{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T19:47:25Z","timestamp":1793216845605,"version":"4.5.0"},"reference-count":43,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2017,2,18]],"date-time":"2017-02-18T00:00:00Z","timestamp":1487376000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001961","name":"AXA Research Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001961","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["alz-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Alzheimer's &amp;amp; Dementia"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The International Working Group recommended the Free and Cued Selective Reminding Test (FCSRT) as a sensitive detector of the amnesic syndrome of the hippocampal type in typical Alzheimer's disease (AD). But does it differentiate AD from other neurodegenerative diseases?<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We assessed the FCSRT and cerebrospinal fluid (CSF) AD biomarkers in 992 cases. Experts, blinded to biomarker data, attributed in 650 cases a diagnosis of typical AD, frontotemporal dementia, posterior cortical atrophy, Lewy body disease, progressive supranuclear palsy, corticobasal syndrome, primary progressive aphasias, \u201csubjective cognitive decline,\u201d or depression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The FCSRT distinguished typical AD from all other conditions with a sensitivity of 100% and a specificity of 75%. Non\u2010AD neurodegenerative diseases with positive AD CSF biomarkers (\u201catypical AD\u201d) did not have lower FCSRT scores than those with negative biomarkers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>The FCSRT is a reliable tool for diagnosing typical AD among various neurodegenerative diseases. At an individual level, however, its specificity is not absolute. Our findings also widen the spectrum of atypical AD to multiple neurodegenerative conditions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.jalz.2016.12.014","type":"journal-article","created":{"date-parts":[[2017,2,21]],"date-time":"2017-02-21T06:30:46Z","timestamp":1487658646000},"page":"913-923","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":84,"title":["Free and Cued Selective Reminding Test \u2013 accuracy for the differential diagnosis of Alzheimer's and neurodegenerative diseases: A large\u2010scale biomarker\u2010characterized monocenter cohort study (ClinAD)"],"prefix":"10.1002","volume":"13","author":[{"given":"Marc","family":"Teichmann","sequence":"first","affiliation":[{"name":"Department of Neurology Institut de la m\u00e9moire et de la maladie d'Alzheimer, Centre de R\u00e9f\u00e9rence \u2018D\u00e9mences Rares\u2019, H\u00f4pital de la Piti\u00e9\u2010Salp\u00eatri\u00e8re, AP\u2010HP  Paris France"},{"name":"Institut du Cerveau et de la Moelle Epini\u00e8re (ICM) ICM\u2010INSERM 1127, FrontLab  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phane","family":"Epelbaum","sequence":"additional","affiliation":[{"name":"Department of Neurology Institut de la m\u00e9moire et de la maladie d'Alzheimer, Centre de R\u00e9f\u00e9rence \u2018D\u00e9mences Rares\u2019, H\u00f4pital de la Piti\u00e9\u2010Salp\u00eatri\u00e8re, AP\u2010HP  Paris France"},{"name":"Institut du Cerveau et de la Moelle Epini\u00e8re (ICM), ICM\u2010INSERM 1127 Team Alzheimer's and Prions Diseases  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dalila","family":"Samri","sequence":"additional","affiliation":[{"name":"Department of Neurology Institut de la m\u00e9moire et de la maladie d'Alzheimer, Centre de R\u00e9f\u00e9rence \u2018D\u00e9mences Rares\u2019, H\u00f4pital de la Piti\u00e9\u2010Salp\u00eatri\u00e8re, AP\u2010HP  Paris 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