{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:01:26Z","timestamp":1761512486248,"version":"build-2065373602"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2007,12,21]],"date-time":"2007-12-21T00:00:00Z","timestamp":1198195200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["alz-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Alzheimer's &amp;amp; Dementia"],"published-print":{"date-parts":[[2008,7]]},"abstract":"<jats:sec><jats:label\/><jats:p>There are persistent disparities in Alzheimer's disease by race and ethnicity that are not well understood. The emphasis given to seeking a genetic basis for racial differences might be a distraction from the more relevant issue of identifying preventable causes of Alzheimer's disease. The majority of Alzheimer's disease cases are diagnosed as the late onset type and are unlikely to be inherited. Late onset Alzheimer's disease cases, therefore, more likely represent variations in gene expression than gene frequency. Although conceptual and methodologic problems have limited our understanding of this relationship, race\u2010based studies provide important opportunities to understand the environmental factors associated with gene expression. Improving our understanding of the factors associated with race and ethnicity might help to clarify the epidemiology and course of Alzheimer's disease.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.jalz.2007.10.014","type":"journal-article","created":{"date-parts":[[2007,12,26]],"date-time":"2007-12-26T11:24:39Z","timestamp":1198668279000},"page":"239-241","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Commentary on \u201cPerspective on race and ethnicity in Alzheimer's disease research\u201d"],"prefix":"10.1002","volume":"4","author":[{"given":"Derek M.","family":"Griffith","sequence":"first","affiliation":[{"name":"Department of Health Behavior and Health Education University of Michigan School of Public Health Ann Arbor MI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick A.","family":"Griffith","sequence":"additional","affiliation":[{"name":"Clinical Research Center Department of Neurology Meharry Medical College Nashville TN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,12,21]]},"reference":[{"key":"e_1_2_3_2_2","first-page":"95","volume-title":"Critical perspectives on racial and ethnic differences in health in late life","author":"Manly J.J.","year":"2004"},{"key":"e_1_2_3_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature02621"},{"key":"e_1_2_3_4_2","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.91.7.1049"},{"key":"e_1_2_3_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrg1452"},{"key":"e_1_2_3_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsb022863"},{"issue":"3","key":"e_1_2_3_7_2","first-page":"iii26","article-title":"Disentangling race and socioeconomic status: a key to understanding health inequalities","volume":"82","author":"LaVeist T.A.","year":"2005","journal-title":"J Urban Health"},{"key":"e_1_2_3_8_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.publhealth.24.100901.140927"},{"key":"e_1_2_3_9_2","doi-asserted-by":"publisher","DOI":"10.2190\/LKDF-UJQ5-W1KU-GLR1"},{"volume-title":"The unequal burden of cancer: an assessment of NIH research and programs for ethnic minorities and the medically underserved","year":"1999","author":"Committee on Cancer Research Among Minorities and the Medically Underserved, Institute of Medicine","key":"e_1_2_3_10_2"},{"key":"e_1_2_3_11_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.328.7447.1070"},{"key":"e_1_2_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2007.01.010"},{"key":"e_1_2_3_13_2","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.annepidem.2005.10.003","article-title":"The association of race with frailty: the Cardiovascular Health Study","volume":"16","author":"Kaufman J.S.","year":"2006","journal-title":"Ann Epidemiol"},{"key":"e_1_2_3_14_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1996.00550100071017"},{"key":"e_1_2_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67889-0"},{"key":"e_1_2_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1064-7481(12)61668-6"},{"key":"e_1_2_3_17_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.3.329"},{"key":"e_1_2_3_18_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.285.6.739"},{"key":"e_1_2_3_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410380319"},{"key":"e_1_2_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2007.01.021"},{"issue":"2","key":"e_1_2_3_21_2","doi-asserted-by":"crossref","first-page":"S80","DOI":"10.1097\/00002093-200200002-00008","article-title":"Challenges in cognitive assessment of African Americans in research on Alzheimer disease","volume":"16","author":"Whitfield K.E.","year":"2002","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"e_1_2_3_22_2","doi-asserted-by":"publisher","DOI":"10.1586\/14737175.7.7.887"},{"key":"e_1_2_3_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0033-3549(04)50068-7"}],"container-title":["Alzheimer's &amp; 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