{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T02:00:10Z","timestamp":1788487210303,"version":"build-2803163510"},"reference-count":40,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100008366","name":"Danmarks Lungeforening","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008366","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001734","name":"K\u00f8benhavns Universitet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001734","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004330","name":"GlaxoSmithKline","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004330","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002918","name":"Gentofte Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002918","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003491","name":"Herlev Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003491","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003554","name":"Lundbeckfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003554","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008363","name":"Kr\u00e6ftens Bek\u00e6mpelse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008363","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaci-inpractice.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Allergy and Clinical Immunology: In Practice"],"published-print":{"date-parts":[[2019,7]]},"DOI":"10.1016\/j.jaip.2019.02.021","type":"journal-article","created":{"date-parts":[[2019,3,2]],"date-time":"2019-03-02T11:02:20Z","timestamp":1551524540000},"page":"1783-1792.e8","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":50,"title":["Role and Impact of Chronic Cough in Individuals with Asthma From the General Population"],"prefix":"10.1016","volume":"7","author":[{"given":"Yunus","family":"\u00c7olak","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoaib","family":"Afzal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Lange","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars C.","family":"Laursen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00f8rge G.","family":"Nordestgaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morten","family":"Dahl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaip.2019.02.021_bib1","doi-asserted-by":"crossref","first-page":"1S","DOI":"10.1378\/chest.129.1_suppl.1S","article-title":"Diagnosis and management of cough executive summary: ACCP evidence-based clinical practice guidelines","volume":"129","author":"Irwin","year":"2006","journal-title":"Chest"},{"key":"10.1016\/j.jaip.2019.02.021_bib2","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1183\/09031936.04.00027804","article-title":"The diagnosis and management of chronic cough","volume":"24","author":"Morice","year":"2004","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaip.2019.02.021_bib3","doi-asserted-by":"crossref","first-page":"i1","DOI":"10.1136\/thx.2006.065144","article-title":"Recommendations for the management of cough in adults","volume":"61","author":"Morice","year":"2006","journal-title":"Thorax"},{"key":"10.1016\/j.jaip.2019.02.021_bib4","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1378\/chest.130.6.1839","article-title":"Prevalence of depressive symptoms among patients with chronic cough","volume":"130","author":"Dicpinigaitis","year":"2006","journal-title":"Chest"},{"key":"10.1016\/j.jaip.2019.02.021_bib5","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1378\/chest.07-0141","article-title":"Impact of cough across different chronic respiratory diseases: comparison of two cough-specific health-related quality of life questionnaires","volume":"134","author":"Polley","year":"2008","journal-title":"Chest"},{"key":"10.1016\/j.jaip.2019.02.021_bib6","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1001\/archinte.158.15.1657","article-title":"Impact of chronic cough on quality of life","volume":"158","author":"French","year":"1998","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.jaip.2019.02.021_bib7","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1016\/j.jaci.2007.09.019","article-title":"Asthma control in Europe: a real-world evaluation based on an international population-based study","volume":"120","author":"Cazzoletti","year":"2007","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2019.02.021_bib8","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1097\/ACI.0b013e328334e75f","article-title":"Interrupting the cough reflex in asthma","volume":"10","author":"Smith","year":"2010","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2019.02.021_bib9","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1183\/09031936.01.00098701","article-title":"Determinants of cough in young adults participating in the European Community Respiratory Health Survey","volume":"18","author":"Janson","year":"2001","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaip.2019.02.021_bib10","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.jaci.2009.06.010","article-title":"Phenotypic determinants of uncontrolled asthma","volume":"124","author":"Siroux","year":"2009","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2019.02.021_bib11","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1164\/rccm.201502-0302OC","article-title":"Characteristics and prognosis of never-smokers and smokers with asthma in the Copenhagen General Population Study: a prospective cohort study","volume":"192","author":"\u00c7olak","year":"2015","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaip.2019.02.021_bib12","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.chest.2017.05.038","article-title":"Risk factors for chronic cough among 14,669 individuals from the general population","volume":"152","author":"\u00c7olak","year":"2017","journal-title":"Chest"},{"key":"10.1016\/j.jaip.2019.02.021_bib13","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1136\/thorax.58.4.339","article-title":"Development of a symptom specific health status measure for patients with chronic cough: Leicester Cough Questionnaire (LCQ)","volume":"58","author":"Birring","year":"2003","journal-title":"Thorax"},{"key":"10.1016\/j.jaip.2019.02.021_bib14","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1136\/thx.2006.067413","article-title":"Chronic cough: how do cough reflex sensitivity and subjective assessments correlate with objective cough counts during ambulatory monitoring?","volume":"62","author":"Decalmer","year":"2007","journal-title":"Thorax"},{"key":"10.1016\/j.jaip.2019.02.021_bib15","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1159\/000321231","article-title":"Validated methods of cough assessment: a systematic review of the literature","volume":"81","author":"Leconte","year":"2011","journal-title":"Respiration"},{"key":"10.1016\/j.jaip.2019.02.021_bib16","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1111\/j.1752-699X.2012.00297.x","article-title":"New Danish reference values for spirometry","volume":"7","author":"L\u00f8kke","year":"2013","journal-title":"Clin Respir J"},{"key":"10.1016\/j.jaip.2019.02.021_bib17","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1016\/j.chest.2016.02.676","article-title":"Objective cough frequency, airway inflammation, and disease control in asthma","volume":"149","author":"Marsden","year":"2016","journal-title":"Chest"},{"key":"10.1016\/j.jaip.2019.02.021_bib18","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1136\/thorax.56.2.138","article-title":"Patient weighting of importance of asthma symptoms","volume":"56","author":"Osman","year":"2001","journal-title":"Thorax"},{"key":"10.1016\/j.jaip.2019.02.021_bib19","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1136\/thx.2008.103069","article-title":"Heterogeneity of asthma according to blood inflammatory patterns","volume":"64","author":"Nadif","year":"2009","journal-title":"Thorax"},{"key":"10.1016\/j.jaip.2019.02.021_bib21","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s00408-013-9543-8","article-title":"Cough in asthma is due to eosinophilic airway inflammation: a pro\/con debate","volume":"192","author":"Niimi","year":"2014","journal-title":"Lung"},{"key":"10.1016\/j.jaip.2019.02.021_bib22","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1373\/clinchem.2016.267450","article-title":"Association of blood eosinophil and blood neutrophil counts with asthma exacerbations in the Copenhagen General Population Study","volume":"63","author":"Vedel-Krogh","year":"2017","journal-title":"Clin Chem"},{"key":"10.1016\/j.jaip.2019.02.021_bib23","doi-asserted-by":"crossref","first-page":"S143","DOI":"10.1513\/AnnalsATS.201306-168AW","article-title":"Eosinophilic phenotypes of airway disease","volume":"10","author":"Pavord","year":"2013","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.jaip.2019.02.021_bib24","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1378\/chest.130.2.362","article-title":"Interpreting the histopathology of chronic cough: a prospective, controlled, comparative study","volume":"130","author":"Irwin","year":"2006","journal-title":"Chest"},{"key":"10.1016\/j.jaip.2019.02.021_bib25","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.jaci.2005.07.010","article-title":"Nature of airway inflammation and remodeling in chronic cough","volume":"116","author":"Niimi","year":"2005","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2019.02.021_bib26","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1056\/NEJM197903223001201","article-title":"Chronic cough as the sole presenting manifestation of bronchial asthma","volume":"300","author":"Corrao","year":"1979","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jaip.2019.02.021_bib27","first-page":"457","article-title":"Variant asthma","volume":"30","author":"Glauser","year":"1972","journal-title":"Ann Allergy"},{"key":"10.1016\/j.jaip.2019.02.021_bib28","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1183\/09031936.98.11051064","article-title":"Eosinophilic inflammation in cough variant asthma","volume":"11","author":"Niimi","year":"1998","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaip.2019.02.021_bib29","doi-asserted-by":"crossref","first-page":"47","DOI":"10.2174\/157339811794109327","article-title":"Cough and asthma","volume":"7","author":"Niimi","year":"2011","journal-title":"Curr Respir Med Rev"},{"key":"10.1016\/j.jaip.2019.02.021_bib30","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1136\/thorax.58.1.14","article-title":"Comparison of atopic cough with cough variant asthma: is atopic cough a precursor of asthma?","volume":"58","author":"Fujimura","year":"2003","journal-title":"Thorax"},{"key":"10.1016\/j.jaip.2019.02.021_bib31","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1034\/j.1399-3003.1999.14b11.x","article-title":"Development of wheezing in patients with cough variant asthma during an increase in airway responsiveness","volume":"14","author":"Koh","year":"1999","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaip.2019.02.021_bib32","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1080\/02770900500498477","article-title":"Prognosis of cough variant asthma: a retrospective analysis","volume":"43","author":"Matsumoto","year":"2006","journal-title":"J\u00a0Asthma"},{"key":"10.1016\/j.jaip.2019.02.021_bib33","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1159\/000087459","article-title":"Characteristics of patients with chronic cough who developed classic asthma during the course of cough variant asthma: a longitudinal study","volume":"72","author":"Nakajima","year":"2005","journal-title":"Respiration"},{"key":"10.1016\/j.jaip.2019.02.021_bib34","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1378\/chest.10-0132","article-title":"Inflammatory subtypes in cough-variant asthma: association with maintenance doses of inhaled corticosteroids","volume":"138","author":"Matsuoka","year":"2010","journal-title":"Chest"},{"key":"10.1016\/j.jaip.2019.02.021_bib35","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/j.jaci.2016.04.045","article-title":"Capsaicin-evoked cough responses in asthmatic patients: evidence for airway neuronal dysfunction","volume":"139","author":"Satia","year":"2017","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2019.02.021_bib36","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1136\/thoraxjnl-2016-209625","article-title":"The interaction between bronchoconstriction and cough in asthma","volume":"72","author":"Satia","year":"2017","journal-title":"Thorax"},{"key":"10.1016\/j.jaip.2019.02.021_bib37","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/j.jaci.2008.08.029","article-title":"A\u00a0comparison of objective and subjective measures of cough in asthma","volume":"122","author":"Marsden","year":"2008","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2019.02.021_bib38","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1183\/09031936.00101307","article-title":"How to quantify coughing: correlations with quality of life in chronic cough","volume":"32","author":"Kelsall","year":"2008","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaip.2019.02.021_bib39","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1183\/09031936.98.11030599","article-title":"An undetected burden of asthma in Italy: the relationship between clinical and epidemiological diagnosis of asthma","volume":"11","author":"de Marco","year":"1998","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaip.2019.02.021_bib40","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1136\/thorax.56.5.406","article-title":"Continuing the debate about measuring asthma in population studies","volume":"56","author":"Peat","year":"2001","journal-title":"Thorax"},{"key":"10.1016\/j.jaip.2019.02.021_bib41","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1378\/chest.104.2.600","article-title":"Asthma and asthma-like symptoms in adults assessed by questionnaires: a literature review","volume":"104","author":"Toren","year":"1993","journal-title":"Chest"}],"container-title":["The Journal of Allergy and Clinical Immunology: In Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213219819301977?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213219819301977?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T05:21:36Z","timestamp":1761974496000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213219819301977"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":40,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["S2213219819301977"],"URL":"https:\/\/doi.org\/10.1016\/j.jaip.2019.02.021","relation":{},"ISSN":["2213-2198"],"issn-type":[{"value":"2213-2198","type":"print"}],"subject":[],"published":{"date-parts":[[2019,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Role and Impact of Chronic Cough in Individuals with Asthma From the General Population","name":"articletitle","label":"Article Title"},{"value":"The Journal of Allergy and Clinical Immunology: In Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaip.2019.02.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 American Academy of Allergy, Asthma & Immunology","name":"copyright","label":"Copyright"}]}}