{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T02:16:06Z","timestamp":1783390566094,"version":"3.54.6"},"reference-count":72,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,8,20]],"date-time":"2018-08-20T00:00:00Z","timestamp":1534723200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100003943","name":"Mastocytosis Society","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100003943","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004334","name":"Merck","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004334","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004328","name":"Genentech","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004328","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004336","name":"Novartis","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004336","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100003943","name":"Mastocytosis Society","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100003943","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004339","name":"Sanofi","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004339","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaci-inpractice.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Allergy and Clinical Immunology: In Practice"],"published-print":{"date-parts":[[2019,4]]},"DOI":"10.1016\/j.jaip.2018.07.032","type":"journal-article","created":{"date-parts":[[2018,8,8]],"date-time":"2018-08-08T12:20:33Z","timestamp":1533730833000},"page":"1157-1165.e6","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"title":["The Mastocytosis Society Survey on Mast Cell Disorders: Part 2\u2014Patient Clinical Experiences and Beyond"],"prefix":"10.1016","volume":"7","author":[{"given":"Nancy","family":"Russell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Jennings","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Blair","family":"Jennings","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerie","family":"Slee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Sterling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana","family":"Castells","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Valent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cem","family":"Akin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaip.2018.07.032_bib1","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1111\/j.1365-2222.2007.02804.x","article-title":"Prevalence of allergy and anaphylactic symptoms in 210 adult and pediatric patients with mastocytosis in Spain: a study of the Spanish network on mastocytosis (REMA)","volume":"37","author":"Gonzalez de Olano","year":"2007","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaip.2018.07.032_bib2","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1111\/j.1398-9995.2007.01569.x","article-title":"Anaphylaxis in patients with mastocytosis: a study on history, clinical features and risk factors in 120 patients","volume":"63","author":"Brockow","year":"2008","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2018.07.032_bib3","doi-asserted-by":"crossref","first-page":"5727","DOI":"10.1182\/blood-2009-02-205237","article-title":"Systemic mastocytosis in 342 consecutive adults: survival studies and prognostic factors","volume":"113","author":"Lim","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.jaip.2018.07.032_bib4","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1111\/all.12126","article-title":"Mast cell activation syndromes: definition and classification","volume":"68","author":"Valent","year":"2013","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2018.07.032_bib5","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/cea.12225","article-title":"High prevalence of anaphylaxis in patients with systemic mastocytosis\u2014a single-centre experience","volume":"44","author":"Gulen","year":"2014","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaip.2018.07.032_bib6","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1111\/j.1365-2362.2007.01807.x","article-title":"Standards and standardization in mastocytosis: consensus statements on diagnostics, treatment recommendations and response criteria","volume":"37","author":"Valent","year":"2007","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.jaip.2018.07.032_bib7","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1159\/000328760","article-title":"Definitions, criteria and global classification of mast cell disorders with special reference to mast cell activation syndromes: a consensus proposal","volume":"157","author":"Valent","year":"2012","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.jaip.2018.07.032_bib8","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1159\/000096442","article-title":"Diagnostic and subdiagnostic accumulation of mast cells in the bone marrow of patients with anaphylaxis: monoclonal mast cell activation syndrome","volume":"142","author":"Sonneck","year":"2007","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.jaip.2018.07.032_bib9","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1016\/j.jaci.2010.08.035","article-title":"Mast cell activation syndrome: proposed diagnostic criteria","volume":"126","author":"Akin","year":"2010","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2018.07.032_bib10","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1016\/j.jaci.2010.02.019","article-title":"Clinical, biological, and molecular characteristics of clonal mast cell disorders presenting with systemic mast cell activation symptoms","volume":"125","author":"Alvarez-Twose","year":"2010","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2018.07.032_bib11","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1159\/000323763","article-title":"Clinical and laboratory parameters of mast cell activation as basis for the formulation of diagnostic criteria","volume":"156","author":"Valent","year":"2011","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.jaip.2018.07.032_bib12","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1056\/NEJM198706253162603","article-title":"Tryptase levels as an indicator of mast-cell activation in systemic anaphylaxis and mastocytosis","volume":"316","author":"Schwartz","year":"1987","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jaip.2018.07.032_bib13","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.jaci.2014.11.035","article-title":"Clonal mast cell disorders in patients with severe Hymenoptera venom allergy and normal serum tryptase levels","volume":"136","author":"Zanotti","year":"2015","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2018.07.032_bib14","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s11882-015-0582-5","article-title":"Hymenoptera allergy and mast cell activation syndromes","volume":"16","author":"Bonadonna","year":"2016","journal-title":"Curr Allergy Asthma Rep"},{"key":"10.1016\/j.jaip.2018.07.032_bib15","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.jaip.2013.09.004","article-title":"The Mastocytosis Society survey on mast cell disorders: patient experiences and perceptions","volume":"2","author":"Jennings","year":"2014","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2018.07.032_bib16","doi-asserted-by":"crossref","first-page":"2366","DOI":"10.1182\/blood-2006-04-015545","article-title":"KIT mutation in mast cells and other bone marrow hematopoietic cell lineages in systemic mast cell disorders: a prospective study of the Spanish Network on Mastocytosis (REMA) in a series of 113 patients","volume":"108","author":"Garcia-Montero","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.jaip.2018.07.032_bib17","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s00277-013-1964-1","article-title":"The KIT D816V expressed allele burden for diagnosis and disease monitoring of systemic mastocytosis","volume":"93","author":"Erben","year":"2014","journal-title":"Ann Hematol"},{"key":"10.1016\/j.jaip.2018.07.032_bib18","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1002\/ajh.23672","article-title":"Sensitive KIT D816V mutation analysis of blood as a diagnostic test in mastocytosis","volume":"89","author":"Kristensen","year":"2014","journal-title":"Am J Hematol"},{"key":"10.1016\/j.jaip.2018.07.032_bib19","doi-asserted-by":"crossref","first-page":"2520","DOI":"10.1002\/jbmr.2269","article-title":"The recent prevalence of osteoporosis and low bone mass in the United States based on bone mineral density at the femoral neck or lumbar spine","volume":"29","author":"Wright","year":"2014","journal-title":"J\u00a0Bone Miner Res"},{"key":"10.1016\/j.jaip.2018.07.032_bib20","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.bone.2007.07.008","article-title":"Osteoporosis in children and adolescents","volume":"41","author":"Bianchi","year":"2007","journal-title":"Bone"},{"key":"10.1016\/j.jaip.2018.07.032_bib21","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.jocd.2014.01.007","article-title":"2013 Pediatric Position Development Conference: executive summary and reflections","volume":"17","author":"Gordon","year":"2014","journal-title":"J\u00a0Clin Densitom"},{"key":"10.1016\/j.jaip.2018.07.032_bib22","doi-asserted-by":"crossref","first-page":"2359","DOI":"10.1007\/s00198-014-2794-2","article-title":"Clinician\u2019s guide to prevention and treatment of osteoporosis","volume":"25","author":"Cosman","year":"2014","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.jaip.2018.07.032_bib23","series-title":"Bone health and osteoporosis: a report of the Surgeon General","year":"2004"},{"key":"10.1016\/j.jaip.2018.07.032_bib24","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1007\/s11657-014-0182-3","article-title":"Estimating prevalence of osteoporosis: examples from industrialized countries","volume":"9","author":"Wade","year":"2014","journal-title":"Arch Osteoporos"},{"key":"10.1016\/j.jaip.2018.07.032_bib25","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.jocd.2013.08.004","article-title":"Executive summary of the 2013 International Society for Clinical Densitometry Position Development Conference on bone densitometry","volume":"16","author":"Schousboe","year":"2013","journal-title":"J\u00a0Clin Densitom"},{"key":"10.1016\/j.jaip.2018.07.032_bib26","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1111\/all.12436","article-title":"Proposed diagnostic algorithm for patients with suspected mastocytosis: a proposal of the European Competence Network on Mastocytosis","volume":"69","author":"Valent","year":"2014","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2018.07.032_bib27","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/S0145-2126(01)00038-8","article-title":"Diagnostic criteria and classification of mastocytosis: a consensus proposal","volume":"25","author":"Valent","year":"2001","journal-title":"Leuk Res"},{"key":"10.1016\/j.jaip.2018.07.032_bib28","series-title":"World Health Organization (WHO) classification of tumours. Pathology and genetics. Tumours of haematopoietic and lymphoid tissues","first-page":"54","article-title":"Mastocytosis (mast cell disease)","author":"Horny","year":"2008"},{"key":"10.1016\/j.jaip.2018.07.032_bib29","series-title":"World Health Organization (WHO) classification of tumours. Pathology and genetics. Tumours of haematopoietic and lymphoid tissues","first-page":"291","article-title":"Mastocytosis","author":"Valent","year":"2001"},{"key":"10.1016\/j.jaip.2018.07.032_bib30","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1111\/j.1365-2362.2009.02184.x","article-title":"Elevated tryptase levels selectively cluster in myeloid neoplasms: a novel diagnostic approach and screen marker in clinical haematology","volume":"39","author":"Sperr","year":"2009","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.jaip.2018.07.032_bib31","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1016\/j.jaci.2013.11.039","article-title":"Mendelian inheritance of elevated serum tryptase associated with atopy and connective tissue abnormalities","volume":"133","author":"Lyons","year":"2014","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2018.07.032_bib32","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1038\/ng.3696","article-title":"Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number","volume":"48","author":"Lyons","year":"2016","journal-title":"Nat Genet"},{"key":"10.1016\/j.jaip.2018.07.032_bib33","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1111\/bjd.14004","article-title":"Clinical features and course of cutaneous mastocytosis in 133 children","volume":"174","author":"Schena","year":"2016","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaip.2018.07.032_bib34","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.iac.2014.02.003","article-title":"Diagnostic criteria and classification of mastocytosis in 2014","volume":"34","author":"Akin","year":"2014","journal-title":"Immunol Allergy Clin North Am"},{"key":"10.1016\/j.jaip.2018.07.032_bib35","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1111\/j.1751-553X.2012.01427.x","article-title":"Current state of biology and diagnosis of clonal mast cell diseases in adults","volume":"34","author":"Alvarez-Twose","year":"2012","journal-title":"Int J Lab Hematol"},{"key":"10.1016\/j.jaip.2018.07.032_bib36","doi-asserted-by":"crossref","first-page":"2393","DOI":"10.1182\/blood-2012-09-458521","article-title":"International Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT) & European Competence Network on Mastocytosis (ECNM) consensus response criteria in advanced systemic mastocytosis","volume":"121","author":"Gotlib","year":"2013","journal-title":"Blood"},{"key":"10.1016\/j.jaip.2018.07.032_bib37","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1159\/000101711","article-title":"Mastocytosis: state of the art","volume":"74","author":"Horny","year":"2007","journal-title":"Pathobiology"},{"key":"10.1016\/j.jaip.2018.07.032_bib38","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/j.jaci.2008.11.018","article-title":"Clonal mast cell disorders in patients with systemic reactions to Hymenoptera stings and increased serum tryptase levels","volume":"123","author":"Bonadonna","year":"2009","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2018.07.032_bib39","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1038\/leu.2015.24","article-title":"KIT mutation analysis in mast cell neoplasms: recommendations of the European Competence Network on Mastocytosis","volume":"29","author":"Arock","year":"2015","journal-title":"Leukemia"},{"key":"10.1016\/j.jaip.2018.07.032_bib40","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1056\/NEJMra1409760","article-title":"Mast cells, mastocytosis, and related disorders","volume":"373","author":"Theoharides","year":"2015","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jaip.2018.07.032_bib41","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1038\/modpathol.2013.117","article-title":"Adult-onset mastocytosis in the skin is highly suggestive of systemic mastocytosis","volume":"27","author":"Berezowska","year":"2014","journal-title":"Mod Pathol"},{"key":"10.1016\/j.jaip.2018.07.032_bib42","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1309\/AJCPPXHMN5CJOXHZ","article-title":"Mastocytosis: an unusual clonal disorder of bone marrow-derived hematopoietic progenitor cells","volume":"132","author":"Horny","year":"2009","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.jaip.2018.07.032_bib43","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.jmoldx.2010.10.004","article-title":"Improved detection of the KIT D816V mutation in patients with systemic mastocytosis using a quantitative and highly sensitive real-time qPCR assay","volume":"13","author":"Kristensen","year":"2011","journal-title":"J\u00a0Mol Diagn"},{"key":"10.1016\/j.jaip.2018.07.032_bib44","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1038\/modpathol.2015.72","article-title":"Detection of the KIT D816V mutation in peripheral blood of systemic mastocytosis: diagnostic implications","volume":"28","author":"Jara-Acevedo","year":"2015","journal-title":"Mod Pathol"},{"key":"10.1016\/j.jaip.2018.07.032_bib45","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1111\/all.12409","article-title":"The KIT D816V allele burden predicts survival in patients with mastocytosis and correlates with the WHO type of the disease","volume":"69","author":"Hoermann","year":"2014","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2018.07.032_bib46","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/j.jaci.2009.05.003","article-title":"Prognosis in adult indolent systemic mastocytosis: a long-term study of the Spanish Network on Mastocytosis in a series of 145 patients","volume":"124","author":"Escribano","year":"2009","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2018.07.032_bib47","doi-asserted-by":"crossref","first-page":"75.e1","DOI":"10.1016\/j.amjmed.2012.07.018","article-title":"Bone complications of mastocytosis: a link between clinical and biological characteristics","volume":"126","author":"Guillaume","year":"2013","journal-title":"Am J Med"},{"key":"10.1016\/j.jaip.2018.07.032_bib48","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1111\/j.1398-9995.2011.02780.x","article-title":"High prevalence of fractures and osteoporosis in patients with indolent systemic mastocytosis","volume":"67","author":"van der Veer","year":"2012","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2018.07.032_bib49","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.iac.2014.01.011","article-title":"Bone involvement and osteoporosis in mastocytosis","volume":"34","author":"Rossini","year":"2014","journal-title":"Immunol Allergy Clin North Am"},{"key":"10.1016\/j.jaip.2018.07.032_bib50","doi-asserted-by":"crossref","first-page":"356","DOI":"10.7326\/0003-4819-154-5-201103010-00307","article-title":"Screening for osteoporosis: U.S. Preventive Services Task Force recommendation statement","volume":"154","year":"2011","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jaip.2018.07.032_bib51","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/j.bone.2011.07.004","article-title":"Bone mineral density, bone turnover markers and fractures in patients with indolent systemic mastocytosis","volume":"49","author":"Rossini","year":"2011","journal-title":"Bone"},{"key":"10.1016\/j.jaip.2018.07.032_bib52","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.semarthrit.2006.03.004","article-title":"The role of mast cells in osteoporosis","volume":"36","author":"Chiappetta","year":"2006","journal-title":"Semin Arthritis Rheum"},{"key":"10.1016\/j.jaip.2018.07.032_bib53","doi-asserted-by":"crossref","first-page":"2325","DOI":"10.1007\/s00198-013-2305-x","article-title":"Increased osteoblast and osteoclast indices in individuals with systemic mastocytosis","volume":"24","author":"Seitz","year":"2013","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.jaip.2018.07.032_bib54","doi-asserted-by":"crossref","first-page":"2142","DOI":"10.1152\/japplphysiol.00564.2003","article-title":"Invited review: pathogenesis of osteoporosis","volume":"95","author":"Seeman","year":"2003","journal-title":"J\u00a0Appl Physiol"},{"key":"10.1016\/j.jaip.2018.07.032_bib55","series-title":"Health, United States, 2010: with special feature on death and dying","author":"National Center for Health Statistics","year":"2011"},{"key":"10.1016\/j.jaip.2018.07.032_bib56","first-page":"1","article-title":"Summary health statistics for U.S. adults: national health interview survey, 2012","volume":"10","author":"Blackwell","year":"2014","journal-title":"Vital Health Stat"},{"key":"10.1016\/j.jaip.2018.07.032_bib57","first-page":"e28","article-title":"Heart disease and stroke statistics--2014 update: a report from the American Heart Association","volume":"129","author":"Go","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.jaip.2018.07.032_bib58","first-page":"e46","article-title":"Heart disease and stroke statistics--2010 update: a report from the American Heart Association","volume":"121","author":"Lloyd-Jones","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.jaip.2018.07.032_bib59","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s11882-004-0043-z","article-title":"The role of mast cells in common gastrointestinal diseases","volume":"4","author":"Siddiqui","year":"2004","journal-title":"Curr Allergy Asthma Rep"},{"key":"10.1016\/j.jaip.2018.07.032_bib60","doi-asserted-by":"crossref","first-page":"S219","DOI":"10.1007\/s00011-009-0134-3","article-title":"Histamine intolerance: a metabolic disease?","volume":"59","author":"Schwelberger","year":"2010","journal-title":"Inflamm Res"},{"key":"10.1016\/j.jaip.2018.07.032_bib61","first-page":"244","article-title":"Mastocytosis and adverse reactions to biogenic amines and histamine-releasing foods: what is the evidence?","volume":"63","author":"Vlieg-Boerstra","year":"2005","journal-title":"Neth J Med"},{"key":"10.1016\/j.jaip.2018.07.032_bib62","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1097\/DAD.0b013e31826330bf","article-title":"Familial urticaria pigmentosa: report of a family and review of the role of KIT mutations","volume":"35","author":"Fett","year":"2013","journal-title":"Am J Dermatopathol"},{"key":"10.1016\/j.jaip.2018.07.032_bib63","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1038\/jid.2012.394","article-title":"A\u00a0c-kit mutation in exon 18 in familial mastocytosis","volume":"133","author":"Wohrl","year":"2013","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jaip.2018.07.032_bib64","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/j.jaci.2012.11.040","article-title":"Somatic D816V KIT mutation in a case of adult-onset familial mastocytosis","volume":"131","author":"Zanotti","year":"2013","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2018.07.032_bib65","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1016\/j.jaci.2014.06.007","article-title":"Familial hypertryptasemia with associated mast cell activation syndrome","volume":"134","author":"Sabato","year":"2014","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2018.07.032_bib66","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.jaci.2015.05.008","article-title":"Clinical, immunophenotypic, and molecular characteristics of well-differentiated systemic mastocytosis","volume":"137","author":"Alvarez-Twose","year":"2016","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2018.07.032_bib67","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1007\/s00508-004-0253-3","article-title":"The European Competence Network on Mastocytosis (ECNM)","volume":"116","author":"Valent","year":"2004","journal-title":"Wien Klin Wochenschr"},{"key":"10.1016\/j.jaip.2018.07.032_bib68","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1007\/s00508-012-0293-z","article-title":"European Competence Network on Mastocytosis (ECNM): 10-year jubilee, update, and future perspectives","volume":"124","author":"Valent","year":"2012","journal-title":"Wien Klin Wochenschr"},{"key":"10.1016\/j.jaip.2018.07.032_bibE1","series-title":"SEER Cancer Statistics Review, 1975-2012, (Prevalence Tables)","year":"2014"},{"key":"10.1016\/j.jaip.2018.07.032_bibE2","first-page":"1","article-title":"Summary health statistics for U.S. adults: national health interview survey, 2012","volume":"10","author":"Blackwell","year":"2014","journal-title":"Vital Health Stat"},{"key":"10.1016\/j.jaip.2018.07.032_bibE3","first-page":"e46","article-title":"Heart disease and stroke statistics--2010 update: a report from the American Heart Association","volume":"121","author":"Lloyd-Jones","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.jaip.2018.07.032_bibE4","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.jaip.2013.09.004","article-title":"The Mastocytosis Society survey on mast cell disorders: patient experiences and perceptions","volume":"2","author":"Jennings","year":"2014","journal-title":"J\u00a0Allergy Clin Immunol Pract"}],"container-title":["The Journal of Allergy and Clinical Immunology: In Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213219818304690?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213219818304690?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T05:17:32Z","timestamp":1761974252000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213219818304690"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":72,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,4]]}},"alternative-id":["S2213219818304690"],"URL":"https:\/\/doi.org\/10.1016\/j.jaip.2018.07.032","relation":{},"ISSN":["2213-2198"],"issn-type":[{"value":"2213-2198","type":"print"}],"subject":[],"published":{"date-parts":[[2019,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Mastocytosis Society Survey on Mast Cell Disorders: Part 2\u2014Patient Clinical Experiences and Beyond","name":"articletitle","label":"Article Title"},{"value":"The Journal of Allergy and Clinical Immunology: In Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaip.2018.07.032","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 The Authors. Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology.","name":"copyright","label":"Copyright"}]}}