{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T21:22:06Z","timestamp":1790630526166,"version":"4.1.0"},"reference-count":51,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004963","name":"Seventh Framework Programme","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004963","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jamda.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Medical Directors Association"],"published-print":{"date-parts":[[2019,9]]},"DOI":"10.1016\/j.jamda.2019.03.032","type":"journal-article","created":{"date-parts":[[2019,5,17]],"date-time":"2019-05-17T09:01:05Z","timestamp":1558083665000},"page":"1065-1073.e3","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Nonpharmacologic Management of Orthostatic Hypotension in Older People: A Systematic Review. The SENATOR ONTOP Series"],"prefix":"10.1016","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0322-9244","authenticated-orcid":false,"given":"Selvarani","family":"Subbarayan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3852-6158","authenticated-orcid":false,"given":"Phyo K.","family":"Myint","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn R.","family":"Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5440-775X","authenticated-orcid":false,"given":"Iosief","family":"Abraha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9992-8786","authenticated-orcid":false,"given":"Sirjana","family":"Devkota","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"O'Mahony","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfonso J.","family":"Cruz-Jentoft","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0261-9897","authenticated-orcid":false,"given":"Antonio","family":"Cherubini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roy L.","family":"Soiza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jamda.2019.03.032_bib1","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1161\/01.HYP.19.6.508","article-title":"Orthostatic hypotension in older adults. The Cardiovascular Health Study. CHS Collaborative Research Group","volume":"19","author":"Rutan","year":"1992","journal-title":"Hypertension"},{"key":"10.1016\/j.jamda.2019.03.032_bib2","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s10286-011-0119-5","article-title":"Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome","volume":"21","author":"Freeman","year":"2011","journal-title":"Clin Auton Res"},{"key":"10.1016\/j.jamda.2019.03.032_bib3","doi-asserted-by":"crossref","first-page":"107","DOI":"10.2143\/ACB.3215","article-title":"Prevalence of orthostatic hypotension and relationship with drug use amongst older patients","volume":"68","author":"Pepersack","year":"2013","journal-title":"Acta Clin Belg"},{"key":"10.1016\/j.jamda.2019.03.032_bib4","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1007\/s10286-007-1001-3","article-title":"Prevalence of orthostatic hypotension","volume":"18","author":"Low","year":"2008","journal-title":"Clin Auton Res"},{"key":"10.1016\/j.jamda.2019.03.032_bib5","article-title":"The prevalence of orthostatic hypotension: A systematic review and meta-analysis","author":"Saedon","year":"2018","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"key":"10.1016\/j.jamda.2019.03.032_bib6","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1038\/jhh.2008.81","article-title":"Postural changes in blood pressure and the prevalence of orthostatic hypotension among home-dwelling elderly aged 75 years or older","volume":"23","author":"Hiitola","year":"2009","journal-title":"J\u00a0Hum Hypertens"},{"key":"10.1016\/j.jamda.2019.03.032_bib7","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1111\/j.1365-2710.2005.00629.x","article-title":"High prevalence of orthostatic hypotension and its correlation with potentially causative medications among elderly veterans","volume":"30","author":"Poon","year":"2005","journal-title":"J\u00a0Clin Pharm Ther"},{"key":"10.1016\/j.jamda.2019.03.032_bib8","first-page":"583","article-title":"Postural fall in blood pressure in the elderly in relation to drug treatment and other lifestyle factors","volume":"84","author":"Burke","year":"1992","journal-title":"Q\u00a0J Med"},{"key":"10.1016\/j.jamda.2019.03.032_bib9","doi-asserted-by":"crossref","first-page":"105","DOI":"10.2165\/00002018-199717020-00003","article-title":"Drug-induced orthostatic hypotension in the elderly","volume":"17","author":"Verhaeverbeke","year":"1997","journal-title":"Drug Saf"},{"key":"10.1016\/j.jamda.2019.03.032_bib10","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/j.amjmed.2007.02.023","article-title":"Orthostatic hypotension in the elderly: Diagnosis and treatment","volume":"120","author":"Gupta","year":"2007","journal-title":"Am J Med"},{"key":"10.1016\/j.jamda.2019.03.032_bib11","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1586\/14779072.2015.1095090","article-title":"Orthostatic hypotension: Managing a difficult problem","volume":"13","author":"Jones","year":"2015","journal-title":"Expert Rev Cardiovasc Ther"},{"key":"10.1016\/j.jamda.2019.03.032_bib12","doi-asserted-by":"crossref","first-page":"298","DOI":"10.3949\/ccjm.77a.09118","article-title":"Preventing and treating orthostatic hypotension: As easy as A, B, C","volume":"77","author":"Figueroa","year":"2010","journal-title":"Cleve Clin J Med"},{"key":"10.1016\/j.jamda.2019.03.032_bib13","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1161\/HYPERTENSIONAHA.111.188151","article-title":"Orthostatic hypotension as a risk factor for incident heart failure: The Atherosclerosis Risk in Communities study","volume":"59","author":"Jones","year":"2012","journal-title":"Hypertension"},{"key":"10.1016\/j.jamda.2019.03.032_bib14","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1007\/s10741-016-9541-z","article-title":"Heart failure and orthostatic hypotension","volume":"21","author":"Gorelik","year":"2016","journal-title":"Heart Fail Rev"},{"key":"10.1016\/j.jamda.2019.03.032_bib15","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.ypmed.2016.01.007","article-title":"Orthostatic hypotension and the risk of incidental cardiovascular diseases: A meta-analysis of prospective cohort studies","volume":"85","author":"Xin","year":"2016","journal-title":"Prev Med"},{"key":"10.1016\/j.jamda.2019.03.032_bib16","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1016\/j.amjmed.2007.05.009","article-title":"Orthostatic hypotension-related hospitalizations in the United States","volume":"120","author":"Shibao","year":"2007","journal-title":"Am J Med"},{"key":"10.1016\/j.jamda.2019.03.032_bib17","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1007\/s11906-013-0362-3","article-title":"Current concepts in orthostatic hypotension management","volume":"15","author":"Arnold","year":"2013","journal-title":"Curr Hypertens Rep"},{"key":"10.1016\/j.jamda.2019.03.032_bib18","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/S0002-9343(99)00425-8","article-title":"The association between orthostatic hypotension and recurrent falls in nursing home residents","volume":"108","author":"Ooi","year":"2000","journal-title":"Am J Med"},{"key":"10.1016\/j.jamda.2019.03.032_bib19","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1136\/heartjnl-2013-304121","article-title":"Orthostatic hypotension and mortality risk: A meta-analysis of cohort studies","volume":"100","author":"Xin","year":"2014","journal-title":"Heart"},{"key":"10.1016\/j.jamda.2019.03.032_bib20","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1161\/CIRCULATIONAHA.105.598722","article-title":"Orthostatic hypotension predicts mortality in middle-aged adults: The Atherosclerosis Risk in Communities (ARIC) study","volume":"114","author":"Rose","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.jamda.2019.03.032_bib21","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1097\/CRD.0b013e31815c8032","article-title":"Pathophysiology, diagnosis, and treatment of orthostatic hypotension and vasovagal syncope","volume":"16","author":"Medow","year":"2008","journal-title":"Cardiol Rev"},{"key":"10.1016\/j.jamda.2019.03.032_bib22","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1111\/j.1468-1331.2006.01512.x","article-title":"EFNS guidelines on the diagnosis and management of orthostatic hypotension","volume":"13","author":"Lahrmann","year":"2006","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.jamda.2019.03.032_bib23","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.jash.2013.04.006","article-title":"Evaluation and treatment of orthostatic hypotension","volume":"7","author":"Shibao","year":"2013","journal-title":"J\u00a0Am Soc Hypertens"},{"key":"10.1016\/j.jamda.2019.03.032_bib24","first-page":"527","article-title":"Evaluation and management of orthostatic hypotension","volume":"84","author":"Lanier","year":"2011","journal-title":"Am Fam Physician"},{"key":"10.1016\/j.jamda.2019.03.032_bib25","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1177\/1060028016689264","article-title":"The treatment of primary orthostatic hypotension","volume":"51","author":"Hale","year":"2017","journal-title":"Ann Pharmacother"},{"key":"10.1016\/j.jamda.2019.03.032_bib26","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1111\/ijcp.12158","article-title":"Management of orthostatic hypotension","volume":"67","author":"Vassallo","year":"2013","journal-title":"Int J Clin Pract"},{"issue":"3","key":"10.1016\/j.jamda.2019.03.032_bib27","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1177\/2042098616675851","article-title":"The SENATOR project: Developing and\u00a0trialling a novel software engine to optimize medications and nonpharmacological therapy in older people with multimorbidity and polypharmacy","volume":"8","author":"Soiza","year":"2017","journal-title":"Ther Adv Drug Saf"},{"key":"10.1016\/j.jamda.2019.03.032_bib28","doi-asserted-by":"crossref","first-page":"e007488","DOI":"10.1136\/bmjopen-2014-007488","article-title":"Evidence of and recommendations for non-pharmacological interventions for common geriatric conditions: The SENATOR-ONTOP systematic review protocol","volume":"5","author":"Abraha","year":"2015","journal-title":"BMJ Open"},{"key":"10.1016\/j.jamda.2019.03.032_bib29","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.1212\/WNL.46.5.1470","article-title":"Consensus statement on the definition of orthostatic hypotension, pure autonomic failure, and multiple system atrophy","volume":"46","author":"Schatz","year":"1996","journal-title":"Neurology"},{"key":"10.1016\/j.jamda.2019.03.032_bib30","first-page":"9","article-title":"Systematic reviews explained: AMSTAR\u2014how to tell the good from the bad and the ugly","volume":"12","author":"Sharif","year":"2013","journal-title":"Oral Health Dent Manag"},{"key":"10.1016\/j.jamda.2019.03.032_bib31","series-title":"Cochrane Handbook for Systematic Reviews of Interventions: Version 5.1.0","year":"2014"},{"key":"10.1016\/j.jamda.2019.03.032_bib32","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.jclinepi.2010.04.026","article-title":"GRADE guidelines: 1. Introduction\u2014GRADE evidence profiles and summary of findings tables","volume":"64","author":"Guyatt","year":"2011","journal-title":"J\u00a0Clin Epidemiol"},{"key":"10.1016\/j.jamda.2019.03.032_bib34","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1159\/000081007","article-title":"Lower limb compression bandaging is effective in preventing signs and symptoms of seating-induced postural hypotension","volume":"102","author":"Gorelik","year":"2004","journal-title":"Cardiology"},{"key":"10.1016\/j.jamda.2019.03.032_bib35","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1159\/000141920","article-title":"Seating-induced postural hypotension is common in older patients with decompensated heart failure and may be prevented by lower limb compression bandaging","volume":"55","author":"Gorelik","year":"2009","journal-title":"Gerontology"},{"key":"10.1016\/j.jamda.2019.03.032_bib36","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1038\/sj.ki.5001852","article-title":"Treatment of post-dialytic orthostatic hypotension with an inflatable abdominal band in hemodialysis patients","volume":"70","author":"Yamamoto","year":"2006","journal-title":"Kidney Int"},{"key":"10.1016\/j.jamda.2019.03.032_bib37","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1002\/mdc3.12270","article-title":"Elastic abdominal binders attenuate orthostatic hypotension in Parkinson's disease","volume":"3","author":"Fanciulli","year":"2016","journal-title":"Mov Disord Clin Pract"},{"key":"10.1016\/j.jamda.2019.03.032_bib38","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.apmr.2014.10.012","article-title":"Effects of patient-controlled abdominal compression on standing systolic blood pressure in adults with orthostatic hypotension","volume":"96","author":"Figueroa","year":"2015","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.jamda.2019.03.032_bib39","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1016\/j.jacc.2006.06.052","article-title":"Lower limb and abdominal compression bandages prevent progressive orthostatic hypotension in elderly persons: A randomized single-blind controlled study","volume":"48","author":"Podoleanu","year":"2006","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jamda.2019.03.032_bib40","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0140-6736(99)02132-7","article-title":"Haemodynamic analysis of efficacy of compression hosiery in elderly fallers with orthostatic hypotension","volume":"354","author":"Henry","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.jamda.2019.03.032_bib41","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1093\/ageing\/afq176","article-title":"The effect of sleeping with the head of the bed elevated six inches on elderly patients with orthostatic hypotension: An open randomised controlled trial","volume":"40","author":"Fan","year":"2011","journal-title":"Age Ageing"},{"key":"10.1016\/j.jamda.2019.03.032_bib42","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/S0002-9343(02)01025-2","article-title":"Water drinking as a treatment for orthostatic syndromes","volume":"112","author":"Shannon","year":"2002","journal-title":"Am J Med"},{"key":"10.1016\/j.jamda.2019.03.032_bib43","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1007\/s10286-003-0117-3","article-title":"A\u00a0home-based resistance-training program using elastic bands for elderly patients with orthostatic hypotension","volume":"13","author":"Zion","year":"2003","journal-title":"Clin Auton Res"},{"key":"10.1016\/j.jamda.2019.03.032_bib44","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1002\/mds.21428","article-title":"Nonpharmacological treatment, fludrocortisone, and domperidone for orthostatic hypotension in Parkinson's disease","volume":"22","author":"Schoffer","year":"2007","journal-title":"Mov Disord"},{"key":"10.1016\/j.jamda.2019.03.032_bib45","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1111\/jgs.12759","article-title":"Lower limb and abdominal compression in the management of orthostatic hypotension\u2014Not supported by the evidence","volume":"62","author":"Frith","year":"2014","journal-title":"J\u00a0Am Geriatr Soc"},{"key":"10.1016\/j.jamda.2019.03.032_bib46","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.apmr.2014.09.028","article-title":"Nonpharmacologic management of orthostatic hypotension: A systematic review","volume":"96","author":"Mills","year":"2015","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.jamda.2019.03.032_bib47","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1093\/ageing\/afs061","article-title":"Efficacy of common treatments for orthostatic hypotension\u2014A systematic review","volume":"41","author":"Logan","year":"2012","journal-title":"Age Ageing"},{"key":"10.1016\/j.jamda.2019.03.032_bib48","doi-asserted-by":"crossref","first-page":"e652","DOI":"10.1212\/WNL.0000000000005994","article-title":"The efficacy of nonpharmacologic intervention for orthostatic hypotension associated with aging","volume":"91","author":"Newton","year":"2018","journal-title":"Neurology"},{"key":"10.1016\/j.jamda.2019.03.032_bib49","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/BF02291388","article-title":"Fludrocortisone and sleeping in the head-up position limit the postural decrease in cardiac output in autonomic failure","volume":"10","author":"van Lieshout","year":"2000","journal-title":"Clin Auton Res"},{"key":"10.1016\/j.jamda.2019.03.032_bib50","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/j.1365-2796.1992.tb00563.x","article-title":"Treatment of orthostatic hypotension with sleeping in the head-up tilt position, alone and in combination with fludrocortisone","volume":"232","author":"Harkel","year":"1992","journal-title":"J\u00a0Intern Med"},{"key":"10.1016\/j.jamda.2019.03.032_bib51","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1093\/eurheartj\/ehy037","article-title":"2018 ESC guidelines for the diagnosis and management of syncope","volume":"39","author":"Brignole","year":"2018","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jamda.2019.03.032_bib52","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s41999-018-0063-1","article-title":"Different patterns of orthostatic hypotension in older patients with unexplained falls or syncope: Orthostatic hypotension patterns in older people","volume":"9","author":"Roosendaal","year":"2018","journal-title":"Eur Geriatr Med"}],"container-title":["Journal of the American Medical Directors Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525861019303275?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525861019303275?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T19:18:43Z","timestamp":1761506323000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525861019303275"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":51,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2019,9]]}},"alternative-id":["S1525861019303275"],"URL":"https:\/\/doi.org\/10.1016\/j.jamda.2019.03.032","relation":{},"ISSN":["1525-8610"],"issn-type":[{"value":"1525-8610","type":"print"}],"subject":[],"published":{"date-parts":[[2019,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Nonpharmacologic Management of Orthostatic Hypotension in Older People: A Systematic Review. The SENATOR ONTOP Series","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Medical Directors Association","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jamda.2019.03.032","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 AMDA - The Society for Post-Acute and Long-Term Care Medicine.","name":"copyright","label":"Copyright"}]}}