{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T17:02:12Z","timestamp":1773162132349,"version":"3.50.1"},"reference-count":23,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["1P50GM115305-01"],"award-info":[{"award-number":["1P50GM115305-01"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R21AI139021"],"award-info":[{"award-number":["R21AI139021"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R34AI136815"],"award-info":[{"award-number":["R34AI136815"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012128","name":"Austin Medical Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012128","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["GNT 1116876"],"award-info":[{"award-number":["GNT 1116876"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["GNT 1139902"],"award-info":[{"award-number":["GNT 1139902"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaci-inpractice.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Allergy and Clinical Immunology: In Practice"],"published-print":{"date-parts":[[2019,11]]},"DOI":"10.1016\/j.jaip.2019.07.013","type":"journal-article","created":{"date-parts":[[2019,11,6]],"date-time":"2019-11-06T04:14:04Z","timestamp":1573013644000},"page":"2854-2856","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Associated with Carbonic Anhydrase Inhibitors: Epidemiology, Genetics, and Insights into Mechanisms"],"prefix":"10.1016","volume":"7","author":[{"given":"Jason A.","family":"Trubiano","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David A.","family":"Ostrov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth J.","family":"Phillips","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaip.2019.07.013_bib1","doi-asserted-by":"crossref","first-page":"2851","DOI":"10.1016\/j.jaip.2019.05.010","article-title":"Carbonic anhydrase inhibitor-induced Stevens-Johnson syndrome\/toxic epidermal necrolysis leads to extensive cutaneous involvement","volume":"7","author":"Kim","year":"2019","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2019.07.013_bib2","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1001\/archopht.116.1.117","article-title":"Methazolamide-induced Stevens-Johnson syndrome: a warning!","volume":"116","author":"Cotter","year":"1998","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.jaip.2019.07.013_bib3","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1016\/S0161-6420(95)30810-X","article-title":"Stevens-Johnson syndrome associated with methazolamide treatment reported in two Japanese-American women","volume":"102","author":"Flach","year":"1995","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jaip.2019.07.013_bib4","first-page":"101","article-title":"Stevens-Johnson syndrome due to Diamox","volume":"29","author":"Sud","year":"1981","journal-title":"Indian J Ophthalmol"},{"key":"10.1016\/j.jaip.2019.07.013_bib5","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1159\/000350939","article-title":"Cutaneous adverse drug reaction to oral acetazolamide and skin tests","volume":"226","author":"Jachiet","year":"2013","journal-title":"Dermatology"},{"key":"10.1016\/j.jaip.2019.07.013_bib6","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1038\/clpt.2009.252","article-title":"ALDEN, an algorithm for assessment of drug causality in Stevens-Johnson Syndrome and toxic epidermal necrolysis: comparison with case-control analysis","volume":"88","author":"Sassolas","year":"2010","journal-title":"Clin Pharmacol Ther"},{"key":"10.1016\/j.jaip.2019.07.013_bib7","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1007\/s00228-019-02670-9","article-title":"Adverse drug reaction causality assessment tools for drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: room for improvement","volume":"75","author":"Goldman","year":"2019","journal-title":"Eur J Clin Pharmacol"},{"key":"10.1016\/j.jaip.2019.07.013_bib8","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1016\/j.jaip.2016.04.026","article-title":"A\u00a0comparative analysis between antibiotic- and nonantibiotic-associated delayed cutaneous adverse drug reactions","volume":"4","author":"Trubiano","year":"2016","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2019.07.013_bib9","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1093\/cid\/ciu126","article-title":"Severe cutaneous adverse reactions related to systemic antibiotics","volume":"58","author":"Lin","year":"2014","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jaip.2019.07.013_bib10","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S0140-6736(18)32218-9","article-title":"Antibiotic allergy","volume":"393","author":"Blumenthal","year":"2019","journal-title":"Lancet"},{"key":"10.1016\/j.jaip.2019.07.013_bib11","series-title":"Clinical aspects of immunology","article-title":"The classification of allergic reactions underlying disease","author":"Gell","year":"1963"},{"key":"10.1016\/j.jaip.2019.07.013_bib12","doi-asserted-by":"crossref","first-page":"e214","DOI":"10.1016\/j.jaad.2014.07.013","article-title":"Toxic epidermal necrolysis in the absence of circulating T cells: a possible role for resident memory T cells","volume":"71","author":"Iriki","year":"2014","journal-title":"J\u00a0Am Acad Dermatol"},{"key":"10.1016\/j.jaip.2019.07.013_bib13","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1111\/cea.12184","article-title":"Allopurinol hypersensitivity is primarily mediated by dose-dependent oxypurinol-specific T cell response","volume":"43","author":"Yun","year":"2013","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaip.2019.07.013_bib14","doi-asserted-by":"crossref","first-page":"e0117160","DOI":"10.1371\/journal.pone.0117160","article-title":"Abacavir-reactive memory T cells are present in drug naive individuals","volume":"10","author":"Lucas","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.jaip.2019.07.013_bib15","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/tan.13183","article-title":"HLAs: key regulators of T-cell-mediated drug hypersensitivity","volume":"91","author":"Redwood","year":"2018","journal-title":"HLA"},{"key":"10.1016\/j.jaip.2019.07.013_bib16","doi-asserted-by":"crossref","first-page":"879","DOI":"10.2217\/pgs.10.54","article-title":"HLA-B*5901 is strongly associated with methazolamide-induced Stevens-Johnson syndrome\/toxic epidermal necrolysis","volume":"11","author":"Kim","year":"2010","journal-title":"Pharmacogenomics"},{"key":"10.1016\/j.jaip.2019.07.013_bib17","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/tpj.2015.25","article-title":"HLA-B*59:01: a marker for Stevens-Johnson syndrome\/toxic epidermal necrolysis caused by methazolamide in Han Chinese","volume":"16","author":"Yang","year":"2016","journal-title":"Pharmacogenomics J"},{"key":"10.1016\/j.jaip.2019.07.013_bib18","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1038\/s41397-018-0052-2","article-title":"Association between HLA-B*5901 and methazolamide-induced Stevens-Johnson syndrome\/toxic epidermal necrolysis: a systematic review and meta-analysis","volume":"19","author":"Tangamornsuksan","year":"2019","journal-title":"Pharmacogenomics J"},{"key":"10.1016\/j.jaip.2019.07.013_bib19","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1111\/j.1346-8138.2010.00921.x","article-title":"Stevens-Johnson syndrome induced by acetazolamide","volume":"38","author":"Her","year":"2011","journal-title":"J\u00a0Dermatol"},{"key":"10.1016\/j.jaip.2019.07.013_bib20","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.jaip.2017.01.025","article-title":"Severe delayed cutaneous and systemic reactions to drugs: a global perspective on the science and art of current practice","volume":"5","author":"Peter","year":"2017","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2019.07.013_bib21","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1002\/cpt.890","article-title":"Research directions in genetic predispositions to Stevens-Johnson syndrome\/toxic epidermal necrolysis","volume":"103","author":"Manolio","year":"2018","journal-title":"Clin Pharmacol Ther"},{"key":"10.1016\/j.jaip.2019.07.013_bib22","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.jaci.2019.01.045","article-title":"HLA-A*32:01 is strongly associated with vancomycin-induced drug reaction with eosinophilia and systemic symptoms","volume":"144","author":"Konvinse","year":"2019","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2019.07.013_bib23","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.jaip.2017.11.023","article-title":"SJS\/TEN 2017: building multidisciplinary networks to drive science and translation","volume":"6","author":"White","year":"2018","journal-title":"J\u00a0Allergy Clin Immunol Pract"}],"container-title":["The Journal of Allergy and Clinical Immunology: In Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213219819306300?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213219819306300?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T05:20:48Z","timestamp":1761974448000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213219819306300"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":23,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,11]]}},"alternative-id":["S2213219819306300"],"URL":"https:\/\/doi.org\/10.1016\/j.jaip.2019.07.013","relation":{},"ISSN":["2213-2198"],"issn-type":[{"value":"2213-2198","type":"print"}],"subject":[],"published":{"date-parts":[[2019,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Associated with Carbonic Anhydrase Inhibitors: Epidemiology, Genetics, and Insights into Mechanisms","name":"articletitle","label":"Article Title"},{"value":"The Journal of Allergy and Clinical Immunology: In Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaip.2019.07.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.jaip.2019.05.010","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 American Academy of Allergy, Asthma & Immunology","name":"copyright","label":"Copyright"}]}}