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Microhemorrhages and superficial siderosis were assessed at baseline and on all available MRIs at 3, 6, and 12 months. \u03b2\u2010amyloid load was assessed with <jats:sup>18<\/jats:sup>F\u2010florbetapir positron emission tomography.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Prevalence of superficial siderosis was 1% and prevalence of microhemorrhages was 25% increasing with age (<jats:italic>P<\/jats:italic> &lt; .001) and \u03b2\u2010amyloid load (<jats:italic>P<\/jats:italic> &lt; .001). Topographic densities of microhemorrhages were highest in the occipital lobes and lowest in the deep\/infratentorial regions. A greater number of microhemorrhages at baseline was associated with a greater annualized rate of additional microhemorrhages by last follow\u2010up (rank correlation\u00a0=\u00a00.49; <jats:italic>P<\/jats:italic> &lt; .001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Focal hemosiderin deposits are relatively common in the ADNI cohort and are associated with \u03b2\u2010amyloid load.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.jalz.2012.10.011","type":"journal-article","created":{"date-parts":[[2013,1,30]],"date-time":"2013-01-30T18:19:24Z","timestamp":1359569964000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Focal hemosiderin deposits and \u03b2\u2010amyloid load in the ADNI cohort"],"prefix":"10.1002","volume":"9","author":[{"given":"Kejal","family":"Kantarci","sequence":"first","affiliation":[{"name":"Department of Radiology Mayo Clinic Rochester MN 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