{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T17:14:40Z","timestamp":1778519680408,"version":"3.51.4"},"reference-count":34,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100014593","name":"Neurocrine Biosciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["1R01MH093321-01A1"],"award-info":[{"award-number":["1R01MH093321-01A1"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["U01 MH068846"],"award-info":[{"award-number":["U01 MH068846"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["RES512188"],"award-info":[{"award-number":["RES512188"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["3R01MH103318"],"award-info":[{"award-number":["3R01MH103318"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100002296","name":"Reuter Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002296","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001308","name":"Reinberger Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001308","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007880","name":"Johns Hopkins University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007880","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009155","name":"Otsuka America Pharmaceutical","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009155","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005565","name":"Janssen Biotech","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005565","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100002411","name":"Woodruff Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002411","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ajgponline.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Geriatric Psychiatry"],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1016\/j.jagp.2019.04.003","type":"journal-article","created":{"date-parts":[[2019,4,18]],"date-time":"2019-04-18T19:18:40Z","timestamp":1555615120000},"page":"1122-1134","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Understanding Aging in Bipolar Disorder by Integrating Archival Clinical Research Datasets"],"prefix":"10.1016","volume":"27","author":[{"given":"Lisa T.","family":"Eyler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle E.","family":"Aebi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca E.","family":"Daly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristen","family":"Hansen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Curtis","family":"Tatsuoka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert C.","family":"Young","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martha","family":"Sajatovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jagp.2019.04.003_bib0001","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1176\/appi.ps.55.9.1014","article-title":"Age-related modifiers of clinical presentation and health service use among veterans with bipolar disorder","volume":"55","author":"Sajatovic","year":"2004","journal-title":"Psychiatr Serv"},{"key":"10.1016\/j.jagp.2019.04.003_bib0002","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1111\/bdi.12331","article-title":"A report on older-age bipolar disorder from the International Society for Bipolar Disorders Task Force","volume":"17","author":"Sajatovic","year":"2015","journal-title":"Bipolar Disord"},{"key":"10.1016\/j.jagp.2019.04.003_bib0003","first-page":"79","article-title":"A 6-month, prospective, randomized controlled trial of customized adherence enhancement versus bipolar-specific educational control in poorly adherent individuals with bipolar disorder","author":"Sajatovic","year":"2018","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.jagp.2019.04.003_bib0004","series-title":"Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Patient Edition (SCID-I\/P)","author":"First","year":"2002"},{"key":"10.1016\/j.jagp.2019.04.003_bib0005","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1111\/bdi.12326","article-title":"Symptom severity, self-reported adherence, and electronic pill monitoring in poorly adherent patients with bipolar disorder","volume":"17","author":"Sajatovic","year":"2015","journal-title":"Bipolar Disord"},{"key":"10.1016\/j.jagp.2019.04.003_bib0006","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1176\/appi.ajp.2017.15050657","article-title":"GERI-BD: a randomized double-blind controlled trial of lithium and divalproex in the treatment of mania in older patients with bipolar disorder","volume":"174","author":"Young","year":"2017","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.jagp.2019.04.003_bib0007","series-title":"Diagnostic and Statistical Manual DSM-IV-TR","year":"1994"},{"key":"10.1016\/j.jagp.2019.04.003_bib0008","series-title":"Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Patient Edition (SCID-I\/P)","author":"First","year":"2002"},{"key":"10.1016\/j.jagp.2019.04.003_bib0009","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1192\/bjp.133.5.429","article-title":"A rating scale for mania: reliability, validity, and sensitivity","volume":"133","author":"Young","year":"1978","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.jagp.2019.04.003_bib0010","doi-asserted-by":"crossref","first-page":"799","DOI":"10.2466\/pr0.1962.10.3.799","article-title":"The brief psychiatric rating scale","volume":"10","author":"Overall","year":"1962","journal-title":"Psychol Rep"},{"key":"10.1016\/j.jagp.2019.04.003_bib0011","series-title":"Multiaxial assessment, in DSM-IV-TR: Diagnostic and Statistical Manual of Mental Disorders","year":"2002"},{"key":"10.1016\/j.jagp.2019.04.003_bib0012","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1136\/jnnp.23.1.56","article-title":"A rating scale for depression","volume":"23","author":"Hamilton","year":"1960","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.jagp.2019.04.003_bib0013","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1192\/bjp.134.4.382","article-title":"A new depression scale designed to be sensitive to change","volume":"134","author":"Montgomery","year":"1979","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.jagp.2019.04.003_bib0014","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1097\/01.mlr.0000163658.65008.ec","article-title":"Use of a self-report-generated Charlson Comorbidity Index for predicting mortality","volume":"43","author":"Chaudhry","year":"2005","journal-title":"Med Care"},{"key":"10.1016\/j.jagp.2019.04.003_bib0015","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1111\/j.1532-5415.1968.tb02103.x","article-title":"Cumulative illness rating scale","volume":"16","author":"Linn","year":"1968","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.jagp.2019.04.003_bib0016","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/0165-1781(92)90005-N","article-title":"Rating chronic medical illness burden in geropsychiatric practice and research: application of the Cumulative Illness Rating Scale","volume":"41","author":"Miller","year":"1992","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.jagp.2019.04.003_bib0017","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.jad.2013.04.028","article-title":"Severity classification on the Hamilton Depression Rating Scale","volume":"150","author":"Zimmerman","year":"2013","journal-title":"J Affect Disord"},{"key":"10.1016\/j.jagp.2019.04.003_bib0018","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.jad.2016.12.041","article-title":"What does the MADRS mean? Equipercentile linking with the CGI using a company database of mirtazapine studies","volume":"210","author":"Leucht","year":"2017","journal-title":"J Affect Disord"},{"key":"10.1016\/j.jagp.2019.04.003_bib0019","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.jad.2017.09.042","article-title":"Translating the HAM-D into the MADRS and vice versa with equipercentile linking","volume":"226","author":"Leucht","year":"2018","journal-title":"J Affect Disord"},{"key":"10.1016\/j.jagp.2019.04.003_bib0020","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.acn.2004.03.010","article-title":"Detecting depression in Alzheimer's disease: evaluation of four different scales","volume":"20","author":"Muller-Thomsen","year":"2005","journal-title":"Arch Clin Neuropsychol"},{"key":"10.1016\/j.jagp.2019.04.003_bib0021","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1161\/01.STR.29.3.618","article-title":"The Sunnybrook Stroke Study: a prospective study of depressive symptoms and functional outcome","volume":"29","author":"Herrmann","year":"1998","journal-title":"Stroke"},{"key":"10.1016\/j.jagp.2019.04.003_bib0022","series-title":"Montgomery-Asberg Depression Rating Scale (MADRS) Biopsychosocial Assessment Tools for the Elderly-Assessment Summary Sheet in Measuring Health: A Guide to Rating Scales and Questionnaires","author":"McDowell","year":"2006"},{"key":"10.1016\/j.jagp.2019.04.003_bib0023","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1177\/0891988712436683","article-title":"Medical and psychiatric comorbidities among elderly individuals with bipolar disorder: a literature review","volume":"25","author":"Lala","year":"2012","journal-title":"J Geriatr Psychiatry Neurol"},{"key":"10.1016\/j.jagp.2019.04.003_bib0024","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1097\/JGP.0b013e3181b7ef2a","article-title":"Cognitive dysfunction and medical morbidity in elderly outpatients with bipolar disorder","volume":"17","author":"Tsai","year":"2009","journal-title":"Am J Geriatr Psychiatry"},{"key":"10.1016\/j.jagp.2019.04.003_bib0025","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1111\/j.1399-5618.2009.00735.x","article-title":"Cardiovascular disease and hypertension among adults with bipolar I disorder in the United States","volume":"11","author":"Goldstein","year":"2009","journal-title":"Bipolar Disord"},{"key":"10.1016\/j.jagp.2019.04.003_bib0026","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1007\/s00246-014-0980-9","article-title":"Non-invasive vascular imaging is associated with cardiovascular risk factors among adolescents with bipolar disorder","volume":"36","author":"Hatch","year":"2015","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.jagp.2019.04.003_bib0027","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1007\/s40263-016-0368-x","article-title":"Medication adherence in patients with bipolar disorder: a comprehensive review","volume":"30","author":"Levin","year":"2016","journal-title":"CNS Drugs"},{"key":"10.1016\/j.jagp.2019.04.003_bib0028","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.jad.2016.11.021","article-title":"The difficult lives of individuals with bipolar disorder: a review of functional outcomes and their implications for treatment","volume":"209","author":"Gitlin","year":"2017","journal-title":"J Affect Disord"},{"key":"10.1016\/j.jagp.2019.04.003_bib0029","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/S0165-0327(02)00004-6","article-title":"Increased risk of developing dementia in patients with major affective disorders compared to patients with other medical illnesses","volume":"73","author":"Kessing","year":"2003","journal-title":"J Affect Disord"},{"key":"10.1016\/j.jagp.2019.04.003_bib0030","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1111\/j.1600-0447.1999.tb10843.x","article-title":"Dementia in affective disorder: a case-register study","volume":"100","author":"Kessing","year":"1999","journal-title":"Acta Psychiatr Scand"},{"key":"10.1016\/j.jagp.2019.04.003_bib0031","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1136\/jnnp.2003.031773","article-title":"Does the risk of developing dementia increase with the number of episodes in patients with depressive disorder and in patients with bipolar disorder?","volume":"75","author":"Kessing","year":"2004","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.jagp.2019.04.003_bib0032","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1212\/WNL.41.9.1393","article-title":"Clinical risk factors for Alzheimer's disease: a population-based case-control study","volume":"41","author":"Kokmen","year":"1991","journal-title":"Neurology"},{"key":"10.1016\/j.jagp.2019.04.003_bib0033","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.dcn.2018.04.003","article-title":"A description of the ABCD organizational structure and communication framework","volume":"32","author":"Auchter","year":"2018","journal-title":"Developmental Cognitive Neuroscience"},{"key":"10.1016\/j.jagp.2019.04.003_bib0034","unstructured":"Sajatovic M, Eyler LT, Rej S, et al: The Global Aging and Geriatric Experiments in Bipolar Disorders Database (GAGE-BD) project: Understanding older-age bipolar disorder by combining multiple datasets, Bipolar Disorders, in press"}],"container-title":["The American Journal of Geriatric Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1064748119303367?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1064748119303367?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T17:04:08Z","timestamp":1778519048000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1064748119303367"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10]]},"references-count":34,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["S1064748119303367"],"URL":"https:\/\/doi.org\/10.1016\/j.jagp.2019.04.003","relation":{},"ISSN":["1064-7481"],"issn-type":[{"value":"1064-7481","type":"print"}],"subject":[],"published":{"date-parts":[[2019,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Understanding Aging in Bipolar Disorder by Integrating Archival Clinical Research Datasets","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Geriatric Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jagp.2019.04.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 American Association for Geriatric Psychiatry. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}