{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:28:40Z","timestamp":1786991320077,"version":"build-2736575974"},"reference-count":8,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T00:00:00Z","timestamp":1686096000000},"content-version":"am","delay-in-days":371,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["AHRQ \/ PCORI 1K12HS026395-01"],"award-info":[{"award-number":["AHRQ \/ PCORI 1K12HS026395-01"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000133","name":"AHRQ","doi-asserted-by":"publisher","award":["1K12HS026395-01"],"award-info":[{"award-number":["1K12HS026395-01"]}],"id":[{"id":"10.13039\/100000133","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100002894","name":"American Academy of Allergy Asthma and Immunology Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002894","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004339","name":"Sanofi","doi-asserted-by":"publisher","award":["UL1RR024975"],"award-info":[{"award-number":["UL1RR024975"]}],"id":[{"id":"10.13039\/100004339","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004339","name":"Sanofi","doi-asserted-by":"publisher","award":["U01HL123033"],"award-info":[{"award-number":["U01HL123033"]}],"id":[{"id":"10.13039\/100004339","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01HG010863"],"award-info":[{"award-number":["R01HG010863"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["UAI109565"],"award-info":[{"award-number":["UAI109565"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R13AR078623"],"award-info":[{"award-number":["R13AR078623"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01AI152183"],"award-info":[{"award-number":["R01AI152183"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U01AI154659"],"award-info":[{"award-number":["U01AI154659"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006093","name":"Patient-Centered Outcomes Research Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006093","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaci-inpractice.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Allergy and Clinical Immunology: In Practice"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1016\/j.jaip.2022.01.041","type":"journal-article","created":{"date-parts":[[2022,2,5]],"date-time":"2022-02-05T02:56:47Z","timestamp":1644029807000},"page":"1660-1663.e2","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":45,"title":["Low-risk penicillin allergy delabeling through a direct oral challenge in immunocompromised and\/or multiple drug allergy labeled patients in a critical care setting"],"prefix":"10.1016","volume":"10","author":[{"given":"Grace","family":"Koo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna L.","family":"Stollings","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Lindsell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Lynn","family":"Dear","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil","family":"Kripalani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George E.","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison B.","family":"McCoy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd W.","family":"Rice","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth J.","family":"Phillips","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Cosby A.","family":"Stone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaip.2022.01.041_bib1","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1111\/bcp.13830","article-title":"Antibiotic allergy labels in hospitalized and critically ill adults: a review of current impacts of inaccurate labelling","volume":"85","author":"Moran","year":"2019","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.jaip.2022.01.041_bib2","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1164\/rccm.202001-0089LE","article-title":"Risk-stratified management to remove low-risk penicillin allergy labels in the ICU","volume":"201","author":"Stone","year":"2020","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaip.2022.01.041_bib3","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1007\/s00134-016-4224-8","article-title":"Focus on immunocompromised patients","volume":"42","author":"Azoulay","year":"2016","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.jaip.2022.01.041_bib4","doi-asserted-by":"crossref","first-page":"2870","DOI":"10.1016\/j.jaip.2020.08.033","article-title":"Tackling the patient with multiple drug \"allergies\": multiple drug intolerance syndrome","volume":"8","author":"Guyer","year":"2020","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.01.041_bib5","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1016\/j.jaip.2020.09.010","article-title":"Safety, efficacy, and effectiveness of delabeling in patients with multiple drug allergy labels","volume":"9","author":"Vethody","year":"2021","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.01.041_bib6","doi-asserted-by":"crossref","first-page":"2151","DOI":"10.1016\/j.jaip.2019.05.051","article-title":"Beta-lactam and sulfonamide allergy testing should be a standard of care in immunocompromised hosts","volume":"7","author":"Trubiano","year":"2019","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.01.041_bib7","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.jaip.2020.07.056","article-title":"Testing strategies and predictors for evaluating immediate and delayed reactions to cephalosporins","volume":"9","author":"Stone","year":"2021","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.01.041_bib8","first-page":"132","article-title":"Sulfonamide allergies","volume":"7","author":"Giles","year":"2019","journal-title":"Pharmacy (Basel)"}],"container-title":["The Journal of Allergy and Clinical Immunology: In Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213219822001210?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213219822001210?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T18:12:29Z","timestamp":1778523149000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213219822001210"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":8,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["S2213219822001210"],"URL":"https:\/\/doi.org\/10.1016\/j.jaip.2022.01.041","relation":{},"ISSN":["2213-2198"],"issn-type":[{"value":"2213-2198","type":"print"}],"subject":[],"published":{"date-parts":[[2022,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Low-risk penicillin allergy delabeling through a direct oral challenge in immunocompromised and\/or multiple drug allergy labeled patients in a critical care setting","name":"articletitle","label":"Article Title"},{"value":"The Journal of Allergy and Clinical Immunology: In Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaip.2022.01.041","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 American Academy of Allergy, Asthma & Immunology","name":"copyright","label":"Copyright"}]}}