{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T17:38:09Z","timestamp":1792777089188,"version":"4.5.0"},"reference-count":82,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2027,10,23]],"date-time":"2027-10-23T00:00:00Z","timestamp":1824249600000},"content-version":"am","delay-in-days":295,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2027,1]]},"DOI":"10.1016\/j.jad.2026.122644","type":"journal-article","created":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T14:58:19Z","timestamp":1792162699000},"page":"122644","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Aberrant amygdala subregion volumes in youth at high risk for bipolar disorder predict antidepressant-induced adverse events"],"prefix":"10.1016","volume":"417","author":[{"given":"Biqiu","family":"Tang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. Rodrigo","family":"Patino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas J.","family":"Blom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey A.","family":"Welge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey R.","family":"Strawn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaitlyn M.","family":"Bruns","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Su","family":"Lui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa P.","family":"DelBello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manpreet K.","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jad.2026.122644_bb0005","series-title":"The Amygdala: A Functional Analysis","author":"Aggleton","year":"2000"},{"issue":"10","key":"10.1016\/j.jad.2026.122644_bb0010","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1001\/archpsyc.1977.01770220111013","article-title":"The family history method using diagnostic criteria. Reliability and validity","volume":"34","author":"Andreasen","year":"1977","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.jad.2026.122644_bb0015","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.schres.2019.10.014","article-title":"Amygdala subnucleus volumes in psychosis high-risk state and first-episode psychosis","volume":"215","author":"Armio","year":"2020","journal-title":"Schizophr. Res."},{"issue":"3","key":"10.1016\/j.jad.2026.122644_bb0020","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1046\/j.1471-4159.2001.00437.x","article-title":"Regional changes in density of serotonin transporter in the brain of 5-HT1A and 5-HT1B knockout mice, and of serotonin innervation in the 5-HT1B knockout","volume":"78","author":"Ase","year":"2001","journal-title":"J. Neurochem."},{"issue":"5","key":"10.1016\/j.jad.2026.122644_bb0025","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1093\/schbul\/sbaa192","article-title":"In vivo amygdala nuclei volumes in schizophrenia and bipolar disorders","volume":"47","author":"Barth","year":"2021","journal-title":"Schizophr. Bull."},{"issue":"1","key":"10.1016\/j.jad.2026.122644_bb0030","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.neuroscience.2005.07.040","article-title":"The distribution of serotonergic fibers in the macaque monkey amygdala: an immunohistochemical study using antisera to 5-hydroxytryptamine","volume":"136","author":"Bauman","year":"2005","journal-title":"Neuroscience"},{"issue":"1","key":"10.1016\/j.jad.2026.122644_bb0035","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.pscychresns.2011.06.010","article-title":"Amygdala and insula volumes prior to illness onset in bipolar disorder: a magnetic resonance imaging study","volume":"201","author":"Bechdolf","year":"2012","journal-title":"Psychiatry Res."},{"issue":"8","key":"10.1016\/j.jad.2026.122644_bb0040","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1016\/j.biopsych.2007.04.023","article-title":"Neuron numbers and volume of the amygdala in subjects diagnosed with bipolar disorder or schizophrenia","volume":"62","author":"Berretta","year":"2007","journal-title":"Biol. Psychiatry"},{"issue":"4","key":"10.1016\/j.jad.2026.122644_bb0045","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.jchemneu.2011.05.010","article-title":"Effects of citalopram on serotonin and CRF systems in the midbrain of primates with differences in stress sensitivity","volume":"41","author":"Bethea","year":"2011","journal-title":"J. Chem. Neuroanat."},{"issue":"3","key":"10.1016\/j.jad.2026.122644_bb0050","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1139\/jpn.0720","article-title":"Neuron somal size is decreased in the lateral amygdalar nucleus of subjects with bipolar disorder","volume":"32","author":"Bezchlibnyk","year":"2007","journal-title":"J. Psychiatry Neurosci."},{"issue":"6","key":"10.1016\/j.jad.2026.122644_bb0055","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/s00406-005-0581-y","article-title":"Volume deficits of subcortical nuclei in mood disorders: a postmortem study","volume":"255","author":"Bielau","year":"2005","journal-title":"Eur. Arch. Psychiatry Clin. Neurosci."},{"issue":"2","key":"10.1016\/j.jad.2026.122644_bb0060","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.neuroimage.2009.12.073","article-title":"The influence of directed covert attention on emotional face processing","volume":"50","author":"Brassen","year":"2010","journal-title":"Neuroimage"},{"issue":"3","key":"10.1016\/j.jad.2026.122644_bb0065","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.psychres.2012.09.019","article-title":"Psychometric properties of the treatment-emergent activation and suicidality assessment profile (TEASAP) in youth with OCD","volume":"205","author":"Bussing","year":"2013","journal-title":"Psychiatry Res."},{"issue":"12","key":"10.1016\/j.jad.2026.122644_bb0070","doi-asserted-by":"crossref","first-page":"3247","DOI":"10.1002\/hbm.22138","article-title":"An investigation of the structural, connectional, and functional subspecialization in the human amygdala","volume":"34","author":"Bzdok","year":"2013","journal-title":"Hum. Brain Mapp."},{"issue":"3","key":"10.1016\/j.jad.2026.122644_bb0075","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1111\/bdi.12720","article-title":"Neural signatures of the risk for bipolar disorder: A meta-analysis of structural and functional neuroimaging studies","volume":"21","author":"Cattarinussi","year":"2019","journal-title":"Bipolar Disord."},{"issue":"5","key":"10.1016\/j.jad.2026.122644_bb0080","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.biopsych.2022.02.960","article-title":"Neural correlates of the risk for schizophrenia and bipolar disorder: A Meta-analysis of structural and functional neuroimaging studies","volume":"92","author":"Cattarinussi","year":"2022","journal-title":"Biol. Psychiatry"},{"issue":"6","key":"10.1016\/j.jad.2026.122644_bb0085","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1097\/01.chi.0000159948.75136.0d","article-title":"Reduced amygdalar gray matter volume in familial pediatric bipolar disorder","volume":"44","author":"Chang","year":"2005","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"issue":"1","key":"10.1016\/j.jad.2026.122644_bb0090","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1002\/hbm.25098","article-title":"What we learn about bipolar disorder from large-scale neuroimaging: findings and future directions from the ENIGMA bipolar disorder working group","volume":"43","author":"Ching","year":"2022","journal-title":"Hum. Brain Mapp."},{"issue":"1","key":"10.1016\/j.jad.2026.122644_bb0095","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.tics.2007.10.011","article-title":"Serotoninergic regulation of emotional and behavioural control processes","volume":"12","author":"Cools","year":"2008","journal-title":"Trends Cogn. Sci."},{"key":"10.1016\/j.jad.2026.122644_bb0100","article-title":"Correlation between decreased amygdala subnuclei volumes and impaired cognitive functions in pediatric bipolar disorder","volume":"11","author":"Cui","year":"2020","journal-title":"Front. Psychol."},{"issue":"12","key":"10.1016\/j.jad.2026.122644_bb0105","doi-asserted-by":"crossref","first-page":"3358","DOI":"10.1002\/hbm.25021","article-title":"Amygdala subnuclei volume in bipolar spectrum disorders: insights from diffusion-based subsegmentation and a high-risk design","volume":"41","author":"Damme","year":"2020","journal-title":"Hum. Brain Mapp."},{"issue":"9","key":"10.1016\/j.jad.2026.122644_bb0110","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/j.tins.2010.05.005","article-title":"Serotonin: a regulator of neuronal morphology and circuitry","volume":"33","author":"Daubert","year":"2010","journal-title":"Trends Neurosci."},{"issue":"1","key":"10.1016\/j.jad.2026.122644_bb0115","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/sj.mp.4000812","article-title":"The amygdala: vigilance and emotion","volume":"6","author":"Davis","year":"2001","journal-title":"Mol. Psychiatry"},{"issue":"1","key":"10.1016\/j.jad.2026.122644_bb0120","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1046\/j.1399-5618.2003.00087.x","article-title":"Magnetic resonance imaging analysis of amygdala and other subcortical brain regions in adolescents with bipolar disorder","volume":"6","author":"DelBello","year":"2004","journal-title":"Bipolar Disord."},{"issue":"2","key":"10.1016\/j.jad.2026.122644_bb0125","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1017\/S0033291713000731","article-title":"Paradoxical effects of short-term antidepressant treatment in fMRI emotional processing models in volunteers with high neuroticism","volume":"44","author":"Di Simplicio","year":"2014","journal-title":"Psychol. Med."},{"key":"10.1016\/j.jad.2026.122644_bb0130","series-title":"Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I), Clinician Version (Administration Booklet)","author":"First","year":"1997"},{"issue":"11","key":"10.1016\/j.jad.2026.122644_bb0135","doi-asserted-by":"crossref","first-page":"2499","DOI":"10.1093\/cercor\/bhp022","article-title":"Medial prefrontal cortex 5-HT(2A) density is correlated with amygdala reactivity, response habituation, and functional coupling","volume":"19","author":"Fisher","year":"2009","journal-title":"Cerebral cortex (New York, N.Y. : 1991)"},{"key":"10.1016\/j.jad.2026.122644_bb0140","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.neuroimage.2017.11.024","article-title":"Harmonization of cortical thickness measurements across scanners and sites","volume":"167","author":"Fortin","year":"2018","journal-title":"Neuroimage"},{"issue":"7","key":"10.1016\/j.jad.2026.122644_bb0145","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1176\/appi.ajp.162.7.1256","article-title":"Structural brain magnetic resonance imaging of limbic and thalamic volumes in pediatric bipolar disorder","volume":"162","author":"Frazier","year":"2005","journal-title":"Am. J. Psychiatry"},{"issue":"2","key":"10.1016\/j.jad.2026.122644_bb0150","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/j.neuroscience.2009.01.013","article-title":"Amygdala projections to central amygdaloid nucleus subdivisions and transition zones in the primate","volume":"159","author":"Fudge","year":"2009","journal-title":"Neuroscience"},{"issue":"9","key":"10.1016\/j.jad.2026.122644_bb0155","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1097\/00004583-200209000-00006","article-title":"The pediatric anxiety rating scale (PARS): development and psychometric properties","volume":"41","author":"Group, R.U.o.P.P.A.S","year":"2002","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"issue":"6","key":"10.1016\/j.jad.2026.122644_bb0160","doi-asserted-by":"crossref","DOI":"10.3390\/jpm12061006","article-title":"A double-blind randomized trial to investigate mechanisms of antidepressant-related dysfunctional arousal in depressed or anxious youth at familial risk for bipolar disorder","volume":"12","author":"Honeycutt","year":"2022","journal-title":"J. Pers. Med."},{"issue":"3","key":"10.1016\/j.jad.2026.122644_bb0165","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.cell.2011.10.009","article-title":"Molecular mechanisms of fear learning and memory","volume":"147","author":"Johansen","year":"2011","journal-title":"Cell"},{"issue":"3","key":"10.1016\/j.jad.2026.122644_bb0170","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.pscychresns.2011.03.006","article-title":"Amygdalar, hippocampal, and thalamic volumes in youth at high risk for development of bipolar disorder","volume":"194","author":"Karchemskiy","year":"2011","journal-title":"Psychiatry Res."},{"issue":"7","key":"10.1016\/j.jad.2026.122644_bb0175","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1097\/00004583-199707000-00021","article-title":"Schedule for affective disorders and schizophrenia for school-age children-present and lifetime version (K-SADS-PL): initial reliability and validity data","volume":"36","author":"Kaufman","year":"1997","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"issue":"7","key":"10.1016\/j.jad.2026.122644_bb0180","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1111\/bdi.12114","article-title":"Deformations of amygdala morphology in familial pediatric bipolar disorder","volume":"15","author":"Kelley","year":"2013","journal-title":"Bipolar Disord."},{"issue":"1","key":"10.1016\/j.jad.2026.122644_bb0185","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1006\/nimg.2002.1323","article-title":"Dissociable neural pathways are involved in the recognition of emotion in static and dynamic facial expressions","volume":"18","author":"Kilts","year":"2003","journal-title":"Neuroimage"},{"key":"10.1016\/j.jad.2026.122644_bb0190","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.neubiorev.2017.03.007","article-title":"Serotonin and neuroplasticity - links between molecular, functional and structural pathophysiology in depression","volume":"77","author":"Kraus","year":"2017","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.jad.2026.122644_bb0195","first-page":"1","article-title":"Functional connectivity of the amygdala subnuclei in various mood states of bipolar disorder","author":"Krystal","year":"2024","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jad.2026.122644_bb0200","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.schres.2018.06.016","article-title":"Some neuroanatomical insights to impulsive aggression in schizophrenia","volume":"201","author":"Leclerc","year":"2018","journal-title":"Schizophr. Res."},{"issue":"3","key":"10.1016\/j.jad.2026.122644_bb0205","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1002\/ajpa.23896","article-title":"Serotonergic innervation of the human amygdala and evolutionary implications","volume":"170","author":"Lew","year":"2019","journal-title":"Am. J. Phys. Anthropol."},{"key":"10.1016\/j.jad.2026.122644_bb0210","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.jpsychires.2018.01.001","article-title":"Resting-state fMRI signals in offspring of parents with bipolar disorder at the high-risk and ultra-high-risk stages and their relations with cognitive function","volume":"98","author":"Lin","year":"2018","journal-title":"J. Psychiatr. Res."},{"issue":"2","key":"10.1016\/j.jad.2026.122644_bb0215","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1093\/schbul\/sbt044","article-title":"Differentiating patterns of amygdala-frontal functional connectivity in schizophrenia and bipolar disorder","volume":"40","author":"Liu","year":"2013","journal-title":"Schizophr. Bull."},{"issue":"5","key":"10.1016\/j.jad.2026.122644_bb0225","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1038\/s41386-021-01186-0","article-title":"Acute neurofunctional effects of escitalopram during emotional processing in pediatric anxiety: a double-blind, placebo-controlled trial","volume":"47","author":"Lu","year":"2022","journal-title":"Neuropsychopharmacology"},{"issue":"10","key":"10.1016\/j.jad.2026.122644_bb0220","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1016\/j.jaac.2020.11.023","article-title":"Acute neurofunctional effects of escitalopram in pediatric anxiety: a double-blind, placebo-controlled trial","volume":"60","author":"Lu","year":"2021","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"issue":"2","key":"10.1016\/j.jad.2026.122644_bb0230","first-page":"50","article-title":"Antidepressant-induced activation in children and adolescents: risk, recognition and management","volume":"48","author":"Luft","year":"2018","journal-title":"Curr. Probl. Pediatr. Adolesc. Health Care"},{"issue":"1","key":"10.1016\/j.jad.2026.122644_bb0235","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1017\/S003329171400110X","article-title":"Resting-state brain function in schizophrenia and psychotic bipolar probands and their first-degree relatives","volume":"45","author":"Lui","year":"2015","journal-title":"Psychol. Med."},{"key":"10.1016\/j.jad.2026.122644_bb0240","series-title":"The scientific proceedings of the 2007 annual meeting of the American Academy of Child and Adolescent Psychiatry","first-page":"23","article-title":"CAPTN: the pediatric adverse event rating scale","author":"March","year":"2007"},{"issue":"10","key":"10.1016\/j.jad.2026.122644_bb0245","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.tics.2011.08.003","article-title":"Large-scale brain networks and psychopathology: a unifying triple network model","volume":"15","author":"Menon","year":"2011","journal-title":"Trends Cogn. Sci."},{"issue":"2","key":"10.1016\/j.jad.2026.122644_bb0250","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1111\/j.1469-7580.2007.00780.x","article-title":"Evolution of the amygdaloid complex in vertebrates, with special reference to the anamnio-amniotic transition","volume":"211","author":"Moreno","year":"2007","journal-title":"J. Anat."},{"issue":"1","key":"10.1016\/j.jad.2026.122644_bb0255","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.biopsych.2023.06.022","article-title":"The genetic architecture of amygdala nuclei","volume":"95","author":"Mufford","year":"2024","journal-title":"Biol. Psychiatry"},{"issue":"10","key":"10.1016\/j.jad.2026.122644_bb0260","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1176\/appi.ajp.160.10.1830","article-title":"Pharmacogenetics of antidepressant medication intolerance","volume":"160","author":"Murphy","year":"2003","journal-title":"Am. J. Psychiatry"},{"issue":"12","key":"10.1016\/j.jad.2026.122644_bb0265","doi-asserted-by":"crossref","first-page":"3459","DOI":"10.1016\/j.neuropsychologia.2010.07.030","article-title":"fMRI studies of successful emotional memory encoding: A quantitative meta-analysis","volume":"48","author":"Murty","year":"2010","journal-title":"Neuropsychologia"},{"issue":"1","key":"10.1016\/j.jad.2026.122644_bb0270","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1590\/1516-4446-2019-0803","article-title":"Association between poor tolerability of antidepressant treatment and brain functional activation in youth at risk for bipolar disorder","volume":"43","author":"Nery","year":"2020","journal-title":"Braz. J. Psychiatry"},{"issue":"7","key":"10.1016\/j.jad.2026.122644_bb0275","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/j.jaac.2020.07.890","article-title":"Neural correlates of positive emotion processing that distinguish healthy youths at familial risk for bipolar versus major depressive disorder","volume":"60","author":"Nimarko","year":"2021","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"issue":"8","key":"10.1016\/j.jad.2026.122644_bb0280","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1111\/jcpp.13946","article-title":"Aberrant brain network topology in youth with a familial risk for bipolar disorder: a task-based fMRI connectome study","volume":"65","author":"Pan","year":"2024","journal-title":"J. Child Psychol. Psychiatry"},{"issue":"2","key":"10.1016\/j.jad.2026.122644_bb0285","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.pscychresns.2015.09.018","article-title":"Amygdalar volumetric correlates of social anxiety in offspring of parents with bipolar disorder","volume":"234","author":"Park","year":"2015","journal-title":"Psychiatry Res."},{"issue":"4","key":"10.1016\/j.jad.2026.122644_bb0290","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.neuropsychologia.2011.02.030","article-title":"Reprint of: emotion and cognition and the amygdala: from \"what is it?\" to \"what's to be done?\"","volume":"49","author":"Pessoa","year":"2011","journal-title":"Neuropsychologia"},{"issue":"11","key":"10.1016\/j.jad.2026.122644_bb0295","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1097\/CHI.0b013e318185d299","article-title":"Meta-analysis of amygdala volumes in children and adolescents with bipolar disorder","volume":"47","author":"Pfeifer","year":"2008","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"issue":"8","key":"10.1016\/j.jad.2026.122644_bb0300","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1176\/appi.ajp.2014.13081008","article-title":"A critical appraisal of neuroimaging studies of bipolar disorder: toward a new conceptualization of underlying neural circuitry and a road map for future research","volume":"171","author":"Phillips","year":"2014","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.jad.2026.122644_bb0305","series-title":"Children's Depression Rating Scale, Revised (CDRS-R)","author":"Poznanski","year":"1996"},{"issue":"3","key":"10.1016\/j.jad.2026.122644_bb0310","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1002\/(SICI)1099-0798(199822)16:3<319::AID-BSL311>3.0.CO;2-G","article-title":"Reduced prefrontal and increased subcortical brain functioning assessed using positron emission tomography in predatory and affective murderers","volume":"16","author":"Raine","year":"1998","journal-title":"Behav. Sci. Law"},{"issue":"1\u20133","key":"10.1016\/j.jad.2026.122644_bb0315","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.schres.2014.07.001","article-title":"Emotion recognition deficits in schizophrenia-spectrum disorders and psychotic bipolar disorder: findings from the bipolar-schizophrenia network on intermediate phenotypes (B-SNIP) study","volume":"158","author":"Ruocco","year":"2014","journal-title":"Schizophr. Res."},{"issue":"1","key":"10.1016\/j.jad.2026.122644_bb0320","first-page":"117","article-title":"Developmental variation in amygdala volumes: modeling differences across time, age, and puberty","volume":"6","author":"Russell","year":"2021","journal-title":"Biol. Psychiatry: Cognit. Neurosci. Neuroimaging"},{"issue":"3","key":"10.1016\/j.jad.2026.122644_bb0325","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1152\/physrev.00002.2003","article-title":"The amygdaloid complex: anatomy and physiology","volume":"83","author":"Sah","year":"2003","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.jad.2026.122644_bb0330","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.neuroimage.2017.04.046","article-title":"High-resolution magnetic resonance imaging reveals nuclei of the human amygdala: manual segmentation to automatic atlas","volume":"155","author":"Saygin","year":"2017","journal-title":"Neuroimage"},{"issue":"16","key":"10.1016\/j.jad.2026.122644_bb0335","doi-asserted-by":"crossref","first-page":"4805","DOI":"10.1002\/hbm.26005","article-title":"Amygdala subnuclei volumes and anxiety behaviors in children and adolescents with autism spectrum disorder, attention deficit hyperactivity disorder, and obsessive-compulsive disorder","volume":"43","author":"Seguin","year":"2022","journal-title":"Hum. Brain Mapp."},{"issue":"5","key":"10.1016\/j.jad.2026.122644_bb0340","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1097\/CHI.0b013e318167655a","article-title":"Neuroanatomical characterization of child offspring of bipolar parents","volume":"47","author":"Singh","year":"2008","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"issue":"9","key":"10.1016\/j.jad.2026.122644_bb0345","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/j.jaac.2015.06.016","article-title":"Intrinsic amygdala functional connectivity in youth with bipolar I disorder","volume":"54","author":"Singh","year":"2015","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"issue":"6","key":"10.1016\/j.jad.2026.122644_bb0350","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1080\/13803395.2017.1401597","article-title":"Vulnerabilities in sequencing and task switching in healthy youth offspring of parents with mood disorders","volume":"40","author":"Singh","year":"2018","journal-title":"J. Clin. Exp. Neuropsychol."},{"issue":"3","key":"10.1016\/j.jad.2026.122644_bb0355","doi-asserted-by":"crossref","first-page":"525","DOI":"10.12740\/PP\/109386","article-title":"Mania induced by antidepressants - characteristics and specific phenomena in children and adolescents","volume":"54","author":"Stawicka","year":"2020","journal-title":"Psychiatr. Pol."},{"issue":"5","key":"10.1016\/j.jad.2026.122644_bb0360","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1111\/bdi.12113","article-title":"Antidepressant tolerability in anxious and depressed youth at high risk for bipolar disorder: a prospective naturalistic treatment study","volume":"16","author":"Strawn","year":"2014","journal-title":"Bipolar Disord."},{"issue":"5","key":"10.1016\/j.jad.2026.122644_bb0365","doi-asserted-by":"crossref","DOI":"10.4088\/JCP.20m13396","article-title":"Escitalopram in adolescents with generalized anxiety disorder: a double-blind, randomized, placebo-controlled study","volume":"81","author":"Strawn","year":"2020","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.jad.2026.122644_bb0370","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.jpsychires.2023.01.043","article-title":"The impact of age on antidepressant response: A mega-analysis of individuals with major depressive disorder","volume":"159","author":"Strawn","year":"2023","journal-title":"J. Psychiatr. Res."},{"issue":"4","key":"10.1016\/j.jad.2026.122644_bb0375","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1176\/appi.ajp.2011.11040615","article-title":"Brain activity in adolescent major depressive disorder before and after fluoxetine treatment","volume":"169","author":"Tao","year":"2012","journal-title":"Am. J. Psychiatry"},{"issue":"2","key":"10.1016\/j.jad.2026.122644_bb0380","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S0006-3223(02)01743-2","article-title":"Frontolimbic brain abnormalities in patients with borderline personality disorder: a volumetric magnetic resonance imaging study","volume":"54","author":"Tebartz van Elst","year":"2003","journal-title":"Biol. Psychiatry"},{"issue":"1","key":"10.1016\/j.jad.2026.122644_bb0385","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.pscychresns.2009.09.004","article-title":"Correlation between amygdala volume and age in bipolar disorder - a systematic review and meta-analysis of structural MRI studies","volume":"182","author":"Usher","year":"2010","journal-title":"Psychiatry Res."},{"issue":"9","key":"10.1016\/j.jad.2026.122644_bb0390","doi-asserted-by":"crossref","first-page":"3652","DOI":"10.1073\/pnas.0709815105","article-title":"Prefrontal and amygdala volumes are related to adolescents' affective behaviors during parent-adolescent interactions","volume":"105","author":"Whittle","year":"2008","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"6","key":"10.1016\/j.jad.2026.122644_bb0395","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1002\/jnr.23683","article-title":"Basolateral but not corticomedial amygdala shows neuroarchitectural changes in schizophrenia","volume":"94","author":"Williams","year":"2016","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.jad.2026.122644_bb0400","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1192\/bjp.133.5.429","article-title":"A rating scale for mania: reliability, validity and sensitivity","volume":"133","author":"Young","year":"1978","journal-title":"Br. J. Psychiatry"},{"issue":"7","key":"10.1016\/j.jad.2026.122644_bb0405","doi-asserted-by":"crossref","first-page":"2147","DOI":"10.1002\/hbm.25356","article-title":"Alterations in hippocampal subfield and amygdala subregion volumes in posttraumatic subjects with and without posttraumatic stress disorder","volume":"42","author":"Zhang","year":"2021","journal-title":"Hum. Brain Mapp."},{"issue":"8","key":"10.1016\/j.jad.2026.122644_bb0410","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1038\/s41386-020-0687-y","article-title":"Brain structural correlates of familial risk for mental illness: a meta-analysis of voxel-based morphometry studies in relatives of patients with psychotic or mood disorders","volume":"45","author":"Zhang","year":"2020","journal-title":"Neuropsychopharmacology"}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032726014989?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032726014989?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T16:48:26Z","timestamp":1792774106000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165032726014989"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,1]]},"references-count":82,"alternative-id":["S0165032726014989"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2026.122644","relation":{},"ISSN":["0165-0327"],"issn-type":[{"value":"0165-0327","type":"print"}],"subject":[],"published":{"date-parts":[[2027,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Aberrant amygdala subregion volumes in youth at high risk for bipolar disorder predict antidepressant-induced adverse events","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2026.122644","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"122644"}}