{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T23:15:42Z","timestamp":1792192542440,"version":"4.4.0"},"reference-count":34,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,11,10]],"date-time":"2020-11-10T00:00:00Z","timestamp":1604966400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000764","name":"King's College London","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000764","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MR\/R016372\/1"],"award-info":[{"award-number":["MR\/R016372\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000272","name":"National Institute for Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["116074"],"award-info":[{"award-number":["116074"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009362","name":"South London and Maudsley NHS Foundation Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009362","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000274","name":"British Heart Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000274","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010756","name":"Health and Social Care Research and Development Division","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010756","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001626","name":"Public Health Agency","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001626","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008994","name":"European Society of Contraception and Reproductive Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008994","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000269","name":"Economic and Social Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000269","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ajgponline.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Geriatric Psychiatry"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1016\/j.jagp.2020.10.018","type":"journal-article","created":{"date-parts":[[2020,11,5]],"date-time":"2020-11-05T21:35:00Z","timestamp":1604612100000},"page":"604-616","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Cognitive Trajectories in Comorbid Dementia With Schizophrenia or Bipolar Disorder: The South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLaM BRC) Case Register"],"prefix":"10.1016","volume":"29","author":[{"given":"Rebecca","family":"Bendayan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurelie","family":"Mascio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Stewart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angus","family":"Roberts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard J.","family":"Dobson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jagp.2020.10.018_bib0001","doi-asserted-by":"crossref","first-page":"2753","DOI":"10.1017\/S0033291717001490","article-title":"Meta-analysis of longitudinal studies of cognition in bipolar disorder: comparison with healthy controls and schizophrenia","volume":"47","author":"Bora","year":"2017","journal-title":"Psychol Med"},{"key":"10.1016\/j.jagp.2020.10.018_bib0002","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.schres.2005.08.004","article-title":"Cognitive functioning in patients with schizophrenia and bipolar disorder: a quantitative review","volume":"80","author":"Krabbendam","year":"2005","journal-title":"Schizophr Res"},{"key":"10.1016\/j.jagp.2020.10.018_bib0003","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1192\/bjp.bp.108.055731","article-title":"Cognitive functioning in schizophrenia, schizoaffective disorder and affective psychoses: meta-analytic study","volume":"195","author":"Bora","year":"2009","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.jagp.2020.10.018_bib0004","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1093\/schbul\/sbr100","article-title":"How genes and environmental factors determine the different neurodevelopmental trajectories of schizophrenia and bipolar disorder","volume":"8","author":"Demjaha","year":"2012","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.jagp.2020.10.018_bib0005","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1017\/S0033291712001614","article-title":"Two-year course of cognitive function and instrumental activities of daily living in older adults with bipolar disorder: evidence for neuroprogression?","volume":"43","author":"Gildengers","year":"2013","journal-title":"Psychol Med"},{"key":"10.1016\/j.jagp.2020.10.018_bib0006","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/j.1399-5618.2012.01011.x","article-title":"Meta\u2010analysis of the association between cognitive abilities and everyday functioning in bipolar disorder","volume":"14","author":"Depp","year":"2012","journal-title":"Bipolar Disord"},{"key":"10.1016\/j.jagp.2020.10.018_bib0007","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0165-1781(01)00247-5","article-title":"Outpatients with schizophrenia and bipolar I disorder: do they differ in their cognitive and social functioning?","volume":"102","author":"Dickerson","year":"2001","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.jagp.2020.10.018_bib0008","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.jagp.2016.11.014","article-title":"History of bipolar disorder and the risk of dementia: a systematic review and meta-analysis","volume":"25","author":"Diniz","year":"2017","journal-title":"Am J Geriatr Psychiatry"},{"key":"10.1016\/j.jagp.2020.10.018_bib0009","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.2147\/NDT.S100843","article-title":"Clinical features, comorbidity, and cognitive impairment in elderly bipolar patients","volume":"12","author":"Rise","year":"2016","journal-title":"Neuropsychiatr Dis Treat"},{"key":"10.1016\/j.jagp.2020.10.018_bib0010","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1002\/mds.25003","article-title":"Psychosis in Parkinson's disease without dementia: common and comorbid with other non\u2010motor symptoms","volume":"7","author":"Lee","year":"2012","journal-title":"Mov Disord"},{"key":"10.1016\/j.jagp.2020.10.018_bib0011","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.pnpbp.2019.04.008","article-title":"A review on shared clinical and molecular mechanisms between bipolar disorder and frontotemporal dementia","volume":"93","author":"Nascimento","year":"2019","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.jagp.2020.10.018_bib0012","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1002\/da.20521","article-title":"The phenomenology of bipolar disorder: what drives the high rate of medical burden and determines long\u2010term prognosis?","volume":"26","author":"Soreca","year":"2009","journal-title":"Depress Anxiety"},{"key":"10.1016\/j.jagp.2020.10.018_bib0013","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/S0165-0327(02)00004-6","article-title":"Increased risk of developing dementia in patients with major affective disorders compared to patients with other medical illnesses","volume":"73","author":"Kessing","year":"2003","journal-title":"J Affect Disord"},{"key":"10.1016\/j.jagp.2020.10.018_bib0014","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/0022-3956(82)90038-3","article-title":"Schizophrenia: caused by a fault in programmed synaptic elimination during adolescence?","volume":"17","author":"Feinberg","year":"1982","journal-title":"J Psychiatr Res"},{"key":"10.1016\/j.jagp.2020.10.018_bib0015","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1002\/wps.20725","article-title":"The synaptic pruning hypothesis of schizophrenia: promises and challenges","volume":"19","author":"Keshavan","year":"2020","journal-title":"World Psychiatry"},{"key":"10.1016\/j.jagp.2020.10.018_bib0016","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1177\/0004867414529477","article-title":"Comparing neurocognition in severe chronic schizophrenia and frontotemporal dementia","volume":"48","author":"Chan","year":"2014","journal-title":"Aust N Z J Psychiatry"},{"key":"10.1016\/j.jagp.2020.10.018_bib0017","doi-asserted-by":"crossref","first-page":"168","DOI":"10.3109\/09540261.2013.765389","article-title":"Schizophrenia and frontotemporal dementia: Shared causation?","volume":"25","author":"Harciarek","year":"2013","journal-title":"Int Rev Psychiatry"},{"key":"10.1016\/j.jagp.2020.10.018_bib0018","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1159\/000238394","article-title":"Primary health care use and reasons for hospital admissions in dementia patients in France: database study for 2007","volume":"28","author":"Tuppin","year":"2009","journal-title":"Dement Geriatr Cogn Disord"},{"key":"10.1016\/j.jagp.2020.10.018_bib0019","doi-asserted-by":"crossref","first-page":"1556","DOI":"10.1001\/archneur.62.10.1556","article-title":"Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease","volume":"62","author":"Kivipelto","year":"2005","journal-title":"Arch Neurol"},{"key":"10.1016\/j.jagp.2020.10.018_bib0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-244X-9-51","article-title":"The South London and Maudsley NHS foundation trust biomedical research centre (SLAM BRC) case register: development and descriptive data","volume":"9","author":"Stewart","year":"2009","journal-title":"BMC Psychiatry"},{"key":"10.1016\/j.jagp.2020.10.018_bib0021","series-title":"Applied Longitudinal Data Analysis: Modeling Change and Event Occurrence","author":"Singer","year":"2003"},{"key":"10.1016\/j.jagp.2020.10.018_bib0022","doi-asserted-by":"crossref","DOI":"10.1001\/archpsyc.1983.01790060110016","article-title":"The mini-mental state examination","volume":"40","author":"Folstein","year":"1983","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.jagp.2020.10.018_bib0023","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0109484","article-title":"Factors associated with response to acetylcholinesterase inhibition in dementia: a cohort study from a secondary mental health care case register in London","volume":"9","author":"Perera","year":"2014","journal-title":"PloS One"},{"key":"10.1016\/j.jagp.2020.10.018_bib0024","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2015-008721","article-title":"Cohort profile of the South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLaM BRC) Case Register: current status and recent enhancement of an electronic mental health record-derived data resource","volume":"6","author":"Perera","year":"2016","journal-title":"BMJ Open"},{"key":"10.1016\/j.jagp.2020.10.018_bib0025","doi-asserted-by":"crossref","first-page":"e74262","DOI":"10.1371\/journal.pone.0074262","article-title":"Evaluation of smoking status identification using electronic health records and open-text information in a large mental health case register","volume":"8","author":"Wu","year":"2013","journal-title":"PloS One"},{"key":"10.1016\/j.jagp.2020.10.018_bib0026","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1348\/000712608X377117","article-title":"Standardized or simple effect size: what should be reported?","volume":"100","author":"Baguley","year":"2009","journal-title":"Br J Psychol"},{"key":"10.1016\/j.jagp.2020.10.018_bib0027","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1080\/17405629.2014.963549","article-title":"Interpreting effect sizes when controlling for stability effects in longitudinal autoregressive models: implications for psychological science","volume":"12","author":"Adachi","year":"2015","journal-title":"Eur J Dev Psychol"},{"key":"10.1016\/j.jagp.2020.10.018_bib0028","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1159\/000481136","article-title":"Decline in search speed and verbal memory over 26 years of midlife in a British birth cohort","volume":"49","author":"Davis","year":"2017","journal-title":"Neuroepidemiology"},{"key":"10.1016\/j.jagp.2020.10.018_bib0029","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1016\/S1474-4422(12)70191-6","article-title":"Cognitive reserve in ageing and Alzheimer's disease","volume":"11","author":"Stern","year":"2012","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.jagp.2020.10.018_bib0030","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1192\/bjp.bp.104.008060","article-title":"Risk for coronary heart disease in people with severe mental illness: cross-sectional comparative study in primary care","volume":"188","author":"Osborn","year":"2006","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.jagp.2020.10.018_bib0031","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1192\/bjp.bp.117.202606","article-title":"Mortality gap for people with bipolar disorder and schizophrenia: UK-based cohort study 2000\u20132014","volume":"211","author":"Hayes","year":"2017","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.jagp.2020.10.018_bib0032","doi-asserted-by":"crossref","DOI":"10.1037\/h0032104","article-title":"Development, drop, and death","volume":"6","author":"Riegel","year":"1972","journal-title":"Dev Psychol"},{"key":"10.1016\/j.jagp.2020.10.018_bib0033","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2017\/6210105","article-title":"Decline in memory, visuospatial ability, and crystalized cognitive abilities in older adults: normative aging or terminal decline?","author":"Bendayan","year":"2017","journal-title":"J Aging Res"},{"key":"10.1016\/j.jagp.2020.10.018_bib0034","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1038\/nrd3628","article-title":"Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy","volume":"11","author":"Millan","year":"2012","journal-title":"Nature Reviews Drug Discov"}],"container-title":["The American Journal of Geriatric Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1064748120305431?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1064748120305431?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T22:22:25Z","timestamp":1778797345000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1064748120305431"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":34,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["S1064748120305431"],"URL":"https:\/\/doi.org\/10.1016\/j.jagp.2020.10.018","relation":{},"ISSN":["1064-7481"],"issn-type":[{"value":"1064-7481","type":"print"}],"subject":[],"published":{"date-parts":[[2021,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cognitive Trajectories in Comorbid Dementia With Schizophrenia or Bipolar Disorder: The South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLaM BRC) Case Register","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Geriatric Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jagp.2020.10.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Authors. Published by Elsevier Inc. on behalf of American Association for Geriatric Psychiatry.","name":"copyright","label":"Copyright"}]}}