{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:17:56Z","timestamp":1791231476473,"version":"4.1.0"},"reference-count":208,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100002590","name":"American Lung Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002590","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004339","name":"Sanofi","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004339","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006259","name":"Teva Pharmaceutical Industries","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006259","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004328","name":"Genentech","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004328","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009857","name":"Regeneron Pharmaceuticals","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009857","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004330","name":"GlaxoSmithKline","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004330","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005612","name":"Shionogi","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005612","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001003","name":"Boehringer Ingelheim","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001003","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004336","name":"Novartis","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004336","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004334","name":"Merck","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004334","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaci-inpractice.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Allergy and Clinical Immunology: In Practice"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1016\/j.jaip.2021.11.016","type":"journal-article","created":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T12:20:30Z","timestamp":1638361230000},"page":"397-408","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"title":["The Role of Comorbidities in Difficult-to-Control Asthma in Adults and Children"],"prefix":"10.1016","volume":"10","author":[{"given":"Jonathan M.","family":"Gaffin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Castro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonard B.","family":"Bacharier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne L.","family":"Fuhlbrigge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaip.2021.11.016_bib1","doi-asserted-by":"crossref","first-page":"S781","DOI":"10.1016\/S0091-6749(97)70127-1","article-title":"Allergic rhinitis and asthma: how important is the link?","volume":"99","author":"Corren","year":"1997","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib2","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1067\/mai.2002.121701","article-title":"Rhinitis as an independent risk factor for adult-onset asthma","volume":"109","author":"Guerra","year":"2002","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib3","doi-asserted-by":"crossref","first-page":"185","DOI":"10.2500\/108854198778557836","article-title":"Co-existence of asthma and allergic rhinitis: a 23-year follow-up study of college students","volume":"19","author":"Greisner","year":"1998","journal-title":"Allergy Asthma Proc"},{"key":"10.1016\/j.jaip.2021.11.016_bib4","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1378\/chest.115.4.928","article-title":"Incidence and prevalence of asthma among adult Finnish men and women of the Finnish Twin Cohort from 1975 to 1990, and their relation to hay fever and chronic bronchitis","volume":"115","author":"Huovinen","year":"1999","journal-title":"Chest"},{"key":"10.1016\/j.jaip.2021.11.016_bib5","doi-asserted-by":"crossref","first-page":"187","DOI":"10.2500\/ajra.2012.26.3762","article-title":"The united allergic airway: connections between allergic rhinitis, asthma, and chronic sinusitis","volume":"26","author":"Feng","year":"2012","journal-title":"Am J Rhinol Allergy"},{"key":"10.1016\/j.jaip.2021.11.016_bib6","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1016\/j.jaci.2018.07.041","article-title":"Rhinitis in children and adolescents with asthma: ubiquitous, difficult to control, and associated with asthma outcomes","volume":"143","author":"Togias","year":"2019","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib7","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1186\/s12887-015-0481-x","article-title":"Characteristics and severity of asthma in children with and without atopic conditions: a cross-sectional study","volume":"15","author":"Arabkhazaeli","year":"2015","journal-title":"BMC Pediatr"},{"key":"10.1016\/j.jaip.2021.11.016_bib8","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1016\/j.jaci.2016.06.059","article-title":"Distinguishing characteristics of difficult-to-control asthma in inner-city children and adolescents","volume":"138","author":"Pongracic","year":"2016","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib9","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1111\/j.1365-2222.2004.01969.x","article-title":"Characteristics of patients with seasonal allergic rhinitis and concomitant asthma","volume":"34","author":"Bousquet","year":"2004","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaip.2021.11.016_bib10","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/S0091-6749(99)70525-7","article-title":"Allergic rhinitis in Rochester, Minnesota residents with asthma: frequency and impact on health care charges","volume":"103","author":"Yawn","year":"1999","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib11","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1081\/JAS-120026069","article-title":"Allergic rhinitis: a potential cause of increased asthma medication use, costs, and morbidity","volume":"41","author":"Halpern","year":"2004","journal-title":"J\u00a0Asthma"},{"key":"10.1016\/j.jaip.2021.11.016_bib12","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/j.jaci.2020.07.007","article-title":"Rhinitis 2020: a practice parameter update","volume":"146","author":"Dykewicz","year":"2020","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib13","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1111\/all.12124","article-title":"Impact of intranasal corticosteroids on asthma outcomes in allergic rhinitis: a meta-analysis","volume":"68","author":"Lohia","year":"2013","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2021.11.016_bib14","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/j.jaci.2014.06.038","article-title":"Efficacy of nasal mometasone for the treatment of chronic sinonasal disease in patients with inadequately controlled asthma","volume":"135","author":"Dixon","year":"2015","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4193\/Rhino12.000","article-title":"EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists","volume":"50","author":"Fokkens","year":"2012","journal-title":"Rhinology"},{"key":"10.1016\/j.jaip.2021.11.016_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4193\/Rhin20.401","article-title":"European position paper on rhinosinusitis and nasal polyps 2020","volume":"58","author":"Fokkens","year":"2020","journal-title":"Rhinology"},{"key":"10.1016\/j.jaip.2021.11.016_bib17","first-page":"S1","article-title":"Clinical practice guideline (update): adult sinusitis","volume":"152","author":"Rosenfeld","year":"2015","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.jaip.2021.11.016_bib18","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1378\/chest.130.2.429","article-title":"Allergic rhinitis and sinusitis in asthma: differential effects on symptoms and pulmonary function","volume":"130","author":"Dixon","year":"2006","journal-title":"Chest"},{"key":"10.1016\/j.jaip.2021.11.016_bib19","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1164\/rccm.201602-0419OC","article-title":"Inflammatory and comorbid features of patients with severe asthma and frequent exacerbations","volume":"195","author":"Denlinger","year":"2017","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib20","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1111\/resp.12838","article-title":"Comorbidities in difficult asthma are independent risk factors for frequent exacerbations, poor control and diminished quality of life","volume":"21","author":"Tay","year":"2016","journal-title":"Respirology"},{"key":"10.1016\/j.jaip.2021.11.016_bib21","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.jaci.2006.07.024","article-title":"Clinical and pathologic perspectives on aspirin sensitivity and asthma","volume":"118","author":"Stevenson","year":"2006","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib22","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/j.jaci.2020.10.043","volume":"147","author":"Stevens","year":"2021","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib23","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1016\/S0140-6736(19)31881-1","article-title":"Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials","volume":"394","author":"Bachert","year":"2019","journal-title":"Lancet"},{"key":"10.1016\/j.jaip.2021.11.016_bib24","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.jaci.2020.05.032","article-title":"Efficacy and safety of omalizumab in nasal polyposis: 2 randomized phase 3 trials","volume":"146","author":"Gevaert","year":"2020","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib25","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.jaci.2013.04.005","article-title":"Thymic stromal lymphopoietin activity is increased in nasal polyps of patients with chronic rhinosinusitis","volume":"132","author":"Nagarkar","year":"2013","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib26","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.otc.2021.04.007","article-title":"Current evidence for biologic therapy in chronic rhinosinusitis with nasal polyposis","volume":"54","author":"Ramaswamy","year":"2021","journal-title":"Otolaryngol Clin North Am"},{"key":"10.1016\/j.jaip.2021.11.016_bib27","doi-asserted-by":"crossref","first-page":"2312","DOI":"10.1111\/all.13875","article-title":"EUFOREA consensus on biologics for CRSwNP with or without asthma","volume":"74","author":"Fokkens","year":"2019","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2021.11.016_bib28","doi-asserted-by":"crossref","first-page":"197","DOI":"10.2500\/ajr.2008.22.3148","article-title":"Asthma outcomes after endoscopic sinus surgery in aspirin-tolerant versus aspirin-induced asthmatic patients","volume":"22","author":"Awad","year":"2008","journal-title":"Am J Rhinol"},{"key":"10.1016\/j.jaip.2021.11.016_bib29","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1002\/alr.21182","article-title":"A\u00a0systematic review and meta-analysis of asthma outcomes following endoscopic sinus surgery for chronic rhinosinusitis","volume":"3","author":"Vashishta","year":"2013","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2021.11.016_bib30","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1007\/s00405-019-05337-4","article-title":"The effects of endoscopic sinus surgery on pulmonary function in chronic rhinosinusitis patients with asthma: a systematic review and meta-analysis","volume":"276","author":"Cao","year":"2019","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"10.1016\/j.jaip.2021.11.016_bib31","doi-asserted-by":"crossref","first-page":"E26","DOI":"10.1002\/lary.28648","article-title":"Cost utility analysis of dupilumab versus endoscopic sinus surgery for chronic rhinosinusitis with nasal polyps","volume":"131","author":"Scangas","year":"2021","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jaip.2021.11.016_bib32","unstructured":"Centers for Disease Control and Prevention. CDC growth charts. Accessed October 28, 2021. https:\/\/www.cdc.gov\/growthcharts\/clinical_charts.htm"},{"key":"10.1016\/j.jaip.2021.11.016_bib33","doi-asserted-by":"crossref","first-page":"576858","DOI":"10.3389\/fped.2020.576858","article-title":"Bidirectional association between asthma and obesity during childhood and adolescence: a systematic review and meta-analysis","volume":"8","author":"Shan","year":"2020","journal-title":"Front Pediatr"},{"key":"10.1016\/j.jaip.2021.11.016_bib34","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1016\/j.jaip.2016.06.004","article-title":"Burden of obesity on pediatric inpatients with acute asthma exacerbation in the United States","volume":"4","author":"Okubo","year":"2016","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2021.11.016_bib35","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1164\/rccm.201211-2116OC","article-title":"Childhood obesity and asthma control in the GALA II and SAGE II studies","volume":"187","author":"Borrell","year":"2013","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib36","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/j.jaci.2006.11.007","article-title":"Excessive body weight is associated with additional loss of quality of life in children with asthma","volume":"119","author":"van Gent","year":"2007","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib37","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/j.jaci.2010.12.010","article-title":"Decreased response to inhaled steroids in overweight and obese asthmatic children","volume":"127","author":"Forno","year":"2011","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib38","article-title":"The association of co-morbid asthma and overweight\/obese status with healthcare utilization and caregiver perception of health in children 4-17 years, a NHANES study","author":"Hong","year":"2021","journal-title":"J Asthma"},{"key":"10.1016\/j.jaip.2021.11.016_bib39","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1542\/hpeds.2015-0242","article-title":"Lack of recognition, diagnosis, and treatment of overweight\/obesity in children hospitalized for asthma","volume":"6","author":"Borgmeyer","year":"2016","journal-title":"Hosp Pediatr"},{"key":"10.1016\/j.jaip.2021.11.016_bib40","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1513\/AnnalsATS.201810-651SR","article-title":"Weight loss for children and adults with obesity and asthma. a systematic review of randomized controlled trials","volume":"16","author":"Okoniewski","year":"2019","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.jaip.2021.11.016_bib41","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1159\/000360398","article-title":"Normocaloric diet improves asthma-related quality of life in obese pubertal adolescents","volume":"163","author":"Luna-Pech","year":"2014","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib42","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0157158","article-title":"A\u00a0multifactorial weight reduction programme for children with overweight and asthma: a randomized controlled trial","volume":"11","author":"Willeboordse","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.jaip.2021.11.016_bib43","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1016\/j.jaci.2018.02.004","article-title":"Obesity and asthma","volume":"141","author":"Peters","year":"2018","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib44","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1136\/thx.54.5.396","article-title":"Birth weight, body mass index and asthma in young adults","volume":"54","author":"Shaheen","year":"1999","journal-title":"Thorax"},{"key":"10.1016\/j.jaip.2021.11.016_bib45","doi-asserted-by":"crossref","first-page":"2582","DOI":"10.1001\/archinte.159.21.2582","article-title":"Prospective study of body mass index, weight change, and risk of adult-onset asthma in women","volume":"159","author":"Camargo","year":"1999","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib46","doi-asserted-by":"crossref","first-page":"2045","DOI":"10.1164\/ajrccm.164.11.2004235","article-title":"Asthma is associated with weight gain in females but not males, independent of physical activity","volume":"164","author":"Beckett","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib47","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1093\/aje\/155.3.191","article-title":"Obesity may increase the incidence of asthma in women but not in men: longitudinal observations from the Canadian National Population Health Surveys","volume":"155","author":"Chen","year":"2002","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.jaip.2021.11.016_bib48","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1378\/chest.122.4.1256","article-title":"The relation of body mass index to asthma, chronic bronchitis, and emphysema","volume":"122","author":"Guerra","year":"2002","journal-title":"Chest"},{"key":"10.1016\/j.jaip.2021.11.016_bib49","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1183\/09031936.04.00088003","article-title":"Body mass index and asthma incidence among USA adults","volume":"24","author":"Ford","year":"2004","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaip.2021.11.016_bib50","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1164\/rccm.200611-1717OC","article-title":"Overweight, obesity, and incident asthma: a meta-analysis of prospective epidemiologic studies","volume":"175","author":"Beuther","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib51","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1164\/rccm.200711-1754OC","article-title":"Cluster analysis and clinical asthma phenotypes","volume":"178","author":"Haldar","year":"2008","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib52","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1016\/j.jaci.2016.08.048","article-title":"U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics","volume":"139","author":"Lefaudeux","year":"2017","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib53","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1164\/rccm.200906-0896OC","article-title":"Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program","volume":"181","author":"Moore","year":"2010","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib54","doi-asserted-by":"crossref","first-page":"S395","DOI":"10.1513\/AnnalsATS.201702-122AW","article-title":"Pathophysiology to phenotype in the asthma of obesity","volume":"14","author":"Bates","year":"2017","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.jaip.2021.11.016_bib55","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1111\/cea.12004","article-title":"Dietary restriction and exercise improve airway inflammation and clinical outcomes in overweight and obese asthma: a randomized trial","volume":"43","author":"Scott","year":"2013","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaip.2021.11.016_bib56","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1164\/rccm.201603-0446OC","article-title":"The role of exercise in a weight-loss program on clinical control in obese adults with asthma. A randomized controlled trial","volume":"195","author":"Freitas","year":"2017","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib57","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.1016\/j.jaip.2021.01.016","article-title":"A\u00a0practical approach to assist asthmatics to lose weight","volume":"9","author":"Kolinsky","year":"2021","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2021.11.016_bib58","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1381\/096089299765552981","article-title":"Marked improvement in asthma after Lap-Band surgery for morbid obesity","volume":"9","author":"Dixon","year":"1999","journal-title":"Obes Surg"},{"key":"10.1016\/j.jaip.2021.11.016_bib59","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1381\/096089200321594291","article-title":"Improvement in co-morbidities following weight loss from gastric bypass surgery","volume":"10","author":"Dhabuwala","year":"2000","journal-title":"Obes Surg"},{"key":"10.1016\/j.jaip.2021.11.016_bib60","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1381\/096089293765559700","article-title":"Effect of surgically induced weight loss on asthma in the morbidly obese","volume":"3","author":"Macgregor","year":"1993","journal-title":"Obes Surg"},{"key":"10.1016\/j.jaip.2021.11.016_bib61","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0214730","article-title":"The impact of bariatric surgery on asthma control differs among obese individuals with reported prior or current asthma, with or without metabolic syndrome","volume":"14","author":"Forno","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.jaip.2021.11.016_bib62","doi-asserted-by":"crossref","first-page":"1602221","DOI":"10.1183\/13993003.02221-2016","article-title":"Inducible laryngeal obstruction: an official joint European Respiratory Society and European Laryngological Society statement","volume":"50","author":"Halvorsen","year":"2017","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaip.2021.11.016_bib63","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1183\/13993003.00160-2016","article-title":"Continuous laryngoscopy quantitates laryngeal behaviour in exercise and recovery","volume":"48","author":"Olin","year":"2016","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaip.2021.11.016_bib64","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.7205\/MILMED-D-13-00155","article-title":"Vocal cord dysfunction related to combat deployment","volume":"178","author":"Morris","year":"2013","journal-title":"Mil Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib65","doi-asserted-by":"crossref","first-page":"409","DOI":"10.3109\/02770909809048949","article-title":"Psychological and family characteristics of adolescents with vocal cord dysfunction","volume":"35","author":"Gavin","year":"1998","journal-title":"J\u00a0Asthma"},{"key":"10.1016\/j.jaip.2021.11.016_bib66","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1097\/MLG.0b013e31815ed13a","article-title":"Formal psychological testing in patients with paradoxical vocal fold dysfunction","volume":"118","author":"Husein","year":"2008","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jaip.2021.11.016_bib67","doi-asserted-by":"crossref","first-page":"2256","DOI":"10.1016\/j.jaip.2020.02.037","article-title":"Paradoxical vocal fold motion in difficult asthma is associated with dysfunctional breathing and preserved lung function","volume":"8","author":"Lee","year":"2020","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2021.11.016_bib68","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1111\/cea.13185","article-title":"Diagnosis of concomitant inducible laryngeal obstruction and asthma","volume":"48","author":"Lee","year":"2018","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaip.2021.11.016_bib69","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1164\/rccm.201010-1604OC","article-title":"Abnormal vocal cord function in difficult-to-treat asthma","volume":"184","author":"Low","year":"2011","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib70","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1111\/cea.12550","article-title":"The VCDQ\u2014a questionnaire for symptom monitoring in vocal cord dysfunction","volume":"45","author":"Fowler","year":"2015","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaip.2021.11.016_bib71","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.jaip.2013.09.002","article-title":"A\u00a0novel scoring system to distinguish vocal cord dysfunction from asthma","volume":"2","author":"Traister","year":"2014","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2021.11.016_bib72","first-page":"775","article-title":"Development and validation of the Dyspnea Index (DI): a severity index for upper airway-related dyspnea","volume":"28","author":"Gartner-Schmidt","year":"2014","journal-title":"J\u00a0Voice"},{"key":"10.1016\/j.jaip.2021.11.016_bib73","doi-asserted-by":"crossref","first-page":"306","DOI":"10.4104\/pcrj.2013.00067","article-title":"Can flow-volume loops be used to diagnose exercise induced laryngeal obstructions? A comparison study examining the accuracy and inter-rater agreement of flow volume loops as a diagnostic tool","volume":"22","author":"Christensen","year":"2013","journal-title":"Prim Care Respir J"},{"key":"10.1016\/j.jaip.2021.11.016_bib74","doi-asserted-by":"crossref","first-page":"379","DOI":"10.3389\/fped.2020.00379","article-title":"Pediatric dysfunctional breathing: proposed components, mechanisms, diagnosis, and management","volume":"8","author":"Barker","year":"2020","journal-title":"Front Pediatr"},{"key":"10.1016\/j.jaip.2021.11.016_bib75","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1002\/lary.26416","article-title":"Does treatment of paradoxical vocal fold movement disorder decrease asthma medication use?","volume":"127","author":"Kramer","year":"2017","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jaip.2021.11.016_bib76","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1002\/lary.29283","article-title":"Reduced asthma medication use after treatment of pediatric paradoxical vocal fold motion disorder","volume":"131","author":"Ivancic","year":"2021","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jaip.2021.11.016_bib77","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1016\/S1081-1206(10)61341-5","article-title":"Long-term outcome of vocal cord dysfunction","volume":"96","author":"Doshi","year":"2006","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib78","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1016\/j.ijporl.2015.04.044","article-title":"Office-based laryngeal injection of botulinum toxin for paradoxical vocal fold motion in a child","volume":"79","author":"Montojo","year":"2015","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"10.1016\/j.jaip.2021.11.016_bib79","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/j.ijporl.2013.12.037","article-title":"Periodic botulinum toxin injections for paradoxical vocal fold motion in a child with cerebral palsy: a case study","volume":"78","author":"Cheng","year":"2014","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"10.1016\/j.jaip.2021.11.016_bib80","first-page":"1152","article-title":"Surgical treatment is effective in severe cases of exercise-induced laryngeal obstruction: a follow-up study","volume":"135","author":"Norlander","year":"2015","journal-title":"Acta Otolaryngol"},{"key":"10.1016\/j.jaip.2021.11.016_bib81","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1183\/16000617.0088-2015","article-title":"Dysfunctional breathing: a review of the literature and proposal for classification","volume":"25","author":"Boulding","year":"2016","journal-title":"Eur Respir Rev"},{"key":"10.1016\/j.jaip.2021.11.016_bib82","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1016\/j.jaip.2018.11.037","article-title":"Factors associated with dysfunctional breathing in patients with difficult to treat asthma","volume":"7","author":"Denton","year":"2019","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2021.11.016_bib83","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0022-3999(85)90042-X","article-title":"Efficacy of Nijmegen Questionnaire in recognition of the hyperventilation syndrome","volume":"29","author":"van Dixhoorn","year":"1985","journal-title":"J\u00a0Psychosom Res"},{"key":"10.1016\/j.jaip.2021.11.016_bib84","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s10484-015-9316-7","article-title":"Reliability and determinants of Self-Evaluation of Breathing Questionnaire (SEBQ) score: a symptoms-based measure of dysfunctional breathing","volume":"41","author":"Mitchell","year":"2016","journal-title":"Appl Psychophysiol Biofeedback"},{"key":"10.1016\/j.jaip.2021.11.016_bib85","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1111\/all.13611","article-title":"Breathing pattern disorder in difficult asthma: characteristics and improvement in asthma control and quality of life after breathing re-training","volume":"74","author":"Denton","year":"2019","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2021.11.016_bib86","first-page":"83","article-title":"Sleep-disordered breathing in children with asthma: a systematic review on the impact of treatment","volume":"9","author":"Sanchez","year":"2016","journal-title":"J\u00a0Asthma Allergy"},{"key":"10.1016\/j.jaip.2021.11.016_bib87","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1080\/02770903.2020.1818775","article-title":"Pediatric sleep questionnaire predicts more severe sleep apnea in children with uncontrolled asthma","volume":"58","author":"Dooley","year":"2021","journal-title":"J\u00a0Asthma"},{"key":"10.1016\/j.jaip.2021.11.016_bib88","doi-asserted-by":"crossref","first-page":"3679","DOI":"10.1016\/j.jaip.2021.05.022","article-title":"Associations of snoring and asthma morbidity in the school inner-city asthma study","volume":"9","author":"Gunnlaugsson","year":"2021","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2021.11.016_bib89","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1001753","article-title":"Association of adenotonsillectomy with asthma outcomes in children: a longitudinal database analysis","volume":"11","author":"Bhattacharjee","year":"2014","journal-title":"PLoS Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib90","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1378\/chest.08-1273","article-title":"Predictors of habitual snoring and obstructive sleep apnea risk in patients with asthma","volume":"135","author":"Teodorescu","year":"2009","journal-title":"Chest"},{"key":"10.1016\/j.jaip.2021.11.016_bib91","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1378\/chest.130.6.1779","article-title":"Longitudinal study of risk factors for habitual snoring in a general adult population: the Busselton Health Study","volume":"130","author":"Knuiman","year":"2006","journal-title":"Chest"},{"key":"10.1016\/j.jaip.2021.11.016_bib92","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1001\/jama.2014.17822","article-title":"Association between asthma and risk of developing obstructive sleep apnea","volume":"313","author":"Teodorescu","year":"2015","journal-title":"JAMA"},{"key":"10.1016\/j.jaip.2021.11.016_bib93","article-title":"Risk of obstructive sleep apnea in adult patients with asthma: a population-based cohort study in Taiwan","volume":"10","author":"Shen","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.jaip.2021.11.016_bib94","doi-asserted-by":"crossref","first-page":"4088","DOI":"10.1038\/s41598-017-04446-6","article-title":"Association of obstructive sleep apnea with asthma: a meta-analysis","volume":"7","author":"Kong","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.jaip.2021.11.016_bib95","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/s12890-017-0398-2","article-title":"Obstructive sleep apnoea accelerates FEV(1) decline in asthmatic patients","volume":"17","author":"Wang","year":"2017","journal-title":"BMC Pulm Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib96","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.jaci.2009.05.016","article-title":"Prevalence of obstructive sleep apnea-hypopnea in severe versus moderate asthma","volume":"124","author":"Julien","year":"2009","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib97","doi-asserted-by":"crossref","first-page":"251567","DOI":"10.1155\/2013\/251567","article-title":"Asthma control and its relationship with obstructive sleep apnea (OSA) in older adults","volume":"2013","author":"Teodorescu","year":"2013","journal-title":"Sleep Disord"},{"key":"10.1016\/j.jaip.2021.11.016_bib98","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/j.jaip.2015.04.002","article-title":"Obstructive sleep apnea risk, asthma burden, and lower airway inflammation in adults in the Severe Asthma Research Program (SARP) II","volume":"3","author":"Teodorescu","year":"2015","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2021.11.016_bib99","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1016\/j.sleep.2007.06.010","article-title":"Findings of a Berlin Questionnaire survey: comparison between patients seen in an asthma clinic versus internal medicine clinic","volume":"9","author":"Auckley","year":"2008","journal-title":"Sleep Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib100","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.anai.2013.01.005","article-title":"Obstructive sleep apnea is associated with reduced quality of life in adult patients with asthma","volume":"110","author":"Kim","year":"2013","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib101","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.sleep.2016.06.013","article-title":"Impact of obstructive sleep apnea on severe asthma exacerbations","volume":"26","author":"Wang","year":"2016","journal-title":"Sleep Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib102","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1111\/all.13070","article-title":"Asthma outcomes improve with continuous positive airway pressure for obstructive sleep apnea","volume":"72","author":"Serrano-Pariente","year":"2017","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2021.11.016_bib103","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1007\/s11325-016-1340-1","article-title":"Long-term CPAP treatment improves asthma control in patients with asthma and obstructive sleep apnoea","volume":"20","author":"Kauppi","year":"2016","journal-title":"Sleep Breath"},{"key":"10.1016\/j.jaip.2021.11.016_bib104","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.rmed.2018.08.004","article-title":"Does continuous positive airway pressure (CPAP) treatment of obstructive sleep apnoea (OSA) improve asthma-related clinical outcomes in patients with co-existing conditions?\u2014A systematic review","volume":"143","author":"Davies","year":"2018","journal-title":"Respir Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib105","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1136\/archdischild-2017-312890","article-title":"Respiratory manifestations of gastro-oesophageal reflux in children","volume":"103","author":"de Benedictis","year":"2018","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.jaip.2021.11.016_bib106","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0889-8553(05)70366-6","article-title":"Typical and atypical presentations of gastroesophageal reflux disease. The role of esophageal testing in diagnosis and management","volume":"25","author":"Richter","year":"1996","journal-title":"Gastroenterol Clin North Am"},{"key":"10.1016\/j.jaip.2021.11.016_bib107","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1002\/j.1536-4801.1993.tb10966.x","article-title":"Gastroesophageal reflux and bronchial asthma: prevalence and effect of cisapride therapy","volume":"17","author":"Tucci","year":"1993","journal-title":"J\u00a0Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.jaip.2021.11.016_bib108","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1081\/JAS-120002194","article-title":"The pattern of gastroesophageal reflux in asthmatic children","volume":"39","author":"Cinquetti","year":"2002","journal-title":"J\u00a0Asthma"},{"key":"10.1016\/j.jaip.2021.11.016_bib109","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1007\/s12016-018-8701-4","article-title":"Impact of gastroesophageal reflux disease on mucosal immunity and atopic disorders","volume":"57","author":"Hait","year":"2019","journal-title":"Clin Rev Allergy Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib110","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1038\/ajg.2012.444","article-title":"Guidelines for the diagnosis and management of gastroesophageal reflux disease","volume":"108","author":"Katz","year":"2013","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.jaip.2021.11.016_bib111","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1097\/MPG.0000000000001889","article-title":"Pediatric gastroesophageal reflux clinical practice guidelines: joint recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition","volume":"66","author":"Rosen","year":"2018","journal-title":"J\u00a0Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.jaip.2021.11.016_bib112","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1001\/jama.2011.2035","article-title":"Lansoprazole for children with poorly controlled asthma: a randomized controlled trial","volume":"307","author":"Holbrook","year":"2012","journal-title":"JAMA"},{"key":"10.1016\/j.jaip.2021.11.016_bib113","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1378\/chest.11-0741","article-title":"Refractory asthma: importance of bronchoscopy to identify phenotypes and direct therapy","volume":"141","author":"Good","year":"2012","journal-title":"Chest"},{"key":"10.1016\/j.jaip.2021.11.016_bib114","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1056\/NEJMoa0806290","article-title":"Efficacy of esomeprazole for treatment of poorly controlled asthma","volume":"360","author":"Mastronarde","year":"2009","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib115","doi-asserted-by":"crossref","first-page":"707","DOI":"10.3109\/02770903.2011.601778","article-title":"Effects of obstructive sleep apnea and gastroesophageal reflux disease on asthma control in obesity","volume":"48","author":"Dixon","year":"2011","journal-title":"J\u00a0Asthma"},{"key":"10.1016\/j.jaip.2021.11.016_bib116","first-page":"CD001496","article-title":"Pharmacological and surgical interventions for the treatment of gastro-oesophageal reflux in adults and children with asthma","volume":"5","author":"Kopsaftis","year":"2021","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jaip.2021.11.016_bib117","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1183\/09031936.00138707","article-title":"Global strategy for asthma management and prevention: GINA executive summary","volume":"31","author":"Bateman","year":"2008","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaip.2021.11.016_bib118","doi-asserted-by":"crossref","first-page":"S94","DOI":"10.1016\/j.jaci.2007.09.029","article-title":"Expert panel report 3 (EPR-3): guidelines for the diagnosis and management of asthma-summary report 2007","volume":"120","year":"2007","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib119","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1097\/SLE.0b013e31825efb5b","article-title":"Effectiveness of laparoscopic total and partial fundoplication on extraesophageal manifestations of gastroesophageal reflux disease: a randomized study","volume":"22","author":"Koch","year":"2012","journal-title":"Surg Laparosc Endosc Percutan Tech"},{"key":"10.1016\/j.jaip.2021.11.016_bib120","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1007\/s10880-017-9528-5","article-title":"The interaction between asthma and anxiety: an interpretative phenomenological analysis of young people\u2019s experiences","volume":"25","author":"Pateraki","year":"2018","journal-title":"J Clin Psychol Med Settings"},{"key":"10.1016\/j.jaip.2021.11.016_bib121","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1164\/rccm.201501-0037OC","article-title":"Stress and bronchodilator response in children with asthma","volume":"192","author":"Brehm","year":"2015","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib122","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1164\/rccm.201606-1213PP","article-title":"Predicting severe asthma exacerbations in children","volume":"195","author":"Puranik","year":"2017","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib123","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.bbi.2016.03.024","article-title":"Mind-body interactions in the regulation of airway inflammation in asthma: a PET study of acute and chronic stress","volume":"58","author":"Rosenkranz","year":"2016","journal-title":"Brain Behav Immun"},{"key":"10.1016\/j.jaip.2021.11.016_bib124","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1016\/j.jaci.2014.07.005","article-title":"Stress and asthma: novel insights on genetic, epigenetic, and immunologic mechanisms","volume":"134","author":"Rosenberg","year":"2014","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib125","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.jadohealth.2007.05.023","article-title":"The prevalence of DSM-IV anxiety and depressive disorders in youth with asthma compared with controls","volume":"41","author":"Katon","year":"2007","journal-title":"J\u00a0Adolesc Health"},{"key":"10.1016\/j.jaip.2021.11.016_bib126","first-page":"115","article-title":"Asthma and mood disorders","volume":"1","author":"Kewalramani","year":"2008","journal-title":"Int J Child Health Hum Dev"},{"key":"10.1016\/j.jaip.2021.11.016_bib127","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1080\/02770900500264770","article-title":"Prevalence of probable mental disorders among pediatric asthma patients in an inner-city clinic","volume":"42","author":"Goodwin","year":"2005","journal-title":"J\u00a0Asthma"},{"key":"10.1016\/j.jaip.2021.11.016_bib128","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1542\/peds.2006-0249","article-title":"Asthma symptom burden: relationship to asthma severity and anxiety and depression symptoms","volume":"118","author":"Richardson","year":"2006","journal-title":"Pediatrics"},{"key":"10.1016\/j.jaip.2021.11.016_bib129","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1016\/j.jaip.2020.12.060","article-title":"High levels of anxiety during the COVID-19 pandemic as a risk factor of clinical worsening in patients with severe asthma","volume":"9","author":"Lacwik","year":"2021","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2021.11.016_bib130","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1002\/ppul.25120","article-title":"Asthma control and psychological health in pediatric severe asthma","volume":"56","author":"Griffiths","year":"2021","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.jaip.2021.11.016_bib131","doi-asserted-by":"crossref","first-page":"210","DOI":"10.2500\/aap.2020.41.200017","article-title":"Association between asthma symptom scores and perceived stress and trait anxiety in adolescents with asthma","volume":"41","author":"Luria","year":"2020","journal-title":"Allergy Asthma Proc"},{"key":"10.1016\/j.jaip.2021.11.016_bib132","doi-asserted-by":"crossref","first-page":"2908","DOI":"10.1002\/ppul.25061","article-title":"Greater length of stay and hospital charges for severe asthma in children with depression or anxiety","volume":"55","author":"Munoz","year":"2020","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.jaip.2021.11.016_bib133","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2019-0856","article-title":"Depression, anxiety, and emergency department use for asthma","volume":"144","author":"Bardach","year":"2019","journal-title":"Pediatrics"},{"key":"10.1016\/j.jaip.2021.11.016_bib134","doi-asserted-by":"crossref","first-page":"106187","DOI":"10.1016\/j.rmed.2020.106187","article-title":"Relationship between pediatric asthma and psychosocial status of caregivers","volume":"174","author":"Morillo-Vanegas","year":"2020","journal-title":"Respir Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib135","first-page":"256","article-title":"Social disadvantage and asthma control in children","volume":"15","author":"Kopel","year":"2014","journal-title":"Paediatr Respir Rev"},{"key":"10.1016\/j.jaip.2021.11.016_bib136","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1001\/archpedi.155.3.347","article-title":"Maternal depressive symptoms and emergency department use among inner-city children with asthma","volume":"155","author":"Bartlett","year":"2001","journal-title":"Arch Pediatr Adolesc Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib137","doi-asserted-by":"crossref","DOI":"10.4081\/monaldi.2019.1063","article-title":"Anxiety and depression in adolescents with asthma and in their parents: a study in clinical practice","volume":"89","author":"Licari","year":"2019","journal-title":"Monaldi Arch Chest Dis"},{"key":"10.1016\/j.jaip.2021.11.016_bib138","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1542\/peds.113.2.229","article-title":"Maternal depressive symptoms and adherence to therapy in inner-city children with asthma","volume":"113","author":"Bartlett","year":"2004","journal-title":"Pediatrics"},{"key":"10.1016\/j.jaip.2021.11.016_bib139","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1097\/01.psy.0000195797.78162.f4","article-title":"Major depression and allergy: does neuroticism explain the relationship?","volume":"68","author":"Goodwin","year":"2006","journal-title":"Psychosom Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib140","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1016\/j.jaip.2018.02.002","article-title":"Anxiety, depression, and asthma control: changes after standardized treatment","volume":"6","author":"Sastre","year":"2018","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2021.11.016_bib141","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/j.ijnurstu.2009.01.013","article-title":"Effect of relaxation-breathing training on anxiety and asthma signs\/symptoms of children with moderate-to-severe asthma: a randomized controlled trial","volume":"46","author":"Chiang","year":"2009","journal-title":"Int J Nurs Stud"},{"key":"10.1016\/j.jaip.2021.11.016_bib142","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1080\/02770903.2017.1350967","article-title":"Effectiveness of cognitive behavioural therapy in reducing anxiety in adults and children with asthma: a systematic review","volume":"55","author":"Pateraki","year":"2018","journal-title":"J\u00a0Asthma"},{"key":"10.1016\/j.jaip.2021.11.016_bib143","doi-asserted-by":"crossref","first-page":"30","DOI":"10.7748\/ncyp.24.9.30.s28","article-title":"Cognitive behaviour therapy for anxiety in children with asthma","volume":"24","author":"Marriage","year":"2012","journal-title":"Nurs Child Young People"},{"key":"10.1016\/j.jaip.2021.11.016_bib144","first-page":"CD011818","article-title":"Cognitive behavioural therapy (CBT) for adults and adolescents with asthma","volume":"9","author":"Kew","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jaip.2021.11.016_bib145","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1016\/j.jaip.2018.01.010","article-title":"A\u00a0randomized, double-blind, placebo-controlled trial of escitalopram in patients with asthma and major depressive disorder","volume":"6","author":"Brown","year":"2018","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2021.11.016_bib146","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1542\/peds.2008-1195","article-title":"Implications of a new definition of vitamin D deficiency in a multiracial us adolescent population: the National Health and Nutrition Examination Survey III","volume":"123","author":"Saintonge","year":"2009","journal-title":"Pediatrics"},{"key":"10.1016\/j.jaip.2021.11.016_bib147","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1093\/ajcn\/nqz037","article-title":"Vitamin D status in the United States, 2011-2014","volume":"110","author":"Herrick","year":"2019","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.jaip.2021.11.016_bib148","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1183\/09031936.00044710","article-title":"Serum vitamin D levels and exercise-induced bronchoconstriction in children with asthma","volume":"37","author":"Chinellato","year":"2011","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaip.2021.11.016_bib149","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1111\/all.12583","article-title":"The role of circulating 25 hydroxyvitamin D in asthma: a systematic review","volume":"70","author":"Cassim","year":"2015","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2021.11.016_bib150","doi-asserted-by":"crossref","first-page":"126","DOI":"10.2500\/aap.2020.41.190025","article-title":"Association of serum 25-OH vitamin D\u2083 with serum IgE and the Pediatric Asthma Severity Score in patients with pediatric asthma","volume":"41","author":"Mohammadzadeh","year":"2020","journal-title":"Allergy Asthma Proc"},{"key":"10.1016\/j.jaip.2021.11.016_bib151","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1164\/rccm.200911-1710OC","article-title":"Vitamin D levels, lung function, and steroid response in adult asthma","volume":"181","author":"Sutherland","year":"2010","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib152","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.jaci.2010.03.043","article-title":"Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study","volume":"126","author":"Brehm","year":"2010","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib153","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1164\/rccm.201203-0431OC","article-title":"Vitamin D insufficiency and severe asthma exacerbations in Puerto Rican children","volume":"186","author":"Brehm","year":"2012","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib154","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1089\/ped.2017.0803","article-title":"Diet, lung function, and asthma exacerbations in Puerto Rican children","volume":"30","author":"Han","year":"2017","journal-title":"Pediatr Allergy Immunol Pulmonol"},{"key":"10.1016\/j.jaip.2021.11.016_bib155","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1016\/j.jaci.2010.03.008","article-title":"Decreased serum vitamin D levels in children with asthma are associated with increased corticosteroid use","volume":"125","author":"Searing","year":"2010","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib156","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/S2213-2600(17)30306-5","article-title":"Vitamin D supplementation to prevent asthma exacerbations: a systematic review and meta-analysis of individual participant data","volume":"5","author":"Jolliffe","year":"2017","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib157","first-page":"CD011511","article-title":"Vitamin D for the management of asthma","volume":"9","author":"Martineau","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jaip.2021.11.016_bib158","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1001\/jama.2020.12384","article-title":"Effect of vitamin D3 supplementation on severe asthma exacerbations in children with asthma and low vitamin D levels: the VDKA randomized clinical trial","volume":"324","author":"Forno","year":"2020","journal-title":"JAMA"},{"key":"10.1016\/j.jaip.2021.11.016_bib159","doi-asserted-by":"crossref","first-page":"2083","DOI":"10.1001\/jama.2014.5052","article-title":"Effect of vitamin D3 on asthma treatment failures in adults with symptomatic asthma and lower vitamin D levels: the VIDA randomized clinical trial","volume":"311","author":"Castro","year":"2014","journal-title":"JAMA"},{"key":"10.1016\/j.jaip.2021.11.016_bib160","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1007\/s12098-018-2646-8","article-title":"Asthma and fungus: role in allergic bronchopulmonary aspergillosis (ABPA) and other conditions","volume":"85","author":"Singh","year":"2018","journal-title":"Indian J Pediatr"},{"key":"10.1016\/j.jaip.2021.11.016_bib161","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1007\/s11882-011-0217-4","article-title":"Severe asthma with fungal sensitization","volume":"11","author":"Agarwal","year":"2011","journal-title":"Curr Allergy Asthma Rep"},{"key":"10.1016\/j.jaip.2021.11.016_bib162","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1080\/17476348.2016.1249853","article-title":"Developments in the diagnosis and treatment of allergic bronchopulmonary aspergillosis","volume":"10","author":"Agarwal","year":"2016","journal-title":"Expert Rev Respir Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib163","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1111\/cea.12141","article-title":"Allergic bronchopulmonary aspergillosis: review of literature and proposal of new diagnostic and classification criteria","volume":"43","author":"Agarwal","year":"2013","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaip.2021.11.016_bib164","doi-asserted-by":"crossref","first-page":"148","DOI":"10.5415\/apallergy.2017.7.3.148","article-title":"A\u00a0review of 42 asthmatic children with allergic bronchopulmonary aspergillosis","volume":"7","author":"Shah","year":"2017","journal-title":"Asia Pac Allergy"},{"key":"10.1016\/j.jaip.2021.11.016_bib165","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1183\/09059180.00007413","article-title":"Allergic aspergillosis of the respiratory tract","volume":"23","author":"Shah","year":"2014","journal-title":"Eur Respir Rev"},{"key":"10.1016\/j.jaip.2021.11.016_bib166","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1002\/ppul.22779","article-title":"Fungal sensitization in childhood persistent asthma is associated with disease severity","volume":"49","author":"Vicencio","year":"2014","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.jaip.2021.11.016_bib167","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/j.jaip.2014.08.007","article-title":"Allergic bronchopulmonary aspergillosis","volume":"2","author":"Greenberger","year":"2014","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2021.11.016_bib168","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1056\/NEJM200003163421102","article-title":"A\u00a0randomized trial of itraconazole in allergic bronchopulmonary aspergillosis","volume":"342","author":"Stevens","year":"2000","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib169","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.rmed.2016.11.019","article-title":"Beneficial effects of omalizumab therapy in allergic bronchopulmonary aspergillosis: a synthesis review of published literature","volume":"122","author":"Li","year":"2017","journal-title":"Respir Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib170","doi-asserted-by":"crossref","first-page":"2315","DOI":"10.1016\/j.jaip.2021.02.048","article-title":"Real-world effectiveness of anti-IL-5\/5R therapy in severe atopic eosinophilic asthma with fungal sensitization","volume":"9","author":"Dhariwal","year":"2021","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2021.11.016_bib171","doi-asserted-by":"crossref","first-page":"2412","DOI":"10.1016\/j.jaip.2020.03.023","article-title":"Mepolizumab for allergic bronchopulmonary aspergillosis: report of 20 cases from the Belgian Severe Asthma Registry and review of the literature","volume":"8","author":"Schleich","year":"2020","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2021.11.016_bib172","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1186\/s12890-018-0617-5","article-title":"A\u00a0case of allergic bronchopulmonary aspergillosis successfully treated with mepolizumab","volume":"18","author":"Terashima","year":"2018","journal-title":"BMC Pulm Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib173","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1016\/j.jaip.2019.11.031","article-title":"Dupilumab treatment for allergic bronchopulmonary aspergillosis: a case series","volume":"8","author":"Ramonell","year":"2020","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2021.11.016_bib174","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1164\/rccm.200805-737OC","article-title":"Randomized controlled trial of oral antifungal treatment for severe asthma with fungal sensitization: the Fungal Asthma Sensitization Trial (FAST) study","volume":"179","author":"Denning","year":"2009","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib175","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.jaci.2013.09.050","article-title":"Effectiveness of voriconazole in the treatment of Aspergillus fumigatus-associated asthma (EVITA3 study)","volume":"134","author":"Agbetile","year":"2014","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib176","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1183\/09031936.00202013","article-title":"International ERS\/ATS guidelines on definition, evaluation and treatment of severe asthma","volume":"43","author":"Chung","year":"2014","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaip.2021.11.016_bib177","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1002\/ppul.21066","article-title":"Effect of active smoking on asthma symptoms, pulmonary function, and BHR in adolescents","volume":"44","author":"Yoo","year":"2009","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.jaip.2021.11.016_bib178","doi-asserted-by":"crossref","first-page":"8799","DOI":"10.3390\/ijerph17238799","article-title":"Mental health and the association between asthma and E-cigarette use among young adults in the United States: a mediation analysis","volume":"17","author":"Alanazi","year":"2020","journal-title":"Int J Environ Res Public Health"},{"key":"10.1016\/j.jaip.2021.11.016_bib179","doi-asserted-by":"crossref","first-page":"250","DOI":"10.3109\/02770903.2013.766751","article-title":"Effects of asthma on nicotine dependence development and smoking cessation attempts in adolescence","volume":"50","author":"Van De Ven","year":"2013","journal-title":"J\u00a0Asthma"},{"key":"10.1016\/j.jaip.2021.11.016_bib180","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/0091-6749(86)90348-9","article-title":"The effect of cigarette smoke from the mother on bronchial responsiveness and severity of symptoms in children with asthma","volume":"77","author":"Murray","year":"1986","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib181","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1542\/peds.85.4.505","article-title":"Maternal smoking and childhood asthma","volume":"85","author":"Weitzman","year":"1990","journal-title":"Pediatrics"},{"key":"10.1016\/j.jaip.2021.11.016_bib182","first-page":"567","article-title":"The impact of passive smoking on emergency room visits of urban children with asthma","volume":"135","author":"Evans","year":"1987","journal-title":"Am Rev Respir Dis"},{"key":"10.1016\/j.jaip.2021.11.016_bib183","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1164\/ajrccm\/138.3.518","article-title":"Parental smoking enhances bronchial responsiveness in nine-year-old children","volume":"138","author":"Martinez","year":"1988","journal-title":"Am Rev Respir Dis"},{"key":"10.1016\/j.jaip.2021.11.016_bib184","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1016\/S2213-2600(18)30099-7","article-title":"Lung function trajectories from pre-school age to adulthood and their associations with early life factors: a retrospective analysis of three population-based birth cohort studies","volume":"6","author":"Belgrave","year":"2018","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib185","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.anai.2015.06.027","article-title":"Asthma-associated comorbidities in children with and without secondhand smoke exposure","volume":"115","author":"Pyle","year":"2015","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib186","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/0091-6749(93)90302-V","article-title":"The decrease in severity of asthma in children of parents who smoke since the parents have been exposing them to less cigarette smoke","volume":"91","author":"Murray","year":"1993","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib187","unstructured":"Global Initiative for Asthma (GINA). Global Strategy for Asthma Management and Prevention; 2021. Accessed October 28, 2021. http:\/\/www.ginasthma.org\/"},{"key":"10.1016\/j.jaip.2021.11.016_bib188","doi-asserted-by":"crossref","first-page":"313","DOI":"10.3122\/jabfm.2011.03.100180","article-title":"Smoking and asthma","volume":"24","author":"Stapleton","year":"2011","journal-title":"J\u00a0Am Board Fam Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib189","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1096\/fsb2fj000432fje","article-title":"Cigarette smoking reduces histone deacetylase 2 expression, enhances cytokine expression, and inhibits glucocorticoid actions in alveolar macrophages","volume":"15","author":"Ito","year":"2001","journal-title":"FASEB J"},{"key":"10.1016\/j.jaip.2021.11.016_bib190","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1164\/rccm.200511-1746OC","article-title":"Smoking affects response to inhaled corticosteroids or leukotriene receptor antagonists in asthma","volume":"175","author":"Lazarus","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib191","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/j.jaci.2012.12.673","article-title":"Effect of montelukast for treatment of asthma in cigarette smokers","volume":"131","author":"Price","year":"2013","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib192","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0136065","article-title":"Asthma and COPD overlap syndrome (ACOS): a systematic review and meta analysis","volume":"10","author":"Alshabanat","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.jaip.2021.11.016_bib193","unstructured":"Global Initiative for Chronic Obstructive Lung Disease (GOLD). 2021 Global Strategy for Prevention, Diagnosis and Management of COPD; 2021. Accessed October 28, 2021. https:\/\/goldcopd.org\/"},{"key":"10.1016\/j.jaip.2021.11.016_bib194","doi-asserted-by":"crossref","first-page":"106906","DOI":"10.1016\/j.intimp.2020.106906","article-title":"Current insights on clinical efficacy of roflumilast for treatment of COPD, asthma and ACOS","volume":"88","author":"Bodkhe","year":"2020","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.jaip.2021.11.016_bib195","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0091-6749(86)90328-3","article-title":"Morbidity in asthma in relation to the menstrual cycle","volume":"77","author":"Eliasson","year":"1986","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib196","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1136\/thx.39.11.833","article-title":"Premenstrual exacerbation of asthma","volume":"39","author":"Gibbs","year":"1984","journal-title":"Thorax"},{"key":"10.1016\/j.jaip.2021.11.016_bib197","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1081\/JAS-120004921","article-title":"Airway inflammation in premenstrual asthma","volume":"39","author":"Oguzulgen","year":"2002","journal-title":"J\u00a0Asthma"},{"key":"10.1016\/j.jaip.2021.11.016_bib198","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1378\/chest.12-0973","article-title":"Characteristics of perimenstrual asthma and its relation to asthma severity and control: data from the Severe Asthma Research Program","volume":"143","author":"Rao","year":"2013","journal-title":"Chest"},{"key":"10.1016\/j.jaip.2021.11.016_bib199","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1136\/thx.2004.033928","article-title":"Relation between phase of the menstrual cycle and asthma presentations in the emergency department","volume":"60","author":"Brenner","year":"2005","journal-title":"Thorax"},{"key":"10.1016\/j.jaip.2021.11.016_bib200","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1164\/ajrccm.162.2.9910105","article-title":"Relation between phase of menstrual cycle and emergency department visits for acute asthma","volume":"162","author":"Zimmerman","year":"2000","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib201","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1016\/j.anai.2018.01.016","article-title":"Hormones, sex, and asthma","volume":"120","author":"Yung","year":"2018","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib202","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.jaci.2008.10.041","article-title":"Oral contraception, body mass index, and asthma: a cross-sectional Nordic-Baltic population survey","volume":"123","author":"Macsali","year":"2009","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib203","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1177\/0141076815588320","article-title":"Hormonal contraceptives and asthma in women of reproductive age: analysis of data from serial national Scottish Health Surveys","volume":"108","author":"Nwaru","year":"2015","journal-title":"J\u00a0R Soc Med"},{"key":"10.1016\/j.jaip.2021.11.016_bib204","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/0091-6749(88)90187-X","article-title":"The course of asthma during pregnancy, post partum, and with successive pregnancies: a prospective analysis","volume":"81","author":"Schatz","year":"1988","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib205","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1067\/mai.2003.1516","article-title":"Asthma morbidity during pregnancy can be predicted by severity classification","volume":"112","author":"Schatz","year":"2003","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2021.11.016_bib206","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1183\/09031936.05.00135604","article-title":"Asthma self-management skills and the use of asthma education during pregnancy","volume":"26","author":"Murphy","year":"2005","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaip.2021.11.016_bib207","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1097\/AOG.0b013e3181d06945","article-title":"Effect of pregnancy on maternal asthma symptoms and medication use","volume":"115","author":"Belanger","year":"2010","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.jaip.2021.11.016_bib208","doi-asserted-by":"crossref","first-page":"2157","DOI":"10.1016\/j.jaip.2018.04.020","article-title":"Overweight\/obesity enhances associations between secondhand smoke exposure and asthma morbidity in children","volume":"6","author":"Wu","year":"2018","journal-title":"J\u00a0Allergy Clin Immunol Pract"}],"container-title":["The Journal of Allergy and Clinical Immunology: In Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213219821012940?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213219821012940?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T05:32:45Z","timestamp":1761975165000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213219821012940"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":208,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["S2213219821012940"],"URL":"https:\/\/doi.org\/10.1016\/j.jaip.2021.11.016","relation":{},"ISSN":["2213-2198"],"issn-type":[{"value":"2213-2198","type":"print"}],"subject":[],"published":{"date-parts":[[2022,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Role of Comorbidities in Difficult-to-Control Asthma in Adults and Children","name":"articletitle","label":"Article Title"},{"value":"The Journal of Allergy and Clinical Immunology: In Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaip.2021.11.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 American Academy of Allergy, Asthma & Immunology","name":"copyright","label":"Copyright"}]}}