{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T13:56:13Z","timestamp":1788789373396,"version":"build-2803163510"},"reference-count":82,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaci-inpractice.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Allergy and Clinical Immunology: In Practice"],"published-print":{"date-parts":[[2016,7]]},"DOI":"10.1016\/j.jaip.2016.03.016","type":"journal-article","created":{"date-parts":[[2016,7,6]],"date-time":"2016-07-06T06:02:03Z","timestamp":1467784923000},"page":"613-620","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Other Phenotypes and Treatment of Chronic Rhinosinusitis"],"prefix":"10.1016","volume":"4","author":[{"given":"Robert M.","family":"Naclerio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuad M.","family":"Baroody","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaip.2016.03.016_bib1","first-page":"133","article-title":"Technics and possibilities of nasal endoscopy","volume":"20","author":"Messerklinger","year":"1972","journal-title":"HNO"},{"key":"10.1016\/j.jaip.2016.03.016_bib2","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1148\/radiology.163.3.3575731","article-title":"Paranasal sinuses: CT imaging requirements for endoscopic surgery","volume":"163","author":"Zinreich","year":"1987","journal-title":"Radiology"},{"key":"10.1016\/j.jaip.2016.03.016_bib3","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1046\/j.1365-2273.1997.00862.x","article-title":"A\u00a0study of the CT findings in 100 patients with rhinosinusitis and 100 controls","volume":"22","author":"Jones","year":"1997","journal-title":"Clin Otolaryngol Allied Sci"},{"key":"10.1016\/j.jaip.2016.03.016_bib4","doi-asserted-by":"crossref","first-page":"355","DOI":"10.2500\/105065897781286089","article-title":"Intranasal anatomic variations in pediatric sinusitis","volume":"11","author":"Willner","year":"1997","journal-title":"Am J Rhinol"},{"key":"10.1016\/j.jaip.2016.03.016_bib5","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1002\/alr.21163","article-title":"Sinonasal anatomic variants and asthma are associated with faster development of chronic rhinosinusitis in patients with allergic rhinitis","volume":"3","author":"Sedaghat","year":"2013","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2016.03.016_bib6","first-page":"E17","article-title":"Impaired mucociliary clearance in allergic rhinitis patients is related to a predisposition to rhinosinusitis","volume":"88","author":"Vlastos","year":"2009","journal-title":"Ear Nose Throat J"},{"key":"10.1016\/j.jaip.2016.03.016_bib7","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1136\/adc.2006.096958","article-title":"Primary ciliary dyskinesia: current state of the art","volume":"92","author":"Bush","year":"2007","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.jaip.2016.03.016_bib8","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1586\/14787210.2013.839380","article-title":"Chronic rhinosinusitis and age: is the pathogenesis different?","volume":"11","author":"Mahdavinia","year":"2013","journal-title":"Expert Rev Anti Infect Ther"},{"key":"10.1016\/j.jaip.2016.03.016_bib9","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.jpeds.2003.11.009","article-title":"Chronic rhinosinusitis in young children differs from adults: a histopathology study","volume":"144","author":"Chan","year":"2004","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.jaip.2016.03.016_bib10","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1016\/j.jpeds.2008.11.035","article-title":"Immunopathology of chronic rhinosinusitis in young children","volume":"154","author":"Coffinet","year":"2009","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.jaip.2016.03.016_bib11","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1016\/j.ijporl.2008.07.008","article-title":"Adenoidectomy outcomes in pediatric rhinosinusitis: a meta-analysis","volume":"72","author":"Brietzke","year":"2008","journal-title":"Int J Ped Otorhinolaryngol"},{"key":"10.1016\/j.jaip.2016.03.016_bib12","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1177\/000348940311200709","article-title":"Prevalence of nasal polyps in adults: the Skovde population based study","volume":"112","author":"Johansson","year":"2003","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"10.1016\/j.jaip.2016.03.016_bib13","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1097\/MLG.0b013e318058197a","article-title":"Influence of age on the surgical outcome after endoscopic sinus surgery for chronic rhinosinusitis with nasal polyposis","volume":"117","author":"Lee","year":"2007","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jaip.2016.03.016_bib14","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1016\/j.jaci.2008.02.010","article-title":"Nasal challenge with allergen leads to maxillary sinus inflammation","volume":"121","author":"Baroody","year":"2008","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2016.03.016_bib15","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1177\/0194599811435972","article-title":"Evidence of maxillary sinus inflammation in seasonal allergic rhinitis","volume":"146","author":"Baroody","year":"2012","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.jaip.2016.03.016_bib16","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1001\/archotol.1997.01900020077011","article-title":"Ragweed allergic rhinitis and the paranasal sinuses. A computed tomographic study","volume":"123","author":"Naclerio","year":"1997","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.jaip.2016.03.016_bib17","doi-asserted-by":"crossref","first-page":"281","DOI":"10.2500\/ajra.2014.28.4050","article-title":"Seasonal allergic rhinitis affects sinonasal microbiota","volume":"28","author":"Choi","year":"2014","journal-title":"Am J Rhinol Allergy"},{"key":"10.1016\/j.jaip.2016.03.016_bib18","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1177\/0194599813510892","article-title":"Inconclusive evidence for allergic rhinitis to predict a prolonged or chronic course of acute rhinosinusitis","volume":"150","author":"Frerichs","year":"2014","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.jaip.2016.03.016_bib19","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1067\/mai.2001.117793","article-title":"Allergic inflammation enhances bacterial sinusitis in mice","volume":"108","author":"Blair","year":"2001","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2016.03.016_bib20","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.jaci.2004.04.051","article-title":"Antigen stimulation of TH2 cells augments acute bacterial sinusitis in mice","volume":"114","author":"Yu","year":"2004","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2016.03.016_bib21","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1097\/00005537-200405000-00019","article-title":"Microbial superantigens induce glucocorticoid receptor beta and steroid resistance in a nasal explant model","volume":"114","author":"Fakhri","year":"2004","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jaip.2016.03.016_bib22","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/S0091-6749(94)70068-0","article-title":"Nasal polyps: effects of seasonal allergen exposure","volume":"93","author":"Keith","year":"1994","journal-title":"J\u00a0Allergy Clin Immunol"},{"issue":"Suppl","key":"10.1016\/j.jaip.2016.03.016_bib23","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.jaci.2010.09.034","article-title":"Allergen immunotherapy: a practice parameter third update","volume":"127","author":"Cox","year":"2011","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2016.03.016_bib24","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1097\/MOO.0000000000000048","article-title":"Treatment outcomes in acute invasive fungal rhinosinusitis","volume":"22","author":"Zuniga","year":"2014","journal-title":"Curr Opin Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.jaip.2016.03.016_bib25","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1016\/j.jaci.2015.07.016","article-title":"Immunoglobulin deficiency in patients with chronic rhinosinusitis: systematic review of the literature and meta-analysis","volume":"136","author":"Schwitzgu\u00e9bel","year":"2015","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2016.03.016_bib26","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1046\/j.1365-2249.2000.01131.x","article-title":"Selective IgA deficiency (SIgAD) and common variable immunodeficiency (CVID)","volume":"120","author":"Hammarstrom","year":"2000","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.jaip.2016.03.016_bib27","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1097\/00005537-200102000-00008","article-title":"Immune dysfunction in refractory sinusitis in a tertiary care setting","volume":"111","author":"Chee","year":"2001","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jaip.2016.03.016_bib28","doi-asserted-by":"crossref","first-page":"34","DOI":"10.2500\/ajra.2013.27.3831","article-title":"Antibody deficiency in chronic rhinosinusitis: epidemiology and burden of illness","volume":"27","author":"Ocampo","year":"2013","journal-title":"Am J Rhinol Allergy"},{"key":"10.1016\/j.jaip.2016.03.016_bib29","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0091-6749(97)70223-9","article-title":"Chronic sinusitis: risk factors for extensive disease","volume":"100","author":"Hoover","year":"1997","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2016.03.016_bib30","doi-asserted-by":"crossref","first-page":"241","DOI":"10.2500\/ajra.2011.25.3653","article-title":"Characterization of specific antibody deficiency in adults with medically refractory chronic rhinosinusitis","volume":"25","author":"Carr","year":"2011","journal-title":"Am J Rhinol Allergy"},{"key":"10.1016\/j.jaip.2016.03.016_bib31","doi-asserted-by":"crossref","first-page":"409","DOI":"10.2500\/ajra.2010.24.3532","article-title":"High prevalence of humoral immunodeficiency patients with refractory chronic rhinosinusitis","volume":"24","author":"Alqudah","year":"2010","journal-title":"Am J Rhinol Allergy"},{"key":"10.1016\/j.jaip.2016.03.016_bib32","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1016\/j.jaci.2013.06.049","article-title":"Host-microbial interactions in patients with chronic rhinosinusitis","volume":"133","author":"Hamilos","year":"2014","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2016.03.016_bib33","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1002\/lary.23283","article-title":"The role of extraesophageal reflux in medically and surgically refractory rhinosinusitis","volume":"122","author":"Loehrl","year":"2012","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jaip.2016.03.016_bib34","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1007\/s11882-013-0340-5","article-title":"Gastroesophageal reflux and rhinosinusitis","volume":"13","author":"Katle","year":"2013","journal-title":"Curr Allergy Asthma Rep"},{"key":"10.1016\/j.jaip.2016.03.016_bib35","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1001\/archotol.126.7.831","article-title":"Gastroesophageal reflux contributing to chronic sinus disease in children: a prospective analysis","volume":"126","author":"Phipps","year":"2000","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.jaip.2016.03.016_bib36","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S0194-5998(99)70181-6","article-title":"Outcome of reflux therapy on pediatric chronic sinusitis","volume":"121","author":"Bothwell","year":"1999","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.jaip.2016.03.016_bib37","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.7326\/0003-4819-129-12-199812150-00029","article-title":"Sinusitis and gastroesophageal reflux disease","volume":"129","author":"DiBaise","year":"1998","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jaip.2016.03.016_bib38","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1002\/alr.21333","article-title":"The impact of comorbid gastroesophageal reflux disease on endoscopic sinus surgery quality-of-life outcomes","volume":"4","author":"DeConde","year":"2014","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2016.03.016_bib39","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1097\/MLG.0b013e318159889d","article-title":"Nasal polyposis in Churg-Strauss syndrome","volume":"118","author":"Bacciu","year":"2008","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jaip.2016.03.016_bib40","doi-asserted-by":"crossref","first-page":"e27","DOI":"10.2500\/aap.2014.35.3734","article-title":"Selective IgE deficiency, immune dysregulation, and autoimmunity","volume":"35","author":"Magen","year":"2014","journal-title":"Allergy Asthma Proc"},{"key":"10.1016\/j.jaip.2016.03.016_bib41","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1016\/j.jaci.2011.08.037","article-title":"Evidence for intranasal antinuclear autoantibodies in patients with chronic rhinosinusitis with nasal polyps","volume":"128","author":"Tan","year":"2011","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2016.03.016_bib42","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1007\/s11882-013-0415-3","article-title":"MicroRNA in chronic rhinosinusitis and allergic rhinitis","volume":"14","author":"Zhang","year":"2014","journal-title":"Curr Allergy Asthma Rep"},{"key":"10.1016\/j.jaip.2016.03.016_bib43","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1002\/alr.21054","article-title":"Impact of tobacco smoke on chronic rhinosinusitis: a review of the literature","volume":"2","author":"Reh","year":"2012","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2016.03.016_bib44","doi-asserted-by":"crossref","first-page":"419","DOI":"10.3109\/08958378.2014.910284","article-title":"The effect of smoking on CT score, bacterial colonization and distribution of inflammatory cells in the upper airways of patients with chronic rhinosinusitis","volume":"26","author":"Uhliarova","year":"2014","journal-title":"Inhal Toxicol"},{"key":"10.1016\/j.jaip.2016.03.016_bib45","doi-asserted-by":"crossref","first-page":"562","DOI":"10.2500\/ajra.2009.23.3377","article-title":"Secondhand tobacco smoke exposure and chronic rhinosinusitis: a population-based case-control study","volume":"23","author":"Reh","year":"2009","journal-title":"Am J Rhinol Allergy"},{"key":"10.1016\/j.jaip.2016.03.016_bib46","doi-asserted-by":"crossref","first-page":"297","DOI":"10.2500\/ajra.2014.28.4058","article-title":"Passive smoke exposure in chronic rhinosinusitis as assessed by hair nicotine","volume":"28","author":"Wentzel","year":"2014","journal-title":"Am J Rhinol Allergy"},{"key":"10.1016\/j.jaip.2016.03.016_bib47","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1002\/alr.21232","article-title":"The role of secondhand smoke in sinusitis: a systematic review","volume":"4","author":"Hur","year":"2014","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2016.03.016_bib48","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s11882-015-0540-2","article-title":"The tiology and pathogenesis of chronic rhinosinusitis: a review of current hypotheses","volume":"15","author":"Lam","year":"2015","journal-title":"Curr Allergy Asthma Rep"},{"key":"10.1016\/j.jaip.2016.03.016_bib49","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1002\/lary.21805","article-title":"Staphylococcus aureus biofilms: nemesis of endoscopic sinus surgery","volume":"121","author":"Singhal","year":"2011","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jaip.2016.03.016_bib50","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1016\/j.otohns.2006.03.001","article-title":"Biofilm formation by Staphylococcus aureus and Pseudomonas aeruginosa is associated with an unfavorable evolution after surgery for chronic sinusitis and nasal polyposis","volume":"134","author":"Bendouah","year":"2006","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.jaip.2016.03.016_bib51","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s11882-012-0246-7","article-title":"Role of bacterial and fungal biofilms in chronic rhinosinusitis","volume":"12","author":"Foreman","year":"2012","journal-title":"Curr Allergy Asthma Rep"},{"key":"10.1016\/j.jaip.2016.03.016_bib52","doi-asserted-by":"crossref","first-page":"151ra124","DOI":"10.1126\/scitranslmed.3003783","article-title":"Sinus microbiome diversity depletion and Corynebacterium tuberculostearicum enrichment mediates rhinosinusitis","volume":"4","author":"Abreu","year":"2012","journal-title":"Sci Transl Med"},{"issue":"Suppl 3","key":"10.1016\/j.jaip.2016.03.016_bib53","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.otohns.2006.10.032","article-title":"Clinical practice guideline: adult sinusitis","volume":"137","author":"Rosenfeld","year":"2007","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"suppl 23","key":"10.1016\/j.jaip.2016.03.016_bib54","first-page":"1","article-title":"European position paper on rhinosinusitis and nasal polyps 2012","volume":"50","author":"Fokkens","year":"2012","journal-title":"Rhinology"},{"key":"10.1016\/j.jaip.2016.03.016_bib55","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1111\/j.1398-9995.2010.02439.x","article-title":"Development and implementation of guidelines in allergic rhinitis\u2014an ARIA-GA2LEN paper","volume":"65","author":"Bousquet","year":"2010","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2016.03.016_bib56","doi-asserted-by":"crossref","first-page":"427","DOI":"10.4065\/mcp.2010.0392","article-title":"Rhinosinusitis diagnosis and management for the clinician: a synopsis of recent consensus guidelines","volume":"86","author":"Meltzer","year":"2011","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.jaip.2016.03.016_bib57","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/2045-7022-1-2","article-title":"Diagnostic tools in Rhinology EAACI position paper","volume":"1","author":"Scadding","year":"2011","journal-title":"Clin Transl Allergy"},{"key":"10.1016\/j.jaip.2016.03.016_bib58","first-page":"287","article-title":"Chronic rhinosinusitis: contrasts between children and adult patients","volume":"20","author":"Lusk","year":"2007","journal-title":"Clin Allergy Immunol"},{"key":"10.1016\/j.jaip.2016.03.016_bib59","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1111\/j.1398-9995.2009.01938.x","article-title":"Long-term study of fluticasone propionate aqueous nasal spray in acute and maintenance therapy of nasal polyposis","volume":"64","author":"Jankowski","year":"2009","journal-title":"Allergy"},{"issue":"8","key":"10.1016\/j.jaip.2016.03.016_bib60","first-page":"CD009274","article-title":"Topical steroid for chronic rhinosinusitis without polyps","author":"Snidvongs","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jaip.2016.03.016_bib61","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1016\/j.otohns.2009.08.006","article-title":"Topical steroids in chronic rhinosinusitis without polyps: a systematic review and meta-analysis","volume":"141","author":"Kalish","year":"2009","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.jaip.2016.03.016_bib62","doi-asserted-by":"crossref","first-page":"419","DOI":"10.4193\/Rhin09.024","article-title":"Effective treatment of mild-to-moderate nasal polyposis with fluticasone delivered by a novel device","volume":"47","author":"Vlckova","year":"2009","journal-title":"Rhinology"},{"issue":"7","key":"10.1016\/j.jaip.2016.03.016_bib63","first-page":"CD005232","article-title":"Oral steroids for nasal polyps","author":"Martinez-Devesa","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jaip.2016.03.016_bib64","doi-asserted-by":"crossref","first-page":"2459","DOI":"10.1002\/lary.20653","article-title":"Long-term outcomes from the English national comparative audit of surgery for nasal polyposis and chronic rhinosinusitis","volume":"119","author":"Hopkins","year":"2009","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jaip.2016.03.016_bib65","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1080\/00016480802298089","article-title":"A\u00a0randomized prospective study comparing medical and medical-surgical treatment of nasal polyposis by CT","volume":"129","author":"Blomqvist","year":"2009","journal-title":"Acta Otolaryngol"},{"key":"10.1016\/j.jaip.2016.03.016_bib66","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1097\/00005537-200405000-00027","article-title":"Evaluation of medical and surgical management of chronic rhinosinusitis: a prospective randomized controlled trial","volume":"114","author":"Ragab","year":"2004","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jaip.2016.03.016_bib67","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1002\/alr.20063","article-title":"Medical therapy vs surgery for chronic rhinosinusitis: a prospective, multi-institutional study with 1-year follow-up","volume":"1","author":"Smith","year":"2011","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2016.03.016_bib68","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1007\/s00405-010-1233-z","article-title":"Extensive endoscopic sinus surgery: does this reduce the revision rate for nasal polyposis?","volume":"267","author":"Masterson","year":"2010","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"10.1016\/j.jaip.2016.03.016_bib69","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1177\/000348941112000304","article-title":"Revision rates after endoscopic sinus surgery: a recurrence analysis","volume":"120","author":"Mendelsohn","year":"2011","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"10.1016\/j.jaip.2016.03.016_bib70","doi-asserted-by":"crossref","first-page":"381","DOI":"10.2500\/ajr.2008.22.3189","article-title":"Topical antimicrobials in the management of chronic rhinosinusitis: a systematic review","volume":"22","author":"Lim","year":"2008","journal-title":"Am J Rhinol"},{"issue":"5","key":"10.1016\/j.jaip.2016.03.016_bib71","first-page":"CD008233","article-title":"Systemic antibiotics for chronic rhinosinusitis without nasal polyps in adults","author":"Piromchai","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jaip.2016.03.016_bib72","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1111\/j.1398-9995.2011.02693.x","article-title":"Lack of efficacy of long-term, low-dose azithromycin in chronic rhinosinusitis: a randomized controlled trial","volume":"66","author":"Videler","year":"2011","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2016.03.016_bib73","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1016\/j.jaci.2010.02.020","article-title":"Oral steroids and doxycycline: two different approaches to treat nasal polyps","volume":"125","author":"Van Zele","year":"2010","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2016.03.016_bib74","doi-asserted-by":"crossref","first-page":"34","DOI":"10.2500\/ajr.2008.22.3122","article-title":"Baby shampoo nasal irrigations for the symptomatic post-functional endoscopic sinus surgery patient","volume":"22","author":"Chiu","year":"2008","journal-title":"Am J Rhinol"},{"key":"10.1016\/j.jaip.2016.03.016_bib75","first-page":"71","article-title":"Sulphurous thermal water inhalations in the treatment of chronic rhinosinusitis","volume":"48","author":"Salami","year":"2010","journal-title":"Rhinology"},{"key":"10.1016\/j.jaip.2016.03.016_bib76","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.3109\/02770900903242704","article-title":"Methotrexate: can it be a choice for nasal polyposis in aspirin exacerbated respiratory disease?","volume":"46","author":"Buyukozturk","year":"2009","journal-title":"J\u00a0Asthma"},{"issue":"8","key":"10.1016\/j.jaip.2016.03.016_bib77","first-page":"CD008263","article-title":"Topical and systemic antifungal therapy for the symptomatic treatment of chronic rhinosinusitis","author":"Sacks","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jaip.2016.03.016_bib78","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1097\/MLG.0b013e318165e324","article-title":"Nasal pepsin assay and pH monitoring in chronic rhinosinusitis","volume":"118","author":"Ozmen","year":"2008","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jaip.2016.03.016_bib79","first-page":"196","article-title":"Natural treatment of chronic rhinosinusitis","volume":"11","author":"Helms","year":"2006","journal-title":"Altern Med Rev"},{"key":"10.1016\/j.jaip.2016.03.016_bib80","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/s11882-008-0041-7","article-title":"The clinical effectiveness of aspirin desensitization in chronic rhinosinusitis","volume":"8","author":"Williams","year":"2008","journal-title":"Curr Allergy Asthma Rep"},{"key":"10.1016\/j.jaip.2016.03.016_bib81","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1017\/S0022215107000515","article-title":"Intranasal lysine-aspirin administration decreases polyp volume in patients with aspirin-intolerant asthma","volume":"121","author":"Ogata","year":"2007","journal-title":"J\u00a0Laryngol Otol"},{"key":"10.1016\/j.jaip.2016.03.016_bib82","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1038\/nm.2754","article-title":"Therapies for allergic inflammation: refining strategies to induce tolerance","volume":"18","author":"Akdis","year":"2012","journal-title":"Nat Med"}],"container-title":["The Journal of Allergy and Clinical Immunology: In Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S221321981630054X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S221321981630054X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T05:10:42Z","timestamp":1761973842000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S221321981630054X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7]]},"references-count":82,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["S221321981630054X"],"URL":"https:\/\/doi.org\/10.1016\/j.jaip.2016.03.016","relation":{},"ISSN":["2213-2198"],"issn-type":[{"value":"2213-2198","type":"print"}],"subject":[],"published":{"date-parts":[[2016,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Other Phenotypes and Treatment of Chronic Rhinosinusitis","name":"articletitle","label":"Article Title"},{"value":"The Journal of Allergy and Clinical Immunology: In Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaip.2016.03.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 American Academy of Allergy, Asthma & Immunology","name":"copyright","label":"Copyright"}]}}