{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:28:44Z","timestamp":1786991324159,"version":"build-2736575974"},"reference-count":48,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["jaci-inpractice.org","clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Allergy and Clinical Immunology: In Practice"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1016\/j.jaip.2023.08.039","type":"journal-article","created":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T05:09:50Z","timestamp":1693717790000},"page":"3645-3649","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Multiple Chemical Sensitivity\/Idiopathic Environmental Intolerance: A Practical Approach to Diagnosis and Management"],"prefix":"10.1016","volume":"11","author":[{"given":"Karen E.","family":"Binkley","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaip.2023.08.039_bib1","series-title":"Idiopathic environmental intolerance (multiple chemical sensitivity; environmental illness). Merck Manual, Professional Version","author":"Black","year":"2002"},{"key":"10.1016\/j.jaip.2023.08.039_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpsychores.2020.109964","article-title":"The impact of multiple chemical sensitivity on people's social and occupational functioning; a systematic review of qualitative research studies","volume":"132","author":"Driesen","year":"2020","journal-title":"J\u00a0Psychosom Res"},{"key":"10.1016\/j.jaip.2023.08.039_bib3","doi-asserted-by":"crossref","first-page":"235","DOI":"10.2165\/00139709-200322040-00005","article-title":"Idiopathic environmental intolerance: part 1: a causation analysis applying Bradford Hill\u2019s criteria to the toxicogenic theory","volume":"22","author":"Staudenmayer","year":"2003","journal-title":"Toxicol Rev"},{"key":"10.1016\/j.jaip.2023.08.039_bib4","doi-asserted-by":"crossref","first-page":"247","DOI":"10.2165\/00139709-200322040-00006","article-title":"Idiopathic environmental intolerance: part 2: a causation analysis applying Bradford Hill\u2019s criteria to the psychogenic theory","volume":"22","author":"Staudenmayer","year":"2003","journal-title":"Toxicol Rev"},{"key":"10.1016\/j.jaip.2023.08.039_bib5","first-page":"30","article-title":"Panic attacks induced by olfactory stimuli: an emerging paradigm for idiopathic environmental intolerance (multiple chemical sensitivity)","author":"Binkley","year":"2003","journal-title":"Can Psychiatr Assoc Bull"},{"key":"10.1016\/j.jaip.2023.08.039_bib6","series-title":"Environmental illness: myth and reality","author":"Staudenmayer","year":"1999"},{"key":"10.1016\/j.jaip.2023.08.039_bib7","first-page":"557","article-title":"The relationship of mental disorders and idiopathic environmental intolerance. State of the art reviews","volume":"15","author":"Black","year":"2000","journal-title":"J\u00a0Occup Med"},{"key":"10.1016\/j.jaip.2023.08.039_bib8","doi-asserted-by":"crossref","first-page":"97","DOI":"10.7326\/0003-4819-119-2-199307150-00001","article-title":"Immunologic, psychological and neuropsychological factors in multiple chemical sensitivity: a controlled study","volume":"119","author":"Simon","year":"1993","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jaip.2023.08.039_bib9","doi-asserted-by":"crossref","first-page":"3166","DOI":"10.1001\/jama.1990.03450240068042","article-title":"Environmental illness: a controlled study of 26 subjects with \u201c20th century disease.\u201d","volume":"264","author":"Black","year":"1990","journal-title":"JAMA"},{"key":"10.1016\/j.jaip.2023.08.039_bib10","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1097\/00006842-199601000-00007","article-title":"A\u00a0controlled comparison of multiple chemical sensitivities and chronic fatigue syndrome","volume":"58","author":"Fiedler","year":"1996","journal-title":"Psychosom Med"},{"key":"10.1016\/j.jaip.2023.08.039_bib11","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/S0022-3999(01)00250-1","article-title":"Psychological features of patients with idiopathic environmental intolerance","volume":"51","author":"Poonai","year":"2001","journal-title":"J\u00a0Psychosom Res"},{"key":"10.1016\/j.jaip.2023.08.039_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpsychores.2022.110808","article-title":"Symptoms of idiopathic environmental intolerance associated with chemicals (IEI-C) are positively associated with perceptual anomalies","volume":"157","author":"Speck","year":"2022","journal-title":"J\u00a0Psychosom Res"},{"key":"10.1016\/j.jaip.2023.08.039_bib13","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0246461","article-title":"Multiple chemical sensitivity described in the Danish general population: cohort characteristics and the importance of screening for functional somatic syndrome comorbidity\u2014The DanFunD study","volume":"16","author":"Dantoft","year":"2021","journal-title":"PLoS One"},{"key":"10.1016\/j.jaip.2023.08.039_bib14","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1067\/mai.2001.114798","article-title":"Idiopathic environmental intolerance: increased prevalence of panic disorder-associated cholecystokinin B receptor allele 7","volume":"107","author":"Binkley","year":"2001","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2023.08.039_bib15","first-page":"538","article-title":"Adult sequelae of childhood abuse presenting as environmental illness","volume":"73","author":"Staudenmayer","year":"1993","journal-title":"Ann Allergy"},{"key":"10.1016\/j.jaip.2023.08.039_bib16","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1006\/rtph.1993.1043","article-title":"Double blind provocative chamber challenges in 20 patients presenting with \u201cmultiple chemical sensitivity.\u201d","volume":"18","author":"Staudenmeyer","year":"1998","journal-title":"Regul Toxicol Pharmacol"},{"key":"10.1016\/j.jaip.2023.08.039_bib17","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/S0091-6749(97)70067-8","article-title":"Provocative challenges in patients with multiple chemical sensitivity","volume":"99","author":"Leznoff","year":"1997","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2023.08.039_bib18","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/S0091-6749(97)70086-1","article-title":"Panic responses to sodium lactate in patients with multiple chemical sensitivity syndrome","volume":"99","author":"Binkley","year":"1997","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2023.08.039_bib19","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/S0091-6749(00)90088-5","article-title":"Carbon dioxide inhalational challenges in idiopathic environmental intolerance","volume":"105","author":"Poonai","year":"2000","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2023.08.039_bib20","first-page":"684","article-title":"Conditioning of physical symptoms after neurotoxic exposure","volume":"30","author":"Bolla-Wilson","year":"1988","journal-title":"J\u00a0Occup Med"},{"key":"10.1016\/j.jaip.2023.08.039_bib21","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1176\/ajp.144.8.1056","article-title":"Panic disorder precipitated by exposure to organic solvents in the workplace","volume":"144","author":"Dager","year":"1987","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.jaip.2023.08.039_bib22","first-page":"565","article-title":"Behavioural sensitization to irritant\/odorants after acute overexposures","volume":"30","author":"Shusterman","year":"1988","journal-title":"J\u00a0Occup Med"},{"key":"10.1016\/j.jaip.2023.08.039_bib23","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1136\/oem.56.5.295","article-title":"Acquisition and extinction of somatic symptoms in response to odours: a Pavlovian paradigm relevant to multiple chemical sensitivity","volume":"56","author":"Van den Bergh","year":"1999","journal-title":"Occ Environ Med"},{"key":"10.1016\/j.jaip.2023.08.039_bib24","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1097\/00006842-200011000-00003","article-title":"Generalization of acquired somatic symptoms in response to odors: a pavlovian perspective on multiple chemical sensitivity","volume":"62","author":"Devriese","year":"2000","journal-title":"Psychosom Med"},{"key":"10.1016\/j.jaip.2023.08.039_bib25","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.psychres.2017.09.018","article-title":"Both anxiety and joint laxity determine the olfactory features in panic disorder","volume":"262","author":"Bur\u00f3n","year":"2018","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.jaip.2023.08.039_bib26","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.jad.2015.01.049","article-title":"Olfactory functioning in panic disorder","volume":"175","author":"Bur\u00f3n","year":"2015","journal-title":"J\u00a0Affect Disord"},{"key":"10.1016\/j.jaip.2023.08.039_bib27","doi-asserted-by":"crossref","DOI":"10.1371\/annotation\/e2406113-a289-49f6-b3d9-88d09d385d50","article-title":"Altered olfactory processing of stress-related body odors and artificial odors in patients with panic disorder","volume":"8","author":"Wintermann","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jaip.2023.08.039_bib28","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1002\/ajim.20351","article-title":"Cognitive impairment and olfactory panic from occupational exposure to VOCs","volume":"49","author":"Reinhartz","year":"2006","journal-title":"Am J Ind Med"},{"key":"10.1016\/j.jaip.2023.08.039_bib29","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.bbr.2006.05.021","article-title":"Effects of medial amygdala inactivation on a panic-related behavior","volume":"172","author":"Herdade","year":"2006","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.jaip.2023.08.039_bib30","doi-asserted-by":"crossref","first-page":"101","DOI":"10.3109\/15563659509000457","article-title":"Multiple chemical sensitivities\u2013a syndrome of pseudotoxicity manifest as exposure perceived symptoms","volume":"33","author":"Kurt","year":"1995","journal-title":"J\u00a0Toxicol Clin Toxicol"},{"key":"10.1016\/j.jaip.2023.08.039_bib31","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.genhosppsych.2004.04.007","article-title":"Olfactory-triggered panic attacks among Cambodian refugees attending a psychiatric clinic","volume":"26","author":"Hinton","year":"2004","journal-title":"Gen Hosp Psychiatry"},{"key":"10.1016\/j.jaip.2023.08.039_bib32","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1177\/1363461504043564","article-title":"Olfactory-triggered panic attacks among Khmer refugees: a contextual approach","volume":"41","author":"Hinton","year":"2004","journal-title":"Transcult Psychiatry"},{"key":"10.1016\/j.jaip.2023.08.039_bib33","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.jpsychores.2009.03.009","article-title":"Resistance to extinction in an odor\u201320% CO2 inhalation paradigm: further evidence for a symptom learning account of multiple chemical sensitivity","volume":"68","author":"Meulders","year":"2010","journal-title":"J\u00a0Psychosom Res"},{"key":"10.1016\/j.jaip.2023.08.039_bib34","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1111\/j.1749-6632.2001.tb05831.x","article-title":"Acquiring symptoms in response to odors: a learning perspective on multiple chemical sensitivity","volume":"933","author":"Van den Bergh","year":"2001","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.jaip.2023.08.039_bib35","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1080\/15287390801985562","article-title":"Psychological predictors of short-and medium term outcome in individuals with idiopathic environmental intolerance (IEI) and individuals with somatoform disorders","volume":"71","author":"Bailer","year":"2008","journal-title":"J\u00a0Toxicol Environ Health A"},{"key":"10.1016\/j.jaip.2023.08.039_bib36","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1097\/01.psy.0000174170.66109.b7","article-title":"Evidence for overlap between idiopathic environmental intolerance and somatoform disorders","volume":"67","author":"Bailer","year":"2005","journal-title":"Psychosom Med"},{"key":"10.1016\/j.jaip.2023.08.039_bib37","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1017\/S0033291706009354","article-title":"Syndrome stability and psychological predictors of symptom severity in idiopathic environmental intolerance and somatoform disorders","volume":"37","author":"Bailer","year":"2007","journal-title":"Psychol Med"},{"key":"10.1016\/j.jaip.2023.08.039_bib38","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1097\/MOO.0b013e328259c360","article-title":"Multiple chemical sensitivities","volume":"15","author":"Das-Munshi","year":"2007","journal-title":"Curr Opin Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.jaip.2023.08.039_bib39","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1177\/136346150003700402","article-title":"Occupational mass psychogenic illness: a transcultural perspective","volume":"37","author":"Bartholomew","year":"2000","journal-title":"Transcultural Psychiatry"},{"key":"10.1016\/j.jaip.2023.08.039_bib40","series-title":"Sick buildings: definition, diagnosis and mitigation","author":"Godish","year":"2018"},{"key":"10.1016\/j.jaip.2023.08.039_bib41","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/0005-7916(94)90020-5","article-title":"Behavioural treatment of phobic avoidance in multiple chemical sensitivity","volume":"25","author":"Guglielmi","year":"1994","journal-title":"J\u00a0Behav Ther Exp Psychiatry"},{"key":"10.1016\/j.jaip.2023.08.039_bib42","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/S0033-3182(98)71335-0","article-title":"Multiple chemical sensitivity","volume":"39","author":"Stenn","year":"1998","journal-title":"Psychosomatics"},{"key":"10.1016\/j.jaip.2023.08.039_bib43","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/S0033-3182(98)71289-7","article-title":"Successful outcome in a patient with chemical sensitivity. Treatment with psychological desensitization and selective serotonin reuptake inhibitor","volume":"39","author":"Stenn","year":"1998","journal-title":"Psychosomatics"},{"issue":"suppl 1","key":"10.1016\/j.jaip.2023.08.039_bib44","first-page":"587","article-title":"\u201cSpecialized\u201d psychiatric referral: improved outcome in patients with multiple chemical sensitivity","volume":"101","author":"Binkley","year":"1998","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaip.2023.08.039_bib45","doi-asserted-by":"crossref","first-page":"53","DOI":"10.2147\/JMDH.S5220","article-title":"A\u00a0controlled study of the effect of a mindfulness-based stress reduction technique in women with multiple chemical sensitivity, chronic fatigue syndrome, and fibromyalgia","volume":"7","author":"Sampalli","year":"2009","journal-title":"J\u00a0Multidiscip Healthc"},{"key":"10.1016\/j.jaip.2023.08.039_bib46","first-page":"706","article-title":"Multiple chemical sensitivity is for real [in Finnish]","volume":"127","author":"Hannuksela","year":"2011","journal-title":"Duodecim"},{"key":"10.1016\/j.jaip.2023.08.039_bib47","first-page":"e27","article-title":"Stable remission of multiple chemical sensitivity syndrome and major depression with citalopram and 1-month deep transcranial magnetic stimulation: a case report","volume":"33","author":"Del Casale","year":"2017","journal-title":"J\u00a0ECT"},{"key":"10.1016\/j.jaip.2023.08.039_bib48","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1097\/PSY.0000000000000679","article-title":"Exploratory investigation of a brief cognitive behavioral intervention and transcranial direct current stimulation on odor sensitivity","volume":"81","author":"Houghton","year":"2019","journal-title":"Psychosom Med"}],"container-title":["The Journal of Allergy and Clinical Immunology: In Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213219823009613?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213219823009613?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T01:23:55Z","timestamp":1716427435000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213219823009613"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":48,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["S2213219823009613"],"URL":"https:\/\/doi.org\/10.1016\/j.jaip.2023.08.039","relation":{},"ISSN":["2213-2198"],"issn-type":[{"value":"2213-2198","type":"print"}],"subject":[],"published":{"date-parts":[[2023,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multiple Chemical Sensitivity\/Idiopathic Environmental Intolerance: A Practical Approach to Diagnosis and Management","name":"articletitle","label":"Article Title"},{"value":"The Journal of Allergy and Clinical Immunology: In Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaip.2023.08.039","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 American Academy of Allergy, Asthma & Immunology","name":"copyright","label":"Copyright"}]}}