{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T22:07:09Z","timestamp":1780956429484,"version":"3.54.1"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T00:00:00Z","timestamp":1773619200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MR\/Y008502\/1"],"award-info":[{"award-number":["MR\/Y008502\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000005","name":"US Department of Defense","doi-asserted-by":"publisher","award":["TP220158"],"award-info":[{"award-number":["TP220158"]}],"id":[{"id":"10.13039\/100000005","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014013","name":"UK Research and Innovation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014013","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["R01-NS-094003-06A1"],"award-info":[{"award-number":["R01-NS-094003-06A1"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["U54NS115322"],"award-info":[{"award-number":["U54NS115322"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.jad.2026.121629","type":"journal-article","created":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T17:01:15Z","timestamp":1773421275000},"page":"121629","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Depression is both a risk factor for and outcome from traumatic brain injury in UK Biobank (N\u00a0=\u00a0502,356)"],"prefix":"10.1016","volume":"406","author":[{"given":"Mia","family":"Mantyla","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Russell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingxing","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"McCabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Stewart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald M.","family":"Lyall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jad.2026.121629_bb0005","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1080\/02699052.2020.1797169","article-title":"The management of depression following traumatic brain injury: A systematic review with meta-analysis","volume":"34","author":"Beedham","year":"2020","journal-title":"Brain Inj."},{"key":"10.1016\/j.jad.2026.121629_bb0010","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1001\/jama.2010.599","article-title":"Rates of Major Depressive Disorder and Clinical Outcomes Following Traumatic Brain Injury","volume":"303","author":"Bombardier","year":"2010","journal-title":"JAMA"},{"key":"10.1016\/j.jad.2026.121629_bb0015","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1016\/S0140-6736(12)60404-8","article-title":"What makes UK Biobank special?","volume":"379","author":"Collins","year":"2012","journal-title":"Lancet"},{"key":"10.1016\/j.jad.2026.121629_bb0020","article-title":"Mental health in UK Biobank \u2013 development, implementation and results from an online questionnaire completed by 157 366 participants: a reanalysis","volume":"6","author":"Davis","year":"2020"},{"key":"10.1016\/j.jad.2026.121629_bb0025","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1002\/pmrj.12657","article-title":"Prevalence of depression and anxiety disorders following mild traumatic brain injury","volume":"14","author":"Delmonico","year":"2022","journal-title":"PM&R."},{"key":"10.1016\/j.jad.2026.121629_bb0030","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.3171\/2017.10.JNS17352","article-title":"Estimating the global incidence of traumatic brain injury","volume":"130","author":"Dewan","year":"2018","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.jad.2026.121629_bb0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2023.e12905","article-title":"Psychiatric disorders in post-traumatic brain injury patients: A scoping review","volume":"9","author":"Duarte","year":"2023","journal-title":"Heliyon"},{"key":"10.1016\/j.jad.2026.121629_bb0040","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1001\/archpsyc.61.1.53","article-title":"Psychiatric Illness Following Traumatic Brain Injury in an Adult HealthMaintenance Organization Population","volume":"61","author":"Fann","year":"2004","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.jad.2026.121629_bb0045","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1017\/S0265021507003250","article-title":"Long-term psychiatric disorders after traumatic brain injury","volume":"25","author":"Fleminger","year":"2008","journal-title":"European Journal of Anaesthesiology | EJA."},{"key":"10.1016\/j.jad.2026.121629_bb0050","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1093\/aje\/kwx246","article-title":"Comparison of Sociodemographic and Health-Related Characteristics of UK Biobank Participants With Those of the General Population","volume":"186","author":"Fry","year":"2017","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.jad.2026.121629_bb0055","doi-asserted-by":"crossref","DOI":"10.1192\/bjo.2020.145","article-title":"Multiple measures of depression to enhance validity of major depressive disorder in the UK Biobank","volume":"7","author":"Glanville","year":"2021","journal-title":"BJPsych Open."},{"key":"10.1016\/j.jad.2026.121629_bb0060","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0113871","article-title":"Personality Change following Internet-Based Cognitive Behavior Therapy for Severe Health Anxiety","volume":"9","author":"Hedman","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.jad.2026.121629_bb0065","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1001\/archpsyc.59.1.17","article-title":"Head injury in early adulthood and the lifetime risk of depression","volume":"59","author":"Holsinger","year":"2002","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.jad.2026.121629_bb0070","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.biopsych.2021.09.024","article-title":"Mental Health Consequences of Traumatic Brain Injury","volume":"91","author":"Howlett","year":"2022","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2026.121629_bb0075","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0229489","article-title":"Adolescent traumatic brain injuries: Onset, mechanism and links with current academic performance and physical injuries","volume":"15","author":"Ilie","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.jad.2026.121629_bb0080","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2022.9478","article-title":"Association of Traumatic Brain Injury With the Risk of Developing Chronic Cardiovascular, Endocrine, Neurological, and Psychiatric Disorders","volume":"5","author":"Izzy","year":"2022","journal-title":"JAMA Netw. Open"},{"key":"10.1016\/j.jad.2026.121629_bb0085","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1016\/S1474-4422(17)30362-9","article-title":"Traumatic brain injury: a global challenge","volume":"16","author":"Johnson","year":"2017","journal-title":"The Lancet Neurology."},{"key":"10.1016\/j.jad.2026.121629_bb0090","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1176\/appi.ajp.159.8.1315","article-title":"Axis I and II Psychiatric Disorders After Traumatic Brain Injury: A 30-Year Follow-Up Study","volume":"159","author":"Koponen","year":"2002","journal-title":"AJP"},{"key":"10.1016\/j.jad.2026.121629_bb0095","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1038\/s41582-023-00853-8","article-title":"Psychiatric sequelae of traumatic brain injury \u2014 future directions in research","volume":"19","author":"Li","year":"2023","journal-title":"Nat. Rev. Neurol."},{"key":"10.1016\/j.jad.2026.121629_bb0100","doi-asserted-by":"crossref","first-page":"e198","DOI":"10.7861\/clinmed.2020-0336","article-title":"Management of traumatic brain injury (TBI): a clinical neuroscience-led pathway for the NHS","volume":"21","author":"Li","year":"2021","journal-title":"Clin. Med."},{"key":"10.1016\/j.jad.2026.121629_bb0105","series-title":"History of traumatic brain injury is associated with impaired cognition and imaging evidence of altered white matter tract integrity in UK Biobank (n=47,920)","author":"Lyall","year":"2022"},{"key":"10.1016\/j.jad.2026.121629_bb0110","doi-asserted-by":"crossref","first-page":"287","DOI":"10.31887\/DCNS.2011.13.2\/tmcallister","article-title":"Neurobiological consequences of traumatic brain injury","volume":"13","author":"McAllister","year":"2011","journal-title":"Dialogues Clin. Neurosci."},{"key":"10.1016\/j.jad.2026.121629_bb0115","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.apmr.2014.08.009","article-title":"Prevalence and Predictors of Personality Change After Severe Brain Injury","volume":"96","author":"Norup","year":"2015","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"10.1016\/j.jad.2026.121629_bb0120","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neubiorev.2014.07.007","article-title":"Depression following adult, non-penetrating traumatic brain injury: A meta-analysis examining methodological variables and sample characteristics","volume":"47","author":"Osborn","year":"2014","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.jad.2026.121629_bb0125","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1089\/neu.2017.5379","article-title":"Depression in the First Year after Traumatic Brain Injury","volume":"35","author":"Ouellet","year":"2018","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.jad.2026.121629_bb0130","doi-asserted-by":"crossref","first-page":"511","DOI":"10.3171\/2015.2.JNS14503","article-title":"Association of traumatic brain injury with subsequent neurological and psychiatric disease: a meta-analysis","volume":"124","author":"Perry","year":"2016","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.jad.2026.121629_bb0135","doi-asserted-by":"crossref","first-page":"e58","DOI":"10.1016\/S2666-7568(20)30007-6","article-title":"Associations between physical frailty and dementia incidence: a prospective study from UK Biobank","volume":"1","author":"Petermann-Rocha","year":"2020","journal-title":"Lancet Healthy Longev."},{"key":"10.1016\/j.jad.2026.121629_bb0140","doi-asserted-by":"crossref","first-page":"111","DOI":"10.2165\/11599560-000000000-00000","article-title":"Depression Following Traumatic Brain Injury","volume":"26","author":"Rapoport","year":"2012","journal-title":"CNS Drugs"},{"key":"10.1016\/j.jad.2026.121629_bb0145","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0075362","article-title":"Prevalence and Characteristics of Probable Major Depression and Bipolar Disorder within UK Biobank: Cross-Sectional Study of 172,751 Participants","volume":"8","author":"Smith","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jad.2026.121629_bb0150","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1017\/S0047279400020341","article-title":"Deprivation","volume":"16","author":"Townsend","year":"1987","journal-title":"J. Soc. Policy"}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032726004805?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032726004805?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T21:50:18Z","timestamp":1780955418000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165032726004805"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":30,"alternative-id":["S0165032726004805"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2026.121629","relation":{},"ISSN":["0165-0327"],"issn-type":[{"value":"0165-0327","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Depression is both a risk factor for and outcome from traumatic brain injury in UK Biobank (N\u00a0=\u00a0502,356)","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2026.121629","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"121629"}}