{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T07:59:49Z","timestamp":1780991989550,"version":"3.54.1"},"reference-count":22,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T00:00:00Z","timestamp":1747094400000},"content-version":"am","delay-in-days":346,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG072975"],"award-info":[{"award-number":["P30 AG072975"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG066509"],"award-info":[{"award-number":["P30 AG066509"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG079280"],"award-info":[{"award-number":["P30 AG079280"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG066519"],"award-info":[{"award-number":["P30 AG066519"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG066506"],"award-info":[{"award-number":["P30 AG066506"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG066508"],"award-info":[{"award-number":["P30 AG066508"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG066444"],"award-info":[{"award-number":["P30 AG066444"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG072973"],"award-info":[{"award-number":["P30 AG072973"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG062421"],"award-info":[{"award-number":["P30 AG062421"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P20 AG068082"],"award-info":[{"award-number":["P20 AG068082"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG066514"],"award-info":[{"award-number":["P30 AG066514"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG062422"],"award-info":[{"award-number":["P30 AG062422"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG062429"],"award-info":[{"award-number":["P30 AG062429"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG066462"],"award-info":[{"award-number":["P30 AG066462"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG066515"],"award-info":[{"award-number":["P30 AG066515"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG066507"],"award-info":[{"award-number":["P30 AG066507"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG066468"],"award-info":[{"award-number":["P30 AG066468"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG072947"],"award-info":[{"award-number":["P30 AG072947"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG066518"],"award-info":[{"award-number":["P30 AG066518"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P20 AG068024"],"award-info":[{"award-number":["P20 AG068024"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG072931"],"award-info":[{"award-number":["P30 AG072931"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P20 AG068053"],"award-info":[{"award-number":["P20 AG068053"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG066512"],"award-info":[{"award-number":["P30 AG066512"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG072958"],"award-info":[{"award-number":["P30 AG072958"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG072972"],"award-info":[{"award-number":["P30 AG072972"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG072977"],"award-info":[{"award-number":["P30 AG072977"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG072946"],"award-info":[{"award-number":["P30 AG072946"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG066511"],"award-info":[{"award-number":["P30 AG066511"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG062715"],"award-info":[{"award-number":["P30 AG062715"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG066546"],"award-info":[{"award-number":["P30 AG066546"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P20 AG068077"],"award-info":[{"award-number":["P20 AG068077"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG072979"],"award-info":[{"award-number":["P30 AG072979"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG072976"],"award-info":[{"award-number":["P30 AG072976"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG062677"],"award-info":[{"award-number":["P30 AG062677"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG072978"],"award-info":[{"award-number":["P30 AG072978"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG072959"],"award-info":[{"award-number":["P30 AG072959"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG066530"],"award-info":[{"award-number":["P30 AG066530"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U24 AG072122"],"award-info":[{"award-number":["U24 AG072122"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["AG054771"],"award-info":[{"award-number":["AG054771"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["AG050515"],"award-info":[{"award-number":["AG050515"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","ajgponline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Geriatric Psychiatry"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1016\/j.jagp.2024.01.015","type":"journal-article","created":{"date-parts":[[2024,1,21]],"date-time":"2024-01-21T07:18:35Z","timestamp":1705821515000},"page":"754-764","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["The Relationship Between First Presenting Neuropsychiatric Symptoms in Older Adults and Autopsy-Confirmed Memory Disorders"],"prefix":"10.1016","volume":"32","author":[{"given":"Jacob S.","family":"Shaw","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeannie M.","family":"Leoutsakos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul B.","family":"Rosenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.jagp.2024.01.015_bib0001","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/S1474-4422(18)30499-X","article-title":"Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016","volume":"18","year":"2019","journal-title":"Lancet Neurol"},{"issue":"5","key":"10.1016\/j.jagp.2024.01.015_bib0002","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/j.jalz.2011.05.2410","article-title":"Neuropsychiatric symptoms in Alzheimer's disease","volume":"7","author":"Lyketsos","year":"2011","journal-title":"Alzheimers Dement"},{"key":"10.1016\/j.jagp.2024.01.015_bib0003","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.dadm.2019.02.006","article-title":"Time course of neuropsychiatric symptoms and cognitive diagnosis in National Alzheimer's Coordinating Centers volunteers","volume":"11","author":"Wise","year":"2019","journal-title":"Alzheimers Dement (Amst)"},{"issue":"7","key":"10.1016\/j.jagp.2024.01.015_bib0004","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.jagp.2013.01.006","article-title":"The association of neuropsychiatric symptoms in MCI with incident dementia and Alzheimer disease","volume":"21","author":"Rosenberg","year":"2013","journal-title":"Am J Geriatr Psychiatry"},{"issue":"7","key":"10.1016\/j.jagp.2024.01.015_bib0005","first-page":"309","article-title":"NPS in normal cognition and the risk of developing MCI and dementia in the presence of late onset NPS (Abstract)","volume":"11","author":"Leoutsakos","year":"2015","journal-title":"Alzheimers Dement"},{"issue":"11","key":"10.1016\/j.jagp.2024.01.015_bib0006","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.3390\/medicina58111586","article-title":"The relationship between neuropsychiatric symptoms and cognitive performance in older adults with normal cognition","volume":"58","author":"Liampas","year":"2022","journal-title":"Medicina (Kaunas)"},{"issue":"21","key":"10.1016\/j.jagp.2024.01.015_bib0007","doi-asserted-by":"crossref","first-page":"e2132","DOI":"10.1212\/WNL.0000000000200256","article-title":"Progression to dementia or reversion to normal cognition in mild cognitive impairment as a function of late-onset neuropsychiatric symptoms","volume":"98","author":"McGirr","year":"2022","journal-title":"Neurology"},{"issue":"4","key":"10.1016\/j.jagp.2024.01.015_bib0008","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.3233\/JAD-160780","article-title":"Risk factors and pathological substrates associated with agitation\/aggression in Alzheimer's disease: a preliminary study using NACC data","volume":"55","author":"Sennik","year":"2017","journal-title":"J Alzheimers Dis"},{"issue":"3","key":"10.1016\/j.jagp.2024.01.015_bib0009","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1097\/WAD.0000000000000250","article-title":"Psychosis in \"cognitively asymptomatic\" elderly subjects is associated with neuritic plaque load, not neurofibrillary tangles","volume":"32","author":"Kim","year":"2018","journal-title":"Alzheimer Dis Assoc Disord"},{"issue":"3","key":"10.1016\/j.jagp.2024.01.015_bib0010","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2022.0729","article-title":"Association of variation in behavioral symptoms with initial cognitive phenotype in adults with dementia confirmed by neuropathology","volume":"5","author":"Pillai","year":"2022","journal-title":"JAMA Netw Open"},{"issue":"4","key":"10.1016\/j.jagp.2024.01.015_bib0011","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1001\/jamapsychiatry.2021.4363","article-title":"Associations between neuropsychiatric symptoms and neuropathological diagnoses of Alzheimer disease and related dementias","volume":"79","author":"Devanand","year":"2022","journal-title":"JAMA Psychiatry"},{"issue":"4","key":"10.1016\/j.jagp.2024.01.015_bib0012","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1002\/alz.12765","article-title":"Neuropathological correlates of neuropsychiatric symptoms in dementia","volume":"19","author":"Gibson","year":"2023","journal-title":"Alzheimers Dement"},{"key":"10.1016\/j.jagp.2024.01.015_bib0013","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1186\/s40478-023-01576-z","article-title":"Neurodegenerative pathologies associated with behavioral and psychological symptoms of dementia in a community-based autopsy cohort","volume":"11","author":"Nelson","year":"2023","journal-title":"Acta Neuropathol Commun"},{"issue":"4","key":"10.1016\/j.jagp.2024.01.015_bib0014","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1097\/01.wad.0000213865.09806.92","article-title":"The Uniform Data Set (UDS): clinical and cognitive variables and descriptive data from Alzheimer Disease Centers","volume":"20","author":"Morris","year":"2006","journal-title":"Alzheimer Dis Assoc Disord"},{"issue":"2","key":"10.1016\/j.jagp.2024.01.015_bib0015","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.jalz.2015.07.492","article-title":"Multisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease","volume":"12","author":"Montine","year":"2016","journal-title":"Alzheimers Dement"},{"issue":"11","key":"10.1016\/j.jagp.2024.01.015_bib0016","doi-asserted-by":"crossref","first-page":"2412","DOI":"10.1212\/WNL.43.11.2412-a","article-title":"The clinical dementia rating (CDR): current version and scoring rules","volume":"43","author":"Morris","year":"1993","journal-title":"Neurology"},{"issue":"6","key":"10.1016\/j.jagp.2024.01.015_bib0017","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1093\/jnen\/nlw026","article-title":"Thal amyloid stages do not significantly impact the correlation between neuropathological change and cognition in the Alzheimer disease continuum","volume":"75","author":"Serrano-Pozo","year":"2016","journal-title":"J Neuropathol Exp Neurol"},{"issue":"1","key":"10.1016\/j.jagp.2024.01.015_bib0018","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1590\/S1980-57642013DN70100004","article-title":"Neuropathology of frontotemporal lobar degeneration: a review","volume":"7","author":"Bahia","year":"2013","journal-title":"Dement Neuropsychol"},{"issue":"2","key":"10.1016\/j.jagp.2024.01.015_bib0019","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.ncl.2017.01.008","article-title":"Frontotemporal dementia","volume":"35","author":"Olney","year":"2017","journal-title":"Neurol Clin."},{"issue":"4","key":"10.1016\/j.jagp.2024.01.015_bib0020","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1177\/0004867419835029","article-title":"Dementia with lewy bodies: challenges in the diagnosis and management","volume":"53","author":"Chin","year":"2019","journal-title":"Aust N Z J Psychiatry"},{"issue":"6","key":"10.1016\/j.jagp.2024.01.015_bib0021","doi-asserted-by":"crossref","first-page":"2423","DOI":"10.1038\/s41380-022-01886-z","article-title":"Alzheimer\u2019s disease neuroimaging initiative. Decoding the heterogeneity of Alzheimer\u2019s disease diagnosis and progression using multilayer networks","volume":"28","author":"Avelar-Pereira","year":"2023","journal-title":"Mol Psychiatry"},{"issue":"1","key":"10.1016\/j.jagp.2024.01.015_bib0022","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1002\/msj.20157","article-title":"Neuropathology of Alzheimer's disease","volume":"77","author":"Perl","year":"2010","journal-title":"Mt Sinai J Med"}],"container-title":["The American Journal of Geriatric Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1064748124000150?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1064748124000150?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,14]],"date-time":"2024-10-14T16:47:44Z","timestamp":1728924464000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1064748124000150"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":22,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["S1064748124000150"],"URL":"https:\/\/doi.org\/10.1016\/j.jagp.2024.01.015","relation":{},"ISSN":["1064-7481"],"issn-type":[{"value":"1064-7481","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Relationship Between First Presenting Neuropsychiatric Symptoms in Older Adults and Autopsy-Confirmed Memory Disorders","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Geriatric Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jagp.2024.01.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 American Association for Geriatric Psychiatry. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}