{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T20:51:03Z","timestamp":1791406263110,"version":"4.3.3"},"reference-count":10,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaci-inpractice.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Allergy and Clinical Immunology: In Practice"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.jaip.2026.07.047","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T09:40:31Z","timestamp":1791366031000},"page":"2319-2321","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Beyond Eosinophils: Predicting Mucus Plugs in Asthma"],"prefix":"10.1016","volume":"14","author":[{"given":"Maria A.","family":"Forero Molina","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James G.","family":"Krings","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6469-1926","authenticated-orcid":false,"given":"Ting Fan","family":"Leung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaip.2026.07.047_bib1","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.1093\/ajrccm\/aamag309","article-title":"Airway mucus plugs in asthma and COPD: pathobiology, imaging, and implications for clinical trials","volume":"212","author":"Bosma","year":"2026","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaip.2026.07.047_bib2","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1007\/s40265-026-02294-1","article-title":"Mucus as a treatable trait in chronic airway diseases","volume":"86","author":"Cazzola","year":"2026","journal-title":"Drugs"},{"key":"10.1016\/j.jaip.2026.07.047_bib3","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.jaip.2022.09.008","article-title":"Clinical associations of mucus plugging in moderate to severe asthma","volume":"11","author":"Chan","year":"2023","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2026.07.047_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaip.2026.06.017","article-title":"Development and validation of clinical scoring system to estimate mucus plug presence in asthma","author":"Sasada","year":"2026","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaip.2026.07.047_bib5","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1111\/all.70197","article-title":"The role of biologics in reducing mucous plug burden in asthma","volume":"81","author":"Poto","year":"2026","journal-title":"Allergy"},{"key":"10.1016\/j.jaip.2026.07.047_bib6","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1164\/rccm.202410-1894OC","article-title":"Effect of dupilumab on mucus burden in patients with moderate-to-severe asthma: the VESTIGE trial","volume":"212","author":"Porsbjerg","year":"2026","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaip.2026.07.047_bib7","doi-asserted-by":"crossref","DOI":"10.1056\/EVIDoa2300135","article-title":"Tezepelumab and mucus plugs in patients with moderate-to-severe asthma","volume":"2","author":"Nordenmark","year":"2023","journal-title":"NEJM Evid"},{"key":"10.1016\/j.jaip.2026.07.047_bib8","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1172\/JCI95693","article-title":"Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction","volume":"128","author":"Dunican","year":"2018","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jaip.2026.07.047_bib9","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.1001\/jama.2023.2065","article-title":"Airway occluding mucus plugs and mortality in patients with chronic obstructive pulmonary disease","volume":"329","author":"Diaz","year":"2023","journal-title":"JAMA"},{"key":"10.1016\/j.jaip.2026.07.047_bib10","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1152\/physrev.00004.2021","article-title":"Physiology and pathophysiology of human airway mucus","volume":"102","author":"Hill","year":"2022","journal-title":"Physiol Rev"}],"container-title":["The Journal of Allergy and Clinical Immunology: In Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213219826006446?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213219826006446?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T19:59:42Z","timestamp":1791403182000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213219826006446"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":10,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["S2213219826006446"],"URL":"https:\/\/doi.org\/10.1016\/j.jaip.2026.07.047","relation":{},"ISSN":["2213-2198"],"issn-type":[{"value":"2213-2198","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Beyond Eosinophils: Predicting Mucus Plugs in Asthma","name":"articletitle","label":"Article Title"},{"value":"The Journal of Allergy and Clinical Immunology: In Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaip.2026.07.047","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 American Academy of Allergy, Asthma & Immunology","name":"copyright","label":"Copyright"}]}}