{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T19:02:34Z","timestamp":1790622154986,"version":"4.1.0"},"reference-count":40,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,8,5]],"date-time":"2022-08-05T00:00:00Z","timestamp":1659657600000},"content-version":"am","delay-in-days":369,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100002738","name":"Assistance Publique Hopitaux de Paris","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002738","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaci-inpractice.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Allergy and Clinical Immunology: In Practice"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1016\/j.jaip.2021.02.060","type":"journal-article","created":{"date-parts":[[2021,3,20]],"date-time":"2021-03-20T20:26:15Z","timestamp":1616271975000},"page":"3041-3050","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":44,"title":["DRESS and AGEP Reactions to Iodinated Contrast Media: A French Case Series"],"prefix":"10.1016","volume":"9","author":[{"given":"Ang\u00e8le","family":"Soria","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuelle","family":"Amsler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Bernier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigitte","family":"Milpied","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"T\u00e9tart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9cile","family":"Morice","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Dezoteux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Christine","family":"Ferrier-Le Bouedec","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annick","family":"Barbaud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delphine","family":"Staumont-Sall\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haudrey","family":"Assier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaip.2021.02.060_bib1","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1111\/j.1365-2133.2006.07284.x","article-title":"Variability in the clinical pattern of cutaneous side-effects of drugs with systemic symptoms: does a DRESS syndrome really exist?","volume":"155","author":"Peyri\u00e8re","year":"2006","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaip.2021.02.060_bib2","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1111\/j.1365-2133.2006.07704.x","article-title":"Variability in the clinical pattern of cutaneous side-effects of drugs with systemic symptoms: does a DRESS syndrome really exist?","volume":"156","author":"Kardaun","year":"2007","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaip.2021.02.060_bib3","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/j.jaad.2015.07.017","article-title":"Acute generalized exanthematous pustulosis (AGEP): a review and update","volume":"73","author":"Szatkowski","year":"2015","journal-title":"J\u00a0Am Acad Dermatol"},{"key":"10.1016\/j.jaip.2021.02.060_bib4","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1034\/j.1600-0560.2001.028003113.x","article-title":"Acute generalized exanthematous pustulosis (AGEP)\u2014a clinical reaction pattern","volume":"28","author":"Sidoroff","year":"2001","journal-title":"J\u00a0Cutan Pathol"},{"key":"10.1016\/j.jaip.2021.02.060_bib5","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1111\/ced.13991","article-title":"Contrast media and cutaneous reactions. Part 2: delayed hypersensitivity reactions to iodinated contrast media","volume":"44","author":"Tasker","year":"2019","journal-title":"Clin Exp Dermatol"},{"key":"10.1016\/j.jaip.2021.02.060_bib6","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.amjmed.2011.01.017","article-title":"The DRESS syndrome: a literature review","volume":"124","author":"Cacoub","year":"2011","journal-title":"Am J Med"},{"key":"10.1016\/j.jaip.2021.02.060_bib7","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.jaip.2018.08.013","article-title":"Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome identified in the Electronic Health Record Allergy Module","volume":"7","author":"Wolfson","year":"2019","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2021.02.060_bib8","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1111\/j.1365-2133.2007.08156.x","article-title":"Risk factors for acute generalized exanthematous pustulosis (AGEP)-results of a multinational case-control study (EuroSCAR)","volume":"157","author":"Sidoroff","year":"2007","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaip.2021.02.060_bib9","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1111\/bjd.12502","article-title":"Systemic involvement of acute generalized exanthematous pustulosis: a retrospective study on 58 patients","volume":"169","author":"Hotz","year":"2013","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaip.2021.02.060_bib10","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1007\/s003300000543","article-title":"Delayed allergy-like reactions to x-ray contrast media: mechanistic considerations","volume":"10","author":"Christiansen","year":"2000","journal-title":"Eur Radiol"},{"key":"10.1016\/j.jaip.2021.02.060_bib11","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1148\/radiol.10091848","article-title":"Delayed adverse reaction to contrast-enhanced CT: a prospective single-center study comparison to control group without enhancement","volume":"255","author":"Loh","year":"2010","journal-title":"Radiology"},{"key":"10.1016\/j.jaip.2021.02.060_bib12","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.iac.2009.04.001","article-title":"Immediate and delayed reactions to radiocontrast media: is there an allergic mechanism?","volume":"29","author":"Brockow","year":"2009","journal-title":"Immunol Allergy Clin North Am"},{"key":"10.1016\/j.jaip.2021.02.060_bib13","series-title":"Allergy","article-title":"Practice parameters for diagnosing and managing iodinated contrast media hypersensitivity","author":"Torres","year":"2021"},{"key":"10.1016\/j.jaip.2021.02.060_bib14","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1111\/j.1398-9995.2012.02840.x","article-title":"Diagnostic evaluation of patients with nonimmediate cutaneous hypersensitivity reactions to iodinated contrast media","volume":"67","author":"Torres","year":"2012","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2021.02.060_bib15","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1111\/all.12142","article-title":"Skin test concentrations for systemically administered drugs\u2014an ENDA\/EAACI Drug Allergy Interest Group position paper","volume":"68","author":"Brockow","year":"2013","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2021.02.060_bib16","series-title":"Patch Testing and Prick Testing: A Practical Guide Official Publication of the ICDRG","first-page":"254","author":"Lachapelle","year":"2019"},{"key":"10.1016\/j.jaip.2021.02.060_bib17","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.jaci.2015.07.035","article-title":"Analysis of cross-reactivity among radiocontrast media in 97 hypersensitivity reactions","volume":"137","author":"Lerondeau","year":"2016","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.02.060_bib18","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1016\/j.jaip.2017.10.040","article-title":"Skin testing for suspected iodinated contrast media hypersensitivity","volume":"6","author":"Schrijvers","year":"2018","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2021.02.060_bib19","first-page":"66","article-title":"First case report of acute generalized exanthematous pustulosis due to intravenous iopromide","volume":"24","author":"Bavbek","year":"2014","journal-title":"J\u00a0Investig Allergol Clin Immunol"},{"key":"10.1016\/j.jaip.2021.02.060_bib20","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.ejrad.2008.06.010","article-title":"Radiocontrast media-associated exanthema: identification of cross-reactivity and tolerability by allergologic testing","volume":"72","author":"Seitz","year":"2009","journal-title":"Eur J Radiol"},{"key":"10.1016\/j.jaip.2021.02.060_bib21","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/j.jaad.2019.09.036","article-title":"Drug reaction with eosinophilia and systemic symptoms may occur within 2 weeks of drug exposure: a retrospective study","volume":"82","author":"Soria","year":"2020","journal-title":"J\u00a0Am Acad Dermatol"},{"key":"10.1016\/j.jaip.2021.02.060_bib22","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1111\/bjd.12501","article-title":"Drug reaction with eosinophilia and systemic symptoms (DRESS): an original multisystem adverse drug reaction. Results from the prospective RegiSCAR study","volume":"169","author":"Kardaun","year":"2013","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaip.2021.02.060_bib23","doi-asserted-by":"crossref","first-page":"e178","DOI":"10.1111\/jdv.16139","article-title":"Cutaneous tests and interest of iobitridol in non-immediate hypersensitivity to contrast media: a case series of 43 patients","volume":"34","author":"Gaudin","year":"2020","journal-title":"J\u00a0Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.jaip.2021.02.060_bib24","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1001\/archdermatol.2010.198","article-title":"Drug reaction with eosinophilia and systemic symptoms: a retrospective study of 60 cases","volume":"146","author":"Chen","year":"2010","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jaip.2021.02.060_bib25","doi-asserted-by":"crossref","first-page":"2199","DOI":"10.1111\/jdv.13212","article-title":"Drug reaction with eosinophilia and systemic symptoms (DRESS): clinicopathological study of 45 cases","volume":"29","author":"Skowron","year":"2015","journal-title":"J\u00a0Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.jaip.2021.02.060_bib26","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1111\/cod.12724","article-title":"Acute generalized exanthematous pustulosis caused by an iodinated contrast radiocontrast medium for computed tomography arthrography of the knee","volume":"76","author":"Velter","year":"2017","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.jaip.2021.02.060_bib27","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1001\/archdermatol.2009.100","article-title":"Ioversol-induced acute generalized exanthematous pustulosis: a case report","volume":"145","author":"Hammerbeck","year":"2009","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jaip.2021.02.060_bib28","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.anai.2010.10.005","article-title":"Acute generalized exanthematous pustulosis caused by radiocontrast media","volume":"105","author":"Kim","year":"2010","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.jaip.2021.02.060_bib29","doi-asserted-by":"crossref","first-page":"344","DOI":"10.3109\/15569527.2014.961071","article-title":"Acute generalized exanthematous pustulosis induced by iodixanol (Visipaque): a serious reaction to a commonly used drug","volume":"34","author":"Ozturk","year":"2015","journal-title":"Cutan Ocul Toxicol"},{"key":"10.1016\/j.jaip.2021.02.060_bib30","first-page":"601","article-title":"Case of the month. Acute generalized exanthematous pustulosis due to an iodinated contrast radiodiagnostic agent [in French]","volume":"64","author":"Paquet","year":"2009","journal-title":"Rev Med Liege"},{"key":"10.1016\/j.jaip.2021.02.060_bib31","doi-asserted-by":"crossref","first-page":"W198","DOI":"10.2214\/AJR.05.0317","article-title":"Acute generalized exanthematous pustulosis as a delayed dermatotoxic reaction to IV-administered nonionic contrast media","volume":"187","author":"Peterson","year":"2006","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.jaip.2021.02.060_bib32","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.anai.2010.06.018","article-title":"Acute generalized exanthematous pustulosis: the first pediatric case caused by a contrast agent","volume":"105","author":"Poliak","year":"2010","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.jaip.2021.02.060_bib33","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/S0151-9638(04)93772-6","article-title":"Acute generalized exanthematous pustulosis induced by iopamidol [in French]","volume":"131","author":"Belgod\u00e8re","year":"2004","journal-title":"Ann Dermatol Venereol"},{"key":"10.1016\/j.jaip.2021.02.060_bib34","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1111\/j.1346-8138.2003.tb00466.x","article-title":"A\u00a0case of acute generalized exanthematous pustulosis (AGEP) possibly induced by iohexol","volume":"30","author":"Atasoy","year":"2003","journal-title":"J\u00a0Dermatol"},{"key":"10.1016\/j.jaip.2021.02.060_bib35","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/j.jaip.2014.07.015","article-title":"Iodinated contrast media-induced acute generalized exanthematous pustulosis confirmed by delayed skin tests","volume":"2","author":"Grandvuillemin","year":"2014","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2021.02.060_bib36","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1111\/cod.13242","article-title":"Acute generalized exanthematous pustulosis induced by iomeprol with cross-reactivity to other iodinated contrast agents and mild reactions after rechallenge with iopromide and oral corticosteroid premedication","volume":"81","author":"Machet","year":"2019","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.jaip.2021.02.060_bib37","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1111\/bjd.17835","article-title":"Are drug intradermal tests dangerous to explore cross-reactivity and co-sensitization in DRESS?","volume":"181","author":"Soria","year":"2019","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaip.2021.02.060_bib38","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.annder.2012.03.017","article-title":"Does hypersensitivity to multiple drugs really exist? [in French]","volume":"139","author":"Studer","year":"2012","journal-title":"Ann Dermatol Venereol"},{"key":"10.1016\/j.jaip.2021.02.060_bib39","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1111\/bjd.12125","article-title":"A\u00a0multicentre study to determine the value and safety of drug patch tests for the three main classes of severe cutaneous adverse drug reactions","volume":"168","author":"Barbaud","year":"2013","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaip.2021.02.060_bib40","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1111\/cea.13380","article-title":"Can we allow a further intake of drugs poorly suspected as responsible in drug reaction with eosinophilia and systemic symptoms (DRESS)? A study of practice","volume":"49","author":"Desroche","year":"2019","journal-title":"Clin Exp Allergy"}],"container-title":["The Journal of Allergy and Clinical Immunology: In Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213219821003184?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213219821003184?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T05:27:54Z","timestamp":1761974874000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213219821003184"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":40,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["S2213219821003184"],"URL":"https:\/\/doi.org\/10.1016\/j.jaip.2021.02.060","relation":{},"ISSN":["2213-2198"],"issn-type":[{"value":"2213-2198","type":"print"}],"subject":[],"published":{"date-parts":[[2021,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"DRESS and AGEP Reactions to Iodinated Contrast Media: A French Case Series","name":"articletitle","label":"Article Title"},{"value":"The Journal of Allergy and Clinical Immunology: In Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaip.2021.02.060","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 American Academy of Allergy, Asthma & Immunology","name":"copyright","label":"Copyright"}]}}