{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T09:01:56Z","timestamp":1777798916026,"version":"3.51.4"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T00:00:00Z","timestamp":1768780800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["GHS-15-0017"],"award-info":[{"award-number":["GHS-15-0017"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["GHS-23-0025"],"award-info":[{"award-number":["GHS-23-0025"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.jad.2026.121175","type":"journal-article","created":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T16:01:15Z","timestamp":1768060875000},"page":"121175","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Transcranial sonography of the brainstem raphe: A rapid tool to assess the long-term risk of violent suicidal behavior in patients with major depression"],"prefix":"10.1016","volume":"399","author":[{"given":"Uwe","family":"Walter","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lara","family":"Kaulitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Heilmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"\u0160koloud\u00edk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacqueline","family":"H\u00f6ppner-Buchmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jad.2026.121175_bb0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.neubiorev.2024.105594","article-title":"Risk of suicidal behavior in patients with major depression and bipolar disorder - a systematic review and meta-analysis of registry-based studies","volume":"159","author":"Arnone","year":"2024","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.jad.2026.121175_bb0010","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.biopsych.2020.06.002","article-title":"Neural correlates associated with suicide and nonsuicidal self-injury in youth","volume":"89","author":"Auerbach","year":"2021","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2026.121175_bb0015","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1002\/syn.21695","article-title":"Elevated serotonin and 5-HIAA in the brainstem and lower serotonin turnover in the prefrontal cortex of suicides","volume":"68","author":"Bach","year":"2014","journal-title":"Synapse"},{"key":"10.1016\/j.jad.2026.121175_bb0020","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1038\/sj.npp.1300897","article-title":"Neuronal tryptophan hydroxylase mRNA expression in the human dorsal and median raphe nuclei: major depression and suicide","volume":"31","author":"Bach-Mizrachi","year":"2006","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.jad.2026.121175_bb0025","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1038\/sj.mp.4002143","article-title":"Elevated expression of tryptophan hydroxylase-2 mRNA at the neuronal level in the dorsal and median raphe nuclei of depressed suicides","volume":"13","author":"Bach-Mizrachi","year":"2008","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jad.2026.121175_bb0030","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1016\/j.jad.2013.05.082","article-title":"Smoking and suicidality in subjects with major depressive disorder: results from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)","volume":"150","author":"Baek","year":"2013","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2026.121175_bb0035","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1001\/archpsyc.1961.01710120031004","article-title":"An inventory for measuring depression","volume":"4","author":"Beck","year":"1961","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.jad.2026.121175_bb0040","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/0925-4927(94)90002-7","article-title":"Echogenicity of the brainstem raphe in patients with major depression","volume":"55","author":"Becker","year":"1994","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.jad.2026.121175_bb0045","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/0006-3223(94)00263-3","article-title":"Reduced echogenicity of brainstem raphe specific to unipolar depression: a transcranial color-coded real-time sonography study","volume":"38","author":"Becker","year":"1995","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2026.121175_bb0050","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1017\/S1461145701002164","article-title":"Basal limbic system alteration in major depression: a hypothesis supported by transcranial sonography and MRI findings","volume":"4","author":"Becker","year":"2001","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.jad.2026.121175_bb0055","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1212\/WNL.53.5.1026","article-title":"Vulnerability of the nigrostriatal system as detected by transcranial ultrasound","volume":"53","author":"Berg","year":"1999","journal-title":"Neurology"},{"key":"10.1016\/j.jad.2026.121175_bb0060","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/S0006-3223(01)01190-8","article-title":"Echogenicity of substantia nigra determined by transcranial ultrasound correlates with severity of parkinsonian symptoms induced by neuroleptic therapy","volume":"50","author":"Berg","year":"2001","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2026.121175_bb0065","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.brainres.2005.01.083","article-title":"More tryptophan hydroxylase in the brainstem dorsal raphe nucleus in depressed suicides","volume":"1041","author":"Boldrini","year":"2005","journal-title":"Brain Res."},{"key":"10.1016\/j.jad.2026.121175_bb0070","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/s00406-009-0090-5","article-title":"Brainstem raphe lesion in patients with major depressive disorder and in patients with suicidal ideation recorded on transcranial sonography","volume":"260","author":"Budisic","year":"2010","journal-title":"Eur. Arch. Psychiatry Clin. Neurosci."},{"key":"10.1016\/j.jad.2026.121175_bb0075","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/j.biopsych.2024.09.010","article-title":"Recent breakthroughs in genetic and brain structural correlates of suicidal behaviors: a short review","volume":"97","author":"Ceja","year":"2025","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2026.121175_bb0080","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.biopsych.2003.07.004","article-title":"Serotonin transporter gene may be involved in short-term risk of subsequent suicide attempts","volume":"55","author":"Courtet","year":"2004","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2026.121175_bb0085","series-title":"Recent Developments in Parkinson\u2019s Disease II","first-page":"153","article-title":"Unified Parkinson\u2019s disease rating scale","author":"Fahn","year":"1987"},{"key":"10.1016\/j.jad.2026.121175_bb0090","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.pnpbp.2018.08.007","article-title":"The influence of the serotonin transporter gene 5-HTTLPR polymorphism on suicidal behaviors: a meta-analysis","volume":"88","author":"Fanelli","year":"2019","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.jad.2026.121175_bb0095","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1111\/acps.13620","article-title":"Meta-analysis of clinical risk factors for suicide among people presenting to emergency departments and general hospitals with suicidal thoughts and behaviours","volume":"148","author":"Grover","year":"2023","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.jad.2026.121175_bb0100","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1177\/0333102416665225","article-title":"Midbrain raphe hypoechogenicity in migraineurs: an indicator for the use of analgesics but not triptans","volume":"37","author":"Hamerla","year":"2017","journal-title":"Cephalalgia"},{"key":"10.1016\/j.jad.2026.121175_bb0105","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1111\/j.2044-8260.1967.tb00530.x","article-title":"Development of a rating scale for primary depressive illness","volume":"6","author":"Hamilton","year":"1967","journal-title":"Br. J. Soc. Clin. Psychol."},{"key":"10.1016\/j.jad.2026.121175_bb0110","series-title":"Suicidal Ideation","author":"Harmer","year":"2024"},{"key":"10.1016\/j.jad.2026.121175_bb0115","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.jpsychires.2021.01.045","article-title":"Cerebrospinal fluid levels of monoamines among suicide attempters: a systematic review and random-effects meta-analysis","volume":"136","author":"Hoertel","year":"2021","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.jad.2026.121175_bb0120","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.jchemneu.2003.10.002","article-title":"The human raphe nuclei and the serotonergic system","volume":"26","author":"Hornung","year":"2003","journal-title":"J. Chem. Neuroanat."},{"key":"10.1016\/j.jad.2026.121175_bb0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.jad.2025.119986","article-title":"Socioeconomic, demographic, and occupational risk factors for suicide amongst males: a systematic review and meta-analysis","volume":"391","author":"Hughes","year":"2025","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2026.121175_bb0130","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.psychres.2007.10.007","article-title":"CSF 5-HIAA and DST non-suppression\u2013orthogonal biologic risk factors for suicide in male mood disorder inpatients","volume":"165","author":"Jokinen","year":"2009","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.jad.2026.121175_bb0135","doi-asserted-by":"crossref","first-page":"428","DOI":"10.3390\/genes16040428","article-title":"Genetics of suicide","volume":"16","author":"Khalil","year":"2025","journal-title":"Genes (Basel)"},{"key":"10.1016\/j.jad.2026.121175_bb0140","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1016\/S0140-6736(22)00173-8","article-title":"Suicide and self-harm","volume":"399","author":"Knipe","year":"2022","journal-title":"Lancet"},{"key":"10.1016\/j.jad.2026.121175_bb0145","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.jad.2016.11.034","article-title":"A pilot study on predictors of brainstem raphe abnormality in patients with major depressive disorder","volume":"209","author":"Kosti\u0107","year":"2017","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2026.121175_bb0150","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1055\/a-2081-1635","article-title":"Echogenicity of brain structures in Huntington\u2019s disease patients evaluated by transcranial sonography - magnetic resonance fusion imaging using virtual navigator and digital image analysis","volume":"44","author":"Kozel","year":"2023","journal-title":"Ultraschall. Med."},{"key":"10.1016\/j.jad.2026.121175_bb0155","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/jon.12328","article-title":"Transcranial sonography findings in depression in association with psychiatric and neurologic diseases: a review","volume":"26","author":"Krogias","year":"2016","journal-title":"J. Neuroimaging"},{"key":"10.1016\/j.jad.2026.121175_bb5000","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.pscychresns.2011.04.002","article-title":"Evaluation of basal ganglia, brainstem raphe and ventricles in bipolar disorder by transcranial sonography","volume":"194","author":"Krogias","year":"2011","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.jad.2026.121175_bb0160","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1111\/jon.12038","article-title":"Brainstem raphe alterations depicted by transcranial sonography do not result in serotonergic functional impairment","volume":"23","author":"Krogias","year":"2013","journal-title":"J. Neuroimaging"},{"key":"10.1016\/j.jad.2026.121175_bb0165","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.1038\/s41386-023-01676-3","article-title":"Effect of selective serotonin reuptake inhibitor treatment following diagnosis of depression on suicidal behaviour risk: a target trial emulation","volume":"48","author":"Lagerberg","year":"2023","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.jad.2026.121175_bb0170","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1002\/jum.16081","article-title":"Transcranial sonography as a diagnostic tool for depressive disorders","volume":"42","author":"Li","year":"2023","journal-title":"J. Ultrasound Med."},{"key":"10.1016\/j.jad.2026.121175_bb0175","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1212\/01.WNL.0000148597.52312.9E","article-title":"A functional serotonin transporter gene polymorphism is associated with migraine with aura","volume":"64","author":"Marziniak","year":"2005","journal-title":"Neurology"},{"key":"10.1016\/j.jad.2026.121175_bb0180","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.jad.2011.10.043","article-title":"A morphometric, immunohistochemical, and in situ hybridization study of the dorsal raphe nucleus in major depression, bipolar disorder, schizophrenia, and suicide","volume":"137","author":"Matthews","year":"2012","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2026.121175_bb0185","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.euroneuro.2023.10.003","article-title":"Whole-brain structural and functional neuroimaging of individuals who attempted suicide and people who did not: a systematic review and exploratory coordinate-based meta-analysis","volume":"79","author":"Meda","year":"2024","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.jad.2026.121175_bb0190","doi-asserted-by":"crossref","DOI":"10.1016\/j.jad.2025.05.031","article-title":"Haematological markers of inflammation in major depressive disorder (MDD) patients with suicidal behaviour: a systematic review and meta-analysis","volume":"385","author":"Moshfeghinia","year":"2025","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2026.121175_bb0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.psychres.2025.116607","article-title":"Interpretable machine learning approach for predicting clinically significant suicide risk: a case study of patients with major depressive disorder in Greece","volume":"351","author":"Ntakolia","year":"2025","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.jad.2026.121175_bb0200","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1176\/appi.ajp.2014.14020194","article-title":"Toward a biosignature for suicide","volume":"171","author":"Oquendo","year":"2014","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.jad.2026.121175_bb0205","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1001\/jamapsychiatry.2016.1478","article-title":"Positron emission tomographic imaging of the serotonergic system and prediction of risk and lethality of future suicidal behavior","volume":"73","author":"Oquendo","year":"2016","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.jad.2026.121175_bb0210","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.jad.2015.12.066","article-title":"Identifying a clinical signature of suicidality among patients with mood disorders: a pilot study using a machine learning approach","volume":"193","author":"Passos","year":"2016","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2026.121175_bb0215","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1002\/mds.27035","article-title":"Application of the movement disorder society prodromal Parkinson's disease research criteria in 2 independent prospective cohorts","volume":"32","author":"Pilotto","year":"2017","journal-title":"Mov. Disord."},{"key":"10.1016\/j.jad.2026.121175_bb0220","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1055\/a-2296-3484","article-title":"Brainstem raphe hypoechogenicity is an independent predictor of post-stroke depression","volume":"46","author":"Richter","year":"2025","journal-title":"Ultraschall. Med."},{"key":"10.1016\/j.jad.2026.121175_bb0225","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.pscychresns.2015.09.010","article-title":"Transcranial sonography of brainstem structures in panic disorder","volume":"234","author":"\u0160ilh\u00e1n","year":"2015","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.jad.2026.121175_bb0230","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1176\/jnp.10.1.85","article-title":"The motor agitation and retardation scale: a scale for the assessment of motor abnormalities in depressed patients","volume":"10","author":"Sobin","year":"1998","journal-title":"J. Neuropsychiatry Clin. Neurosci."},{"key":"10.1016\/j.jad.2026.121175_bb0235","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0277316","article-title":"Reduced midbrain raphe echogenicity in patients with fibromyalgia syndrome","volume":"17","author":"\u00dc\u00e7eyler","year":"2022","journal-title":"PloS One"},{"key":"10.1016\/j.jad.2026.121175_bb0240","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1007\/s00415-015-7745-0","article-title":"Brainstem raphe and substantia nigra echogenicity in idiopathic REM sleep behavior disorder with comorbid depression","volume":"262","author":"Vilas","year":"2015","journal-title":"J. Neurol."},{"key":"10.1016\/j.jad.2026.121175_bb0245","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1093\/brain\/awm017","article-title":"Parkinson's disease-like midbrain sonography abnormalities are frequent in depressive disorders","volume":"130","author":"Walter","year":"2007","journal-title":"Brain"},{"key":"10.1016\/j.jad.2026.121175_bb0250","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.pscychresns.2006.12.001","article-title":"Relationship of brainstem raphe echogenicity and clinical findings in depressive states","volume":"155","author":"Walter","year":"2007","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.jad.2026.121175_bb0255","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.neuroimage.2007.12.019","article-title":"Contemporary ultrasound systems allow high-resolution transcranial imaging of small echogenic deep intracranial structures similarly as MRI: a phantom study","volume":"40","author":"Walter","year":"2008","journal-title":"Neuroimage"},{"key":"10.1016\/j.jad.2026.121175_bb0260","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1007\/s00702-014-1313-0","article-title":"Prediction of Parkinson\u2019s disease subsequent to severe depression: a ten-year follow-up study","volume":"122","author":"Walter","year":"2015","journal-title":"J. Neural Transm. (Vienna)"},{"key":"10.1016\/j.jad.2026.121175_bb0265","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1111\/sltb.12660","article-title":"The role of the 5-HTTLPR polymorphism in acquired capability for suicide","volume":"50","author":"Wannemueller","year":"2020","journal-title":"Suicide Life Threat. Behav."},{"key":"10.1016\/j.jad.2026.121175_bb0270","series-title":"WHO Policy Brief on the Health Aspects of Decriminalization of Suicide and Suicide Attempts","author":"World Health Organization","year":"2023"}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032726000261?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032726000261?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T20:26:01Z","timestamp":1777494361000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165032726000261"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":55,"alternative-id":["S0165032726000261"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2026.121175","relation":{},"ISSN":["0165-0327"],"issn-type":[{"value":"0165-0327","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transcranial sonography of the brainstem raphe: A rapid tool to assess the long-term risk of violent suicidal behavior in patients with major depression","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2026.121175","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"121175"}}