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Black decedents had a lower Braak tangle stage (stage V) and higher frequency of coexisting hippocampal sclerosis (21%); however, only hippocampal sclerosis differences survived adjustment for sex, age at onset, and disease duration. Neither Thal amyloid phase nor coexisting Lewy body disease differed across ethnoracial groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Despite a smaller sample size, Hispanics demonstrated longer disease duration with Alzheimer's disease, but not greater lifespan. Neuropathologic differences across ethnoracial groups supported differences in tau pathology distribution and coexisting hippocampal sclerosis, which may impact biomarker studies.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.jalz.2018.12.013","type":"journal-article","created":{"date-parts":[[2019,2,18]],"date-time":"2019-02-18T04:04:45Z","timestamp":1550462685000},"page":"635-643","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":55,"title":["Ethnoracial differences in Alzheimer's disease from the FLorida Autopsied Multi\u2010Ethnic (FLAME) cohort"],"prefix":"10.1002","volume":"15","author":[{"given":"Octavio A.","family":"Santos","sequence":"first","affiliation":[{"name":"Department of Psychiatry and Psychology Mayo Clinic Jacksonville FL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Otto","family":"Pedraza","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Psychology Mayo Clinic 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