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Finnish Geriatric Intervevntion Study to Prevent Cognitive Impairment and Disability participants received a 2\u2010year multidomain lifestyle intervention (physical training, cognitive training, nutritional counseling, and cardiovascular monitoring). Multidomain Alzheimer Preventive Trial participants received a 3\u2010year multidomain lifestyle intervention (cognitive training, physical activity counseling, and nutritional counseling) with either an omega\u20103 supplement or placebo.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Adherence decreased with increasing intervention complexity and intensity: it was highest for cardiovascular monitoring, nutritional counseling, and the omega\u20103 supplement, and lowest for unsupervised computer\u2010based cognitive training. The most consistent baseline predictors of adherence were smoking and depressive symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Reducing participant burden, while ensuring that technological tools are suitable for older individuals, maintaining face\u2010to\u2010face contacts, and taking into account participant characteristics may increase adherence in future trials.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.jalz.2019.03.005","type":"journal-article","created":{"date-parts":[[2019,4,30]],"date-time":"2019-04-30T00:34:26Z","timestamp":1556584466000},"page":"729-741","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":118,"title":["Adherence to multidomain interventions for dementia prevention: Data from the FINGER and MAPT trials"],"prefix":"10.1002","volume":"15","author":[{"given":"Nicola","family":"Coley","sequence":"first","affiliation":[{"name":"INSERM\u2010University of Toulouse UMR 1027 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