{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T20:31:10Z","timestamp":1777494670554,"version":"3.51.4"},"reference-count":35,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,1,5]],"date-time":"2024-01-05T00:00:00Z","timestamp":1704412800000},"content-version":"am","delay-in-days":369,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaci-inpractice.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Allergy and Clinical Immunology: In Practice"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1016\/j.jaip.2022.10.011","type":"journal-article","created":{"date-parts":[[2022,10,21]],"date-time":"2022-10-21T23:53:06Z","timestamp":1666396386000},"page":"238-247","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Sensitivity of FEV1 and Clinical Parameters in Children With a Suspected Asthma Diagnosis"],"prefix":"10.1016","volume":"11","author":[{"given":"Anouchka","family":"Fillard","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amelia","family":"Licari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Molinari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GianLuigi","family":"Marseglia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pascal","family":"Demoly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davide","family":"Caimmi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaip.2022.10.011_bib1","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1186\/1824-7288-38-60","article-title":"Nose and lungs: one way, one disease","volume":"38","author":"Caimmi","year":"2012","journal-title":"Ital J Pediatr"},{"key":"10.1016\/j.jaip.2022.10.011_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/ppul.21321","article-title":"Global Initiative for Asthma. Global strategy for the diagnosis and management of asthma in children 5 years and younger","volume":"46","author":"Pedersen","year":"2011","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.jaip.2022.10.011_bib3","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/S0140-6736(17)33311-1","article-title":"Asthma","volume":"391","author":"Papi","year":"2018","journal-title":"Lancet"},{"key":"10.1016\/j.jaip.2022.10.011_bib4","author":"Global Initiative for Asthma"},{"key":"10.1016\/j.jaip.2022.10.011_bib5","series-title":"Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma","author":"National Heart","year":"2007"},{"key":"10.1016\/j.jaip.2022.10.011_bib6","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.jaci.2006.04.004","article-title":"Prevention of asthma during the first 5 years of life: a randomized controlled trial","volume":"118","author":"Marks","year":"2006","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.10.011_bib7","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1056\/NEJM199501193320301","article-title":"Asthma and wheezing in the first six years of life. The Group Health Medical Associates","volume":"332","author":"Martinez","year":"1995","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jaip.2022.10.011_bib8","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1111\/j.1365-2222.2007.02784.x","article-title":"Wheeze and asthma prevalence and related health-service use in white and south Asian pre-schoolchildren in the United Kingdom","volume":"37","author":"Kuehni","year":"2007","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaip.2022.10.011_bib9","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1111\/j.1467-8624.2004.00724.x","article-title":"Socioeconomic status and health in adolescents: the role of stress interpretations","volume":"75","author":"Chen","year":"2004","journal-title":"Child Dev"},{"key":"10.1016\/j.jaip.2022.10.011_bib10","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.jaip.2015.09.006","article-title":"Mouse sensitivity is an independent risk factor for rhinitis in children with asthma","volume":"4","author":"Sedaghat","year":"2016","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.10.011_bib11","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1016\/S0140-6736(08)61451-8","article-title":"Early identification of atopy in the prediction of persistent asthma in children","volume":"372","author":"Sly","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.jaip.2022.10.011_bib12","doi-asserted-by":"crossref","first-page":"4","DOI":"10.3132\/pcrj.2007.00011","article-title":"Preschool asthma\u2013not so easy to diagnose","volume":"16","author":"Pedersen","year":"2007","journal-title":"Prim Care Respir J"},{"key":"10.1016\/j.jaip.2022.10.011_bib13","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1164\/rccm.200401-083OC","article-title":"on behalf of the NAC Manchester Asthma and Allergy Study Group. Early life environmental control: effect on symptoms, sensitization, and lung function at age 3 years","volume":"170","author":"Woodcock","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaip.2022.10.011_bib14","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1007\/s11882-007-0057-4","article-title":"Early exposure to pets: good or bad?","volume":"7","author":"Bufford","year":"2007","journal-title":"Curr Allergy Asthma Rep"},{"key":"10.1016\/j.jaip.2022.10.011_bib15","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1001\/jama.288.8.963","article-title":"Exposure to dogs and cats in the first year of life and risk of allergic sensitization at 6 to 7 years of age","volume":"288","author":"Ownby","year":"2002","journal-title":"JAMA"},{"key":"10.1016\/j.jaip.2022.10.011_bib16","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1056\/NEJMoa022363","article-title":"A\u00a0longitudinal, population-based, cohort study of childhood asthma followed to adulthood","volume":"349","author":"Sears","year":"2003","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jaip.2022.10.011_bib17","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1164\/ajrccm.160.1.9707103","article-title":"Risk factors from childhood to adulthood for bronchial responsiveness at age 32-42 yr","volume":"160","author":"Grol","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaip.2022.10.011_bib18","doi-asserted-by":"crossref","first-page":"e70","DOI":"10.1164\/rccm.201908-1590ST","article-title":"Standardization of Spirometry 2019 Update. An Official American Thoracic Society and European Respiratory Society Technical Statement","volume":"200","author":"Graham","year":"2019","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaip.2022.10.011_bib19","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1002\/ppul.1950190209","article-title":"Spirometric reference values for white European children and adolescents: Polgar revisited","volume":"19","author":"Quanjer","year":"1995","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.jaip.2022.10.011_bib20","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1183\/09031936.00080312","article-title":"the ERS Global Lung function Initiative. Multi-ethnic reference values for spirometry for the 3-95 year age range: the global lung function 2012 equations","volume":"40","author":"Quanjer","year":"2012","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaip.2022.10.011_bib21","doi-asserted-by":"crossref","first-page":"221","DOI":"10.4104\/pcrj.2013.00042","article-title":"Spirometry in children","volume":"22","author":"Jat","year":"2013","journal-title":"Prim Care Respir J"},{"key":"10.1016\/j.jaip.2022.10.011_bib22","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1002\/ppul.1089","article-title":"Spirometry in children aged 3 to 5 years: reliability of forced expiratory maneuvers","volume":"32","author":"Crenesse","year":"2001","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.jaip.2022.10.011_bib23","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.anai.2016.04.029","article-title":"The association of FEF25\u201375 and bronchodilator reversibility with asthma control and asthma morbidity in inner city children with asthma","volume":"117","author":"Kanchongkittiphon","year":"2016","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.jaip.2022.10.011_bib24","doi-asserted-by":"crossref","first-page":"586","DOI":"10.3109\/02770903.2012.690481","article-title":"The utility of forced expiratory flow between 25% and 75% of vital capacity in predicting childhood asthma morbidity and severity","volume":"49","author":"Rao","year":"2012","journal-title":"J\u00a0Asthma"},{"key":"10.1016\/j.jaip.2022.10.011_bib26","doi-asserted-by":"crossref","first-page":"413","DOI":"10.3109\/02770903.2015.1108436","article-title":"A\u00a0literature review of the evidence that a 12% improvement in FEV1 is an appropriate cut-off for children","volume":"53","author":"Hopp","year":"2016","journal-title":"J\u00a0Asthma"},{"key":"10.1016\/j.jaip.2022.10.011_bib27","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1164\/rccm.200308-1178OC","article-title":"Classifying asthma severity in children: mismatch between symptoms, medication use, and lung function","volume":"170","author":"Bacharier","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaip.2022.10.011_bib28","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1016\/j.jaci.2008.09.004","article-title":"Clinical predictors and outcomes of consistent bronchodilator response in the Childhood Asthma Management Program","volume":"122","author":"Sharma","year":"2008","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.10.011_bib29","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1111\/jdv.14891","article-title":"Consensus-based European guidelines for treatment of atopic eczema (atopic dermatitis) in adults and children: part I","volume":"32","author":"Wollenberg","year":"2018","journal-title":"J\u00a0Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.jaip.2022.10.011_bib30","article-title":"Assessment of airway bronchodilation by spirometry compared to airway obstruction in young children with asthma","volume":"2016","author":"Vilozni","year":"2016","journal-title":"Can Respir J"},{"key":"10.1016\/j.jaip.2022.10.011_bib31","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/S1695-4033(02)77885-5","article-title":"Cut-off point for a positive bronchodilation test","volume":"57","author":"Pardos Mart\u00ednez","year":"2002","journal-title":"Esp Pediatr"},{"key":"10.1016\/j.jaip.2022.10.011_bib32","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1007\/s12519-019-00293-9","article-title":"A\u00a0clinical study to determine the threshold of bronchodilator response for diagnosing asthma in Chinese children","volume":"15","author":"Kang","year":"2019","journal-title":"World J Pediatr"},{"key":"10.1016\/j.jaip.2022.10.011_bib33","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.jaci.2010.05.016","volume":"126","author":"Simon","year":"2010","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.10.011_bib34","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.jaci.2010.10.053","article-title":"Forced expiratory flow between 25% and 75% of vital capacity may be a marker of bronchial impairment in allergic rhinitis","volume":"127","author":"Ciprandi","year":"2011","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.10.011_bib35","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.00373-2018","article-title":"Should reversibility be assessed in all asthmatic children with normal spirometry?","volume":"52","author":"Dufetelle","year":"2018","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaip.2022.10.011_bib36","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/S2352-4642(17)30008-1","article-title":"Diagnosis of asthma in symptomatic children based on measures of lung function: an analysis of data from a population-based birth cohort study","volume":"1","author":"Murray","year":"2017","journal-title":"Lancet Child Adolesc Health"}],"container-title":["The Journal of Allergy and Clinical Immunology: In Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213219822010534?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213219822010534?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T05:36:01Z","timestamp":1761975361000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213219822010534"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["S2213219822010534"],"URL":"https:\/\/doi.org\/10.1016\/j.jaip.2022.10.011","relation":{},"ISSN":["2213-2198"],"issn-type":[{"value":"2213-2198","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sensitivity of FEV1 and Clinical Parameters in Children With a Suspected Asthma Diagnosis","name":"articletitle","label":"Article Title"},{"value":"The Journal of Allergy and Clinical Immunology: In Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaip.2022.10.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 American Academy of Allergy, Asthma & Immunology","name":"copyright","label":"Copyright"}]}}