{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T05:02:10Z","timestamp":1768971730553,"version":"3.49.0"},"reference-count":31,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jamda.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Medical Directors Association"],"published-print":{"date-parts":[[2017,5]]},"DOI":"10.1016\/j.jamda.2016.11.012","type":"journal-article","created":{"date-parts":[[2017,1,17]],"date-time":"2017-01-17T21:31:33Z","timestamp":1484688693000},"page":"409-413","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Cognitive Impairment Is Very Common in Elderly Patients With Syncope and Unexplained Falls"],"prefix":"10.1016","volume":"18","author":[{"given":"Susanne C.","family":"de Ruiter","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos F.M.","family":"de Jonghe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tjeerd","family":"Germans","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaap H.","family":"Ruiter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ren\u00e9 W.M.M.","family":"Jansen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jamda.2016.11.012_bib1","doi-asserted-by":"crossref","first-page":"2631","DOI":"10.1093\/eurheartj\/ehp298","article-title":"Guidelines for the diagnosis and management of syncope (version 2009)","volume":"30","year":"2009","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jamda.2016.11.012_bib2","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1093\/europace\/eus154","article-title":"The relation between age, sex, comorbidity, and pharmacotherapy and the risk of syncope: A Danish nationwide study","volume":"14","author":"Ruwald","year":"2012","journal-title":"Europace"},{"key":"10.1016\/j.jamda.2016.11.012_bib3","unstructured":"WHO Global Report On Falls Prevention in Older Age, 2007. World Health Organization (online). Available at: http:\/\/www.who.int\/ageing\/projects\/falls_prevention_older_age\/en\/. Accessed May 30,\u00a02016."},{"key":"10.1016\/j.jamda.2016.11.012_bib4","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1093\/ageing\/afi039","article-title":"Prevalence of cognitive impairment: Results from the MRC trial of assessment and management of older people in the community","volume":"34","author":"Rait","year":"2005","journal-title":"Age Ageing"},{"key":"10.1016\/j.jamda.2016.11.012_bib5","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1093\/gerona\/glt010","article-title":"Cognitive function modifies the effect of physiological function on the risk of multiple falls\u2014A population-based study","volume":"68","author":"Martin","year":"2013","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"key":"10.1016\/j.jamda.2016.11.012_bib6","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1093\/gerona\/glq115","article-title":"Cognition and the risk of hospitalization for serious falls in the elderly: Results from the cardiovascular health study","volume":"65","author":"Welmerink","year":"2010","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"key":"10.1016\/j.jamda.2016.11.012_bib7","doi-asserted-by":"crossref","first-page":"2130","DOI":"10.1111\/jgs.13081","article-title":"Is cognitive function a concern in independent elderly adults discharged home from the emergency department in Canada after a minor injury?","volume":"62","author":"Ouellet","year":"2015","journal-title":"J\u00a0Am Geriatr Soc"},{"key":"10.1016\/j.jamda.2016.11.012_bib8","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.archger.2011.06.004","article-title":"Risk of falls in 85-year-olds is associated with functional and cognitive status: The Octabaix Study","volume":"54","author":"Ferrer","year":"2012","journal-title":"Arch Gerontol Geriatr"},{"key":"10.1016\/j.jamda.2016.11.012_bib9","first-page":"48","article-title":"Mini-Mental State Exam domains predict falls in an elderly population: Follow-up from the Hispanic Established Populations for Epidemiologic Studies of the Elderly (H-EPESE) study","volume":"20","author":"Ramirez","year":"2010","journal-title":"Ethn Dis"},{"key":"10.1016\/j.jamda.2016.11.012_bib10","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.exger.2015.12.008","article-title":"Mild cognitive impairment is associated with falls among older adults: Findings from The Irish Longitudinal study on Ageing (TILDA)","volume":"75","author":"Tyrovolas","year":"2016","journal-title":"Exp Gerontol"},{"key":"10.1016\/j.jamda.2016.11.012_bib11","doi-asserted-by":"crossref","first-page":"e183","DOI":"10.1016\/j.archger.2010.08.012","article-title":"Characteristics associated with recurrent falls among the elderly within aged-care wards in a tertiary hospital: The effect of cognitive impairment","volume":"53","author":"Chen","year":"2011","journal-title":"Arch Gerontol Geriatr"},{"key":"10.1016\/j.jamda.2016.11.012_bib12","first-page":"719","article-title":"Falls and cognitive decline in Mexican Americans 75 years and older","volume":"9","author":"Padubidri","year":"2014","journal-title":"Clin Interv Aging"},{"key":"10.1016\/j.jamda.2016.11.012_bib13","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1093\/ageing\/afu191","article-title":"Recent syncope and unexplained falls are associated with poor cognitive performance","volume":"44","author":"Frewen","year":"2015","journal-title":"Age Ageing"},{"key":"10.1016\/j.jamda.2016.11.012_bib14","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.eurger.2015.05.007","article-title":"A\u00a0multidisciplinary care pathway for the evaluation of falls and syncope in geriatric patients: Specific care programme for the elders","volume":"6","author":"Wold","year":"2015","journal-title":"Eur Geriatr Med"},{"key":"10.1016\/j.jamda.2016.11.012_bib15","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1136\/pgmj.73.864.635","article-title":"The overlap between syncope and falls in the elderly","volume":"73","author":"Shaw","year":"1997","journal-title":"Postgrad Med J"},{"key":"10.1016\/j.jamda.2016.11.012_bib16","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1093\/europace\/eur069","article-title":"Amnesia for loss of consciousness is common in vasovagal syncope","volume":"13","author":"O'Dwyer","year":"2011","journal-title":"Europace"},{"key":"10.1016\/j.jamda.2016.11.012_bib17","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.jamda.2013.02.020","article-title":"Syncope","volume":"14","author":"Morley","year":"2013","journal-title":"J\u00a0Am Med Dir Assoc"},{"key":"10.1016\/j.jamda.2016.11.012_bib18","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"\u201cMini-Mental State.\u201d A practical method for grading the cognitive state of patients for the clinician","volume":"12","author":"Folstein","year":"1975","journal-title":"J\u00a0Psychiatr Res"},{"key":"10.1016\/j.jamda.2016.11.012_bib19","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1111\/j.1532-5415.2005.53221.x","article-title":"The Montreal Cognitive Assessment, MoCA: A brief screening tool for mild cognitive impairment","volume":"53","author":"Nasreddine","year":"2005","journal-title":"J\u00a0Am Geriatr Soc"},{"key":"10.1016\/j.jamda.2016.11.012_bib20","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1161\/STROKEAHA.110.579888","article-title":"Underestimation of cognitive impairment by Mini-Mental State Examination versus the Montreal Cognitive Assessment in patients with transient ischemic attack and stroke: A population-based study","volume":"41","author":"Pendlebury","year":"2010","journal-title":"Stroke"},{"key":"10.1016\/j.jamda.2016.11.012_bib21","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.jns.2007.01.029","article-title":"Mild cognitive impairment in symptomatic and asymptomatic cerebrovascular disease","volume":"257","author":"Popovi\u0107","year":"2007","journal-title":"J\u00a0Neurol Sci"},{"key":"10.1016\/j.jamda.2016.11.012_bib22","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.pcad.2012.11.006","article-title":"Epidemiology of syncope\/collapse in younger and older Western patient populations","volume":"55","author":"Kenny","year":"2013","journal-title":"Prog Cardiovasc Dis"},{"key":"10.1016\/j.jamda.2016.11.012_bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1749-6632.1996.tb34395.x","article-title":"In\u00a0vivo structural studies of the hippocampus in normal aging an in incipient Alzheimer's disease","volume":"777","author":"De Leon","year":"1996","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.jamda.2016.11.012_bib24","doi-asserted-by":"crossref","first-page":"351","DOI":"10.2214\/ajr.149.2.351","article-title":"MR signal abnormalities at 1.5 T in Alzheimer's dementia and normal aging","volume":"149","author":"Fazekas","year":"1987","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.jamda.2016.11.012_bib25","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.jpsychires.2008.04.014","article-title":"A\u00a0meta-analysis of the accuracy of the Mini-Mental State Examination in the detection of dementia and mild cognitive impairment","volume":"43","author":"Mitchell","year":"2009","journal-title":"J\u00a0Psychiatr Res"},{"key":"10.1016\/j.jamda.2016.11.012_bib26","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/0002-9343(86)90717-5","article-title":"Fall risk index for elderly patients based on number of chronic disabilities","volume":"80","author":"Tinetti","year":"1986","journal-title":"Am J Med"},{"key":"10.1016\/j.jamda.2016.11.012_bib27","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1111\/j.1532-5415.1991.tb01616.x","article-title":"The timed \u201cUp & Go\u201d: A test of basic functional mobility for frail elderly persons","volume":"39","author":"Podsiadlo","year":"1991","journal-title":"J\u00a0Am Geriatr Soc"},{"key":"10.1016\/j.jamda.2016.11.012_bib28","series-title":"Cognitive Screening Instruments: A Practical Approach","first-page":"111","article-title":"The Montreal Cognitive Assessment (MoCA): Concept and clinical review","author":"Julayanont","year":"2013"},{"key":"10.1016\/j.jamda.2016.11.012_bib29","doi-asserted-by":"crossref","first-page":"11","DOI":"10.2174\/1567205010666131119234845","article-title":"Impaired cerebral autoregulation and vasomotor reactivity in sporadic Alzheimer's disease","volume":"11","author":"Den Abeelen","year":"2014","journal-title":"Curr Alzheimer Res"},{"key":"10.1016\/j.jamda.2016.11.012_bib30","doi-asserted-by":"crossref","first-page":"609","DOI":"10.3233\/JAD-2012-120748","article-title":"Walking the cognitive \u201cminefield\u201d between high and low blood pressure","volume":"32","author":"Kennely","year":"2012","journal-title":"J\u00a0Alzheimers Dis"},{"key":"10.1016\/j.jamda.2016.11.012_bib31","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1136\/jnnp.55.10.967","article-title":"Atrophy of medial temporal lobes on MRI in \u201cprobable\u201d Alzheimer's disease and normal ageing: Diagnostic value and neuropsychological correlates","volume":"55","author":"Scheltens","year":"1992","journal-title":"J\u00a0Neurol Neurosurg Psychiatry"}],"container-title":["Journal of the American Medical Directors Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525861016305448?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525861016305448?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T03:12:41Z","timestamp":1754968361000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525861016305448"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5]]},"references-count":31,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["S1525861016305448"],"URL":"https:\/\/doi.org\/10.1016\/j.jamda.2016.11.012","relation":{},"ISSN":["1525-8610"],"issn-type":[{"value":"1525-8610","type":"print"}],"subject":[],"published":{"date-parts":[[2017,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cognitive Impairment Is Very Common in Elderly Patients With Syncope and Unexplained Falls","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Medical Directors Association","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jamda.2016.11.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 AMDA - The Society for Post-Acute and Long-Term Care Medicine.","name":"copyright","label":"Copyright"}]}}