{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T23:01:20Z","timestamp":1791673280925,"version":"4.3.4"},"reference-count":48,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ajgponline.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Geriatric Psychiatry"],"published-print":{"date-parts":[[2020,1]]},"DOI":"10.1016\/j.jagp.2019.08.006","type":"journal-article","created":{"date-parts":[[2019,8,9]],"date-time":"2019-08-09T02:04:03Z","timestamp":1565316243000},"page":"48-60","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":120,"title":["The Interplay Between Post-traumatic Stress Disorder and Dementia: A Systematic Review"],"prefix":"10.1016","volume":"28","author":[{"given":"Philippe","family":"Desmarais","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle","family":"Weidman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9anne","family":"Wassef","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Andr\u00e9e","family":"Bruneau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jess","family":"Friedland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulina","family":"Bajsarowicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Pierre","family":"Thibodeau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan","family":"Herrmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quoc Dinh","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jagp.2019.08.006_bib0001","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1192\/bjp.bp.108.049619","article-title":"Prevalence, correlates and course of behavioural and psychological symptoms of dementia in the population","volume":"194","author":"Savva","year":"2009","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.jagp.2019.08.006_bib0002","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1017\/S1041610217001260","article-title":"Social inappropriateness in neurodegenerative disorders","volume":"30","author":"Desmarais","year":"2018","journal-title":"Int Psychogeriatr"},{"key":"10.1016\/j.jagp.2019.08.006_bib0003","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1001\/jama.288.12.1475","article-title":"Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment \u2013 Results from the Cardiovascular Health Study","volume":"288","author":"Lyketsos","year":"2002","journal-title":"JAMA"},{"key":"10.1016\/j.jagp.2019.08.006_bib0004","doi-asserted-by":"crossref","first-page":"227","DOI":"10.3233\/JAD-170632","article-title":"Risk of conversion to dementia in a mild behavioral impairment group compared to a psychiatric group and to a mild cognitive impairment group","volume":"62","author":"Taragano","year":"2018","journal-title":"J Alzheimers Dis"},{"key":"10.1016\/j.jagp.2019.08.006_bib0005","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1001\/archpsyc.1995.03950240066012","article-title":"Posttraumatic-stress-disorder in the national comorbidity survey","volume":"52","author":"Kessler","year":"1995","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.jagp.2019.08.006_bib0006","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1037\/0022-006X.61.6.984","article-title":"Prevalence of civilian trauma and posttraumatic stress disorder in a representative national sample of women","volume":"61","author":"Resnick","year":"1993","journal-title":"J Consult Clin Psycholo"},{"key":"10.1016\/j.jagp.2019.08.006_bib0007","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1037\/0894-4105.16.1.5","article-title":"Attention, learning, and memory performances and intellectual resources in Vietnam veterans: PTSD and no disorder comparisons","volume":"16","author":"Vasterling","year":"2002","journal-title":"Neuropsychology"},{"key":"10.1016\/j.jagp.2019.08.006_bib0008","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/BF00964322","article-title":"Memory and attention in combat-related posttraumatic-stress-disorder (PTSD)","volume":"15","author":"Uddo","year":"1993","journal-title":"J Psychopathol Behav Assess"},{"key":"10.1016\/j.jagp.2019.08.006_bib0009","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1001\/archgenpsychiatry.2010.61","article-title":"Post-traumatic stress disorder and risk of dementia among US veterans","volume":"67","author":"Yaffe","year":"2010","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.jagp.2019.08.006_bib0010","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1111\/j.1532-5415.2010.02977.x","article-title":"Greater prevalence and incidence of dementia in older veterans with posttraumatic stress disorder","volume":"58","author":"Qureshi","year":"2010","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.jagp.2019.08.006_bib0011","doi-asserted-by":"crossref","first-page":"203","DOI":"10.3233\/JAD-171134","article-title":"Post-traumatic stress disorder heralding the onset of semantic frontotemporal dementia","volume":"63","author":"Bonanni","year":"2018","journal-title":"J Alzheimers Dis"},{"key":"10.1016\/j.jagp.2019.08.006_bib0012","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.jalz.2017.04.014","article-title":"Post-traumatic stress disorder and risk of dementia among members of a health care delivery system","volume":"14","author":"Flatt","year":"2018","journal-title":"Alzheimers Dement"},{"key":"10.1016\/j.jagp.2019.08.006_bib0013","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1177\/089198870101400105","article-title":"Worsening of post-traumatic stress disorder symptoms with cognitive decline: case series","volume":"14","author":"Mittal","year":"2001","journal-title":"J Geriatr Psychiatry Neurol"},{"key":"10.1016\/j.jagp.2019.08.006_bib0014","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1111\/j.1532-5415.2000.tb03032.x","article-title":"A series of cases of dementia presenting with PTSD symptoms in World War II combat veterans","volume":"48","author":"Johnston","year":"2000","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.jagp.2019.08.006_bib0015","doi-asserted-by":"crossref","first-page":"b2700","DOI":"10.1136\/bmj.b2700","article-title":"The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration","volume":"339","author":"Liberati","year":"2009","journal-title":"BMJ"},{"key":"10.1016\/j.jagp.2019.08.006_bib0016","series-title":"IBM SPSS Statistics for Windows, Version 24.0","year":"2016"},{"key":"10.1016\/j.jagp.2019.08.006_bib0017","unstructured":"Wells G, Shea B, O'Connell D, et al. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. Available at: http:\/\/www.ohri.ca\/programs\/clinical_epidemiology\/oxford.asp"},{"key":"10.1016\/j.jagp.2019.08.006_bib0018","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.jagp.2018.02.007","article-title":"When post-traumatic stress disorder and Charles Bonnet syndrome become Lewy body dementia","volume":"26","author":"Ahearn","year":"2018","journal-title":"Am J Geriatr Psychiatry"},{"key":"10.1016\/j.jagp.2019.08.006_bib0019","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.jagp.2018.01.181","article-title":"New onset post-traumatic stress disorder in long-term car home residents with a pre-existing diagnosis of a major neurocognitive disorder","volume":"26","author":"Lachmann","year":"2018","journal-title":"Am J Geriatr Psychiatry"},{"key":"10.1016\/j.jagp.2019.08.006_bib0020","first-page":"776","article-title":"Post-traumatic stress disorder secondary to Alzheimer's disease: emergence of an underlying pathology in the oldest old","volume":"175","author":"Monfort","year":"2017","journal-title":"Ann M\u00e9d-Psychol"},{"key":"10.1016\/j.jagp.2019.08.006_bib0021","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/j.jagp.2017.03.012","article-title":"Post-traumatic stress disorder and risk of Parkinson disease: nationwide longitudinal study","volume":"25","author":"Chan","year":"2017","journal-title":"Am J Geriatr Psychiatry"},{"key":"10.1016\/j.jagp.2019.08.006_bib0022","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1002\/pnp.477","article-title":"Delayed-onset post-traumatic stress disorder symptoms in dementia","volume":"21","author":"Martinez-Clavera","year":"2017","journal-title":"Prog Neurol Psychiatry"},{"key":"10.1016\/j.jagp.2019.08.006_bib0023","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1111\/jgs.14837","article-title":"Posttraumatic stress disorder, antipsychotic use and risk of dementia in veterans","volume":"65","author":"Roughead","year":"2017","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.jagp.2019.08.006_bib0024","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1111\/jgs.14756","article-title":"PTSD, psychotropic medication use, and the risk of dementia among US veterans: a retrospective cohort study","volume":"65","author":"Mawanda","year":"2017","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.jagp.2019.08.006_bib0025","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.jad.2016.08.013","article-title":"Risk of developing dementia among patients with posttraumatic stress disorder: a nationwide longitudinal study","volume":"205","author":"Wang","year":"2016","journal-title":"J Affect Disord"},{"key":"10.1016\/j.jagp.2019.08.006_bib0026","doi-asserted-by":"crossref","first-page":"S236","DOI":"10.1016\/j.jalz.2014.04.004","article-title":"Prisoner of war status, posttraumatic stress disorder, and dementia in older veterans","volume":"10","author":"Meziab","year":"2014","journal-title":"Alzheimers Dement"},{"key":"10.1016\/j.jagp.2019.08.006_bib0027","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.amjopharm.2012.03.001","article-title":"Case report: post-traumatic memories triggered by donepezil in a dose-dependent pattern","volume":"10","author":"Wolff","year":"2012","journal-title":"Am J Geriatr Pharmacother"},{"key":"10.1016\/j.jagp.2019.08.006_bib0028","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1111\/j.1532-5415.2011.03344.x","article-title":"Trauma reenactments in aging veterans with dementia","volume":"59","author":"Dallam","year":"2011","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.jagp.2019.08.006_bib0029","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1097\/NMD.0b013e31820c71e0","article-title":"Posttraumatic stress disorder and dementia in Holocaust survivors","volume":"199","author":"Sperling","year":"2011","journal-title":"J Nerv Ment Dis"},{"key":"10.1016\/j.jagp.2019.08.006_bib0030","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1002\/gps.2258","article-title":"Post-traumatic stress disorder and prediction of aggression in persons with dementia","volume":"24","author":"Ball","year":"2009","journal-title":"Int J Geriatr Psychiatry"},{"key":"10.1016\/j.jagp.2019.08.006_bib0031","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1176\/jnp.2007.19.1.92","article-title":"Posttraumatic stress disorder-like symptoms after treatment with acetylcholinesterase inhibitors","volume":"19","author":"McLay","year":"2007","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"10.1016\/j.jagp.2019.08.006_bib0032","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1097\/00019442-200505000-00013","article-title":"Delayed onset of posttraumatic stress disorder among male combat veterans: a case series","volume":"13","author":"Ruzich","year":"2005","journal-title":"Am J Geriatr Psychiatry"},{"key":"10.1016\/j.jagp.2019.08.006_bib0033","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1002\/gps.333","article-title":"Contribution of PTSD\/POW history to behavioral disturbances in dementia","volume":"16","author":"Verma","year":"2001","journal-title":"Int J Geriatr Psychiatry"},{"key":"10.1016\/j.jagp.2019.08.006_bib0034","doi-asserted-by":"crossref","first-page":"206","DOI":"10.4088\/JCP.v62n0312c","article-title":"Emergence of PTSD in trauma survivors with dementia","volume":"62","author":"van Achterberg","year":"2001","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.jagp.2019.08.006_bib0035","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1023\/A:1024449517730","article-title":"Persistence of combat-related posttraumatic stress symptoms for 75 years","volume":"11","author":"Hamilton","year":"1998","journal-title":"J Trauma Stress"},{"key":"10.1016\/j.jagp.2019.08.006_bib0036","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1111\/j.1532-5415.1997.tb00982.x","article-title":"Sexual violence, post-traumatic stress disorder and dementia","volume":"45","author":"McCartney","year":"1997","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.jagp.2019.08.006_bib0037","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1016\/j.biopsych.2007.04.027","article-title":"Twenty-four hour plasma cortisol and adrenocorticotrophic hormone in Gulf war veterans: relationships to posttraumatic stress disorder and health symptoms","volume":"62","author":"Golier","year":"2007","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.jagp.2019.08.006_bib0038","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1176\/ajp.156.4.585","article-title":"Serial CSF corticotropin-releasing hormone levels and adrenocortical activity in combat veterans in posttraumatic stress disorder","volume":"156","author":"Baker","year":"1999","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.jagp.2019.08.006_bib0039","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1192\/bjp.bp.106.024877","article-title":"Cortisol and post-traumatic stress disorder in adults: systematic review and meta-analysis","volume":"191","author":"Meewisse","year":"2007","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.jagp.2019.08.006_bib0040","doi-asserted-by":"crossref","first-page":"311","DOI":"10.3109\/10253890.2012.721824","article-title":"Delayed memory effects after intense stress in Special Forces candidates: exploring path processes between cortisol secretion and memory recall","volume":"16","author":"Taverniers","year":"2013","journal-title":"Stress"},{"key":"10.1016\/j.jagp.2019.08.006_bib0041","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1001\/archpsyc.56.6.527","article-title":"Decreased memory performance in healthy humans induced by stress-level cortisol treatment","volume":"56","author":"Newcomer","year":"1999","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.jagp.2019.08.006_bib0042","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1038\/271","article-title":"Cortisol levels during human aging predict hippocampal atrophy and memory deficits","volume":"1","author":"Lupien","year":"1998","journal-title":"Nat Neurosci"},{"issue":"Suppl 1","key":"10.1016\/j.jagp.2019.08.006_bib0043","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.neurobiolaging.2005.09.037","article-title":"Urinary cortisol excretion as a predictor of incidence cognitive impairment","volume":"26","author":"Karlamangla","year":"2005","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.jagp.2019.08.006_bib0044","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1002\/hipo.20102","article-title":"Bilateral hippocampal volume reduction in adults with post-traumatic stress disorder: a meta-analysis of structural MRI studies","volume":"15","author":"Smith","year":"2005","journal-title":"Hippocampus"},{"key":"10.1016\/j.jagp.2019.08.006_bib0045","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1176\/ajp.152.7.973","article-title":"MRI-based measurement of hippocampal volume in patients with combat-related posttraumatic stress disorder","volume":"152","author":"Bremner","year":"1995","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.jagp.2019.08.006_bib0046","first-page":"41","article-title":"Alzheimer's dementia and post-traumatic stress disorder differences and similarities in neuroimaging","volume":"12","author":"Tsolaki","year":"2009","journal-title":"Hell J Nucl Med"},{"key":"10.1016\/j.jagp.2019.08.006_bib0047","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.bbi.2015.08.015","article-title":"Chronic restraint stress triggers dopaminergic and noradrenergic neurodegeneration: possible role of chronic stress in the onset of Parkinson's disease","volume":"51","author":"Sugama","year":"2016","journal-title":"Brain Behav Immun"},{"key":"10.1016\/j.jagp.2019.08.006_bib0048","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/j.neurobiolaging.2014.10.031","article-title":"Cerebrospinal fluid cortisol and clinical disease progression in MCI and dementia of Alzheimer's type","volume":"36","author":"Popp","year":"2015","journal-title":"Neurobiol Aging"}],"container-title":["The American Journal of Geriatric Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1064748119304695?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1064748119304695?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T04:28:54Z","timestamp":1761020934000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1064748119304695"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":48,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["S1064748119304695"],"URL":"https:\/\/doi.org\/10.1016\/j.jagp.2019.08.006","relation":{},"ISSN":["1064-7481"],"issn-type":[{"value":"1064-7481","type":"print"}],"subject":[],"published":{"date-parts":[[2020,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Interplay Between Post-traumatic Stress Disorder and Dementia: A Systematic Review","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Geriatric Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jagp.2019.08.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 American Association for Geriatric Psychiatry. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}