{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T05:49:16Z","timestamp":1761976156489,"version":"build-2065373602"},"reference-count":58,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaci-inpractice.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Allergy and Clinical Immunology: In Practice"],"published-print":{"date-parts":[[2023,3]]},"DOI":"10.1016\/j.jaip.2022.11.039","type":"journal-article","created":{"date-parts":[[2022,12,16]],"date-time":"2022-12-16T11:54:10Z","timestamp":1671191650000},"page":"922-929.e2","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Subendotyping of Dermatophagoides pteronyssinus\u2013Induced Rhinitis and Its Impact on Respiratory Comorbidities"],"prefix":"10.1016","volume":"11","author":[{"given":"Sergio","family":"De Marchi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emanuela","family":"Cecchin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio Umberto","family":"De Marchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico","family":"Iuri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonardo A.","family":"Sechi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaip.2022.11.039_bib1","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.jaip.2016.04.012","article-title":"Chronic rhinosinusitis with nasal polyps","volume":"4","author":"Stevens","year":"2016","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.11.039_bib2","doi-asserted-by":"crossref","first-page":"127","DOI":"10.2147\/JAA.S290424","article-title":"Burden of disease in chronic rhinosinusitis with nasal polyps","volume":"14","author":"Bachert","year":"2021","journal-title":"J\u00a0Asthma Allergy"},{"key":"10.1016\/j.jaip.2022.11.039_bib3","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/j.jaci.2020.01.019","article-title":"Endotypes of chronic rhinosinusitis: impact on management","volume":"145","author":"Cardel","year":"2020","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.11.039_bib4","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1111\/j.1398-9995.2007.01545.x","article-title":"Sinonasal pathology in nonallergic asthma and COPD: \u2018united airway disease\u2019 beyond the scope of allergy","volume":"63","author":"Hens","year":"2008","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2022.11.039_bib5","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1016\/j.jaci.2016.09.008","article-title":"Advances in rhinitis and rhinosinusitis in 2015","volume":"138","author":"Bachert","year":"2016","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.11.039_bib6","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1002\/alr.21258","article-title":"The association between allergy and chronic rhinosinusitis with and without nasal polyps: an evidence-based review with recommendations","volume":"4","author":"Wilson","year":"2014","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2022.11.039_bib7","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1111\/all.12573","article-title":"Phenotypes and endotypes of rhinitis and their impact on management: a PRACTALL report","volume":"70","author":"Papadopoulos","year":"2015","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2022.11.039_bib8","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1111\/all.12002","article-title":"Prevalence and clinical significance of local allergic rhinitis","volume":"67","author":"Rondon","year":"2012","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2022.11.039_bib9","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1111\/all.14206","article-title":"Coexistence of nasal reactivity to allergens with and without IgE-sensitization in allergic rhinitis patients","volume":"75","author":"Eguiluz-Gracia","year":"2020","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2022.11.039_bib10","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1016\/j.jaip.2022.01.005","article-title":"Risk of chronic rhinosinusitis with nasal polyps in endotypes of Dermatophagoides pteronyssinus-induced rhinitis","volume":"10","author":"De Marchi","year":"2022","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.11.039_bib11","doi-asserted-by":"crossref","first-page":"112","DOI":"10.4104\/pcrj.2013.00012","article-title":"Control of Allergic Rhinitis and Asthma Test (CARAT): dissemination and applications in primary care","volume":"22","author":"Azevedo","year":"2013","journal-title":"Prim Care Respir J"},{"key":"10.1016\/j.jaip.2022.11.039_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/all.12040","article-title":"Uncontrolled allergic rhinitis and chronic rhinosinusitis: where do we stand today?","volume":"68","author":"Hellings","year":"2013","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2022.11.039_bib13","first-page":"108","article-title":"International consensus statement on allergy and rhinology: allergic rhinitis","volume":"8","author":"Wise","year":"2018","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2022.11.039_bib14","first-page":"1","article-title":"EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012","volume":"23","author":"Fokkens","year":"2012","journal-title":"Rhinol Suppl"},{"key":"10.1016\/j.jaip.2022.11.039_bib15","first-page":"S22","article-title":"International consensus statement on allergy and rhinology: rhinosinusitis","volume":"6","author":"Orlandi","year":"2016","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaip.2022.11.039_bib16","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/j.otohns.2007.02.004","article-title":"The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict","volume":"137","author":"Hopkins","year":"2007","journal-title":"Otolaryngol-Head and Neck Surg"},{"author":"Global Initiative for Asthma","key":"10.1016\/j.jaip.2022.11.039_bib17"},{"key":"10.1016\/j.jaip.2022.11.039_bib18","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1111\/j.1398-9995.2007.01620.x","article-title":"Allergic rhinitis and its impact on asthma (ARIA) 2008","volume":"63","author":"Bousquet","year":"2008","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2022.11.039_bib19","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1016\/j.jaip.2022.03.019","article-title":"Characterization of asthma by age of onset: a multi-database cohort study","volume":"10","author":"Baan","year":"2022","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2022.11.039_bib20","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1111\/j.1365-2133.1994.tb08530.x","article-title":"The U.K. Working Party\u2019s diagnostic criteria for atopic dermatitis, I: derivation of a minimum set of discriminators for atopic dermatitis","volume":"131","author":"Williams","year":"1994","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaip.2022.11.039_bib21","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.jaad.2013.10.010","article-title":"Guidelines of care for the management of atopic dermatitis: section 1. Diagnosis and assessment of atopic dermatitis","volume":"70","author":"Eichenfield","year":"2014","journal-title":"J\u00a0Am Acad Dermatol"},{"key":"10.1016\/j.jaip.2022.11.039_bib22","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1111\/j.1398-9995.2009.02093.x","article-title":"GA(2)LEN skin test study I: GA(2) LEN harmonization of skin prick testing: novel sensitization patterns for inhalant allergens in Europe","volume":"64","author":"Heinzerling","year":"2009","journal-title":"Allergy"},{"year":"1981","series-title":"Manual of Contact Dermatitis. On behalf of the International Contact Dermatitis Research Group and the North American Contact Dermatitis Group","author":"Fregert","key":"10.1016\/j.jaip.2022.11.039_bib23"},{"key":"10.1016\/j.jaip.2022.11.039_bib24","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/s40413-018-0206-3","article-title":"Brazilian experience with atopy patch tests for Dermatophagoides pteronyssinus, Dermatophagoides farinae and Blomia tropicalis","volume":"11","author":"Souza Lima","year":"2018","journal-title":"World Allergy Organ J"},{"key":"10.1016\/j.jaip.2022.11.039_bib25","first-page":"146","article-title":"Ready-to-use house dust mites atopy patch test (HDM-diallertest), a new screening tool for detection of house dust mites allergy in children","volume":"41","author":"Benhamou","year":"2009","journal-title":"Eur Ann Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.11.039_bib26","first-page":"34","article-title":"Diagnostic performance of the atopy patch test with inhalant allergens","volume":"25","author":"Fuiano","year":"2015","journal-title":"J\u00a0Investig Allergol Clin Immunol"},{"key":"10.1016\/j.jaip.2022.11.039_bib27","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.jim.2012.06.013","article-title":"Optimisation of grass pollen nasal allergen challenge for assessment of clinical and immunological outcomes","volume":"384","author":"Scadding","year":"2012","journal-title":"J\u00a0Immunol Methods"},{"key":"10.1016\/j.jaip.2022.11.039_bib28","first-page":"151","article-title":"Committee report on standardization of rhinomanometry","volume":"22","author":"Clement","year":"1984","journal-title":"Rhinology"},{"key":"10.1016\/j.jaip.2022.11.039_bib29","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1111\/all.13416","article-title":"EAACI Position paper on the standardization of nasal allergen challenges","volume":"73","author":"Auge","year":"2018","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2022.11.039_bib30","first-page":"1","article-title":"Allergen-specific nasal provocation testing: review by the rhinoconjunctivitis committee of the Spanish Society of Allergy and Clinical Immunology","volume":"21","author":"Dordal","year":"2011","journal-title":"J\u00a0Investig Allergol Clin Immunol"},{"key":"10.1016\/j.jaip.2022.11.039_bib31","first-page":"1012","article-title":"Atopy patch tests with different vehicles and allergen concentrations: an approach to standardization","volume":"109","author":"Darsow","year":"2002","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.11.039_bib32","first-page":"677","article-title":"Recognition of pathogenetically relevant house dust mite hypersensitivity in adults with atopic dermatitis: a new approach?","volume":"93","author":"Shah","year":"1995","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.11.039_bib33","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0190-9622(99)70186-6","article-title":"Evaluating the relevance of aeroallergen sensitization in atopic eczema using the tool \u201catopy patch test\u201d: a randomized double blind multicenter study","volume":"40","author":"Darsow","year":"1999","journal-title":"J\u00a0Am Acad Dermatol"},{"key":"10.1016\/j.jaip.2022.11.039_bib34","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/S1081-1206(10)60206-2","article-title":"Relationhip between the atopy patch test and clinical expression of the disease in children with atopic eczema\/dermatitis syndrome and respiratory symptoms","volume":"101","author":"Fuiano","year":"2008","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.jaip.2022.11.039_bib35","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/1939-4551-6-11","article-title":"Seeking allergy when it hides: which are the best fitting tests?","volume":"6","author":"Incorvaia","year":"2013","journal-title":"World Allergy Organ J"},{"key":"10.1016\/j.jaip.2022.11.039_bib36","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1111\/j.1399-3038.2006.00422.x","article-title":"Atopy patch testing in children with asthma and rhinitis symptoms allergic to house dust mite","volume":"17","author":"Guler","year":"2006","journal-title":"Pediatr Allergy Immunol"},{"key":"10.1016\/j.jaip.2022.11.039_bib37","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/2045-7022-3-3","article-title":"The skin prick test\u2014European standards","volume":"3","author":"Heinzerling","year":"2013","journal-title":"Clin Transl Allergy"},{"key":"10.1016\/j.jaip.2022.11.039_bib38","doi-asserted-by":"crossref","first-page":"67","DOI":"10.4193\/RHINOL\/18.021","article-title":"The nasal cycle: a comprehensive review","volume":"1","author":"Pendolino","year":"2018","journal-title":"Rhinol Online"},{"key":"10.1016\/j.jaip.2022.11.039_bib39","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/S0194-59980300123-2","article-title":"Assessment of nasal cycle by acoustic rhinometry and rhinomanometry","volume":"128","author":"Huang","year":"2003","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.jaip.2022.11.039_bib40","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1080\/00016480500401068","article-title":"The effect of allergen provocation on the nasal cycle estimated by acoustic rhinometry","volume":"126","author":"Kim","year":"2006","journal-title":"Acta Otolaryngol"},{"key":"10.1016\/j.jaip.2022.11.039_bib41","doi-asserted-by":"crossref","first-page":"S155","DOI":"10.1016\/j.jaci.2004.09.029","article-title":"Rhinosinusitis: establishing definitions for clinical research and patient care","volume":"114","author":"Meltzer","year":"2004","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.11.039_bib42","doi-asserted-by":"crossref","first-page":"S70","DOI":"10.1016\/S0091-6749(00)90647-X","article-title":"Influx of eosinophils into the maxillary sinus after nasal challenge with allergen [abstract]","volume":"105","author":"Baroody","year":"2000","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.11.039_bib43","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1067\/mai.2001.113046","article-title":"Nasal allergen provocation induces adhesion molecule expression and tissue eosinophilia in upper and lower airways","volume":"107","author":"Braunstahl","year":"2001","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.11.039_bib44","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/s40463-019-0350-y","article-title":"Clinically relevant phenotypes in chronic rhinosinusitis","volume":"48","author":"Grayson","year":"2019","journal-title":"J\u00a0Otolaryngol-Head Neck Surg"},{"key":"10.1016\/j.jaip.2022.11.039_bib45","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/S0091-6749(99)70489-6","article-title":"Molecular mechanisms of CD8+ T cell-mediated delayed hypersensitivity: implications for allergies, asthma, and autoimmunity","volume":"103","author":"Kalish","year":"1999","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.11.039_bib46","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1586\/17476348.2015.1000311","article-title":"Age-of-asthma onset as a determinant of different asthma phenotypes in adults: a systematic review and meta-analysis of the literature","volume":"9","author":"Tan","year":"2015","journal-title":"Expert Rev Respir Med"},{"key":"10.1016\/j.jaip.2022.11.039_bib47","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1097\/DER.0b013e318284da20","article-title":"Atopy patch test to Dermatophagoides mix in a self-selected population in Beijing","volume":"24","author":"Zaho","year":"2013","journal-title":"Dermatitis"},{"key":"10.1016\/j.jaip.2022.11.039_bib48","doi-asserted-by":"crossref","first-page":"317","DOI":"10.3109\/02713683.2012.747617","article-title":"New twists to an old story: novel concepts in the pathogenesis of allergic eye disease","volume":"38","author":"Saban","year":"2013","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.jaip.2022.11.039_bib49","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.1167\/iovs.10-5959","article-title":"\u03b3\u03b4T cells are required for maximal expression of allergic conjunctivitis","volume":"52","author":"Reyes","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jaip.2022.11.039_bib50","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1111\/all.13317","article-title":"EAACI guidelines on allergy immunotherapy: allergic rhinocongiuntivitis","volume":"73","author":"Roberts","year":"2018","journal-title":"Allergy"},{"year":"1981","series-title":"Manual of Contact Dermatitis. On behalf of the International Contact Dermatitis Research Group and the North American Contact Dermatitis Group","author":"Fregert","key":"10.1016\/j.jaip.2022.11.039_bib51"},{"key":"10.1016\/j.jaip.2022.11.039_bib52","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/s40413-018-0206-3","article-title":"Brazilian experience with atopy patch tests for Dermatophagoides pteronyssinus, Dermatophagoides farinae and Blomia tropicalis","volume":"11","author":"Souza Lima","year":"2018","journal-title":"World Allergy Organ J"},{"key":"10.1016\/j.jaip.2022.11.039_bib53","first-page":"146","article-title":"Ready-to-use house dust mites atopy patch test (HDM-diallertest), a new screening tool for detection of house dust mites allergy in children","volume":"41","author":"Benhamou","year":"2009","journal-title":"Eur Ann Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2022.11.039_bib54","first-page":"34","article-title":"Diagnostic performance of the atopy patch test with inhalant allergens","volume":"25","author":"Fuiano","year":"2015","journal-title":"J\u00a0Investig Allergol Clin Immunol"},{"key":"10.1016\/j.jaip.2022.11.039_bib55","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.jim.2012.06.013","article-title":"Optimisation of grass pollen nasal allergen challenge for assessment of clinical and immunological outcomes","volume":"384","author":"Scadding","year":"2012","journal-title":"J\u00a0Immunol Methods"},{"key":"10.1016\/j.jaip.2022.11.039_bib56","first-page":"151","article-title":"Committee report on standardization of rhinomanometry","volume":"22","author":"Clement","year":"1984","journal-title":"Rhinology"},{"key":"10.1016\/j.jaip.2022.11.039_bib57","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1111\/all.13416","article-title":"EAACI Position paper on the standardization of nasal allergen challenges","volume":"73","author":"Auge","year":"2018","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2022.11.039_bib58","first-page":"1","article-title":"Allergen-specific nasal provocation testing: review by the rhinoconjunctivitis committee of the Spanish Society of Allergy and Clinical Immunology","volume":"21","author":"Dordal","year":"2011","journal-title":"J\u00a0Investig Allergol Clin Immunol"}],"container-title":["The Journal of Allergy and Clinical Immunology: In Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213219822012995?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213219822012995?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T05:36:56Z","timestamp":1761975416000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213219822012995"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3]]},"references-count":58,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["S2213219822012995"],"URL":"https:\/\/doi.org\/10.1016\/j.jaip.2022.11.039","relation":{},"ISSN":["2213-2198"],"issn-type":[{"type":"print","value":"2213-2198"}],"subject":[],"published":{"date-parts":[[2023,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Subendotyping of Dermatophagoides pteronyssinus\u2013Induced Rhinitis and Its Impact on Respiratory Comorbidities","name":"articletitle","label":"Article Title"},{"value":"The Journal of Allergy and Clinical Immunology: In Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaip.2022.11.039","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 American Academy of Allergy, Asthma & Immunology","name":"copyright","label":"Copyright"}]}}