb0190","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.comppsych.2010.04.011","article-title":"Clinical differences between first and recurrent episodes in depressive patients","volume":"52","author":"Roca","year":"2011","journal-title":"Compr. Psychiatry"},{"key":"10.1016\/j.jad.2025.121051_bb0195","doi-asserted-by":"crossref","first-page":"7813","DOI":"10.1038\/s41380-021-01290-z","article-title":"Association of cortical microstructure with amyloid-\u03b2 and tau: impact on cognitive decline, neurodegeneration, and clinical progression in older adults","volume":"26","author":"Rodriguez-Vieitez","year":"2021","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jad.2025.121051_bb0200","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1093\/brain\/awae054","article-title":"Cortical microstructural imaging from diffusion MRI: towards sensitive biomarkers for clinical trials","volume":"147","author":"Rodriguez-Vieitez","year":"2024","journal-title":"Brain"},{"key":"10.1016\/j.jad.2025.121051_bb0205","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.neuroimage.2017.12.060","article-title":"Structural covariance networks are coupled to expression of genes enriched in supragranular layers of the human cortex","volume":"171","author":"Romero-Garcia","year":"2018","journal-title":"NeuroImage"},{"key":"10.1016\/j.jad.2025.121051_bb0210","doi-asserted-by":"crossref","first-page":"2643","DOI":"10.1016\/j.neuroimage.2010.11.011","article-title":"Prefrontal cortical abnormalities in currently depressed versus currently remitted patients with major depressive disorder","volume":"54","author":"Salvadore","year":"2011","journal-title":"NeuroImage"},{"key":"10.1016\/j.jad.2025.121051_bb0215","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1038\/mp.2015.69","article-title":"Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group","volume":"21","author":"Schmaal","year":"2016","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jad.2025.121051_bb0220","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1038\/mp.2016.60","article-title":"Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group","volume":"22","author":"Schmaal","year":"2017","journal-title":"Mol. Psychiatry"},{"issue":"25","key":"10.1016\/j.jad.2025.121051_bb0225","article-title":"Structural connectome architecture shapes cortical atrophy in major depressive disorder: a Chinese DIRECT consortium study","volume":"S0006-3223","author":"Shen","year":"2025","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2025.121051_bb0230","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1093\/brain\/awad428","article-title":"Diffusion MRI tracks cortical microstructural changes during the early stages of Alzheimer\u2019s disease","volume":"147","author":"Spotorno","year":"2024","journal-title":"Brain"},{"key":"10.1016\/j.jad.2025.121051_bb0235","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.pnpbp.2018.08.008","article-title":"Cortical thickness in major depressive disorder: a systematic review and meta-analysis","volume":"88","author":"Suh","year":"2019","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.jad.2025.121051_bb0240","doi-asserted-by":"crossref","first-page":"6468","DOI":"10.1017\/S0033291722003750","article-title":"Cerebral blood flow changes and their genetic mechanisms in major depressive disorder: a combined neuroimaging and transcriptome study","volume":"53","author":"Sun","year":"2023","journal-title":"Psychol. Med."},{"key":"10.1016\/j.jad.2025.121051_bb0245","doi-asserted-by":"crossref","first-page":"7048","DOI":"10.1002\/alz.14176","article-title":"Spatial and temporal patterns of cortical mean diffusivity in Alzheimer\u2019s disease and suspected non-Alzheimer\u2019s disease pathophysiology","volume":"20","author":"Sun","year":"2024","journal-title":"Alzheimers Dement."},{"key":"10.1016\/j.jad.2025.121051_bb0250","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1111\/acps.13385","article-title":"Functional and cognitive impairment in the first episode of depression: a systematic review","volume":"145","author":"Varghese","year":"2022","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.jad.2025.121051_bb0255","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/s13195-015-0132-3","article-title":"Diffusion imaging changes in grey matter in Alzheimer\u2019s disease: a potential marker of early neurodegeneration","volume":"7","author":"Weston","year":"2015","journal-title":"Alzheimer\u2019s Res. Ther."},{"key":"10.1016\/j.jad.2025.121051_bb0260","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1038\/s41398-022-02147-x","article-title":"Identification of suicidality in patients with major depressive disorder via dynamic functional network connectivity signatures and machine learning","volume":"12","author":"Xu","year":"2022","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.jad.2025.121051_bb0265","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/j.neuroimage.2012.03.072","article-title":"NODDI: practical in vivo neurite orientation dispersion and density imaging of the human brain","volume":"61","author":"Zhang","year":"2012","journal-title":"NeuroImage"},{"key":"10.1016\/j.jad.2025.121051_bb0270","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1038\/s41467-019-09234-6","article-title":"Metascape provides a biologist-oriented resource for the analysis of systems-level datasets","volume":"10","author":"Zhou","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jad.2025.121051_bb0275","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1038\/s41380-020-00930-0","article-title":"Oligodendrocyte lineage cells and depression","volume":"26","author":"Zhou","year":"2021","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jad.2025.121051_bb0280","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1038\/s42003-024-06665-w","article-title":"Transcriptomic decoding of regional cortical vulnerability to major depressive disorder","volume":"7","author":"Zhu","year":"2024","journal-title":"Commun. Biol."}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032725024930?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032725024930?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T04:07:30Z","timestamp":1776571650000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165032725024930"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":56,"alternative-id":["S0165032725024930"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2025.121051","relation":{},"ISSN":["0165-0327"],"issn-type":[{"value":"0165-0327","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cortical microstructural alterations in first-episode and recurrent depression and their associations with gene expression profiles","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2025.121051","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"121051"}}