{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T12:06:11Z","timestamp":1793016371776,"version":"4.5.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,4,21]],"date-time":"2022-04-21T00:00:00Z","timestamp":1650499200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100006512","name":"School of Medicine, Duke University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006512","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007928","name":"Perelman School of Medicine, University of Pennsylvania","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007928","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004339","name":"Sanofi","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004339","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009857","name":"Regeneron Pharmaceuticals","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009857","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002581","name":"School of Medicine, CHA University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002581","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100002491","name":"Bristol-Myers Squibb","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002491","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006458","name":"Children&apos;s Hospital of Philadelphia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006458","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaci-inpractice.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Allergy and Clinical Immunology: In Practice"],"published-print":{"date-parts":[[2022,7]]},"DOI":"10.1016\/j.jaip.2022.02.049","type":"journal-article","created":{"date-parts":[[2022,4,8]],"date-time":"2022-04-08T10:50:14Z","timestamp":1649415014000},"page":"1856-1863.e3","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Novel Questionnaires for Assessing Signs and Symptoms of Eosinophilic Esophagitis in Children"],"prefix":"10.1016","volume":"10","author":[{"given":"Siddhesh","family":"Kamat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Yaworsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Guillemin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meaghan","family":"Krohe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leighann","family":"Litcher-Kelly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan","family":"McLafferty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger E.","family":"Lamoureux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caitlyn","family":"Lowe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirna","family":"Chehade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan M.","family":"Spergel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Weinfurt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diane M.","family":"Turner-Bowker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaip.2022.02.049_bib1","doi-asserted-by":"crossref","DOI":"10.1053\/j.gastro.2017.06.067","article-title":"Epidemiology and natural history of eosinophilic esophagitis","volume":"154","author":"Dellon","year":"2018","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jaip.2022.02.049_bib2","doi-asserted-by":"crossref","first-page":"132","DOI":"10.12968\/hmed.2019.80.3.132","article-title":"Overview of eosinophilic oesophagitis","volume":"80","author":"Attwood","year":"2019","journal-title":"Br J Hosp Med (Lond)"},{"key":"10.1016\/j.jaip.2022.02.049_bib3","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1097\/MPG.0b013e318291fee2","article-title":"Incidence and prevalence of eosinophilic esophagitis in children","volume":"57","author":"Soon","year":"2013","journal-title":"J\u00a0Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.jaip.2022.02.049_bib4","doi-asserted-by":"crossref","first-page":"S8","DOI":"10.1186\/1710-1492-7-S1-S8","article-title":"Eosinophilic esophagitis","volume":"7","author":"Carr","year":"2011","journal-title":"Allergy Asthma Clin Immunol"},{"key":"10.1016\/j.jaip.2022.02.049_bib5","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1586\/eci.12.68","article-title":"Adult versus pediatric eosinophilic esophagitis: important differences and similarities for the clinician to understand","volume":"8","author":"Lucendo","year":"2012","journal-title":"Expert Rev Clin Immunol"},{"key":"10.1016\/j.jaip.2022.02.049_bib7","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/j.bpg.2015.09.005","article-title":"Clinical features of eosinophilic esophagitis in children and adults","volume":"29","author":"Miehlke","year":"2015","journal-title":"Best Pract Res Clin Gastroenterol"},{"key":"10.1016\/j.jaip.2022.02.049_bib8","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1097\/MCG.0b013e3182166a5a","article-title":"Qualitative assessment of patient-reported outcomes in adults with eosinophilic esophagitis","volume":"45","author":"Taft","year":"2011","journal-title":"J\u00a0Clin Gastroenterol"},{"key":"10.1016\/j.jaip.2022.02.049_bib9","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1053\/j.gastro.2014.08.028","article-title":"Development and validation of a symptom-based activity index for adults with eosinophilic esophagitis","volume":"147","author":"Schoepfer","year":"2014","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jaip.2022.02.049_bib10","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.gtc.2014.02.012","article-title":"Eosinophilic esophagitis: clinical presentation in children","volume":"43","author":"Liacouras","year":"2014","journal-title":"Gastroenterol Clin N Am"},{"key":"10.1016\/j.jaip.2022.02.049_bib11","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1016\/j.cgh.2017.03.016","article-title":"White paper AGA: drug development for eosinophilic esophagitis","volume":"15","author":"Hirano","year":"2017","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.jaip.2022.02.049_bib12","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1097\/MPG.0b013e3181788282","article-title":"14 years of eosinophilic esophagitis: clinical features and prognosis","volume":"48","author":"Spergel","year":"2009","journal-title":"J\u00a0Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.jaip.2022.02.049_bib13","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s12016-015-8501-z","article-title":"Eosinophilic esophagitis: a comprehensive review","volume":"50","author":"Cianferoni","year":"2016","journal-title":"Clin Rev Allergy Immunol"},{"key":"10.1016\/j.jaip.2022.02.049_bib14","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1097\/MPG.0b013e31817f0197","article-title":"Dissociation between symptoms and histological severity in pediatric eosinophilic esophagitis","volume":"48","author":"Pentiuk","year":"2009","journal-title":"J\u00a0Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.jaip.2022.02.049_bib15","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1159\/000357012","article-title":"Histopathology of eosinophilic esophagitis","volume":"32","author":"Collins","year":"2014","journal-title":"Dig Dis"},{"key":"10.1016\/j.jaip.2022.02.049_bib16","series-title":"Eosinophilic esophagitis: developing drugs for treatment guidance for industry","year":"2020"},{"key":"10.1016\/j.jaip.2022.02.049_bib17","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1016\/j.jaci.2015.03.004","article-title":"Pediatric eosinophilic esophagitis symptom scores (PEESS v2.0) identify histologic and molecular correlates of the key clinical features of disease","volume":"135","author":"Martin","year":"2015","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.02.049_bib18","doi-asserted-by":"crossref","first-page":"3369","DOI":"10.1185\/03007990802536900","article-title":"Patient and caregiver perspective on pediatric eosinophilic esophagitis and newly developed symptom questionnaires","volume":"24","author":"Flood","year":"2008","journal-title":"Curr Med Res Opin"},{"key":"10.1016\/j.jaip.2022.02.049_bib19","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/j.jval.2017.11.014","article-title":"Informing a priori sample size estimation in qualitative concept elicitation interview studies for clinical outcome assessment instrument development","volume":"21","author":"Turner-Bowker","year":"2018","journal-title":"Value Health"},{"key":"10.1016\/j.jaip.2022.02.049_bib20","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1016\/j.jval.2011.06.013","article-title":"Content validity-establishing and reporting the evidence in newly developed patient-reported outcomes (PRO) instruments for medical product evaluation: ISPOR PRO Good Research Practices Task Force Report: part 2\u2014assessing respondent understanding","volume":"14","author":"Patrick","year":"2011","journal-title":"Value Health"},{"key":"10.1016\/j.jaip.2022.02.049_bib21","year":"2009"},{"key":"10.1016\/j.jaip.2022.02.049_bib22","series-title":"Patient-Focused Drug Development: Collecting Comprehensive and Representative Input\u2014Guidance for Industry, Food and Drug Administration Staff, and Other Stakeholders","year":"2020"},{"key":"10.1016\/j.jaip.2022.02.049_bib23","series-title":"Educational Research: Quantitative, Qualitative, and Mixed Approaches","first-page":"189","article-title":"How to construct a questionnaire","author":"Johnson","year":"2017"},{"key":"10.1016\/j.jaip.2022.02.049_bib24","doi-asserted-by":"crossref","unstructured":"Lamoureux R, Galipeau N, Yaworsky A, Stokes J, Shields A. How many subjects are enough for symptom-focused concept elicitation studies? A retrospective analysis of saturation across twenty-six studies. Abstract presented at the 20th Annual International Meeting of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR); May 16-20, 2015; Philadelphia, PA.","DOI":"10.1016\/j.jval.2015.03.198"},{"key":"10.1016\/j.jaip.2022.02.049_bib25","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1001\/jama.1995.03520250075037","article-title":"Linking clinical variables with health-related quality of life. A conceptual model of patient outcomes","volume":"273","author":"Wilson","year":"1995","journal-title":"JAMA"},{"key":"10.1016\/j.jaip.2022.02.049_bib26","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1038\/ajg.2011.342","article-title":"Influence of race and gender on the presentation of eosinophilic esophagitis","volume":"107","author":"Sperry","year":"2012","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.jaip.2022.02.049_bib27","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.iac.2008.09.011","article-title":"Psychological impact of eosinophilic esophagitis on children and families","volume":"29","author":"Klinnert","year":"2009","journal-title":"Immunol Allergy Clin N Am"},{"key":"10.1016\/j.jaip.2022.02.049_bib28","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.gtc.2014.02.002","article-title":"Epidemiology of eosinophilic esophagitis","volume":"43","author":"Dellon","year":"2014","journal-title":"Gastroenterol Clin N Am"},{"key":"10.1016\/j.jaip.2022.02.049_bib29","doi-asserted-by":"crossref","first-page":"75","DOI":"10.4082\/kjfm.18.0162","article-title":"Eosinophilic esophagitis in adults: a concise overview of an evolving disease","volume":"41","author":"Mari","year":"2020","journal-title":"Korean J Fam Med"},{"key":"10.1016\/j.jaip.2022.02.049_bib30","doi-asserted-by":"crossref","first-page":"doy015","DOI":"10.1093\/dote\/doy015","article-title":"Natural history of eosinophilic esophagitis: a systematic review of epidemiology and disease course","volume":"31","author":"Shaheen","year":"2018","journal-title":"Dis Esophagus"}],"container-title":["The Journal of Allergy and Clinical Immunology: In Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213219822003312?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213219822003312?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T05:34:43Z","timestamp":1761975283000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213219822003312"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":29,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["S2213219822003312"],"URL":"https:\/\/doi.org\/10.1016\/j.jaip.2022.02.049","relation":{},"ISSN":["2213-2198"],"issn-type":[{"value":"2213-2198","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Novel Questionnaires for Assessing Signs and Symptoms of Eosinophilic Esophagitis in Children","name":"articletitle","label":"Article Title"},{"value":"The Journal of Allergy and Clinical Immunology: In Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaip.2022.02.049","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology.","name":"copyright","label":"Copyright"}]}}