{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T18:32:33Z","timestamp":1793385153602,"version":"4.5.0"},"reference-count":49,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.jad.2026.122333","type":"journal-article","created":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T15:02:59Z","timestamp":1785250979000},"page":"122333","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Dimensional effect profiles in treatment-resistant depression: A naturalistic, prospective head-to-head comparison of arTMS, esketamine nasal spray, and oral brexpiprazole"],"prefix":"10.1016","volume":"414","author":[{"given":"Giacomo","family":"d'Andrea","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Cavallotto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ottavia","family":"Susini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Marsico","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanna","family":"Mammarella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianfranco","family":"Tamagnini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Inserra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluca","family":"Mancusi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgio","family":"Di Lorenzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tommaso","family":"Barlattani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Pacitti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro","family":"Pettorruso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Martinotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"25","key":"10.1016\/j.jad.2026.122333_bb0005","doi-asserted-by":"crossref","first-page":"2315","DOI":"10.1056\/NEJMoa2302399","article-title":"Ketamine versus ECT for nonpsychotic treatment-resistant major depression","volume":"388","author":"Anand","year":"2023","journal-title":"N. Engl. J. Med."},{"issue":"7","key":"10.1016\/j.jad.2026.122333_bb0010","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1176\/appi.ajp.2018.17060720","article-title":"Efficacy and safety of intranasal Esketamine for the rapid reduction of symptoms of depression and suicidality in patients at imminent risk for suicide: results of a double-blind, randomized, placebo-controlled study","volume":"175","author":"Canuso","year":"2018","journal-title":"Am. J. Psychiatry"},{"issue":"5","key":"10.1016\/j.jad.2026.122333_bb0015","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1097\/JCP.0000000000001465","article-title":"Esketamine nasal spray for the rapid reduction of depressive symptoms in major depressive disorder with acute suicidal ideation or behavior","volume":"41","author":"Canuso","year":"2021","journal-title":"J. Clin. Psychopharmacol."},{"issue":"1","key":"10.1016\/j.jad.2026.122333_bb0020","doi-asserted-by":"crossref","first-page":"6","DOI":"10.53941\/cna.2025.100006","article-title":"Novel perspectives for glutamatergic strategies, psychedelics and antipsychotic augmentation in treatment resistant depression: a narrative review","volume":"1","author":"Cavallotto","year":"2025","journal-title":"Clin. Neuropsychopharmacol. Addict."},{"issue":"9","key":"10.1016\/j.jad.2026.122333_bb0025","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1080\/14737175.2019.1653759","article-title":"Brexpiprazole as an augmentation agent to antidepressants in treatment resistant major depressive disorder","volume":"19","author":"Cha","year":"2019","journal-title":"Expert. Rev. Neurother."},{"issue":"9","key":"10.1016\/j.jad.2026.122333_bb0030","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1001\/jamapsychiatry.2019.1189","article-title":"Efficacy of esketamine nasal spray plus oral antidepressant treatment for relapse prevention in patients with treatment-resistant depression: a randomized clinical trial","volume":"76","author":"Daly","year":"2019","journal-title":"JAMA Psychiatry."},{"issue":"11","key":"10.1016\/j.jad.2026.122333_bb0035","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1002\/da.23193","article-title":"The effect of esketamine in patients with treatment-resistant depression with and without comorbid anxiety symptoms or disorder","volume":"38","author":"Daly","year":"2021","journal-title":"Depress. Anxiety"},{"key":"10.1016\/j.jad.2026.122333_bb0040","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.jad.2024.09.004","article-title":"Exploring vortioxetine combination with intranasal esketamine: a feasible alternative to SSRI\/SNRI? - insights from the REAL-ESK study","volume":"367","author":"d\u2019Andrea","year":"2024","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2026.122333_bb0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.psychres.2025.116655","article-title":"Effectiveness of repeated Esketamine nasal spray administration on anhedonic symptoms in treatment-resistant bipolar and unipolar depression: a secondary analysis from the REAL-ESK study group","volume":"352","author":"d\u2019Andrea","year":"2025","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.jad.2026.122333_bb0050","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.jad.2024.09.159","article-title":"An open-label pilot trial of a five-day, accelerated rTMS protocol in bipolar II depression","volume":"369","author":"d\u2019Andrea","year":"2025","journal-title":"J. Affect. Disord."},{"issue":"3","key":"10.1016\/j.jad.2026.122333_bb0060","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1002\/wps.20910","article-title":"Thinking too much: rumination and psychopathology","volume":"20","author":"Ehring","year":"2021","journal-title":"World Psychiatry"},{"key":"10.1016\/j.jad.2026.122333_bb0065","doi-asserted-by":"crossref","DOI":"10.1177\/20451253251394127","article-title":"Intravenous ketamine versus esketamine for depression: a systematic review and meta-analysis","volume":"15","author":"Elmosalamy","year":"2025","journal-title":"Ther. Adv. Psychopharmacol."},{"issue":"4","key":"10.1016\/j.jad.2026.122333_bb0070","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1176\/appi.ajp.2017.17060647","article-title":"Ketamine for rapid reduction of suicidal thoughts in major depression: a midazolam-controlled randomized clinical trial","volume":"175","author":"Grunebaum","year":"2018","journal-title":"Am. J. Psychiatry"},{"issue":"43","key":"10.1016\/j.jad.2026.122333_bb0075","doi-asserted-by":"crossref","first-page":"11496","DOI":"10.1523\/JNEUROSCI.2213-07.2007","article-title":"NMDA receptor hypofunction produces opposite effects on prefrontal cortex interneurons and pyramidal neurons","volume":"27","author":"Homayoun","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jad.2026.122333_bb0080","doi-asserted-by":"crossref","DOI":"10.1177\/20451253231151327","article-title":"Ketamine and esketamine in suicidal thoughts and behaviors: a systematic review","volume":"13","author":"Jollant","year":"2023","journal-title":"Ther. Adv. Psychopharmacol."},{"key":"10.1016\/j.jad.2026.122333_bb0085","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.euroneuro.2022.02.001","article-title":"Is treatment-resistant depression really resistant?","volume":"58","author":"Kasper","year":"2022","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.jad.2026.122333_bb0090","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.jad.2022.08.021","article-title":"Efficacy of adjunctive brexpiprazole on symptom clusters of major depressive disorder: A post hoc analysis of four clinical studies","volume":"316","author":"Katzman","year":"2022","journal-title":"J. Affect. Disord."},{"issue":"1","key":"10.1016\/j.jad.2026.122333_bb0095","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1146\/annurev-med-051322-120608","article-title":"Ketamine: mechanisms and relevance to treatment of depression","volume":"75","author":"Kim","year":"2024","journal-title":"Annu. Rev. Med."},{"issue":"3","key":"10.1016\/j.jad.2026.122333_bb0100","first-page":"285","article-title":"Ketamine modulates the neural correlates of reward processing in unmedicated patients in remission from depression","volume":"7","author":"Kotoula","year":"2022","journal-title":"Biol. Psychiatry: Cognit. Neurosci. Neuroimaging"},{"key":"10.1016\/j.jad.2026.122333_bb0105","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.euroneuro.2024.04.014","article-title":"Ketamine treatment for anhedonia in unipolar and bipolar depression: a systematic review","volume":"86","author":"Kwa\u015bny","year":"2024","journal-title":"Eur. Neuropsychopharmacol."},{"issue":"10","key":"10.1016\/j.jad.2026.122333_bb0110","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2014.105","article-title":"Anti-anhedonic effect of ketamine and its neural correlates in treatment-resistant bipolar depression","volume":"4","author":"Lally","year":"2014","journal-title":"Transl. Psychiatry"},{"issue":"5994","key":"10.1016\/j.jad.2026.122333_bb0115","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1126\/science.1190287","article-title":"mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists","volume":"329","author":"Li","year":"2010","journal-title":"Science"},{"issue":"2","key":"10.1016\/j.jad.2026.122333_bb0120","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1177\/0269881120978398","article-title":"Repeated subcutaneous esketamine for treatment-resistant depression: impact of the degree of treatment resistance and anxiety comorbidity","volume":"35","author":"Lucchese","year":"2021","journal-title":"J. Psychopharmacol. (Oxf.)"},{"issue":"3","key":"10.1016\/j.jad.2026.122333_bb0125","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1002\/wps.20771","article-title":"The clinical characterization of the adult patient with depression aimed at personalization of management","volume":"19","author":"Maj","year":"2020","journal-title":"World Psychiatry"},{"issue":"1","key":"10.1016\/j.jad.2026.122333_bb0130","doi-asserted-by":"crossref","DOI":"10.4088\/JCP.25cs16066","article-title":"Next-step treatment options for treatment-resistant depression: insights from the Mayo Clinic depression center panel","volume":"87","author":"Marques","year":"2026","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.jad.2026.122333_bb0135","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/j.jad.2022.09.043","article-title":"Real-world experience of esketamine use to manage treatment-resistant depression: a multicentric study on safety and effectiveness (REAL-ESK study)","volume":"319","author":"Martinotti","year":"2022","journal-title":"J. Affect. Disord."},{"issue":"3","key":"10.1016\/j.jad.2026.122333_bb0140","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1111\/bdi.13296","article-title":"Treating bipolar depression with esketamine: safety and effectiveness data from a naturalistic multicentric study on esketamine in bipolar versus unipolar treatment-resistant depression","volume":"25","author":"Martinotti","year":"2023","journal-title":"Bipolar Disord."},{"issue":"Suppl. 1","key":"10.1016\/j.jad.2026.122333_bb0145","doi-asserted-by":"crossref","first-page":"9","DOI":"10.4088\/JCP.14077su1c.02","article-title":"Implementing Treatment Strategies for Different Types of Depression","volume":"77","author":"McIntyre","year":"2016","journal-title":"J Clin Psychiatry."},{"issue":"3","key":"10.1016\/j.jad.2026.122333_bb0150","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1002\/wps.21120","article-title":"Treatment-resistant depression: definition, prevalence, detection, management, and investigational interventions","volume":"22","author":"McIntyre","year":"2023","journal-title":"World Psychiatry"},{"key":"10.1016\/j.jad.2026.122333_bb0155","doi-asserted-by":"crossref","DOI":"10.1017\/neu.2024.32","article-title":"A double-blind, placebo-controlled, randomised withdrawal study of adjunctive brexpiprazole maintenance treatment for major depressive disorder","volume":"37","author":"McIntyre","year":"2025","journal-title":"Acta Neuropsychiatr."},{"issue":"7","key":"10.1016\/j.jad.2026.122333_bb0160","doi-asserted-by":"crossref","first-page":"3292","DOI":"10.1038\/s41380-020-00878-1","article-title":"Ketamine modulates fronto-striatal circuitry in depressed and healthy individuals","volume":"26","author":"Mkrtchian","year":"2021","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jad.2026.122333_bb0165","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.jad.2024.08.114","article-title":"Brain mechanisms of rumination and negative self-referential processing in adolescent depression","volume":"366","author":"Murray","year":"2024","journal-title":"J Affect Disord. dicembre"},{"issue":"7","key":"10.1016\/j.jad.2026.122333_bb0170","doi-asserted-by":"crossref","first-page":"2011","DOI":"10.1007\/s00213-022-06105-9","article-title":"The effect of ketamine on anhedonia: improvements in dimensions of anticipatory, consummatory, and motivation-related reward deficits","volume":"239","author":"Nogo","year":"2022","journal-title":"Psychopharmacology"},{"issue":"2","key":"10.1016\/j.jad.2026.122333_bb0175","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.jagp.2019.10.008","article-title":"Efficacy and safety of Esketamine nasal spray plus an oral antidepressant in elderly patients with treatment-resistant depression\u2014TRANSFORM-3","volume":"28","author":"Ochs-Ross","year":"2020","journal-title":"Am. J. Geriatr. Psychiatry"},{"issue":"6","key":"10.1016\/j.jad.2026.122333_bb0180","article-title":"Depressione resistente a trattamento. Dalla classificazione alle nuove terapie","volume":"0","author":"Paganin","year":"2022","journal-title":"Riv. Psichiatr."},{"issue":"17","key":"10.1016\/j.jad.2026.122333_bb0185","doi-asserted-by":"crossref","first-page":"4181","DOI":"10.1111\/bph.15596","article-title":"Perspectives for therapy of treatment-resistant depression","volume":"179","author":"Papp","year":"2022","journal-title":"Br. J. Pharmacol."},{"issue":"4","key":"10.1016\/j.jad.2026.122333_bb0190","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1016\/j.brs.2023.06.003","article-title":"Comparing fast-acting interventions for treatment-resistant depression: an explorative study of accelerated HF-rTMS versus intranasal esketamine","volume":"16","author":"Pettorruso","year":"2023","journal-title":"Brain Stimul."},{"issue":"6","key":"10.1016\/j.jad.2026.122333_bb0195","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1176\/appi.ajp.2019.19020172","article-title":"Efficacy and safety of flexibly dosed esketamine nasal spray combined with a newly initiated oral antidepressant in treatment-resistant depression: a randomized double-blind active-controlled study","volume":"176","author":"Popova","year":"2019","journal-title":"Am. J. Psychiatry"},{"issue":"14","key":"10.1016\/j.jad.2026.122333_bb0200","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1056\/NEJMoa2304145","article-title":"Esketamine nasal spray versus quetiapine for treatment-resistant depression","volume":"389","author":"Reif","year":"2023","journal-title":"N. Engl. J. Med."},{"issue":"3","key":"10.1016\/j.jad.2026.122333_bb0205","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1038\/s41380-021-01381-x","article-title":"A Delphi-method-based consensus guideline for definition of treatment-resistant depression for clinical trials","volume":"27","author":"Sforzini","year":"2022","journal-title":"Mol. Psychiatry"},{"issue":"1","key":"10.1016\/j.jad.2026.122333_bb0210","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1038\/s41398-024-02973-1","article-title":"A meta-analysis of the effects of ketamine on suicidal ideation in depression patients","volume":"14","author":"Shen","year":"2024","journal-title":"Transl. Psychiatry"},{"issue":"3","key":"10.1016\/j.jad.2026.122333_bb0215","doi-asserted-by":"crossref","first-page":"397","DOI":"10.3390\/brainsci13030397","article-title":"Brexpiprazole\u2014pharmacologic properties and use in schizophrenia and mood disorders","volume":"13","author":"Siwek","year":"2023","journal-title":"Brain Sci."},{"issue":"1","key":"10.1016\/j.jad.2026.122333_bb0220","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.brs.2025.01.005","article-title":"Repetitive transcranial magnetic stimulation for the treatment of suicidal ideation in a naturalistic setting","volume":"18","author":"Stapper","year":"2025","journal-title":"Brain Stimul."},{"issue":"12","key":"10.1016\/j.jad.2026.122333_bb0225","doi-asserted-by":"crossref","first-page":"5150","DOI":"10.1038\/s41380-023-02159-z","article-title":"Neural mechanisms of emotional health in traumatic brain injury patients undergoing rTMS treatment","volume":"28","author":"Sultana","year":"2023","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.jad.2026.122333_bb0230","doi-asserted-by":"crossref","first-page":"221","DOI":"10.2147\/NDT.S198774","article-title":"Management of treatment-resistant depression: challenges and strategies","volume":"16","author":"Voineskos","year":"2020","journal-title":"Neuropsychiatr. Dis. Treat."},{"key":"10.1016\/j.jad.2026.122333_bb0235","series-title":"Depressive Disorder (Depression) \u2013 Fact Sheet [Report] [Internet]","author":"World Health Organization","year":"2025"},{"issue":"20","key":"10.1016\/j.jad.2026.122333_bb0240","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1001\/jama.2013.281053","article-title":"World medical association declaration of Helsinki: ethical principles for medical research involving human subjects","volume":"310","author":"World Medical Association","year":"2013","journal-title":"JAMA"},{"issue":"1","key":"10.1016\/j.jad.2026.122333_bb0245","doi-asserted-by":"crossref","DOI":"10.1192\/j.eurpsy.2024.1769","article-title":"Exploring potential working mechanisms of accelerated HF-rTMS in refractory major depression with a focus on locus coeruleus connectivity","volume":"67","author":"Wu","year":"2024","journal-title":"Eur. Psychiatry"},{"key":"10.1016\/j.jad.2026.122333_bb0250","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.jad.2021.12.105","article-title":"Comparative effectiveness of repeated ketamine infusions in treating anhedonia in bipolar and unipolar depression","volume":"300","author":"Zheng","year":"2022","journal-title":"J. Affect. Disord."}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032726011869?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032726011869?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T17:58:50Z","timestamp":1793383130000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165032726011869"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":49,"alternative-id":["S0165032726011869"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2026.122333","relation":{},"ISSN":["0165-0327"],"issn-type":[{"value":"0165-0327","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dimensional effect profiles in treatment-resistant depression: A naturalistic, prospective head-to-head comparison of arTMS, esketamine nasal spray, and oral brexpiprazole","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2026.122333","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"122333"}}