{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T02:08:50Z","timestamp":1778810930312,"version":"3.51.4"},"reference-count":37,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Ministry of Science, ICT, and Future Planning, Republic of Korea","award":["NRF-2014M3C7A1046042"],"award-info":[{"award-number":["NRF-2014M3C7A1046042"]}]},{"name":"Korea Healthcare Technology R & D Project, Ministry of Health, Welfare and Family Affairs, Republic of Korea","award":["A092145"],"award-info":[{"award-number":["A092145"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The American Journal of Geriatric Psychiatry"],"published-print":{"date-parts":[[2016,8]]},"DOI":"10.1016\/j.jagp.2016.03.001","type":"journal-article","created":{"date-parts":[[2016,3,11]],"date-time":"2016-03-11T12:45:17Z","timestamp":1457700317000},"page":"604-612","source":"Crossref","is-referenced-by-count":23,"title":["Association Between Serum Triglycerides and Cerebral Amyloidosis in Cognitively Normal Elderly"],"prefix":"10.1016","volume":"24","author":[{"given":"Hyo Jung","family":"Choi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min Soo","family":"Byun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dahyun","family":"Yi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Min","family":"Choe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo Kyung","family":"Sohn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hye Won","family":"Baek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun Ho","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyun Jung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji Young","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eun Jin","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu Kyeong","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jong Inn","family":"Woo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong Young","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jagp.2016.03.001_bib0010","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/S0140-6736(06)69113-7","article-title":"Alzheimer's disease","volume":"368","author":"Blennow","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.jagp.2016.03.001_bib0015","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/0165-6147(91)90609-V","article-title":"Amyloid deposition as the central event in the aetiology of Alzheimer's disease","volume":"12","author":"Hardy","year":"1991","journal-title":"Trends Pharmacol Sci"},{"key":"10.1016\/j.jagp.2016.03.001_bib0020","doi-asserted-by":"crossref","first-page":"92","DOI":"10.4103\/1673-5374.125335","article-title":"Lipid rafts participate in aberrant degradative autophagic-lysosomal pathway of amyloid-beta peptide in Alzheimer's disease","volume":"9","author":"Zhou","year":"2014","journal-title":"Neural Regen Res"},{"key":"10.1016\/j.jagp.2016.03.001_bib0025","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1111\/acel.12206","article-title":"Up-regulation of beta-amyloidogenesis in neuron-like human cells by both 24- and 27-hydroxycholesterol: protective effect of N-acetyl-cysteine","volume":"13","author":"Gamba","year":"2014","journal-title":"Aging Cell"},{"key":"10.1016\/j.jagp.2016.03.001_bib0030","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1001\/jamaneurol.2013.5390","article-title":"Associations between serum cholesterol levels and cerebral amyloidosis","volume":"71","author":"Reed","year":"2014","journal-title":"JAMA Neurol"},{"key":"10.1016\/j.jagp.2016.03.001_bib0035","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1016\/j.neurobiolaging.2013.09.040","article-title":"Markers of cholesterol transport are associated with amyloid deposition in the brain","volume":"35","author":"Hughes","year":"2014","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.jagp.2016.03.001_bib0040","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.1016\/j.neurobiolaging.2011.10.002","article-title":"Coronary risk correlates with cerebral amyloid deposition","volume":"33","author":"Reed","year":"2012","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.jagp.2016.03.001_bib0045","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.jalz.2011.08.008","article-title":"Cardiovascular risk factors, cortisol, and amyloid-beta deposition in Alzheimer's Disease Neuroimaging Initiative","volume":"8","author":"Toledo","year":"2012","journal-title":"Alzheimers Dement"},{"key":"10.1016\/j.jagp.2016.03.001_bib0050","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.nbd.2006.06.007","article-title":"Elevated plasma triglyceride levels precede amyloid deposition in Alzheimer's disease mouse models with abundant A beta in plasma","volume":"24","author":"Burgess","year":"2006","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.jagp.2016.03.001_bib0055","doi-asserted-by":"crossref","first-page":"77sr71","DOI":"10.1126\/scitranslmed.3002369","article-title":"Alzheimer's disease: the challenge of the second century","volume":"3","author":"Holtzman","year":"2011","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.jagp.2016.03.001_bib0060","doi-asserted-by":"crossref","first-page":"2837","DOI":"10.1093\/brain\/awm238","article-title":"Beta-amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease","volume":"130","author":"Pike","year":"2007","journal-title":"Brain"},{"key":"10.1016\/j.jagp.2016.03.001_bib0065","doi-asserted-by":"crossref","first-page":"1718","DOI":"10.1212\/01.wnl.0000261919.22630.ea","article-title":"Imaging beta-amyloid burden in aging and dementia","volume":"68","author":"Rowe","year":"2007","journal-title":"Neurology"},{"key":"10.1016\/j.jagp.2016.03.001_bib0070","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.jalz.2011.03.003","article-title":"Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease","volume":"7","author":"Sperling","year":"2011","journal-title":"Alzheimers Dement"},{"key":"10.1016\/j.jagp.2016.03.001_bib0075","doi-asserted-by":"crossref","first-page":"P47","DOI":"10.1093\/geronb\/57.1.P47","article-title":"Development of the Korean version of the Consortium to Establish a Registry for Alzheimer's Disease Assessment Packet (CERAD-K): clinical and neuropsychological assessment batteries","volume":"57","author":"Lee","year":"2002","journal-title":"J Gerontol B Psychol Sci Soc Sci"},{"key":"10.1016\/j.jagp.2016.03.001_bib0080","doi-asserted-by":"crossref","first-page":"2412","DOI":"10.1212\/WNL.43.11.2412-a","article-title":"The Clinical Dementia Rating (CDR): current version and scoring rules","volume":"43","author":"Morris","year":"1993","journal-title":"Neurology"},{"key":"10.1016\/j.jagp.2016.03.001_bib0085","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1017\/S1355617704101094","article-title":"A normative study of the CERAD neuropsychological assessment battery in the Korean elderly","volume":"10","author":"Lee","year":"2004","journal-title":"J Int Neuropsychol Soc"},{"key":"10.1016\/j.jagp.2016.03.001_bib0090","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1002\/gps.2027","article-title":"Normative study of the Stroop Color and Word Test in an educationally diverse elderly population","volume":"23","author":"Seo","year":"2008","journal-title":"Int J Geriatr Psychiatry"},{"key":"10.1016\/j.jagp.2016.03.001_bib0095","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1097\/JGP.0b013e3181cab764","article-title":"Total scores of the CERAD neuropsychological assessment battery: validation for mild cognitive impairment and dementia patients with diverse etiologies","volume":"18","author":"Seo","year":"2010","journal-title":"Am J Geriatr Psychiatry"},{"key":"10.1016\/j.jagp.2016.03.001_bib0100","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1212\/WNL.39.9.1159","article-title":"The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part I. Clinical and neuropsychological assessment of Alzheimer's disease","volume":"39","author":"Morris","year":"1989","journal-title":"Neurology"},{"key":"10.1016\/j.jagp.2016.03.001_bib0105","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1212\/01.WNL.0000130531.90205.EF","article-title":"Memory impairment, but not cerebrovascular disease, predicts progression of MCI to dementia","volume":"63","author":"DeCarli","year":"2004","journal-title":"Neurology"},{"key":"10.1016\/j.jagp.2016.03.001_bib0110","doi-asserted-by":"crossref","first-page":"351","DOI":"10.2214\/ajr.149.2.351","article-title":"MR signal abnormalities at 1.5 T in Alzheimer's dementia and normal aging","volume":"149","author":"Fazekas","year":"1987","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.jagp.2016.03.001_bib0115","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1097\/JGP.0b013e318202bf3a","article-title":"Relationship of amyloid-beta burden with age-at-onset in Alzheimer disease","volume":"19","author":"Choo","year":"2011","journal-title":"Am J Geriatr Psychiatry"},{"key":"10.1016\/j.jagp.2016.03.001_bib0120","first-page":"1959","article-title":"Simplified quantification of Pittsburgh Compound B amyloid imaging PET studies: a comparative analysis","volume":"46","author":"Lopresti","year":"2005","journal-title":"J Nucl Med"},{"key":"10.1016\/j.jagp.2016.03.001_bib0125","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1006\/nimg.2001.0978","article-title":"Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain","volume":"15","author":"Tzourio-Mazoyer","year":"2002","journal-title":"Neuroimage"},{"key":"10.1016\/j.jagp.2016.03.001_bib0130","doi-asserted-by":"crossref","first-page":"6820","DOI":"10.1073\/pnas.0900345106","article-title":"Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease","volume":"106","author":"Reiman","year":"2009","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jagp.2016.03.001_bib0135","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1039\/b700706j","article-title":"The physiological and molecular regulation of lipoprotein assembly and secretion","volume":"3","author":"Blasiole","year":"2007","journal-title":"Mol Biosyst"},{"key":"10.1016\/j.jagp.2016.03.001_bib0140","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.tem.2013.04.001","article-title":"The regulation of ApoB metabolism by insulin","volume":"24","author":"Haas","year":"2013","journal-title":"Trends Endocrinol Metab"},{"key":"10.1016\/j.jagp.2016.03.001_bib0145","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.atherosclerosissup.2008.05.010","article-title":"Chylomicron amyloid-beta in the aetiology of Alzheimer's disease","volume":"9","author":"Takechi","year":"2008","journal-title":"Atheroscler Suppl"},{"key":"10.1016\/j.jagp.2016.03.001_bib0150","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/0304-3940(92)90531-B","article-title":"Apolipoprotein B immunoreactivity in senile plaque and vascular amyloids and neurofibrillary tangles in the brains of patients with Alzheimer's disease","volume":"134","author":"Namba","year":"1992","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.jagp.2016.03.001_bib0155","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1007\/s00418-009-0567-3","article-title":"Three-dimensional colocalization analysis of plasma-derived apolipoprotein B with amyloid plaques in APP\/PS1 transgenic mice","volume":"131","author":"Takechi","year":"2009","journal-title":"Histochem Cell Biol"},{"key":"10.1016\/j.jagp.2016.03.001_bib0160","doi-asserted-by":"crossref","first-page":"32916","DOI":"10.1074\/jbc.271.51.32916","article-title":"Amyloid beta-peptide is transported on lipoproteins and albumin in human plasma","volume":"271","author":"Biere","year":"1996","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jagp.2016.03.001_bib0165","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1258\/acb.2008.007214","article-title":"Plasma lipoprotein beta-amyloid in subjects with Alzheimer's disease or mild cognitive impairment","volume":"45","author":"Mamo","year":"2008","journal-title":"Ann Clin Biochem"},{"key":"10.1016\/j.jagp.2016.03.001_bib0170","doi-asserted-by":"crossref","first-page":"E1736","DOI":"10.1152\/ajpendo.00122.2007","article-title":"PPARgamma regulates adipose triglyceride lipase in adipocytes in vitro and in vivo","volume":"293","author":"Kershaw","year":"2007","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.jagp.2016.03.001_bib0175","doi-asserted-by":"crossref","first-page":"10117","DOI":"10.1523\/JNEUROSCI.5268-11.2012","article-title":"Mechanisms underlying the rapid peroxisome proliferator-activated receptor-gamma-mediated amyloid clearance and reversal of cognitive deficits in a murine model of Alzheimer's disease","volume":"32","author":"Mandrekar-Colucci","year":"2012","journal-title":"J Neurosci"},{"key":"10.1016\/j.jagp.2016.03.001_bib0180","doi-asserted-by":"crossref","first-page":"17321","DOI":"10.1523\/JNEUROSCI.1569-12.2012","article-title":"PPARgamma\/RXRalpha-induced and CD36-mediated microglial amyloid-beta phagocytosis results in cognitive improvement in amyloid precursor protein\/presenilin 1 mice","volume":"32","author":"Yamanaka","year":"2012","journal-title":"J Neurosci"},{"key":"10.1016\/j.jagp.2016.03.001_bib0185","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1212\/WNL.0b013e3181d6476a","article-title":"Randomized controlled trial of atorvastatin in mild to moderate Alzheimer disease: LEADe","volume":"74","author":"Feldman","year":"2010","journal-title":"Neurology"},{"key":"10.1016\/j.jagp.2016.03.001_bib0190","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1016\/S0140-6736(02)11600-X","article-title":"Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial","volume":"360","author":"Shepherd","year":"2002","journal-title":"Lancet"}],"container-title":["The American Journal of Geriatric Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1064748116300422?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1064748116300422?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,14]],"date-time":"2018-09-14T07:00:15Z","timestamp":1536908415000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1064748116300422"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8]]},"references-count":37,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2016,8]]}},"alternative-id":["S1064748116300422"],"URL":"https:\/\/doi.org\/10.1016\/j.jagp.2016.03.001","relation":{},"ISSN":["1064-7481"],"issn-type":[{"value":"1064-7481","type":"print"}],"subject":[],"published":{"date-parts":[[2016,8]]}}}