{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T04:06:00Z","timestamp":1792037160142,"version":"4.4.0"},"reference-count":45,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","jamda.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Medical Directors Association"],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.1016\/j.jamda.2015.12.092","type":"journal-article","created":{"date-parts":[[2016,2,4]],"date-time":"2016-02-04T14:00:49Z","timestamp":1454594449000},"page":"482-490","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":273,"title":["Poor Gait Performance and Prediction of Dementia: Results From a\u00a0Meta-Analysis"],"prefix":"10.1016","volume":"17","author":[{"given":"Olivier","family":"Beauchet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9dric","family":"Annweiler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele L.","family":"Callisaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne-Marie","family":"De Cock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorunn L.","family":"Helbostad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reto W.","family":"Kressig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Velandai","family":"Srikanth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Paul","family":"Steinmetz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helena M.","family":"Blumen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joe","family":"Verghese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilles","family":"Allali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jamda.2015.12.092_bib1","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1056\/NEJMoa020441","article-title":"Abnormality of gait as a predictor of non-Alzheimer's dementia","volume":"347","author":"Verghese","year":"2002","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jamda.2015.12.092_bib2","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1111\/j.1532-5415.1996.tb06417.x","article-title":"Gait disorders in older adults","volume":"44","author":"Alexander","year":"1996","journal-title":"J\u00a0Am Geriatr Soc"},{"key":"10.1016\/j.jamda.2015.12.092_bib3","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1001\/archneur.1994.00540180051013","article-title":"Comparison of neurologic changes in 'successfully aging' persons vs the total aging population","volume":"51","author":"Odenheimer","year":"1994","journal-title":"Arch Neurol"},{"key":"10.1016\/j.jamda.2015.12.092_bib4","first-page":"135","article-title":"Classification of gait and balance disorders","volume":"87","author":"Nutt","year":"2001","journal-title":"Adv Neurol"},{"key":"10.1016\/j.jamda.2015.12.092_bib5","doi-asserted-by":"crossref","first-page":"2127","DOI":"10.1111\/j.1532-5415.2012.04209.x","article-title":"Gait and cognition: A complementary approach to understanding brain function and the risk of falling","volume":"60","author":"Montero-Odasso","year":"2012","journal-title":"J\u00a0Am Geriatr Soc"},{"key":"10.1016\/j.jamda.2015.12.092_bib6","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/j.neubiorev.2009.10.005","article-title":"Motor control and aging: Links to age-related brain structural, functional, and biochemical effects","volume":"34","author":"Seidler","year":"2010","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.jamda.2015.12.092_bib7","doi-asserted-by":"crossref","first-page":"e99318","DOI":"10.1371\/journal.pone.0099318","article-title":"Motor phenotype of decline in cognitive performance among community-dwellers without dementia: Population-based study and meta-analysis","volume":"9","author":"Beauchet","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.jamda.2015.12.092_bib8","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/S1474-4422(14)70090-0","article-title":"Advancing research diagnostic criteria for Alzheimer's disease: The IWG-2 criteria","volume":"13","author":"Dubois","year":"2014","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.jamda.2015.12.092_bib9","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1111\/joim.12199","article-title":"Harmonized diagnostic criteria for Alzheimer's disease: Recommendations","volume":"275","author":"Morris","year":"2014","journal-title":"J\u00a0Intern Med"},{"key":"10.1016\/j.jamda.2015.12.092_bib10","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.mcna.2013.01.001","article-title":"International Work Group criteria for the diagnosis of Alzheimer disease","volume":"97","author":"Cummings","year":"2013","journal-title":"Med Clin North Am"},{"key":"10.1016\/j.jamda.2015.12.092_bib11","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.neuropharm.2013.07.004","article-title":"Therapeutics of Alzheimer's disease: Past, present and future","volume":"76","author":"Anand","year":"2014","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.jamda.2015.12.092_bib12","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/j.jalz.2015.02.009","article-title":"Early cost-utility analysis of general and cerebrospinal fluid-specific Alzheimer's disease biomarkers for hypothetical disease-modifying treatment decision in mild cognitive impairment","volume":"11","author":"Handels","year":"2015","journal-title":"Alzheimers Dement"},{"key":"10.1016\/j.jamda.2015.12.092_bib13","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1016\/S0140-6736(13)61570-6","article-title":"A\u00a0two-decade comparison of prevalence of dementia in individuals aged 65 years and older from three geographical areas of England: Results of the Cognitive Function and Ageing Study I and II","volume":"382","author":"Matthews","year":"2013","journal-title":"Lancet"},{"key":"10.1016\/j.jamda.2015.12.092_bib14","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.jalz.2012.11.007","article-title":"The global prevalence of dementia: A systematic review and meta-analysis","volume":"9","author":"Prince","year":"2013","journal-title":"Alzheimers Dement"},{"key":"10.1016\/j.jamda.2015.12.092_bib15","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1093\/gerona\/gls191","article-title":"Motoric cognitive risk syndrome and the risk of dementia","volume":"68","author":"Verghese","year":"2013","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"key":"10.1016\/j.jamda.2015.12.092_bib16","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1212\/WNL.0000000000000717","article-title":"Motoric cognitive risk syndrome: Multicountry prevalence and dementia risk","volume":"83","author":"Verghese","year":"2014","journal-title":"Neurology"},{"key":"10.1016\/j.jamda.2015.12.092_bib17","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1002\/mds.20897","article-title":"Changes in motor subtype and risk for incident dementia in Parkinson's disease","volume":"21","author":"Alves","year":"2006","journal-title":"Mov Disord"},{"key":"10.1016\/j.jamda.2015.12.092_bib18","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1001\/jama.292.12.1447","article-title":"Walking and dementia in physically capable elderly men","volume":"292","author":"Abbott","year":"2004","journal-title":"JAMA"},{"key":"10.1016\/j.jamda.2015.12.092_bib19","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1093\/gerona\/glr177","article-title":"Gait speed, body composition, and dementia. The EPIDOS-Toulouse cohort","volume":"67","author":"Abellan van Kan","year":"2012","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"key":"10.1016\/j.jamda.2015.12.092_bib20","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1001\/archneur.63.12.1763","article-title":"Motor dysfunction in mild cognitive impairment and the risk of incident Alzheimer disease","volume":"63","author":"Aggarwal","year":"2006","journal-title":"Arch Neurol"},{"key":"10.1016\/j.jamda.2015.12.092_bib21","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1159\/000107594","article-title":"Symptoms of preclinical dementia in general practice up to five years before dementia diagnosis","volume":"24","author":"Ramakers","year":"2007","journal-title":"Dement Geriatr Cogn Disord"},{"key":"10.1016\/j.jamda.2015.12.092_bib22","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1136\/jnnp.2006.106914","article-title":"Quantitative gait dysfunction and risk of cognitive decline and dementia","volume":"78","author":"Verghese","year":"2007","journal-title":"J\u00a0Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.jamda.2015.12.092_bib23","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1007\/s00702-007-0762-0","article-title":"High risk neurological gait syndrome and vascular dementia","volume":"114","author":"Verghese","year":"2007","journal-title":"J\u00a0Neural Transm"},{"key":"10.1016\/j.jamda.2015.12.092_bib24","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.jns.2004.11.009","article-title":"Gait slowing as a predictor of incident dementia: 6-year longitudinal data from the Sydney Older Persons Study","volume":"229\u2013230","author":"Waite","year":"2005","journal-title":"J\u00a0Neurol Sci"},{"key":"10.1016\/j.jamda.2015.12.092_bib25","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1001\/archinte.166.10.1115","article-title":"Performance-based physical function and future dementia in older people","volume":"166","author":"Wang","year":"2006","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.jamda.2015.12.092_bib26","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.jclinepi.2007.11.008","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: Guidelines for reporting observational studies","volume":"61","author":"von Elm","year":"2008","journal-title":"J\u00a0Clin Epidemiol"},{"key":"10.1016\/j.jamda.2015.12.092_bib27","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.jclinepi.2009.06.006","article-title":"The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: Explanation and elaboration","volume":"62","author":"Liberati","year":"2009","journal-title":"J\u00a0Clin Epidemiol"},{"key":"10.1016\/j.jamda.2015.12.092_bib28","unstructured":"Wells G, Shea B, O'Connell D, et\u00a0al. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. 2013. Available at: http:\/\/www.ohri.ca\/programs\/clinical_epidemiology\/oxford.asp. Accessed March 25,\u00a02015."},{"key":"10.1016\/j.jamda.2015.12.092_bib29","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/1741-7015-9-42","article-title":"Combinations of motor measures more strongly predict adverse health outcomes in old age: The rush memory and aging project, a community-based cohort study","volume":"9","author":"Buchman","year":"2011","journal-title":"BMC Med"},{"key":"10.1016\/j.jamda.2015.12.092_bib30","article-title":"Trajectory of mobility decline by type of dementia","author":"Tolea","year":"2015","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"10.1016\/j.jamda.2015.12.092_bib31","doi-asserted-by":"crossref","first-page":"e0122878","DOI":"10.1371\/journal.pone.0122878","article-title":"Longitudinal associations between physical and cognitive performance among community-dwelling older adults","volume":"10","author":"Tolea","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.jamda.2015.12.092_bib32","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1001\/archneurol.2010.159","article-title":"The trajectory of gait speed preceding mild cognitive impairment","volume":"67","author":"Buracchio","year":"2010","journal-title":"Arch Neurol"},{"key":"10.1016\/j.jamda.2015.12.092_bib33","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1212\/WNL.50.5.1496","article-title":"Motor slowing precedes cognitive impairment in the oldest old","volume":"50","author":"Camicioli","year":"1998","journal-title":"Neurology"},{"key":"10.1016\/j.jamda.2015.12.092_bib34","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1001\/archneur.59.4.601","article-title":"Independent predictors of cognitive decline in healthy elderly persons","volume":"59","author":"Marquis","year":"2002","journal-title":"Arch Neurol"},{"key":"10.1016\/j.jamda.2015.12.092_bib35","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1093\/gerona\/gls256","article-title":"Assessing the temporal relationship between cognition and gait: Slow gait predicts cognitive decline in the Mayo Clinic Study of Aging","volume":"68","author":"Mielke","year":"2013","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"key":"10.1016\/j.jamda.2015.12.092_bib36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1742-5573-8-1","article-title":"WINPEPI updated: Computer programs for epidemiologists, and their teaching potential","volume":"8","author":"Abramson","year":"2011","journal-title":"Epidemiol Perspect Innov"},{"key":"10.1016\/j.jamda.2015.12.092_bib37","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1002\/sim.1186","article-title":"Quantifying heterogeneity in a meta-analysis","volume":"21","author":"Higgins","year":"2002","journal-title":"Stat Med"},{"key":"10.1016\/j.jamda.2015.12.092_bib38","article-title":"Gait phenotype from mild cognitive impairment to moderate dementia: Results from the GOOD initiative","author":"Allali","year":"2015","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.jamda.2015.12.092_bib39","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1212\/WNL.0b013e318219fb08","article-title":"Biology of gait control: Vitamin D involvement","volume":"76","author":"Beauchet","year":"2011","journal-title":"Neurology"},{"key":"10.1016\/j.jamda.2015.12.092_bib40","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1111\/j.1532-5415.2005.53157.x","article-title":"Executive function correlates with walking speed in older persons: The InCHIANTI study","volume":"53","author":"Ble","year":"2005","journal-title":"J\u00a0Am Geriatr Soc"},{"key":"10.1016\/j.jamda.2015.12.092_bib41","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1007\/s00221-005-2280-3","article-title":"Walking is more like catching than tapping: Gait in the elderly as a complex cognitive task","volume":"164","author":"Hausdorff","year":"2005","journal-title":"Exp Brain Res"},{"key":"10.1016\/j.jamda.2015.12.092_bib42","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1743-0003-9-12","article-title":"Gait control: A specific subdomain of executive function?","volume":"9","author":"Beauchet","year":"2012","journal-title":"J\u00a0Neuroeng Rehabil"},{"key":"10.1016\/j.jamda.2015.12.092_bib43","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.gaitpost.2014.03.192","article-title":"Higher step length variability indicates lower gray matter integrity of selected regions in older adults","volume":"40","author":"Rosso","year":"2014","journal-title":"Gait Posture"},{"key":"10.1016\/j.jamda.2015.12.092_bib44","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1016\/j.neurobiolaging.2008.08.004","article-title":"Magnetization transfer imaging, white matter hyperintensities, brain atrophy and slower gait in older men and women","volume":"31","author":"Rosano","year":"2010","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.jamda.2015.12.092_bib45","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1159\/000111582","article-title":"Gait variability is associated with subclinical brain vascular abnormalities in high-functioning older adults","volume":"29","author":"Rosano","year":"2007","journal-title":"Neuroepidemiology"}],"container-title":["Journal of the American Medical Directors Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525861015008518?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525861015008518?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,4]],"date-time":"2019-09-04T08:09:21Z","timestamp":1567584561000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525861015008518"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6]]},"references-count":45,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,6]]}},"alternative-id":["S1525861015008518"],"URL":"https:\/\/doi.org\/10.1016\/j.jamda.2015.12.092","relation":{},"ISSN":["1525-8610"],"issn-type":[{"value":"1525-8610","type":"print"}],"subject":[],"published":{"date-parts":[[2016,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Poor Gait Performance and Prediction of Dementia: Results From a\u00a0Meta-Analysis","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Medical Directors Association","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jamda.2015.12.092","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 AMDA - The Society for Post-Acute and Long-Term Care Medicine.","name":"copyright","label":"Copyright"}]}}