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Observed Medicaid payments were used to calculate savings from delayed institutionalization, adjusting for cost offsets resulting from concurrent changes in use of other medical services.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Initiation of existing therapies at earliest symptomatic onset is predicted to delay institutionalization by 91 days, reducing Medicaid costs by $19,108\/institutionalized patient. Incorporating an 18.5% cost offset from increased use of other medical services as well as drug costs associated with earlier treatment results in net savings of $12,687\/patient. Projected annual Medicaid savings exceed $1\u00a0billion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Earlier treatment leads to a small delay in institutionalization among AD patients, resulting in significant costs savings to Medicaid.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.jalz.2013.01.015","type":"journal-article","created":{"date-parts":[[2013,5,2]],"date-time":"2013-05-02T12:31:18Z","timestamp":1367497878000},"page":"214-224","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":49,"title":["Implications of early treatment among Medicaid patients with Alzheimer's disease"],"prefix":"10.1002","volume":"10","author":[{"given":"David S.","family":"Geldmacher","sequence":"first","affiliation":[{"name":"Department of Neurology, School of Medicine University of Alabama at Birmingham Birmingham AL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noam Y.","family":"Kirson","sequence":"additional","affiliation":[{"name":"Analysis Group, Inc. 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