{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T11:20:41Z","timestamp":1782127241622,"version":"3.54.5"},"reference-count":109,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaci-inpractice.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Allergy and Clinical Immunology: In Practice"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1016\/j.jaip.2022.10.030","type":"journal-article","created":{"date-parts":[[2023,1,5]],"date-time":"2023-01-05T04:56:35Z","timestamp":1672894595000},"page":"43-50","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["A Decade of Clinical Advances in Chronic Rhinosinusitis: 2012\u20132022"],"prefix":"10.1016","volume":"11","author":[{"given":"Robert","family":"Naclerio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaquim","family":"Mullol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Whitney W.","family":"Stevens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaip.2022.10.030_bib1","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.anai.2014.07.025","article-title":"Diagnosis and management of rhinosinusitis: a practice parameter update","volume":"113","author":"Peters","year":"2014","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.jaip.2022.10.030_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4193\/Rhin20.401","article-title":"European Position Paper on Rhinosinusitis and Nasal Polyps 2020","volume":"58","author":"Fokkens","year":"2020","journal-title":"Rhinology"},{"key":"10.1016\/j.jaip.2022.10.030_bib3","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1002\/alr.22741","article-title":"International Consensus Statement on Allergy and Rhinology: Rhinosinusitis 2021","volume":"11","author":"Orlandi","year":"2021","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2022.10.030_bib4","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1016\/j.jaip.2022.01.013","article-title":"A\u00a0comparison of international guidelines for rhinosinusitis","volume":"10","author":"Fokkens","year":"2022","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.10.030_bib5","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1111\/all.14106","article-title":"Radiologic sinus inflammation and symptoms of chronic rhinosinusitis in a population-based sample","volume":"75","author":"Hirsch","year":"2020","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2022.10.030_bib6","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1111\/j.1398-9995.2005.00688.x","article-title":"Prevalence of nasal polyposis in France: a cross-sectional, case-control study","volume":"60","author":"Klossek","year":"2005","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2022.10.030_bib7","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1111\/j.1398-9995.2011.02646.x","article-title":"Chronic rhinosinusitis in Europe\u2014an underestimated disease. A GA(2)LEN study","volume":"66","author":"Hastan","year":"2011","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2022.10.030_bib8","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1016\/j.jaci.2013.01.028","article-title":"Genetics of chronic rhinosinusitis: state of the field and directions forward","volume":"131","author":"Hsu","year":"2013","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.10.030_bib9","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1002\/alr.21252","article-title":"New insights into the pathogenesis of cystic fibrosis sinusitis","volume":"4","author":"Chang","year":"2014","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2022.10.030_bib10","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1016\/j.jcf.2022.03.002","article-title":"Elexacaftor-tezacaftor-ivacaftor improves sinonasal outcomes in cystic fibrosis","volume":"21","author":"Stapleton","year":"2022","journal-title":"J\u00a0Cyst Fibros"},{"key":"10.1016\/j.jaip.2022.10.030_bib11","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1002\/alr.22887","article-title":"The association of active and passive tobacco smoke exposure with chronic rhinosinusitis symptom severity: a cross-sectional study","volume":"12","author":"Wolf","year":"2022","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2022.10.030_bib12","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.1002\/lary.29974","article-title":"Air pollution exposure affects severity and cellular endotype of chronic rhinosinusitis with nasal polyps","volume":"132","author":"Yang","year":"2022","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jaip.2022.10.030_bib13","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1016\/j.jaip.2022.03.003","article-title":"Chronic rhinosinusitis and COVID-19","volume":"10","author":"Marin","year":"2022","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.10.030_bib14","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1016\/j.jaci.2022.02.022","article-title":"Unraveling the role of the microbiome in chronic rhinosinusitis","volume":"149","author":"Psaltis","year":"2022","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.10.030_bib15","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1016\/j.jaip.2020.09.063","article-title":"Chronic rhinosinusitis with nasal polyps and asthma","volume":"9","author":"Laidlaw","year":"2021","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.10.030_bib16","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1016\/j.jaip.2018.10.014","article-title":"Clinical characteristics of patients with chronic rhinosinusitis without nasal polyps in an academic setting","volume":"7","author":"Benjamin","year":"2019","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.10.030_bib17","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/j.jaip.2016.12.027","article-title":"Clinical characteristics of patients with chronic rhinosinusitis with nasal polyps, asthma, and aspirin-exacerbated respiratory disease","volume":"5","author":"Stevens","year":"2017","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.10.030_bib18","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1111\/all.12222","article-title":"Chronic rhinosinusitis in asthma is a negative predictor of quality of life: results from the Swedish GA(2)LEN survey","volume":"68","author":"Ek","year":"2013","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2022.10.030_bib19","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1164\/rccm.201602-0419OC","article-title":"Inflammatory and comorbid features of patients with severe asthma and frequent exacerbations","volume":"195","author":"Denlinger","year":"2017","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaip.2022.10.030_bib20","doi-asserted-by":"crossref","first-page":"205","DOI":"10.2500\/ajra.2011.25.3613","article-title":"Association between severity of asthma and degree of chronic rhinosinusitis","volume":"25","author":"Lin","year":"2011","journal-title":"Am J Rhinol Allergy"},{"key":"10.1016\/j.jaip.2022.10.030_bib21","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1002\/alr.22064","article-title":"Asthma onset pattern and patient outcomes in a chronic rhinosinusitis population","volume":"8","author":"Staniorski","year":"2018","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2022.10.030_bib22","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1002\/lary.24418","article-title":"Analysis of comorbidities and objective parameters in refractory chronic rhinosinusitis","volume":"123","author":"Batra","year":"2013","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jaip.2022.10.030_bib23","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1080\/02770903.2020.1729380","article-title":"Impact of sinus surgery on type 2 airway and systemic inflammation in asthma","volume":"58","author":"Hamada","year":"2021","journal-title":"J\u00a0Asthma"},{"key":"10.1016\/j.jaip.2022.10.030_bib24","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1002\/alr.22436","article-title":"Prevalence and characterization of chronic rhinosinusitis in patients with non-cystic fibrosis bronchiectasis at a tertiary care center in the United States","volume":"9","author":"Somani","year":"2019","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2022.10.030_bib25","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1016\/j.jaip.2019.02.026","article-title":"Prevalence and clinical implications of chronic rhinosinusitis in people with bronchiectasis: a systematic review","volume":"7","author":"Handley","year":"2019","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.10.030_bib26","doi-asserted-by":"crossref","first-page":"3188","DOI":"10.1016\/j.jaip.2021.04.054","article-title":"Prevalence of bronchiectasis in patients with chronic rhinosinusitis in a tertiary care center","volume":"9","author":"Peters","year":"2021","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.10.030_bib27","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/j.jaci.2022.03.006","article-title":"Strong and consistent associations of precedent chronic rhinosinusitis with risk of non-cystic fibrosis bronchiectasis","volume":"150","author":"Schwartz","year":"2022","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.10.030_bib28","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1002\/alr.22663","article-title":"Central compartment atopic disease: the missing link in the allergy and chronic rhinosinusitis with nasal polyps saga","volume":"10","author":"DelGaudio","year":"2020","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2022.10.030_bib29","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.anai.2017.03.009","article-title":"Risk of obstructive sleep apnea in African American patients with chronic rhinosinusitis","volume":"118","author":"Hui","year":"2017","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.jaip.2022.10.030_bib30","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1002\/alr.22259","article-title":"Gastroesophageal reflux disease increases the risk of chronic rhinosinusitis: a nested case-control study using a national sample cohort","volume":"9","author":"Kim","year":"2019","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2022.10.030_bib31","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1016\/j.jaci.2013.02.002","article-title":"Incidence and associated premorbid diagnoses of patients with chronic rhinosinusitis","volume":"131","author":"Tan","year":"2013","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.10.030_bib32","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1016\/j.jaip.2016.11.033","article-title":"The clinical significance of specific antibody deficiency (SAD) severity in chronic rhinosinusitis (CRS)","volume":"5","author":"Keswani","year":"2017","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.10.030_bib33","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.jaip.2014.09.022","article-title":"Clinical characteristics of adults with chronic rhinosinusitis and specific antibody deficiency","volume":"3","author":"Kashani","year":"2015","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.10.030_bib34","doi-asserted-by":"crossref","first-page":"2567","DOI":"10.2147\/JIR.S284768","article-title":"ANCA associated vasculitis subtypes: recent insights and future perspectives","volume":"15","author":"Austin","year":"2022","journal-title":"J\u00a0Inflamm Res"},{"key":"10.1016\/j.jaip.2022.10.030_bib35","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.jaci.2020.01.024","article-title":"The sense of smell in chronic rhinosinusitis","volume":"145","author":"Mullol","year":"2020","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.10.030_bib36","first-page":"1","article-title":"Chronic rhinosinusitis impairs sleep quality: results of the GA2LEN study","volume":"40","author":"Bengtsson","year":"2017","journal-title":"Sleep"},{"key":"10.1016\/j.jaip.2022.10.030_bib37","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1002\/alr.21581","article-title":"Cognitive function in chronic rhinosinusitis: a controlled clinical study","volume":"5","author":"Soler","year":"2015","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2022.10.030_bib38","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1007\/s00405-012-2230-1","article-title":"The impact of mental health on chronic rhinosinusitis symptom scores","volume":"270","author":"Nanayakkara","year":"2013","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"10.1016\/j.jaip.2022.10.030_bib39","doi-asserted-by":"crossref","first-page":"129","DOI":"10.4193\/Rhino15.072","article-title":"Stratification of SNOT-22 scores into mild, moderate or severe and relationship with other subjective instruments","volume":"54","author":"Toma","year":"2016","journal-title":"Rhinology"},{"key":"10.1016\/j.jaip.2022.10.030_bib40","doi-asserted-by":"crossref","first-page":"2341","DOI":"10.1016\/j.jaip.2020.04.048","article-title":"Development and preliminary validation of a new patient-reported outcome measure for chronic rhinosinusitis (CRS-PRO)","volume":"8","author":"Ghadersohi","year":"2020","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.10.030_bib41","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1002\/lary.24715","article-title":"The EQ-5D: a new tool for studying clinical outcomes in chronic rhinosinusitis","volume":"125","author":"Remenschneider","year":"2015","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jaip.2022.10.030_bib42","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1016\/j.jaip.2022.03.002","article-title":"Chronic rhinosinusitis with nasal polyps: quality of life in the biologics era","volume":"10","author":"Mullol","year":"2022","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.10.030_bib43","doi-asserted-by":"crossref","first-page":"311","DOI":"10.4193\/Rhino15.361","article-title":"A\u00a0cross sectional analysis of a case-control study about quality of life in CRS in the UK; a comparison between CRS subtypes","volume":"54","author":"Erskine","year":"2016","journal-title":"Rhinology"},{"key":"10.1016\/j.jaip.2022.10.030_bib44","doi-asserted-by":"crossref","first-page":"111","DOI":"10.4193\/Rhino15.284","article-title":"Using postoperative SNOT-22 to help predict the probability of revision sinus surgery","volume":"54","author":"Rudmik","year":"2016","journal-title":"Rhinology"},{"key":"10.1016\/j.jaip.2022.10.030_bib45","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2015-009541","article-title":"Correlation between symptoms and objective findings may improve the symptom-based diagnosis of chronic rhinosinusitis for primary care and epidemiological studies","volume":"5","author":"Park","year":"2015","journal-title":"BMJ Open"},{"key":"10.1016\/j.jaip.2022.10.030_bib46","doi-asserted-by":"crossref","first-page":"718","DOI":"10.3390\/tomography8020059","article-title":"Semi-supervised deep learning semantic segmentation for 3D volumetric computed tomographic scoring of chronic rhinosinusitis: clinical correlations and comparison with Lund-Mackay scoring","volume":"8","author":"Kuo","year":"2022","journal-title":"Tomography"},{"key":"10.1016\/j.jaip.2022.10.030_bib47","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1002\/alr.22920","article-title":"Correlation of chronic rhinosinusitis\u2013related symptoms with computed tomography subsite","volume":"12","author":"Wu","year":"2022","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2022.10.030_bib48","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1002\/lio2.663","article-title":"Radiographic disease severity in chronic rhinosinusitis patients and health care utilization","volume":"6","author":"Mehta","year":"2021","journal-title":"Laryngoscope Investig Otolaryngol"},{"key":"10.1016\/j.jaip.2022.10.030_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2021.103336","article-title":"Artificial intelligence for cellular phenotyping diagnosis of nasal polyps by whole-slide imaging","volume":"66","author":"Wu","year":"2021","journal-title":"EBioMedicine"},{"key":"10.1016\/j.jaip.2022.10.030_bib50","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1007\/s11882-020-00972-y","article-title":"Frequency and clinical utility of olfactory dysfunction in COVID-19: a systematic review and meta-analysis","volume":"20","author":"Pang","year":"2020","journal-title":"Curr Allergy Asthma Rep"},{"key":"10.1016\/j.jaip.2022.10.030_bib51","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1111\/all.14623","article-title":"Regional differences in ACE2 expression in the sinonasal mucosa of adult Chinese patients with chronic rhinosinusitis","volume":"76","author":"Wang","year":"2021","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2022.10.030_bib52","doi-asserted-by":"crossref","first-page":"2904","DOI":"10.1111\/all.14904","article-title":"ACE2 downregulation in olfactory mucosa: eosinophilic rhinosinusitis as COVID-19 protective factor?","volume":"76","author":"Marin","year":"2021","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2022.10.030_bib53","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1146\/annurev-pathol-052016-100401","article-title":"Immunopathogenesis of chronic rhinosinusitis and nasal polyposis","volume":"12","author":"Schleimer","year":"2017","journal-title":"Annu Rev Pathol"},{"key":"10.1016\/j.jaip.2022.10.030_bib54","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1016\/j.jaci.2015.12.1324","article-title":"Inflammatory endotypes of chronic rhinosinusitis based on cluster analysis of biomarkers","volume":"137","author":"Tomassen","year":"2016","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.10.030_bib55","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1016\/j.jaci.2016.06.063","article-title":"Heterogeneous inflammatory patterns in chronic rhinosinusitis without nasal polyps in Chicago, Illinois","volume":"139","author":"Tan","year":"2017","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.10.030_bib56","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/j.jaci.2016.09.048","article-title":"Large-scale gene expression profiling reveals distinct type 2 inflammatory patterns in chronic rhinosinusitis subtypes","volume":"139","author":"Tyler","year":"2017","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.10.030_bib57","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1001\/jama.2015.19330","article-title":"Effect of subcutaneous dupilumab on nasal polyp burden in patients with chronic sinusitis and nasal polyposis: a randomized clinical trial","volume":"315","author":"Bachert","year":"2016","journal-title":"JAMA"},{"key":"10.1016\/j.jaip.2022.10.030_bib58","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1016\/S0140-6736(19)31881-1","article-title":"Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials","volume":"394","author":"Bachert","year":"2019","journal-title":"Lancet"},{"key":"10.1016\/j.jaip.2022.10.030_bib59","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.anai.2021.01.012","article-title":"Dupilumab improves upper and lower airway disease control in chronic rhinosinusitis with nasal polyps and asthma","volume":"126","author":"Laidlaw","year":"2021","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.jaip.2022.10.030_bib60","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1111\/all.15067","article-title":"Efficacy and safety of dupilumab in patients with uncontrolled severe chronic rhinosinusitis with nasal polyps and a clinical diagnosis of NSAID-ERD: results from two randomized placebo-controlled phase 3 trials","volume":"77","author":"Mullol","year":"2022","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2022.10.030_bib61","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1016\/j.jaip.2021.09.037","article-title":"Olfactory outcomes with dupilumab in chronic rhinosinusitis with nasal polyps","volume":"10","author":"Mullol","year":"2022","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.10.030_bib62","doi-asserted-by":"crossref","first-page":"2491","DOI":"10.1111\/all.14308","article-title":"Past, present, and future of anti-IgE biologics","volume":"75","author":"Guntern","year":"2020","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2022.10.030_bib63","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.jaci.2012.07.047","article-title":"Omalizumab is effective in allergic and nonallergic patients with nasal polyps and asthma","volume":"131","author":"Gevaert","year":"2013","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.10.030_bib64","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.jaci.2020.05.032","article-title":"Efficacy and safety of omalizumab in nasal polyposis: 2 randomized phase 3 trials","volume":"146","author":"Gevaert","year":"2020","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.10.030_bib65","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1016\/j.jaci.2021.07.045","article-title":"Long-term efficacy and safety of omalizumab for nasal polyposis in an open-label extension study","volume":"149","author":"Gevaert","year":"2022","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.10.030_bib66","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1016\/j.jaci.2017.05.044","article-title":"Reduced need for surgery in severe nasal polyposis with mepolizumab: randomized trial","volume":"140","author":"Bachert","year":"2017","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.10.030_bib67","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1016\/S2213-2600(21)00097-7","article-title":"Mepolizumab for chronic rhinosinusitis with nasal polyps (SYNAPSE): a randomised, double-blind, placebo-controlled, phase 3 trial","volume":"9","author":"Han","year":"2021","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.jaip.2022.10.030_bib68","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1016\/j.jaci.2011.07.056","article-title":"Mepolizumab, a humanized anti-IL-5 mAb, as a treatment option for severe nasal polyposis","volume":"128","author":"Gevaert","year":"2011","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.10.030_bib69","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1111\/cea.13852","article-title":"Benralizumab effect on severe chronic rhinosinusitis with nasal polyps (CRSwNP): a randomized double-blind placebo-controlled trial","volume":"51","author":"Tversky","year":"2021","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaip.2022.10.030_bib70","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1016\/j.jaci.2021.08.030","article-title":"Efficacy and safety of benralizumab in chronic rhinosinusitis with nasal polyps: a randomized, placebo-controlled trial","volume":"149","author":"Bachert","year":"2022","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.10.030_bib71","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.1111\/all.14809","article-title":"Efficacy and safety of treatment with biologicals for severe chronic rhinosinusitis with nasal polyps: a systematic review for the EAACI guidelines","volume":"76","author":"Agache","year":"2021","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2022.10.030_bib72","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1111\/all.15205","article-title":"Comparing biologicals for severe chronic rhinosinusitis with nasal polyps: a network meta-analysis","volume":"77","author":"Boechat","year":"2022","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2022.10.030_bib73","doi-asserted-by":"crossref","first-page":"1876","DOI":"10.1016\/j.jaip.2022.02.034","article-title":"Comparison of different biologics for treating chronic rhinosinusitis with nasal polyps: a network analysis","volume":"10","author":"Cai","year":"2022","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.10.030_bib74","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.1016\/j.jaip.2021.01.031","article-title":"Indirect treatment comparison of biologics in chronic rhinosinusitis with nasal polyps","volume":"9","author":"Peters","year":"2021","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.10.030_bib75","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1016\/j.jaci.2021.09.009","article-title":"Comparative efficacy and safety of monoclonal antibodies and aspirin desensitization for chronic rhinosinusitis with nasal polyposis: a systematic review and network meta-analysis","volume":"149","author":"Oykhman","year":"2022","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.10.030_bib76","doi-asserted-by":"crossref","first-page":"293","DOI":"10.7326\/0003-4819-154-5-201103010-00003","article-title":"Treatment of chronic rhinosinusitis with nasal polyposis with oral steroids followed by topical steroids: a randomized trial","volume":"154","author":"Vaidyanathan","year":"2011","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jaip.2022.10.030_bib77","doi-asserted-by":"crossref","first-page":"193","DOI":"10.2147\/JAA.S176026","article-title":"Adverse outcomes from initiation of systemic corticosteroids for asthma: long-term observational study","volume":"11","author":"Price","year":"2018","journal-title":"J\u00a0Asthma Allergy"},{"key":"10.1016\/j.jaip.2022.10.030_bib78","doi-asserted-by":"crossref","DOI":"10.1016\/j.waojou.2020.100131","article-title":"Effect of short-course glucocorticoid application on patients with chronic rhinosinusitis with nasal polyps","volume":"13","author":"Xu","year":"2020","journal-title":"World Allergy Organ J"},{"key":"10.1016\/j.jaip.2022.10.030_bib79","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1002\/alr.22894","article-title":"The possibility of short-term hypothalamic-pituitary-adrenal axis suppression with high-volume, high-dose nasal mometasone irrigation in postsurgical patients with chronic rhinosinusitis","volume":"12","author":"Brown","year":"2022","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2022.10.030_bib80","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1002\/alr.22586","article-title":"Randomized clinical trial to evaluate mometasone lavage vs spray for patients with chronic rhinosinusitis without nasal polyps who have not undergone sinus surgery","volume":"10","author":"Jiramongkolchai","year":"2020","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2022.10.030_bib81","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1177\/19458924211033214","article-title":"Effects of fluticasone exhalation delivery system in patients with chronic rhinosinusitis with nasal polyps: a systematic review","volume":"36","author":"Wu","year":"2022","journal-title":"Am J Rhinol Allergy"},{"key":"10.1016\/j.jaip.2022.10.030_bib82","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1002\/alr.22565","article-title":"Drug-eluting implants in chronic rhinosinusitis: an evidence-based review with recommendations","volume":"10","author":"Smith","year":"2020","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2022.10.030_bib83","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1002\/alr.22883","article-title":"Long-acting implantable corticosteroid matrix for chronic rhinosinusitis: Results of LANTERN phase 2 randomized controlled study","volume":"12","author":"Cervin","year":"2022","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2022.10.030_bib84","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.amjoto.2019.03.004","article-title":"The role of doxycycline in the management of chronic rhinosinusitis with nasal polyps","volume":"40","author":"Parasher","year":"2019","journal-title":"Am J Otolaryngol"},{"key":"10.1016\/j.jaip.2022.10.030_bib85","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1002\/alr.21064","article-title":"Antimicrobials and chronic rhinosinusitis with or without polyposis in adults: an evidenced-based review with recommendations","volume":"3","author":"Soler","year":"2013","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2022.10.030_bib86","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1002\/alr.22281","article-title":"Clarithromycin for the treatment of adult chronic rhinosinusitis: a systematic review and meta-analysis","volume":"9","author":"Huang","year":"2019","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2022.10.030_bib87","first-page":"CD011994","article-title":"Systemic and topical antibiotics for chronic rhinosinusitis","volume":"4","author":"Head","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jaip.2022.10.030_bib88","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1016\/j.jaip.2020.02.023","article-title":"Clinical research needs for the management of chronic rhinosinusitis with nasal polyps in the new era of biologics: a National Institute of Allergy and Infectious Diseases Workshop","volume":"8","author":"Naclerio","year":"2020","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.10.030_bib89","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1016\/j.jaci.2020.01.023","article-title":"Clinical factors associated with acute exacerbations of chronic rhinosinusitis","volume":"145","author":"Kwah","year":"2020","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.10.030_bib90","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.jaip.2016.09.015","article-title":"Acute exacerbations mediate quality of life impairment in chronic rhinosinusitis","volume":"5","author":"Phillips","year":"2017","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.10.030_bib91","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1111\/all.13599","article-title":"Diagnosis and management of NSAID-exacerbated respiratory disease (N-ERD)\u2014a EAACI position paper","volume":"74","author":"Kowalski","year":"2019","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2022.10.030_bib92","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/j.jaci.2020.10.043","volume":"147","author":"Stevens","year":"2021","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.10.030_bib93","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1016\/j.jaip.2019.02.037","article-title":"Sinus surgery improves lower respiratory tract reactivity during aspirin desensitization for AERD","volume":"7","author":"Huang","year":"2019","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.10.030_bib94","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1002\/alr.22418","article-title":"Endoscopic sinus surgery improves aspirin treatment response in aspirin-exacerbated respiratory disease patients","volume":"9","author":"Shah","year":"2019","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2022.10.030_bib95","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/S2213-2600(21)00457-4","article-title":"Endoscopic sinus surgery with medical therapy versus medical therapy for chronic rhinosinusitis with nasal polyps: a multicentre, randomised, controlled trial","volume":"10","author":"Lourijsen","year":"2022","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.jaip.2022.10.030_bib96","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.jaci.2022.02.029","article-title":"Prognostic factors for polyp recurrence in chronic rhinosinusitis with nasal polyps","volume":"159","author":"Bai","year":"2022","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.10.030_bib97","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1002\/alr.21739","article-title":"Outcomes of modified endoscopic Lothrop in aspirin-exacerbated respiratory disease with nasal polyposis","volume":"6","author":"Morrissey","year":"2016","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2022.10.030_bib98","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/alr.22505","article-title":"Factors impacting revision surgery in patients with chronic rhinosinusitis with nasal polyposis","volume":"10","author":"Loftus","year":"2020","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2022.10.030_bib99","doi-asserted-by":"crossref","first-page":"5691","DOI":"10.1007\/s00405-022-07470-z","article-title":"Reboot surgery for chronic rhinosinusitis with nasal polyposis: recurrence and smell kinetics","volume":"279","author":"Gomes","year":"2022","journal-title":"Eur Arch Otorhinolaryngol."},{"key":"10.1016\/j.jaip.2022.10.030_bib100","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1016\/j.jaip.2022.02.017","article-title":"Biologicals and endoscopic sinus surgery for severe uncontrolled chronic rhinosinusitis with nasal polyps: an economic perspective","volume":"10","author":"van der Lans","year":"2022","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.10.030_bib101","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1007\/s11882-017-0690-5","article-title":"Economics of chronic rhinosinusitis","volume":"17","author":"Rudmik","year":"2017","journal-title":"Curr Allergy Asthma Rep"},{"key":"10.1016\/j.jaip.2022.10.030_bib102","first-page":"213","article-title":"Direct and indirect costs of adult patients with chronic rhinosinusitis with nasal polyps","volume":"58","author":"Lourijsen","year":"2020","journal-title":"Rhinology"},{"key":"10.1016\/j.jaip.2022.10.030_bib103","first-page":"951","article-title":"Cost-utility analysis of dupilumab for the treatment of chronic rhinosinusitis with nasal polyps (CRSwNP) in Italy","volume":"12","author":"De Corso","year":"2022","journal-title":"J\u00a0Pers Med"},{"key":"10.1016\/j.jaip.2022.10.030_bib104","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1002\/alr.22936","article-title":"Economic evaluation of dupilumab versus endoscopic sinus surgery for the treatment of chronic rhinosinusitis with nasal polyps","volume":"12","author":"Parasher","year":"2022","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2022.10.030_bib105","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1002\/lary.26741","article-title":"Revision rates and time to revision following endoscopic sinus surgery: a large database analysis","volume":"128","author":"Stein","year":"2018","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jaip.2022.10.030_bib106","doi-asserted-by":"crossref","first-page":"2812","DOI":"10.1016\/j.jaip.2019.05.009","article-title":"Associations between inflammatory endotypes and clinical presentations in chronic rhinosinusitis","volume":"7","author":"Stevens","year":"2019","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.10.030_bib107","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1016\/j.jaci.2017.09.009","article-title":"Chronic rhinosinusitis in Asia","volume":"140","author":"Zhang","year":"2017","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.10.030_bib108","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1016\/j.jaci.2016.05.041","article-title":"Diversity of TH cytokine profiles in patients with chronic rhinosinusitis: a multicenter study in Europe, Asia, and Oceania","volume":"138","author":"Wang","year":"2016","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.10.030_bib109","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1016\/j.jaci.2018.10.056","article-title":"Chronic rhinosinusitis in elderly patients is associated with an exaggerated neutrophilic proinflammatory response to pathogenic bacteria","volume":"143","author":"Morse","year":"2019","journal-title":"J\u00a0Allergy Clin Immunol"}],"container-title":["The Journal of Allergy and Clinical Immunology: In Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213219822011321?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213219822011321?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T05:39:13Z","timestamp":1761975553000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213219822011321"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":109,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["S2213219822011321"],"URL":"https:\/\/doi.org\/10.1016\/j.jaip.2022.10.030","relation":{},"ISSN":["2213-2198"],"issn-type":[{"value":"2213-2198","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A Decade of Clinical Advances in Chronic Rhinosinusitis: 2012\u20132022","name":"articletitle","label":"Article Title"},{"value":"The Journal of Allergy and Clinical Immunology: In Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaip.2022.10.030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 American Academy of Allergy, Asthma & Immunology","name":"copyright","label":"Copyright"}]}}